Electrochemical and spectroscopic detection of insulin using AgNPs-decorated organic derivative

Insulin is a crucial hormone that plays a vital role in regulating blood glucose levels in the body. The accurate detection of insulin is essential for the diagnosis and management of diabetes, a chronic disease that affects millions of people worldwide. In present work, we present an approach for the detection of insulin using a 4H- chromene derivative surface decorated with AgNPs. The method involves the use of cyclic voltammetry, linear sweep voltammetry, chronoamperometry, UV-visible and fluorescence spectroscopy, all of which are carried out in an aqueous medium. Our results demonstrate that the proposed method exhibits a low detection limit of 2 nM, high sensitivity (1.77 mu A nM-1 cm-2), and excellent reproducibility (3.21 %). The electrochemical and spectro-scopic measurements provide accurate and reliable detection of insulin in various concentrations. The method's property of detecting insulin in both liquid and solid state makes it a cost-effective and environment friendly alternative to conventional detection methods, with significant implications in the field of diabetes management.

Automated summary

This study presents a method for detecting insulin using a 4H-chromene derivative surface decorated with AgNPs. The method exhibits a low detection limit, high sensitivity, and excellent reproducibility, and can accurately detect insulin in both liquid and solid state. This cost-effective and environment friendly method has significant implications in the field of diabetes management.