Green Synthesis and Biosafety Assessment of MXene

The rise of MXene-based materials with fascinating physical and chemical properties has attracted wide attention in the field of biomedicine, because it can be exploited to regulate a variety of biological processes. The biomedical applications of MXene are still in its infancy, nevertheless, the comprehensive evaluation of MXene's biosafety is desperately needed. In this review, the composition and the synthetic methods of MXene materials are first introduced from the view of biosafety. The evaluation of the interaction between MXene and cells, as well as the safety of different forms of MXene applied in vivo are then discussed. This review provides a basic understanding of MXene biosafety and may bring new inspirations to the future applications of MXene-based materials in biomedicine. In this review, the synthetic methods of MXene are introduced first from the view of biosafety. The interaction between MXene and cells, as well as the safety of MXene applied in vivo are then discussed. This review article thinks environmentally friendly, fluorine-free, and simple production of MXene with modified surface and degradation properties has great potential for biomedicine.image

Automated summary

This review introduces the biosafety of MXene materials and discusses their interactions with cells and safety in vivo. Comprehensive evaluation of MXene's biosafety is crucial for its future applications in biomedicine.