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Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth
Sung Eun Kim et al.
NATURE NANOTECHNOLOGY (2016)
Survey of food-grade silica dioxide nanomaterial occurrence, characterization, human gut impacts and fate across its lifecycle
Yu Yang et al.
SCIENCE OF THE TOTAL ENVIRONMENT (2016)
Genotoxic and cytotoxic effects of ZnO nanoparticles for Dunaliella tertiolecta and comparison with SiO2 and TiO2 effects at population growth inhibition levels
S. Schiavo et al.
SCIENCE OF THE TOTAL ENVIRONMENT (2016)
Protocells: Modular Mesoporous Silica Nanoparticle-Supported Lipid Bilayers for Drug Delivery
Kimberly S. Butler et al.
SMALL (2016)
Silica Nanoparticles Target a Wnt Signal Transducer for Degradation and Impair Embryonic Development in Zebrafish
Hongyang Yi et al.
THERANOSTICS (2016)
Silica nanoparticle-generated ROS as a predictor of cellular toxicity: mechanistic insights and safety by design
Sean E. Lehman et al.
ENVIRONMENTAL SCIENCE-NANO (2016)
Gated supramolecular chemistry in hybrid mesoporous silica nanoarchitectures: controlled delivery and molecular transport in response to chemical, physical and biological stimuli
Sebastian Alberti et al.
CHEMICAL COMMUNICATIONS (2015)
Multidisciplinary screening of toxicity induced by silica nanoparticles during sea urchin development
Chiara Gambardella et al.
CHEMOSPHERE (2015)
Ecological risk assessment of silicon dioxide nanoparticles in a freshwater fish Labeo rohita: Hematology, ionoregulation and gill Na+/K+ ATPase activity
K. Krishna Priya et al.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2015)
Silica nanoparticles: Preparation, characterization and in vitro/in vivo biodistribution studies
B. I. Tamba et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Silica Nanoparticles Induce Oxidative Stress and Autophagy but Not Apoptosis in the MRC-5 Cell Line
Sorina Nicoleta Petrache Voicu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling
Caixia Guo et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2015)
In vivo genotoxic effects of four different nano-sizes forms of silica nanoparticles in Drosophila melanogaster
Esref Demir et al.
JOURNAL OF HAZARDOUS MATERIALS (2015)
Biodistribution, excretion, and toxicity of mesoporous silica nanoparticles after oral administration depend on their shape
Linlin Li et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)
Toxicity of silica nanoparticles depends on size, dose, and cell type
In-Yong Kim et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)
Mesoporous silica nanoparticles in drug delivery and biomedical applications
Ying Wang et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)
Smart multifunctional drug delivery towards anticancer therapy harmonized in mesoporous nanoparticles
Seonmi Baek et al.
NANOSCALE (2015)
Endoplasmic reticulum stress and oxidative stress are involved in ZnO nanoparticle-induced hepatotoxicity
Xia Yang et al.
TOXICOLOGY LETTERS (2015)
Fate of fluorescent core-shell silica nanoparticles during simulated secondary wastewater treatment
Lila Otero-Gonzalez et al.
WATER RESEARCH (2015)
Heteroagglomeration of Oxide Nanoparticles with Algal Cells: Effects of Particle Type, Ionic Strength and pH
Si Ma et al.
ENVIRONMENTAL SCIENCE & TECHNOLOGY (2015)
Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC
Koumei Shirasuna et al.
NANOTOXICOLOGY (2015)
Acute exposure to silica nanoparticles aggravate airway inflammation: different effects according to surface characteristics
Hye Jung Park et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2015)
MSN Anti-Cancer Nanomedicines: Chemotherapy Enhancement, Overcoming of Drug Resistance, and Metastasis Inhibition
Qianjun He et al.
ADVANCED MATERIALS (2014)
Multifunctional Core-Shell Silica Nanoparticles for Highly Sensitive 19F Magnetic Resonance Imaging
Hisashi Matsushita et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Cytotoxicity evaluation of silica nanoparticles using fish cell lines
Nguyen T. K. Vo et al.
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2014)
Comparison of Nanoparticle Exposures Between Fumed and Sol-gel Nano-silica Manufacturing Facilities
Sewan Oh et al.
INDUSTRIAL HEALTH (2014)
Assessment of Nanoparticle Exposure in Nanosilica Handling Process: Including Characteristics of Nanoparticles Leaking from a Vacuum Cleaner
Boowook Kim et al.
INDUSTRIAL HEALTH (2014)
Amorphous silica nanoparticles impair vascular homeostasis and induce systemic inflammation
Abderrahim Nemmar et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2014)
Evaluation of the toxicity of food additive silica nanoparticles on gastrointestinal cells
Yi-Xin Yang et al.
JOURNAL OF APPLIED TOXICOLOGY (2014)
Silica nanoparticles induce autophagy and autophagic cell death in HepG2 cells triggered by reactive oxygen species
Yongbo Yu et al.
JOURNAL OF HAZARDOUS MATERIALS (2014)
Nanometer-long Ge-imogolite nanotubes cause sustained lung inflammation and fibrosis in rats
Sybille van den Brule et al.
PARTICLE AND FIBRE TOXICOLOGY (2014)
Silica nanoparticles enhance autophagic activity, disturb endothelial cell homeostasis and impair angiogenesis
Junchao Duan et al.
PARTICLE AND FIBRE TOXICOLOGY (2014)
The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles
Virginie Rabolli et al.
PARTICLE AND FIBRE TOXICOLOGY (2014)
Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe
Evan Phillips et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Inflammation and gene expression in the rat lung after instillation of silica nanoparticles: Effect of size, dispersion medium and particle surface charge
David M. Brown et al.
TOXICOLOGY LETTERS (2014)
Uptake of silica nanoparticles: Neurotoxicity and Alzheimer-like pathology in human SK-N-SH and mouse neuro2a neuroblastoma cells
Xifei Yang et al.
TOXICOLOGY LETTERS (2014)
Toxic response of HIPCO single-walled carbon nanotubes in mice and RAW264.7 macrophage cells
Eun-Jung Park et al.
TOXICOLOGY LETTERS (2014)
Unambiguous observation of shape effects on cellular fate of nanoparticles
Zhiqin Chu et al.
SCIENTIFIC REPORTS (2014)
Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials
Fernando Torres Andon et al.
ACCOUNTS OF CHEMICAL RESEARCH (2013)
Two-Wave Nanotherapy To Target the Stroma and Optimize Gemcitabine Delivery To a Human Pancreatic Cancer Model in Mice
Huan Meng et al.
ACS NANO (2013)
Artesunate inhibits the growth of gastric cancer cells through the mechanism of promoting oncosis both in vitro and in vivo
Xiang Zhou et al.
ANTI-CANCER DRUGS (2013)
Cellular internalization and stress response of ingested amorphous silica nanoparticles in the midgut of Drosophila melanogaster
Ashutosh Pandey et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes
Changhui Fu et al.
BIOMATERIALS (2013)
Cardiovascular toxicity evaluation of silica nanoparticles in endothelial cells and zebrafish model
Junchao Duan et al.
BIOMATERIALS (2013)
Nonporous silica nanoparticles for nanomedicine application
Li Tang et al.
NANO TODAY (2013)
Risk assessment of amorphous silicon dioxide nanoparticles in a glass cleaner formulation
Karin Michel et al.
NANOTOXICOLOGY (2013)
An Assessment of the Impact of SiO2 Nanoparticles of Different Sizes on the Rest/Wake Behavior and the Developmental Profile of Zebrafish Larvae
Ji-Yang Xue et al.
SMALL (2013)
Uptake Kinetics and Nanotoxicity of Silica Nanoparticles Are Cell Type Dependent
Julia Blechinger et al.
SMALL (2013)
Size-dependent cellular uptake efficiency, mechanism, and cytotoxicity of silica nanoparticles toward HeLa cells
Jie Zhu et al.
TALANTA (2013)
In Vivo Targeting and Imaging of Tumor Vasculature with Radiolabeled, Antibody-Conjugated Nanographene
Hao Hong et al.
ACS NANO (2012)
Influence of Geometry, Porosity, and Surface Characteristics of Silica Nanoparticles on Acute Toxicity: Their Vasculature Effect and Tolerance Threshold
Tian Yu et al.
ACS NANO (2012)
Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery
Fangqiong Tang et al.
ADVANCED MATERIALS (2012)
Distribution and histologic effects of intravenously administered amorphous nanosilica particles in the testes of mice
Yuki Morishita et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
Liming Sun et al.
CELL (2012)
Mitochondria: In Sickness and in Health
Jodi Nunnari et al.
CELL (2012)
Oncosis: An important non-apoptotic mode of cell death
Priya Weerasinghe et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2012)
In vivo biodistribution and pharmacokinetics of silica nanoparticles as a function of geometry, porosity and surface characteristics
Tian Yu et al.
JOURNAL OF CONTROLLED RELEASE (2012)
Application of mesoporous silicon dioxide and silicate in oral amorphous drug delivery systems
Ken K. Qian et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
Processing Pathway Dependence of Amorphous Silica Nanoparticle Toxicity: Colloidal vs Pyrolytic
Haiyuan Zhang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Mesoporous Silica Nanoparticles for Increasing the Oral Bioavailability and Permeation of Poorly Water Soluble Drugs
Yanzhuo Zhang et al.
MOLECULAR PHARMACEUTICS (2012)
Nanoparticles in targeted cancer therapy: mesoporous silica nanoparticles entering preclinical development stage
Jessica M. Rosenholm et al.
NANOMEDICINE (2012)
Bioactive silica-based nanoparticles stimulate bone-forming osteoblasts, suppress bone-resorbing osteoclasts, and enhance bone mineral density in vivo
George R. Beck et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2012)
Adsorption and release of biocides with mesoporous silica nanoparticles
Amirali Popat et al.
NANOSCALE (2012)
Assessment of side-effects by Ludox TMA silica nanoparticles following a dietary exposure on the bumblebee Bombus terrestris
Veerle Mommaerts et al.
NANOTOXICOLOGY (2012)
Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity
Stephan T. Stern et al.
PARTICLE AND FIBRE TOXICOLOGY (2012)
Bax regulates primary necrosis through mitochondrial dynamics
Russell S. Whelan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The toxicological mode of action and the safety of synthetic amorphous silica-A nanostructured material
Claudia Fruijtier-Poelloth
TOXICOLOGY (2012)
Apoptosis induction by silica nanoparticles mediated through reactive oxygen species in human liver cell line HepG2
Javed Ahmad et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)
Nanotechnology Regulation: A Study in Claims Making
Timothy F. Malloy
ACS NANO (2011)
Influence of Scaffold Size on Bactericidal Activity of Nitric Oxide-Releasing Silica Nanoparticles
Alexis W. Carpenter et al.
ACS NANO (2011)
Neurotoxicity of Silica Nanoparticles: Brain Localization and Dopaminergic Neurons Damage Pathways
Jie Wu et al.
ACS NANO (2011)
The Shape Effect of Mesoporous Silica Nanoparticles on Biodistribution, Clearance, and Biocompatibility in Vivo
Xinglu Huang et al.
ACS NANO (2011)
Interaction of Mesoporous Silica Nanoparticles with Human Red Blood Cell Membranes: Size and Surface Effects
Yannan Zhao et al.
ACS NANO (2011)
PEGylated Inorganic Nanoparticles
Ajay S. Karakoti et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Cytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cells
Alexander T. Bauer et al.
BIOMATERIALS (2011)
The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis
Soyoung Lee et al.
BIOMATERIALS (2011)
Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles
Chao Wang et al.
BIOMATERIALS (2011)
Hollow chitosan-silica nanospheres as pH-sensitive targeted delivery carriers in breast cancer therapy
Ziwei Deng et al.
BIOMATERIALS (2011)
Presence and risks of nanosilica in food products
Susan Dekkers et al.
NANOTOXICOLOGY (2011)
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
Joshua M. Baughman et al.
NATURE (2011)
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
Diego De Stefani et al.
NATURE (2011)
Silica and titanium dioxide nanoparticles cause pregnancy complications in mice
Kohei Yamashita et al.
NATURE NANOTECHNOLOGY (2011)
Interaction of Spherical Silica Nanoparticles with Neuronal Cells: Size-Dependent Toxicity and Perturbation of Calcium Homeostasis
Paolo Ariano et al.
SMALL (2011)
Oxidative mechanisms contribute to nanosize silican dioxide-induced developmental neurotoxicity in PC12 cells
Fen Wang et al.
TOXICOLOGY IN VITRO (2011)
Endoplasmic-Reticulum Calcium Depletion and Disease
Djalila Mekahli et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
Functional Assessment of Metal Oxide Nanoparticle Toxicity in Immune Cells
Melissa A. Maurer-Jones et al.
ACS NANO (2010)
Molecularly imprinted layer-coated silica nanoparticles for selective solid-phase extraction of bisphenol A from chemical cleansing and cosmetics samples
Rong Zhu et al.
ANALYTICA CHIMICA ACTA (2010)
In vitro effects of suspensions of selected nanoparticles (C60 fullerene, TiO2, SiO2) on Mytilus hemocytes
Laura Canesi et al.
AQUATIC TOXICOLOGY (2010)
ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy
Liang Qin et al.
AUTOPHAGY (2010)
Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles
Jeffrey S. Souris et al.
BIOMATERIALS (2010)
Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-κB pathways
Xin Liu et al.
BIOMATERIALS (2010)
Methods in Mammalian Autophagy Research
Noboru Mizushima et al.
CELL (2010)
Impacts of Mesoporous Silica Nanoparticle Size, Pore Ordering, and Pore Integrity on Hemolytic Activity
Yu-Shen Lin et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
A complementary definition of nanomaterial
Wolfgang G. Kreyling et al.
NANO TODAY (2010)
Mitochondria and cell death: outer membrane permeabilization and beyond
Stephen W. G. Tait et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
The nanosilica hazard: another variable entity
Dorota Napierska et al.
PARTICLE AND FIBRE TOXICOLOGY (2010)
Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma
Ken Donaldson et al.
PARTICLE AND FIBRE TOXICOLOGY (2010)
Fate of Silica Nanoparticles in Simulated Primary Wastewater Treatment
Helen P. Jarvie et al.
ENVIRONMENTAL SCIENCE & TECHNOLOGY (2009)
Genotoxicity and ecotoxicity assays using the freshwater crustacean Daphnia magna and the larva of the aquatic midge Chironomus riparius to screen the ecological risks of nanoparticle exposure
Si-Won Lee et al.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2009)
Silica nanoparticles as hepatotoxicants
Hikaru Nishimori et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2009)
MECHANISMS OF DISEASE Cell Death
Richard S. Hotchkiss et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
In Caenorhabditis elegans Nanoparticle-Bio-Interactions Become Transparent: Silica-Nanoparticles Induce Reproductive Senescence
Adam Pluskota et al.
PLOS ONE (2009)
Size-Dependent Cytotoxicity of Monodisperse Silica Nanoparticles in Human Endothelial Cells
Dorota Napierska et al.
SMALL (2009)
Gold Nanoparticles of Diameter 1.4 nm Trigger Necrosis by Oxidative Stress and Mitochondrial Damage
Yu Pan et al.
SMALL (2009)
Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers
Igor I. Slowing et al.
ADVANCED DRUG DELIVERY REVIEWS (2008)
Autophagy as a second level protective process in conferring resistance to environmentally-induced oxidative stress
Michael N. Moore
AUTOPHAGY (2008)
Molecular mechanisms and pathophysiology of necrotic cell death
Nele Vanlangenakker et al.
CURRENT MOLECULAR MEDICINE (2008)
Silica binding and toxicity in alveolar macrophages
Raymond F. Hamilton et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Size-dependent toxicity of silica nano-particles to Chlorella kessleri
Kitao Fujiwara et al.
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING (2008)
Mesoporous silica nanospheres as highly efficient MRI contrast agents
Kathryn M. L. Taylor et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Origin and physiological roles of inflammation
Ruslan Medzhitov
NATURE (2008)
Stability of commercial metal oxide nanoparticles in water
Yang Zhang et al.
WATER RESEARCH (2008)
Morphogenetic activity of silica and bio-silica on the expression of genes controlling biomineralization using SaOS-2 cells
Werner E. G. Mueller et al.
CALCIFIED TISSUE INTERNATIONAL (2007)
A template route to the preparation of mesoporous amorphous calcium silicate with high in vitro bone-forming bioactivity
Xia Li et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2007)
Stimulating effect of silica-containing nanospheres on proliferation of osteoblast-like cells
Jie Feng et al.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2007)
Signal integration in the endoplasmic reticulum unfolded protein response
David Ron et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
The Bcl-2 apoptotic switch in cancer development and therapy
J. M. Adams et al.
ONCOGENE (2007)
Mitochondrial oxidative stress: Implications for cell death
Sten Orrenius et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2007)
Template synthesis of multifunctional nanotubes for controlled release
Sang Jun Son et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Toxic potential of materials at the nanolevel
A Nel et al.
SCIENCE (2006)
Apoptosis and necrosis in the liver: A tale of two deaths?
H Malhi et al.
HEPATOLOGY (2006)
Nanotoxicology:: An emerging discipline evolving from studies of ultrafine particles
G Oberdörster et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2005)
Apoptotic pathways: Ten minutes to dead
DR Green
CELL (2005)
Silica-coated nanocomposites of magnetic nanoparticles and quantum dots
DK Yi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
SJ Marciniak et al.
GENES & DEVELOPMENT (2004)
Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: A novel drug-carrier system for photodynamic therapy
I Roy et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis
B Fubini et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Induction and regulation of hepatocyte apoptosis by oxidative stress
MJ Czaja
ANTIOXIDANTS & REDOX SIGNALING (2002)
A new property of MCM-41:: Drug delivery system
M Vallet-Regi et al.
CHEMISTRY OF MATERIALS (2001)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
A Bertolotti et al.
NATURE CELL BIOLOGY (2000)