Journal
ASIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 5, Issue 3, Pages 308-320Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.201600021
Keywords
BrOnsted acids; dynamic kinetic resolutions; enantioselectivity; organocatalysis; phosphoric acids
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Funding
- National Institutes of Health [GM116041]
- American Chemical Society Petroleum Research Fund [53916-DNI]
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The synthesis of enantioenriched small molecules is an ongoing goal of organic chemists. This Focus Review explores the use of kinetic resolutions catalyzed by chiral BrOnsted acids. Methods include classic kinetic resolutions and dynamic kinetic resolutions. The small molecules obtained are potentially valuable intermediates in the synthesis of biologically important compounds.
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