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Biomedical Metal-Organic Framework Materials: Perspectives and Challenges

ADVANCED FUNCTIONAL MATERIALS (2023)

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Article Multidisciplinary Sciences

A scalable metal-organic framework as a durable physisorbent for carbon dioxide capture

Jian-Bin Lin et al.

Summary: Zinc-based CALF-20 demonstrates high efficiency and cost-effectiveness in CO2 capture, with the ability to resist water interference, low regeneration cost, and strong durability.

SCIENCE (2021)

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Review Chemistry, Multidisciplinary

Nitric Oxide to Fight Viral Infections

Fabio Lisi et al.

Summary: COVID-19, caused by SARS-CoV-2, has had a significant global impact, with efforts being made to find effective treatments, such as nitric oxide, which has shown antiviral properties against coronaviruses. Despite its potential benefits, the complex role of NO in host immune responses to viral infections and challenges in its development for viral therapies are discussed, along with suggestions for further research.

ADVANCED SCIENCE (2021)

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Review Nanoscience & Nanotechnology

A reticular chemistry guide for the design of periodic solids

Hao Jiang et al.

Summary: Reticular chemistry has enabled the synthesis of diverse metalorganic frameworks and covalent organic frameworks through the linking of well-defined molecular building blocks into crystalline extended frameworks. The methodologies in this field are based on building blocks, targeted nets, and isoreticular chemistry, with emphasis on edge-transitive nets for the design of MOFs. Emerging concepts such as merged-net approach and net-coded building units show potential in synthesizing intricate or multi-component MOFs. Challenges and opportunities exist in the modification, expansion, and contraction of building blocks for the assembly of increasingly intricate frameworks.

NATURE REVIEWS MATERIALS (2021)

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Review Pharmacology & Pharmacy

Metal-organic frameworks for advanced drug delivery

Siyu He et al.

Summary: Metal-organic frameworks (MOFs) are highly porous, crystalline materials composed of organic ligands and metal ions/metal clusters. They are increasingly popular in drug delivery due to their tunable porosity, chemical composition, and surface functionalization capabilities. Despite their potential in biomedical applications, challenges such as biostability and biosafety need to be addressed in the development of MOFs for drug delivery systems.

ACTA PHARMACEUTICA SINICA B (2021)

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Article Engineering, Biomedical

Antibacterial Zeolite Imidazole Frameworks with Manganese Doping for Immunomodulation to Accelerate Infected Wound Healing

Yao Wan et al.

Summary: A strategy of introducing enzymatic activity into nanomaterials for antibacterial and anti-inflammatory effects is introduced, showing dual functionality for treating bacterial infected wounds. This simple metal organic framework design effectively combines the enzymatic activity of manganese ions with the pore structure advantages of ZIF-8.

ADVANCED HEALTHCARE MATERIALS (2021)

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Review Chemistry, Multidisciplinary

25 Years of Reticular Chemistry

Ralph Freund et al.

Summary: The core of reticular chemistry has brought precision and expertise of organic and inorganic synthesis to the solid state. The most profound scientific innovation of this field has been the design strategies for the synthesis of extended crystalline solids through strong directional bonds, highlighting the different classes of reticular materials developed and how complexity can be introduced into their backbones. Structural control over these materials is being extended from the molecular scale to their crystal morphology and shape on the nanoscale, all the way to their shaping on the bulk scale.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

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Review Chemistry, Multidisciplinary

The Current Status of MOF and COF Applications

Ralph Freund et al.

Summary: The amalgamation of different disciplines at the heart of reticular chemistry has broadened the boundaries of chemistry. Reticular design enables precise prediction of crystalline framework structures, tunability of chemical composition, and fine-tuning of material properties in metal-organic frameworks and covalent organic frameworks. Leveraging the unique properties of reticular materials has led to significant advances in both fundamental and applied research.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

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Article Chemistry, Physical

The changing state of porous materials

Thomas D. Bennett et al.

Summary: Porous materials are usually ordered crystalline solids, but topological disorder may also be useful in creating alternative properties. This research explores the evolution from ordered states to glassy and liquid states, different types of porous liquids, and potential applications of these disordered systems.

NATURE MATERIALS (2021)

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Review Biotechnology & Applied Microbiology

Emerging concepts in the science of vaccine adjuvants

Bali Pulendran et al.

Summary: Adjuvants are vaccine components that enhance the immune response. Recent advances in understanding the molecular mechanisms and systems vaccinology have revitalized the science and development of novel adjuvants for use in vaccines against COVID-19 and future pandemics.

NATURE REVIEWS DRUG DISCOVERY (2021)

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Article Cell Biology

Advanced bandages for diabetic wound healing

Simon Matoori et al.

Summary: The study reviews current treatment options for foot ulcers related to diabetes and discusses the development of wound dressings tailored to the diabetic wound environment.

SCIENCE TRANSLATIONAL MEDICINE (2021)

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Review Chemistry, Multidisciplinary

Chemical targets to deactivate biological and chemical toxins using surfaces and fabrics

Christia R. Jabbour et al.

Summary: To prepare for the next global threat, it is crucial to develop environments where infectious diseases and dangerous chemicals cannot be easily spread or misused, especially for those in high exposure situations who need adequate protection. Recent studies have shown that the use of metal and metal-oxide catalysts, as well as metal-organic frameworks, can help accelerate the inactivation of biological and chemical toxins.

NATURE REVIEWS CHEMISTRY (2021)

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Review Chemistry, Multidisciplinary

Functional Hydrogels as Wound Dressing to Enhance Wound Healing

Yongping Liang et al.

Summary: Hydrogels have shown promising advantages as wound dressings due to their excellent biochemical and mechanical properties. This review summarizes the advanced functions of hydrogel dressings, such as antimicrobial, adhesion, hemostasis, anti-inflammatory, substance delivery, self-healing, stimulus response, and conductivity, as well as the emerging wound monitoring feature. The potential applications for different types of wounds, including chronic wounds and focus on infected, burn, and diabetic wounds, are discussed, along with proposed future directions for hydrogel wound dressings in wound healing.

ACS NANO (2021)

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Article Chemistry, Multidisciplinary

Metal-Organic Framework Encapsulated Whole-Cell Vaccines Enhance Humoral Immunity against Bacterial Infection

Michael A. Luzuriaga et al.

Summary: The increasing resistance of bacterial infections to antibiotics calls for next generation approaches to prevent potential pandemics. The development of vaccines against pathogenic bacteria has been challenging due to genetic diversity, but enhancing immunogenicity through slow releasing depots can significantly improve immune responses and survival rates.

ACS NANO (2021)

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Article Chemistry, Multidisciplinary

A pH-Triggered Self-Unpacking Capsule Containing Zwitterionic Hydrogel-Coated MOF Nanoparticles for Efficient Oral Exendin-4 Delivery

Yuhao Zhou et al.

Summary: Oral delivery of peptides or proteins through a pH-triggered self-unpacking capsule can improve bioavailability by enhancing penetration in the gastrointestinal environment and intestinal mucosa. This strategy significantly increases plasma levels of exendin-4, boosts endogenous insulin secretion, and effectively lowers blood glucose levels.

ADVANCED MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Smart biomimetic metal organic frameworks based on ROS-ferroptosis-glycolysis regulation for enhanced tumor chemo-immunotherapy

Jie Yang et al.

Summary: The study developed a cancer cell membrane coated metal organic framework nanoplatform, utilizing ROS-ferroptosis-glycolysis regulation to inhibit tumor growth and enhance antitumor immunity.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Chemistry, Multidisciplinary

Scalable Room-Temperature Synthesis of Highly Robust Ethane-Selective Metal-Organic Frameworks for Efficient Ethylene Purification

Shubo Geng et al.

Summary: The study introduced two new C2H6-selective MOF adsorbents with high stability and selectivity, which can effectively separate ethylene from ethane even in high humidity conditions. The scalable synthesis method and potential industrial applications make them promising for practical use in industrial settings.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

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Article Chemistry, Multidisciplinary

Iodine Immobilized Metal-Organic Framework for NIR-Triggered Antibacterial Therapy on Orthopedic Implants

Wangsiyuan Teng et al.

Summary: By leveraging the superior absorption capability of metal-organic frameworks (MOFs) and their inherent photocatalytic properties, iodine-loaded MOF surface is presented to achieve responsive iodine release and intracellular ROS oxidation under near-infrared exposure for synergistic antibacterial effect.

SMALL (2021)

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Review Biotechnology & Applied Microbiology

Artificial exosomes for translational nanomedicine

Yong-Jiang Li et al.

Summary: Artificial exosomes, produced through nanobiotechnology, have emerged as effective drug delivery carriers and include various types such as nanovesicles, exosome-mimetic, and hybrid exosomes. These artificial exosomes offer solutions to overcome limitations of natural exosomes and are considered powerful alternatives for drug delivery.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

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Article Materials Science, Biomaterials

Highly Efficient Encapsulation of Doxorubicin Hydrochloride in Metal-Organic Frameworks for Synergistic Chemotherapy and Chemodynamic Therapy

Lijia Yao et al.

Summary: Iron-based metal-organic frameworks show potential for high loading capacity and efficient encapsulation of doxorubicin hydrochloride (DOX), a widely used anticancer drug. The synthesized water-stable nano-MOFs effectively adsorbed deprotonated DOX electrostatically and released the drug and Fe(III) ions under GSH and ATP stimulation, leading to a Fenton-like reaction generating highly toxic hydroxyl radicals for effective cancer cell inhibition.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2021)

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Review Chemistry, Multidisciplinary

Haemostatic materials for wound healing applications

Baolin Guo et al.

Summary: Wounds are a common health issue, and the cost of wound care and healing has been increasing. Hemostasis is the first step in wound healing, and various forms and components of hemostatic materials have been developed. Future directions in the development of hemostatic materials focus on addressing challenges in wound healing.

NATURE REVIEWS CHEMISTRY (2021)

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Review Biotechnology & Applied Microbiology

Nanoparticles in the clinic: An update post COVID-19 vaccines

Aaron C. Anselmo et al.

Summary: Nanoparticles serve as a crucial technology in treating cancer, imaging tissues, and facilitating vaccination. The recent Emergency Use Authorization of COVID-19 lipid nanoparticle vaccines has highlighted the potential of nanoparticles as delivery vehicles in the forefront of biotechnology.

BIOENGINEERING & TRANSLATIONAL MEDICINE (2021)

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Review Materials Science, Biomaterials

Gas and gas-generating nanoplatforms in cancer therapy

Yuan-Zhe Jing et al.

Summary: Gas therapy involves using specific gases with therapeutic effects to treat diseases, including hydrogen, nitric oxide, carbon monoxide, and hydrogen sulfide. These gases can directly impact cell function, leading to cell apoptosis, and also influence the phenotype conversion of tumor-associated macrophages.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Article Chemistry, Multidisciplinary

Tuning water adsorption, stability, and phase in Fe-MIL-101 and Fe-MIL-88 analogs with amide functionalization

Andrew Kuznicki et al.

Summary: The MIL series of metal-organic frameworks (MOFs) have been widely studied for their high tunability and diversity of structure types. Using amide-functionalized ligands in the synthesis of Fe-MIL-101 can tune water stability and water vapor adsorption in these frameworks. Slow leaching of Fe from NdFeB magnets can produce MIL-101 or MIL-88 under various conditions, where the framework phase is controlled by the length of carbon chains on amide substituents.

CHEMICAL COMMUNICATIONS (2021)

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Article Chemistry, Physical

MOFs industrialization: a complete assessment of production costs

Maria Ines Severino et al.

Summary: The study evaluated the potential of safe and low-cost batch production processes for Metal-Organic Frameworks (MOFs), finding that high practical value bio-derived materials can be produced with high yield using green ambient pressure conditions. By considering all process parameters and using data from laboratory tests, the production cost was determined, with future expected costs projected to decrease further.

FARADAY DISCUSSIONS (2021)

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Review Materials Science, Biomaterials

Recent advances in the development of nitric oxide-releasing biomaterials and their application potentials in chronic wound healing

Min Wu et al.

Summary: Nitric oxide (NO) plays a critical role in chronic wound healing, attracting intensive research focus on NO-based wound healing therapy. Various types of NO donors, biomaterial vectors, and NO delivery systems have been developed, along with NO synthetic enzyme mimics, to improve chronic wound healing. The functions of NO releasing biomaterials, such as antibacterial properties and promotion of angiogenesis, as well as the potential combination with light/thermal therapies, hold promise for advancing chronic wound healing.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Review Chemistry, Multidisciplinary

Metal-organic frameworks as photoluminescent biosensing platforms: mechanisms and applications

Yifang Zhao et al.

Summary: Biosensing plays a crucial role in monitoring abnormalities in biological systems and advancing public health, with MOF materials offering immense feasibility in the construction of biosensing platforms.

CHEMICAL SOCIETY REVIEWS (2021)

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Article Chemistry, Multidisciplinary

A novel route to size-controlled MIL-53(Fe) metal-organic frameworks for combined chemodynamic therapy and chemotherapy for cancer

Anxia Li et al.

Summary: A new method was developed to synthesize controlled-size MIL-53(Fe) nanocrystals for cancer treatment by adding PVP as a surfactant to improve the growth process. This approach can produce uniform-shaped MIL-53(Fe) nanocrystals with the potential to improve drug release and treatment effects.

RSC ADVANCES (2021)

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Article Chemistry, Multidisciplinary

Defect-engineered porphyrinic metal-organic framework nanoparticles for targeted multimodal cancer phototheranostics†

Chenyuan Wang et al.

Summary: This study fabricated defect-engineered porphyrinic MOF nanoparticles using cypate as a co-ligand and modulator, integrating the photothermal and multimodal imaging properties of cypate with the photodynamic effects of porphyrins to achieve targeted multimodal cancer phototheranostics.

CHEMICAL COMMUNICATIONS (2021)

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Article Materials Science, Biomaterials

Copper-doped metal-organic frameworks for the controlled generation of nitric oxide from endogenous S-nitrosothiols

Yingzhu Zhou et al.

Summary: The study reports the synthesis of a catalyst, copper-doped zeolitic imidazolate framework ZIF-8 (Cu2+/ZIF-8), designed to generate nitric oxide from naturally occurring endogenous NO donors. By tuning the copper doping percentages, controlled NO generation from S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO) was achieved. The copper-doped ZIF-8 catalyst showed a 10-fold increased amount of NO compared to previous reports, demonstrating its potential in dispersing bacterial biofilms in the presence of GSNO.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Article Chemistry, Multidisciplinary

Modular Assembly of Red Blood Cell Superstructures from Metal-Organic Framework Nanoparticle-Based Building Blocks

Jimin Guo et al.

Summary: Armored red blood cells are a new type of hybrid biomaterials with native red blood cells assembled within and protected by a functional exoskeleton of interconnected MOF nanoparticles. The formation of exoskeletons is rapid and based on metal-phenolic coordination and hydrogen-bonding interactions. Armored RBCs retain the original properties of RBCs and demonstrate enhanced resistance against external stressors, offering potential applications in blood nitric oxide sensing or multimodal imaging.

ADVANCED FUNCTIONAL MATERIALS (2021)

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Article Nanoscience & Nanotechnology

Metal-Organic Framework/Ag-Based Hybrid Nanoagents for Rapid and Synergistic Bacterial Eradication

Ye Yang et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Nanoscience & Nanotechnology

Composition-Engineered Metal-Organic Framework-Based Microneedles for Glucose-Mediated Transdermal Insulin Delivery

Xiao-Xi Yang et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Chemistry, Multidisciplinary

A Metal-Organic Framework (MOF) Fenton Nanoagent-Enabled Nanocatalytic Cancer Therapy in Synergy with Autophagy Inhibition

Bowen Yang et al.

ADVANCED MATERIALS (2020)

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Article Engineering, Biomedical

A pH/Ultrasound dual-response biomimetic nanoplatform for nitric oxide gas-sonodynamic combined therapy and repeated ultrasound for relieving hypoxia

Jie An et al.

BIOMATERIALS (2020)

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Review Chemistry, Multidisciplinary

Metal-Organic Frameworks for the Removal of Emerging Organic Contaminants in Water

Sara Rojas et al.

CHEMICAL REVIEWS (2020)

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Article Environmental Sciences

Iron-copper bimetallic metal-organic frameworks for efficient Fenton-like degradation of sulfamethoxazole under mild conditions

Juntao Tang et al.

CHEMOSPHERE (2020)

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Article Medicine, General & Internal

Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018

Olivier J. Wouters et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

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Article Chemistry, Multidisciplinary

Engineering of Upconverted Metal-Organic Frameworks for Near-Infrared Light-Triggered Combinational Photodynamic/Chemo-/Immunotherapy against Hypoxic Tumors

Yulei Shao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

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Article Chemistry, Multidisciplinary

Cell-Type-Specific CRISPR/Cas9 Delivery by Biomimetic Metal Organic Frameworks

Mram Z. Alyami et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

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Review Chemistry, Multidisciplinary

Metal-Organic Frameworks for Biomedical Applications

Jie Yang et al.

SMALL (2020)

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Article Nanoscience & Nanotechnology

Bio-Inspired Polydopamine-Mediated Zr-MOF Fabrics for Solar Photothermal-Driven Instantaneous Detoxification of Chemical Warfare Agent Simulants

Aonan Yao et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Nanoscience & Nanotechnology

Metal-Organic Framework Traps with Record-High Bilirubin Removal Capacity for Hemoperfusion Therapy

Qingsi Li et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Nanoscience & Nanotechnology

A Nanocomposite Vehicle Based on Metal-Organic Framework Nanoparticle Incorporated Biodegradable Microspheres for Enhanced Oral Insulin Delivery

Yuhao Zhou et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Chemistry, Multidisciplinary

Full-Process Radiosensitization Based on Nanoscale Metal-Organic Frameworks

Teng Gong et al.

ACS NANO (2020)

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Article Chemistry, Multidisciplinary

Metal-Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH

Evelyn Ploetz et al.

ADVANCED MATERIALS (2020)

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Review Chemistry, Multidisciplinary

Metal-Organic Frameworks in Heterogeneous Catalysis: Recent Progress, New Trends, and Future Perspectives

Anastasiya Bavykina et al.

CHEMICAL REVIEWS (2020)

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Article Chemistry, Multidisciplinary

pH-sensitive MOF integrated with glucose oxidase for glucose-responsive insulin delivery

Cheng Zhang et al.

JOURNAL OF CONTROLLED RELEASE (2020)

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Review Nanoscience & Nanotechnology

Metal-Organic Framework Nanocarriers for Drug Delivery in Biomedical Applications

Yujia Sun et al.

NANO-MICRO LETTERS (2020)

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Review Chemistry, Multidisciplinary

Stealth Coating of Nanoparticles in Drug-Delivery Systems

See Yee Fam et al.

NANOMATERIALS (2020)

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Article Instruments & Instrumentation

Challenges in nanomedicine clinical translation

Josbert M. Metselaar et al.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2020)

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Article Multidisciplinary Sciences

Targeted gene silencing in vivo by platelet membrane-coated metal-organic framework nanoparticles

Jia Zhuang et al.

SCIENCE ADVANCES (2020)

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Article Multidisciplinary Sciences

Highly bioactive zeolitic imidazolate framework-8-capped nanotherapeutics for efficient reversal of reperfusion-induced injury in ischemic stroke

Lizhen He et al.

SCIENCE ADVANCES (2020)

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Article Nanoscience & Nanotechnology

Evaluating UiO-66 Metal-Organic Framework Nanoparticles as Acid-Sensitive Carriers for Pulmonary Drug Delivery Applications

Bader M. Jarai et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Engineering, Biomedical

Site-specific MOF-based immunotherapeutic nanoplatforms via synergistic tumor cells-targeted treatment and dendritic cells-targeted immunomodulation

Huiyuan Zhang et al.

BIOMATERIALS (2020)

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Article Chemistry, Multidisciplinary

Metal-Organic Frameworks for Water Harvesting from Air, Anywhere, Anytime

Wentao Xu et al.

ACS CENTRAL SCIENCE (2020)

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Article Multidisciplinary Sciences

Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy

Yufeng Liu et al.

SCIENCE ADVANCES (2020)

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Article Chemistry, Multidisciplinary

What Went Wrong with Anticancer Nanomedicine Design and How to Make It Right

Duxin Sun et al.

ACS NANO (2020)

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Article Chemistry, Physical

Pore Size and Porosity Dependent Zeta Potentials of Mesoporous Silica Nanoparticles

Fetiye Esin Yakin et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2020)

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Article Oncology

Pre-clinical animal models are poor predictors of human toxicities in phase 1 oncology clinical trials

Johnique T. Atkins et al.

BRITISH JOURNAL OF CANCER (2020)

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Article Multidisciplinary Sciences

A nanoscale metal organic frameworks-based vaccine synergises with PD-1 blockade to potentiate anti-tumour immunity

Xia Li et al.

NATURE COMMUNICATIONS (2020)

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Article Multidisciplinary Sciences

Understanding the diversity of the metal-organic framework ecosystem

Seyed Mohamad Moosavi et al.

NATURE COMMUNICATIONS (2020)

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Review Chemistry, Multidisciplinary

Utilization of zeolites as CO2 capturing agents: Advances and future perspectives

Santosh Kumar et al.

JOURNAL OF CO2 UTILIZATION (2020)

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Article Chemistry, Multidisciplinary

Porous Aromatic Framework with Tailored Binding Sites and Pore Sizes as a High-Performance Hemoperfusion Adsorbent for Bilirubin Removal

Rui Zhao et al.

ADVANCED SCIENCE (2020)

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Article Multidisciplinary Sciences

Nanoscale metal-organic frameworks for x-ray activated in situ cancer vaccination

Kaiyuan Ni et al.

SCIENCE ADVANCES (2020)

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Article Chemistry, Multidisciplinary

Dissolution Enhancement and Controlled Release of Paclitaxel Drug via a Hybrid Nanocarrier Based on mPEG-PCL Amphiphilic Copolymer and Fe-BTC Porous Metal-Organic Framework

Nikolaos D. Bikiaris et al.

NANOMATERIALS (2020)

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Article Materials Science, Multidisciplinary

Antibacterial efficacy from NO-releasing MOF-polymer films

Morven J. Duncan et al.

MATERIALS ADVANCES (2020)

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Article Chemistry, Multidisciplinary

3D printing of metal-organic framework incorporated porous scaffolds to promote osteogenic differentiation and bone regeneration

Linna Zhong et al.

NANOSCALE (2020)

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Review Chemistry, Inorganic & Nuclear

Metal organic framework top-down and bottom-up patterning techniques

Cesar L. Ruiz-Zambrana et al.

DALTON TRANSACTIONS (2020)

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Review Chemistry, Multidisciplinary

Emerging combination strategies with phototherapy in cancer nanomedicine

Zhongjian Xie et al.

CHEMICAL SOCIETY REVIEWS (2020)

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Article Pharmacology & Pharmacy

Clinically Approved MRI Contrast Agents as Imaging Labels for a Porous Iron-Based MOF Nanocarrier: A Systematic Investigation in a Clinical MRI Setting

Konstantin Boell et al.

ADVANCED THERAPEUTICS (2020)

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Article Chemistry, Physical

Design of stable mixed-metal MIL-101(Cr/Fe) materials with enhanced catalytic activity for the Prins reaction

Cristina Valles-Garcia et al.

JOURNAL OF MATERIALS CHEMISTRY A (2020)

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Article Nanoscience & Nanotechnology

FePt Nanoparticles Embedded in Metal-Organic Framework Nanoparticles for Tumor Imaging and Eradication

Yanfei Meng et al.

ACS APPLIED NANO MATERIALS (2020)

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Article Chemistry, Multidisciplinary

Metal organic frameworks as a compatible reinforcement in a biopolymer bone scaffold

Youwen Yang et al.

MATERIALS CHEMISTRY FRONTIERS (2020)

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Article Chemistry, Multidisciplinary

An intelligent ZIF-8-gated polydopamine nanoplatform for in vivo cooperatively enhanced combination phototherapy

Jie Feng et al.

CHEMICAL SCIENCE (2020)

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Article Chemistry, Multidisciplinary

DNAzyme-Loaded Metal-Organic Frameworks (MOFs) for Self-Sufficient Gene Therapy

Huimin Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Article Chemistry, Multidisciplinary

Zirconium-Based Metal-Organic Frameworks for the Removal of Protein-Bound Uremic Toxin from Human Serum Albumin

Satoshi Kato et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

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Article Chemistry, Multidisciplinary

DNA-Functionalized Metal-Organic Framework Nanoparticles for Intracellular Delivery of Proteins

Shunzhi Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

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Review Pharmacology & Pharmacy

Challenges and Recent Progress in Oral Drug Delivery Systems for Biopharmaceuticals

Bahman Homayun et al.

PHARMACEUTICS (2019)

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Article Nanoscience & Nanotechnology

Ti-Based nanoMOF as an Efficient Oral Therapeutic Agent

Sara Rojas et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Chemistry, Multidisciplinary

SupraCells: Living Mammalian Cells Protected within Functional Modular Nanoparticle-Based Exoskeletons

Wei Zhu et al.

ADVANCED MATERIALS (2019)

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Article Chemistry, Multidisciplinary

A Catalase-Like Metal-Organic Framework Nanohybrid for O2-Evolving Synergistic Chemoradiotherapy

Zhimei He et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Article Chemistry, Multidisciplinary

Metal-Organic Framework Nanoparticle-Assisted Cryopreservation of Red Blood Cells

Wei Zhu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

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Article Chemistry, Multidisciplinary

Monodispersed Copper(I)-Based Nano Metal-Organic Framework as a Biodegradable Drug Carrier with Enhanced Photodynamic Therapy Efficacy

Xuechao Cai et al.

ADVANCED SCIENCE (2019)

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Article Chemistry, Multidisciplinary

Thermal-Responsive Carbon Monoxide (CO) Delivery Expedites Metabolic Exhaustion of Cancer Cells toward Reversal of Chemotherapy Resistance

Yongjuan Li et al.

ACS CENTRAL SCIENCE (2019)

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Review Chemistry, Multidisciplinary

Nanoparticle Characterization: What to Measure?

Mario M. Modena et al.

ADVANCED MATERIALS (2019)

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Article Chemistry, Multidisciplinary

Encapsulation of Plasmid DNA by Nanoscale Metal-Organic Frameworks for Efficient Gene Transportation and Expression

Yantao Li et al.

ADVANCED MATERIALS (2019)

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Article Engineering, Biomedical

Immobilization of nano Cu-MOFs with polydopamine coating for adaptable gasotransmitter generation and copper ion delivery on cardiovascular stents

Yonghong Fan et al.

BIOMATERIALS (2019)

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Article Materials Science, Paper & Wood

Three-dimensional cellulose-hydroxyapatite nanocomposite enriched with dexamethasone loaded metal-organic framework: a local drug delivery system for bone tissue engineering

Chandrani Sarkar et al.

CELLULOSE (2019)

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Article Chemistry, Physical

Bioactive and anti-corrosive bio-MOF-1 coating on magnesium alloy for bone repair application

Wei Liu et al.

JOURNAL OF ALLOYS AND COMPOUNDS (2019)

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Letter Nanoscience & Nanotechnology

Setting standards to promote progress in bio-nano science

Twan Lammers et al.

NATURE NANOTECHNOLOGY (2019)

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Article Chemistry, Multidisciplinary

Encapsulation, Visualization and Expression of Genes with Biomimetically Mineralized Zeolitic Imidazolate Framework-8 (ZIF-8)

Arpita Poddar et al.

SMALL (2019)

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Article Chemistry, Multidisciplinary

Metal-Organic-Framework-Derived Carbon Nanostructures for Site-Specific Dual-Modality Photothermal/Photodynamic Thrombus Therapy

Fengrong Zhang et al.

ADVANCED SCIENCE (2019)

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Review Chemistry, Multidisciplinary

Gas-Mediated Cancer Bioimaging and Therapy

Lichan Chen et al.

ACS NANO (2019)

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Article Engineering, Biomedical

Fabrication of magnesium/zinc-metal organic framework on titanium implants to inhibit bacterial infection and promote bone regeneration

Xinkun Shen et al.

BIOMATERIALS (2019)

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Article Oncology

NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act. In. Sarc): a multicentre, phase 2-3, randomised, controlled trial

Sylvie Bonvalot et al.

LANCET ONCOLOGY (2019)

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Editorial Material Chemistry, Multidisciplinary

Reticular Chemistry in All Dimensions

Omar M. Yaghi

ACS CENTRAL SCIENCE (2019)

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Article Chemistry, Multidisciplinary

Enhanced Drug Delivery by Dissolution of Amorphous Drug Encapsulated in a Water Unstable Metal-Organic Framework (MOF)

Kuthuru Suresh et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Article Nanoscience & Nanotechnology

Smart cancer nanomedicine

Roy van der Meel et al.

NATURE NANOTECHNOLOGY (2019)

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Article Pharmacology & Pharmacy

Drug nanoclusters formed in confined nano-cages of CD-MOF: dramatic enhancement of solubility and bioavailability of azilsartan

Yuanzhi He et al.

ACTA PHARMACEUTICA SINICA B (2019)

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Article Nanoscience & Nanotechnology

Antibacterial Countermeasures via Metal-Organic Framework Supported Sustained Therapeutic Release

Dorina F. Sava Gallis et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Nanoscience & Nanotechnology

Enhanced Stability and Controlled Delivery of MOF-Encapsulated Vaccines and Their Immunogenic Response In Vivo

Michael A. Luzuriaga et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface

Andreas Zimpel et al.

ACS NANO (2019)

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The highly efficient elimination of intracellular bacteria via a metal organic framework (MOF)-based three-in-one delivery system

Xu Zhang et al.

NANOSCALE (2019)

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Metal-organic frameworks: a universal strategy towards super-elastic hydrogels

Huaizhi Liu et al.

POLYMER CHEMISTRY (2019)

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Nanoparticles in the clinic: An update

Aaron C. Anselmo et al.

BIOENGINEERING & TRANSLATIONAL MEDICINE (2019)

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Core-Shell Functionalized Zirconium-Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content

Benjamin Steinborn et al.

ADVANCED THERAPEUTICS (2019)

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Improving MOF stability: approaches and applications

Meili Ding et al.

CHEMICAL SCIENCE (2019)

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Therapeutic efficacy of nanoparticles and routes of administration

Dhrisya Chenthamara et al.

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Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework

Shahad K. Alsaiari et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

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Copper Metal-Organic Framework Nanoparticles Stabilized with Folic Acid Improve Wound Healing in Diabetes

Jisheng Xiao et al.

ACS NANO (2018)

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Multifunctional Efficiency: Extending the Concept of Atom Economy to Functional Nanomaterials

Ralph Freund et al.

ACS NANO (2018)

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Glucose-Responsive Metal-Organic-Framework Nanoparticles Act as Smart Sense-and-Treat Carriers

Wei-Hai Chen et al.

ACS NANO (2018)

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Oxygen-Generating MnO2 Nanodots-Anchored Versatile Nanoplatform for Combined Chemo-Photodynamic Therapy in Hypoxic Cancer

Wentao Zhang et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

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Metal-Organic-Framework-Assisted In Vivo Bacterial Metabolic Labeling and Precise Antibacterial Therapy

Duo Mao et al.

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Rational design of a stable, effective, and sustained dexamethasone delivery platform on a titanium implant: An innovative application of metal organic frameworks in bone implants

Jiabing Ran et al.

CHEMICAL ENGINEERING JOURNAL (2018)

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Acid-Resistant Mesoporous Metal-Organic Framework toward Oral Insulin Delivery: Protein Encapsulation, Protection, and Release

Yijing Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

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Metal-Organic Frameworks as Efficient Oral Detoxifying Agents

Sara Rojas et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

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Recent advances in gas storage and separation using metal-organic frameworks

Hao Li et al.

MATERIALS TODAY (2018)

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Ruthenium-based metal organic framework (Ru-MOF)-derived novel Faraday-cage electrochemiluminescence biosensor for ultrasensitive detection of miRNA-141

Huili Shao et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

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Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy

Kaiyuan Ni et al.

NATURE COMMUNICATIONS (2018)

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A versatile MOF-based trap for heavy metal ion capture and dispersion

Yaguang Peng et al.

NATURE COMMUNICATIONS (2018)

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Composites based on heparin and MIL-101( Fe): the drug releasing depot for anticoagulant therapy and advanced medical nanofabrication

Vladimir V. Vinogradov et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Low-dose X-ray radiotherapy-radiodynamic therapy via nanoscale metal-organic frameworks enhances checkpoint blockade immunotherapy

Kuangda Lu et al.

NATURE BIOMEDICAL ENGINEERING (2018)

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Theranostic Mn-Porphyrin Metal-Organic Frameworks for Magnetic Resonance Imaging-Guided Nitric Oxide and Photothermal Synergistic Therapy

Hui Zhang et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Minimum information reporting in bio-nano experimental literature

Matthew Faria et al.

NATURE NANOTECHNOLOGY (2018)

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How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation

John P. A. Ioannidis et al.

NATURE BIOMEDICAL ENGINEERING (2018)

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Metal-Organic Frameworks for the Development of Biosensors: A Current Overview

Sergio Carrasco

BIOSENSORS-BASEL (2018)

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Stimuli-Responsive Nucleic Acid-Based Polyacrylamide Hydrogel-Coated Metal-Organic Framework Nanoparticles for Controlled Drug Release

Wei-Hai Chen et al.

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Porphyrinic Metal-Organic Frameworks Coated Gold Nanorods as a Versatile Nanoplatform for Combined Photodynamic/Photothermal/Chemotherapy of Tumor

Jin-Yue Zeng et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

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A Cooperative Copper Metal-Organic Framework-Hydrogel System Improves Wound Healing in Diabetes

Jisheng Xiao et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

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Osteogenic activity and antibacterial effect of porous titanium modified with metal-organic framework films

Junyu Chen et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2017)

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To heat or not to heat: Challenges with clinical translation of thermosensitive liposomes

Yannan Dou et al.

JOURNAL OF CONTROLLED RELEASE (2017)

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Attenuation of Antioxidant Capacity in Human Breast Cancer Cells by Carbon Monoxide through Inhibition of Cystathionine β-Synthase Activity: Implications in Chemotherapeutic Drug Sensitivity

Brian Kawahara et al.

JOURNAL OF MEDICINAL CHEMISTRY (2017)

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Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized Polymeric Nanocarriers

Yoanna Tsvetkova et al.

NANO LETTERS (2017)

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One-pot synthesis of multifunctional nanoscale metal-organic frameworks as an effective antibacterial agent against multidrug-resistant Staphylococcus aureus

Angshuman Ray Chowdhuri et al.

NANOTECHNOLOGY (2017)

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Editorial Material Multidisciplinary Sciences

Look beyond technology in cancer care

Richard Sullivan et al.

NATURE (2017)

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How much do clinical trials cost?

Linda Martin et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

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Water harvesting from air with metal-organic frameworks powered by natural sunlight

Hyunho Kim et al.

SCIENCE (2017)

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Integration of Biomolecules with Metal-Organic Frameworks

Jia Zhuang et al.

SMALL (2017)

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High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks

Xizhen Lian et al.

NATURE COMMUNICATIONS (2017)

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Exosome-Coated Metal-Organic Framework Nanoparticles: An Efficient Drug Delivery Platform

Bernhard Illes et al.

CHEMISTRY OF MATERIALS (2017)

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Cancer cell membrane-coated biomimetic platform for tumor targeted photodynamic therapy and hypoxia-amplified bioreductive therapy

Shi-Ying Li et al.

BIOMATERIALS (2017)

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Cancer Cell Membrane Camouflaged Cascade Bioreactor for Cancer Targeted Starvation and Photodynamic Therapy

Shi-Ying Li et al.

ACS NANO (2017)

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Controlled Release of Naringin in Metal-Organic Framework-Loaded Mineralized Collagen Coating to Simultaneously Enhance Osseointegration and Antibacterial Activity

Mengfei Yu et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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An updated roadmap for the integration of metal-organic frameworks with electronic devices and chemical sensors

Ivo Stassen et al.

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Metal-Organic Frameworks at the Biointerface: Synthetic Strategies and Applications

Christian Doonan et al.

ACCOUNTS OF CHEMICAL RESEARCH (2017)

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Infrared laser writing of MOFs

K. Hirai et al.

CHEMICAL COMMUNICATIONS (2017)

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Personalized medicine and follow-up of therapeutic delivery through exploitation of quantum dot toxicity

Bella B. Manshian et al.

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In Vivo Targeting and Positron Emission Tomography Imaging of Tumor with Intrinsically Radioactive Metal-Organic Frameworks Nanomaterials

Daiqin Chen et al.

ACS NANO (2017)

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Positioning metal-organic framework nanoparticles within the context of drug delivery - A comparison with mesoporous silica nanoparticles and dendrimers

Stefan Wuttke et al.

BIOMATERIALS (2017)

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Challenges and strategies in anti-cancer nanomedicine development: An industry perspective

Jennifer I. Hare et al.

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Scalable synthesis and post-modification of a mesoporous metal-organic framework called NU-1000

Timothy C. Wang et al.

NATURE PROTOCOLS (2016)

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Gasotransmitters in cancer: from pathophysiology to experimental therapy

Csaba Szabo

NATURE REVIEWS DRUG DISCOVERY (2016)

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Radioactive Barium Ion Trap Based on Metal-Organic Framework for Efficient and Irreversible Removal of Barium from Nuclear Wastewater

Yaguang Peng et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

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Metal-Organic-Framework-Based Vaccine Platforms for Enhanced Systemic Immune and Memory Response

Yan Zhang et al.

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An O2 Self-Sufficient Biomimetic Nanoplatform for Highly Specific and Efficient Photodynamic Therapy

Hong Cheng et al.

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Folate-targeted pH-responsive calcium zoledronate nanoscale metal-organic frameworks: Turning a bone antiresorptive agent into an anticancer therapeutic

Kin Man Au et al.

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Nanoscale metal-organic frameworks for combined photodynamic & radiation therapy in cancer treatment

Jingjing Liu et al.

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Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers

Andreas Zimpel et al.

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Nanostructured metal-organic frameworks and their bio-related applications

M. Gimenez-Marques et al.

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Exploration of MOF nanoparticle sizes using various physical characterization methods - is what you measure what you get?

Patrick Hirschle et al.

CRYSTENGCOMM (2016)

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Gaseous nitric oxide to treat antibiotic resistant bacterial and fungal lung infections in patients with cystic fibrosis: a phase I clinical study

Caroline Deppisch et al.

INFECTION (2016)

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Role of nanoparticle size, shape and surface chemistry in oral drug delivery

Amrita Banerjee et al.

JOURNAL OF CONTROLLED RELEASE (2016)

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Nanoscale Metal-Organic Frameworks for Ratiometric Oxygen Sensing in Live Cells

Ruoyu Xu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

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One-pot Synthesis of Metal Organic Frameworks with Encapsulated Target Molecules and Their Applications for Controlled Drug Delivery

Haoquan Zheng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

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New Insulin Delivery Recommendations

Anders H. Frid et al.

MAYO CLINIC PROCEEDINGS (2016)

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Tuning the nitric oxide release from CPO-27 MOFs

Damiano Cattaneo et al.

RSC ADVANCES (2016)

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Covalent organic frameworks: a materials platform for structural and functional designs

Ning Huang et al.

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Chemical, thermal and mechanical stabilities of metal-organic frameworks

Ashlee J. Howarth et al.

NATURE REVIEWS MATERIALS (2016)

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Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity

Hiroshi Maeda

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MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells

Stefan Wuttke et al.

CHEMICAL COMMUNICATIONS (2015)

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Multifunctional metal-organic frameworks: from academia to industrial applications

Patricia Silva et al.

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Methane storage in flexible metal-organic frameworks with intrinsic thermal management

Jarad A. Mason et al.

NATURE (2015)

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Principles of nanoparticle design for overcoming biological barriers to drug delivery

Elvin Blanco et al.

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Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules

Kang Liang et al.

NATURE COMMUNICATIONS (2015)

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Heterogeneous Nano Metal-Organic Framework Fluorescence Probe for Highly Selective and Sensitive Detection of Hydrogen Sulfide in Living Cells

Yu Ma et al.

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Zeolites with Continuously Tuneable Porosity

Paul S. Wheatley et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

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An overview of clinical and commercial impact of drug delivery systems

Aaron C. Anselmo et al.

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Approaches to Uremia

Timothy W. Meyer et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)

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Passive versus Active Tumor Targeting Using RGD- and NGR-Modified Polymeric Nanomedicines

Sijumon Kunjachan et al.

NANO LETTERS (2014)

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Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

Samir Mitragotri et al.

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Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

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NATURE REVIEWS DRUG DISCOVERY (2014)

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Nanoparticles for Imaging: Top or Flop?

Fabian Kiessling et al.

RADIOLOGY (2014)

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Metal-organic framework nanosheets as building blocks for molecular sieving membranes

Yuan Peng et al.

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Silver Sulfadiazine Nanosystems for Burn Therapy

Meenakshi Venkataraman et al.

AAPS PHARMSCITECH (2013)

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Stimuli-responsive nanocarriers for drug delivery

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Key roles of adjuvants in modern vaccines

Steven G. Reed et al.

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Antimicrobial activity of metals: mechanisms, molecular targets and applications

Joseph A. Lemire et al.

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The Chemistry and Applications of Metal-Organic Frameworks

Hiroyasu Furukawa et al.

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Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size

Qiu Li Loh et al.

TISSUE ENGINEERING PART B-REVIEWS (2013)

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The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

Alexandre Albanese et al.

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 14 (2012)

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Metal-Organic Frameworks in Biomedicine

Patricia Horcajada et al.

CHEMICAL REVIEWS (2012)

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Metal-organic frameworks for the storage and delivery of biologically active hydrogen sulfide

Phoebe K. Allan et al.

DALTON TRANSACTIONS (2012)

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Metal Organic Frameworks as Nitric Oxide Catalysts

Jacqueline L. Harding et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

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Hyperammonemia in review: pathophysiology, diagnosis, and treatment

Ari Auron et al.

PEDIATRIC NEPHROLOGY (2012)

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Large-Pore Apertures in a Series of Metal-Organic Frameworks

Hexiang Deng et al.

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Lipid-coated nanoscale coordination polymers for targeted delivery of antifolates to cancer cells

Rachel C. Huxford et al.

CHEMICAL SCIENCE (2012)

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Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme

Klaus Maier-Hauff et al.

JOURNAL OF NEURO-ONCOLOGY (2011)

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BioMOFs: Metal-Organic Frameworks for Biological and Medical Applications

Alistair C. McKinlay et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

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Porous metal-organic-framework nanoscale carriers as a potential platform for drug delivery and imaging

Patricia Horcajada et al.

NATURE MATERIALS (2010)

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Ultrahigh Porosity in Metal-Organic Frameworks

Hiroyasu Furukawa et al.

SCIENCE (2010)

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Control of Pore Size and Functionality in Isoreticular Zeolitic Imidazolate Frameworks and their Carbon Dioxide Selective Capture Properties

Rahul Banerjee et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

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Cation-Triggered Drug Release from a Porous Zinc-Adeninate Metal-Organic Framework

Jihyun An et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

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Targeted delivery of nanoparticles for the treatment of lung diseases

Shirzad Azarmi et al.

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The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance

Chris E. Cooper et al.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2008)

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Exceptional behavior over the whole adsorption-storage-delivery cycle for NO in porous metal organic frameworks

Alistair C. McKinlay et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

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The use of hyperbaric oxygen therapy to treat chronic wounds: A review

Jennifer A. Thackham et al.

WOUND REPAIR AND REGENERATION (2008)

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Exploiting lymphatic transport and complement activation in nanoparticle vaccines

Sai T. Reddy et al.

NATURE BIOTECHNOLOGY (2007)

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High-capacity hydrogen and nitric oxide adsorption and storage in a metal-organic framework

Bo Xiao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

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Metal-organic frameworks as efficient materials for drug delivery

Patricia Horcajada et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)

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PEGylation, successful approach to drug delivery

FM Veronese et al.

DRUG DISCOVERY TODAY (2005)

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Proceedings of the Hydrogen Sulfide Health Research and Risk Assessment Symposium, October 31-November 2, 2000

GM Woodall et al.

INHALATION TOXICOLOGY (2005)

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Can needle-free administration of vaccines become the norm in global immunization?

Myron M. Levine

NATURE MEDICINE (2003)

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Ordered porous materials for emerging applications

ME Davis

NATURE (2002)

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