4.5 Article

Oriented polyaniline/poly-l-lactic acid/gelatin nanofiber scaffolds promote outgrowth of spiral ganglion neurons

Related references

Note: Only part of the references are listed.
Article Materials Science, Biomaterials

Conductive Polyaniline Particles Regulating In Vitro Hydrolytic Degradation and Erosion of Hydroxyapatite/Poly(lactide-co-glycolide) Porous Scaffolds for Bone Tissue Engineering

Huanhuan Yan et al.

Summary: Injectable conductive porous scaffolds were fabricated by incorporating camphor sulfonic acid-doped polyaniline (PANI) into hydroxyapatite/poly-(lactide-co-glycolide) (HA/PLGA) scaffolds. These scaffolds exhibited excellent electroactivity, conductivity, hydrophilicity, antibacterial properties, and biocompatibility. Controlling the degradation behavior through PANI content regulation could promote bone ingrowth and restoration in conductive porous scaffolds.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2023)

Article Biochemical Research Methods

Bio-inspired engineering of a perfusion culture platform for guided three-dimensional nerve cell growth and differentiation

Zihou Wei et al.

Summary: This paper presents a bio-inspired design method for constructing a perfusion culture platform for guided nerve cell growth and differentiation in collagen. The use of a biomimetic porous structure and micro-capillary effect allows for the self-assembly of cell encapsulated collagen into the structure. The results show that the proposed platform has the potential for application in the study of nerve regeneration and drug screening.

LAB ON A CHIP (2022)

Review Biochemistry & Molecular Biology

Advances in Polyaniline for Biomedical Applications

Cristina Della Pina et al.

Summary: Polyaniline (PANI) is a promising material in the biomedical field due to its conductivity, biocompatibility, and low toxicity. However, its low solubility and processability pose challenges for practical applications. Different methods have been developed to overcome these limitations. This review highlights recent advances in PANI applications in biomedical fields and provides insights into the synthesis of more innovative materials in the future.

CURRENT MEDICINAL CHEMISTRY (2022)

Article Chemistry, Multidisciplinary

High Capacitive Antimonene/CNT/PANI Free-Standing Electrodes for Flexible Supercapacitor Engaged with Self-Healing Function

Yue Jiang et al.

Summary: In this study, antimonene nanosheets were introduced into the carbon nanotube framework for polyaniline electrodeposition, which resulted in the continuous and uniform growth of polyaniline. The resulting antimonene/carbon nanotube/polyaniline electrode exhibited high specific capacitance and excellent cycling stability in flexible supercapacitors. Additionally, the use of self-healable polyurethane enabled the practical self-healing function of the supercapacitor device.

SMALL (2022)

Article Neurosciences

SARS-CoV-2 Infection in the Central and Peripheral Nervous System-Associated Morbidities and Their Potential Mechanism

Mohan Kumar Muthu Karuppan et al.

Summary: The recent outbreak of COVID-19 caused by SARS-CoV-2 is a defining global health crisis, with evidence suggesting neurological issues may arise from the virus invading the CNS and PNS. The most critical symptom seems to be sudden loss of breathing in some patients, indicating potential dysfunction in brainstem regulatory centers. Further research is needed to confirm the virus's role in neurodegeneration.

MOLECULAR NEUROBIOLOGY (2021)

Review Neurosciences

Autophagy Regulates the Survival of Hair Cells and Spiral Ganglion Neurons in Cases of Noise, Ototoxic Drug, and Age-Induced Sensorineural Hearing Loss

Lingna Guo et al.

Summary: Inner ear hair cells and spiral ganglion neurons are crucial components of the auditory system, but they are susceptible to genetic defects, noise exposure, ototoxic drugs, and aging. Efforts to combat hearing loss have included cochlear implants, hair cell regeneration, gene therapy, and antioxidant drugs. Understanding the role of autophagy in sensorineural hearing loss and identifying potential autophagy-related targets could lead to new treatments for hearing loss.

FRONTIERS IN CELLULAR NEUROSCIENCE (2021)

Review Engineering, Biomedical

Anisotropic scaffolds for peripheral nerve and spinal cord regeneration

Wen Xue et al.

Summary: Using tissue engineering as an alternative approach, scaffolds with anisotropic structures play a crucial role in guiding neural outgrowth and reconnection for long-gap peripheral nerve and spinal cord injuries. Recent advances in fabrication techniques, such as anisotropic surface patterns and 3D hydrogel scaffolds, show promising in vitro and in vivo effects in orienting axonal and glial cell growth. Challenges and prospects of anisotropic architectures in tissue engineering are also discussed.

BIOACTIVE MATERIALS (2021)

Review Biochemistry & Molecular Biology

The role of basement membranes in cardiac biology and disease

Erin Boland et al.

Summary: Basement membranes play a crucial role in the heart by providing structural support and influencing cell behavior, yet their role in cardiac biology remains under-researched. Understanding the interplay between basement membrane defects and their consequences in cardiac disease is an important area for future research.

BIOSCIENCE REPORTS (2021)

Article Materials Science, Biomaterials

Engineering 2D approaches fibrous platform incorporating turmeric and polyaniline nanoparticles to predict the expression of βIII-Tubulin and TREK-1 through qRT-PCR to detect neuronal differentiation of PC12 cells

Sita Shrestha et al.

Summary: The development of a PCL nanofibrous substrate consisting of turmeric and polyaniline nanoparticles showed promising results in promoting nerve cell activities. The optimal cellular microenvironment accelerated cell proliferation and differentiation, offering potential biomaterials for in vivo peripheral nerve repair.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Review Engineering, Biomedical

Electrical Stimulation and Conductive Polymers as a Powerful Toolbox for Tailoring Cell Behaviour in vitro

Igor Rocha et al.

Summary: Electrical stimulation is a widely used method for guiding nerve cell behavior in vitro systems, and understanding how electrochemical stimulus can be tuned for desired cell response is crucial. The physicochemical properties of materials used for cell culture play a significant role in influencing cell behavior under electrical stimulation. Conductive polymers are commonly used in cell culture arrays under ES, but improvements in cell compatibility and bioactivity require tailored chemical properties on material surfaces and consideration of material structure.

FRONTIERS IN MEDICAL TECHNOLOGY (2021)

Article Materials Science, Biomaterials

Designing aromatic N-cadherin mimetic short-peptide-based bioactive scaffolds for controlling cellular behaviour

Harsimran Kaur et al.

Summary: The development of biomaterials that mimic cellular interactions is crucial for successful tissue engineering. By incorporating bioactive motifs, such as the N-cadherin mimetic peptides in designer scaffolds, it is possible to create materials that support cell adhesion, proliferation, and mimic the properties of the native extracellular matrix. The study demonstrates the importance of bioactive motifs in controlling cellular behavior and provides a promising avenue for next-generation tissue engineering applications.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Article Engineering, Biomedical

Intact polyaniline coating as a conductive guidance is beneficial to repairing sciatic nerve injury

Guowu Wang et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2020)

Article Engineering, Biomedical

Decellularized equine carotid artery layers as matrix for regenerated neurites of spiral ganglion neurons

Suheda Yilmaz-Bayraktar et al.

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS (2020)

Article Nanoscience & Nanotechnology

Fabrication of Nanocomposites Complexed with Gold Nanoparticles on Polyaniline and Application to Their Nerve Regeneration

Hye Jin Kim et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Review Developmental Biology

Development of the cochlea

Elizabeth Carroll Driver et al.

DEVELOPMENT (2020)

Article Engineering, Biomedical

3D printing collagen/chitosan scaffold ameliorated axon regeneration and neurological recovery after spinal cord injury

Yan Sun et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2019)

Review Biochemistry & Molecular Biology

Gene therapy for hearing loss

Ryotaro Omichi et al.

HUMAN MOLECULAR GENETICS (2019)

Article Nanoscience & Nanotechnology

Biocompatible and Biodegradable 3D Double-Network Fibrous Scaffold for Excellent Cell Growth

Zhanrong Li et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2019)

Article Materials Science, Multidisciplinary

Polyglycerol sebacate/chitosan/gelatin nano-composite scaffolds for engineering neural construct

Sanaz Saravani et al.

MATERIALS CHEMISTRY AND PHYSICS (2019)

Article Biophysics

Functionalized silk fibroin film scaffold using β-Carotene for cornea endothelial cell regeneration

Do Kyung Kim et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2018)

Article Materials Science, Biomaterials

Preparation, characterization and application research of a sustained dexamethasone releasing electrode coating for cochlear implantation

Muqing Xu et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2018)

Article Anatomy & Morphology

Vascularization Strategies for Peripheral Nerve Tissue Engineering

Papon Muangsanit et al.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2018)