☆ 4.4 Review

Proteomic analysis investigating kidney transplantation outcomes- a scoping review

BMC NEPHROLOGY (2023)

Related references

Note: Only part of the references are listed.

Review Biochemistry & Molecular Biology

Biomarker-Development Proteomics in Kidney Transplantation: An Updated Review

Vittorio Sirolli et al.

Summary: Kidney transplantation is the best treatment option for end-stage renal disease patients and requires careful monitoring of graft function. Routine clinical monitoring has limitations and can only detect graft damage at a later stage. Noninvasive biomarker molecules are needed for continuous monitoring after kidney transplantation to enable early diagnosis of graft dysfunction and improve clinical outcomes. Proteomic technologies have revolutionized medical research and have been studied as potential molecular markers for predicting graft outcomes in kidney transplantation. This article reviews the latest findings on proteomic studies in renal transplantation to better understand the potential of this new diagnostic approach.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Add to Collection

Review Immunology

Urinary Biomarkers for Kidney Allograft Injury

Paul H. Jin et al.

Summary: The current standard of serum creatinine and biopsy has limitations in monitoring allograft health. A biomarker that is sensitive and specific to early detection of allograft injuries is needed. Urine, which directly reflects intrarenal processes, is more accurate than peripheral blood analysis. Transcriptomic, metabolomic, genomic, and proteomic approaches can be used to identify urinary biomarkers for noninvasive detection of allograft injuries, and urine cell-free DNA can be used as a sensitive surrogate for renal allograft biopsy for rejection diagnosis.

TRANSPLANTATION (2022)

Add to Collection

Article Immunology

Urinary Retinol-Binding Protein 4 is Associated With Renal Function and Rapid Renal Function Decline in Kidney Transplant Recipients

Hee Jung Jeon et al.

Summary: Urinary RBP4 levels are associated with renal function and can be used to predict rapid renal function decline in kidney transplant recipients.

TRANSPLANTATION PROCEEDINGS (2022)

Add to Collection

Article Medicine, General & Internal

Two-Week Protocol Biopsy in Renal Allograft: Feasibility, Safety, and Outcomes

Manuel Lim et al.

Summary: This study evaluated the technical feasibility, procedure safety, and clinical outcomes of two-week protocol biopsy. The results showed that two-week protocol biopsy is technically feasible and safe, and it contributes to early detection of subclinical rejection. Platelet count and blood urea nitrogen should be carefully checked prior to the biopsy to predict major complications.

JOURNAL OF CLINICAL MEDICINE (2022)

Add to Collection

Review Urology & Nephrology

Extracellular vesicles in kidney disease

Cristina Grange et al.

Summary: Extracellular vesicles play significant roles in kidney physiology and pathology by facilitating cell-to-cell communication and modulating gene expression and fate of target cells. They have potential diagnostic, prognostic, and therapeutic applications in kidney diseases, including in the field of kidney regeneration and inflammation reduction. Stem cell-derived extracellular vesicles are considered as promising therapeutic agents, but standardized production strategies are still needed for their clinical application.

NATURE REVIEWS NEPHROLOGY (2022)

Add to Collection

Review Immunology

How to Deal With Kidney Retransplantation-Second, Third, Fourth, and Beyond

Junichiro Sageshima et al.

Summary: Kidney transplantation is the best health option for patients with end-stage kidney disease, but multiple transplants may be needed. Surgical approach and immunologic concerns are key, and other factors such as thrombosis and posttransplant events should also be considered.

TRANSPLANTATION (2022)

Add to Collection

Article Biology

Proteomics for Early Detection of Non-Muscle-Invasive Bladder Cancer: Clinically Useful Urine Protein Biomarkers

Jae-Hak Ahn et al.

Summary: Bladder cancer is the fourth most common cancer in men, with most cases being non-muscle-invasive. The high recurrence rate in non-muscle-invasive bladder cancer is a critical issue. Limited urine tests hinder the effective detection of superficial and small bladder tumors. Cystoscopy, although the gold standard for diagnosis, is associated with complications. Therefore, the development of urinary biomarkers is necessary for the detection of bladder cancer.

LIFE-BASEL (2022)

Add to Collection

Review Medicine, Research & Experimental

High-throughput proteomics: a methodological mini-review

Miao Cui et al.

Summary: Proteomics plays a vital role in biomedical research by providing new insights into complex biomedical problems. This mini-review summarizes existing and emerging high-throughput proteomics methodologies and discusses the importance of computational methods and statistical algorithms in maximizing the value of proteomic data. The advances in high-throughput proteomics not only enhance our understanding of disease mechanisms, but also offer potential applications in various fields such as basic research, oncology, precision medicine, and drug discovery.

LABORATORY INVESTIGATION (2022)

Add to Collection

Review Environmental Sciences

The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review

Krzysztof Ratajczyk et al.

Summary: Effective biomarkers for early diagnosis, prognostication, and monitoring in renal diseases are currently lacking. Urinary retinol-binding protein 4, as the most sensitive indicator of renal tubular damage, holds great promise as a universal biomarker for renal pathologies driven by tubular injury. This article summarises the existing data on the associations between urinary retinol-binding protein 4 and renal diseases and highlights its untapped potential in clinical use.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

Add to Collection

Article Immunology

Tofacitinib treatment modulates the levels of several inflammation-related plasma proteins in rheumatoid arthritis and baseline levels of soluble biomarkers associate with the treatment response

Atte Valli et al.

Summary: This study investigated the effects of tofacitinib treatment on the levels of inflammation-related soluble proteins in patients with rheumatoid arthritis. The results showed that tofacitinib decreased the levels of several proinflammatory plasma proteins, and the baseline levels of certain proteins were associated with the treatment response.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2022)

Add to Collection

Review Biochemistry & Molecular Biology

Proteomics for Biomarker Discovery for Diagnosis and Prognosis of Kidney Transplantation Rejection

Luis M. Ramalhete et al.

Summary: Renal transplantation is the preferred treatment for end-stage kidney disease, but the risk of graft rejection is a concern. Current diagnosis methods have limitations and routine clinical monitoring is not effective in detecting rejection processes in a timely manner. This highlights the urgent need for new biomarkers obtained through non-invasive procedures to predict rejection processes and enable personalized treatment for better graft survival and patient quality of life.

PROTEOMES (2022)

Add to Collection

Review Health Care Sciences & Services

Best practice guidance and reporting items for the development of scoping review protocols

Micah D. J. Peters et al.

Summary: This article aims to provide detailed guidance on developing a robust scoping review protocol and highlights the importance and definition of scoping reviews. Through outlining the methods and conclusions, the authors hope that readers will understand and implement the process of developing a scoping review protocol.

JBI EVIDENCE SYNTHESIS (2022)

Add to Collection

Review Urology & Nephrology

Management of patients with a failed kidney transplant: what should we do?

Marco Fiorentino et al.

Summary: The mortality rate for patients returning to dialysis after kidney transplant failure is significantly higher compared to those with functioning grafts. There is controversy surrounding the management of these patients, with a lack of clear clinical guidelines. Retransplantation is a feasible option that may help minimize morbidity and mortality risks associated with dialysis reinitiation.

CLINICAL KIDNEY JOURNAL (2021)

Add to Collection

Article Urology & Nephrology

Urinary vitronectin identifies patients with high levels of fibrosis in kidney grafts

Laura Carreras-Planella et al.

Summary: The study identified urinary vitronectin levels as a potential stand-alone biomarker for monitoring fibrotic changes in kidney transplant recipients non-invasively.

JOURNAL OF NEPHROLOGY (2021)

Add to Collection

Review Immunology

Emerging biomarkers of delayed graft function in kidney transplantation

Valeria Mezzolla et al.

Summary: Delayed Graft Function (DGF) is a common early complication in kidney transplantation, associated with poor graft outcomes, prolonged post-operative hospitalization, and higher rejection rates. The use of nonstandard kidneys from ECD and DCD donors is expected to increase the incidence of DGF, highlighting the importance of using omics technologies to discover new biomarkers.

TRANSPLANTATION REVIEWS (2021)

Add to Collection

Review Oncology

Proteomics as a Complementary Technique to Characterize Bladder Cancer

Ruben Lopez-Cortes et al.

Summary: This review highlights the contributions of proteomics to the molecular classification and histopathology study of bladder cancer. It also emphasizes the importance of proteomics in understanding the cellular and molecular changes as a consequence of bladder cancer therapy.

CANCERS (2021)

Add to Collection

Review Medicine, General & Internal

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J. Page et al.

Summary: The PRISMA statement was designed to help systematic reviewers transparently report the purpose, methods, and findings of their reviews. The updated PRISMA 2020 statement includes new reporting guidance, a 27-item checklist, an abstract checklist, and revised flow diagrams for reviews.

BMJ-BRITISH MEDICAL JOURNAL (2021)

Add to Collection

Article Surgery

The economic burden of kidney graft failure in the United States

Jesse Sussell et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2020)

Add to Collection

Article Transplantation

New Markers for Transplant Rejection

Hassan Argani

Experimental and Clinical Transplantation (2020)

Add to Collection

Article Biochemical Research Methods

Potential urinary extracellular vesicle protein biomarkers of chronic active antibody-mediated rejection in kidney transplant recipients

Hee-Yeon Jung et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2020)

Add to Collection

Review Biochemistry & Molecular Biology

Recent Advances on Biomarkers of Early and Late Kidney Graft Dysfunction

Marco Quaglia et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection

Article Urology & Nephrology

Urinary Protein Biomarker Panel for the Diagnosis of Antibody-Mediated Rejection in Kidney Transplant Recipients

Inge Mertens et al.

KIDNEY INTERNATIONAL REPORTS (2020)

Add to Collection

Article Urology & Nephrology

Extracellular Matrix Injury of Kidney Allografts in Antibody-Mediated Rejection: A Proteomics Study

Sergi Clotet-Freixas et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

Add to Collection

Article Cell Biology

The proteomic landscape of small urinary extracellular vesicles during kidney transplantation

Fabian Braun et al.

JOURNAL OF EXTRACELLULAR VESICLES (2020)

Add to Collection

Review Genetics & Heredity

Advances in Detection of Kidney Transplant Injury

Sanjeeva Herath et al.

MOLECULAR DIAGNOSIS & THERAPY (2019)

Add to Collection

Article Surgery

Progressive improvement in short, medium and long-term graft survival in kidney transplantation patients in Ireland - a retrospective study

Donal J Sexton et al.

TRANSPLANT INTERNATIONAL (2019)

Add to Collection

Article Immunology

Circulating microvesicle protein is associated with renal transplant outcome

Khalid Al-Nedawi et al.

TRANSPLANT IMMUNOLOGY (2019)

Add to Collection

Article Surgery

Urinary proteomics to diagnose chronic active antibody-mediated rejection in pediatric kidney transplantation - a pilot study

Nele Kirsten Kanzelmeyer et al.

TRANSPLANT INTERNATIONAL (2019)

Add to Collection

Article Immunology

Prediction of BK viremia by urine viral load in renal transplant patients: An analysis of BK viral load results in paired urine and plasma samples

Kathleen Madden et al.

TRANSPLANT INFECTIOUS DISEASE (2018)

Add to Collection

Article Medicine, General & Internal

PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation

Andrea C. Tricco et al.

ANNALS OF INTERNAL MEDICINE (2018)

Add to Collection

Review Medicine, General & Internal

Kidney transplant wait list: Review and current trends

Lindsay M. Clayton et al.

JAAPA-JOURNAL OF THE AMERICAN ACADEMY OF PHYSICIAN ASSISTANTS (2018)

Add to Collection

Review Engineering, Biomedical

Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Allograft Function After Renal Transplantation: Evaluation of the Current Status and Future Insights

Maria Cappuccilli et al.

ARTIFICIAL ORGANS (2018)

Add to Collection

Article Cardiac & Cardiovascular Systems

Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria

Axel C. Carlsson et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2017)

Add to Collection

Article

Prostate cancer proteomics: Current trends and future perspectives for biomarker discovery

Cristiana Pistol Tanase et al.

Oncotarget (2017)

Add to Collection

Article Urology & Nephrology

Use of Proteomics To Investigate Kidney Function Decline over 5 Years

Axel C. Carlsson et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Add to Collection

Article Urology & Nephrology

Proteins in Preservation Fluid as Predictors of Delayed Graft Function in Kidneys from Donors after Circulatory Death

Bas W. M. van Balkom et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Add to Collection

Review Urology & Nephrology

New developments in transplant proteomics

Julie Ho et al.

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2017)

Add to Collection

Article Urology & Nephrology

Mining the human urine proteome for monitoring renal transplant injury

Tara K. Sigdel et al.

KIDNEY INTERNATIONAL (2016)

Add to Collection

Review Medical Laboratory Technology

Biomarkers in Transplantation-Proteomics and Metabolomics

Uwe Christians et al.

THERAPEUTIC DRUG MONITORING (2016)

Add to Collection

Review Immunology

The Use of Genomics and Pathway Analysis in Our Understanding and Prediction of Clinical Renal Transplant Injury

Madhav C. Menon et al.

TRANSPLANTATION (2016)

Add to Collection

Article Immunology

Elevated Urinary Matrix Metalloproteinase-7 Detects Underlying Renal Allograft Inflammation and Injury

Julie Ho et al.

TRANSPLANTATION (2016)

Add to Collection

Article Immunology

Clusterin in Kidney Transplantation: Novel Biomarkers Versus Serum Creatinine for Early Prediction of Delayed Graft Function

Timothy J. Pianta et al.

TRANSPLANTATION (2015)

Add to Collection

Article Immunology

Elevated Urinary CXCL10-to-Creatinine Ratio Is Associated With Subclinical and Clinical Rejection in Pediatric Renal Transplantation

Tom D. Blydt-Hansen et al.

TRANSPLANTATION (2015)

Add to Collection

Article Immunology

Genomic and proteomic fingerprints of acute rejection in peripheral blood and urine

Song Ong et al.

TRANSPLANTATION REVIEWS (2015)

Add to Collection

Article Biology

Pathway and network analysis in proteomics

Xiaogang Wu et al.

JOURNAL OF THEORETICAL BIOLOGY (2014)

Add to Collection

Article Biochemical Research Methods

The Identification of Novel Potential Injury Mechanisms and Candidate Biomarkers in Renal Allograft Rejection by Quantitative Proteomics

Tara K. Sigdel et al.

MOLECULAR & CELLULAR PROTEOMICS (2014)

Add to Collection

Article Transplantation

Factors influencing survival after kidney transplant failure

Jennifer A. McCaughan et al.

TRANSPLANTATION RESEARCH (2014)

Add to Collection

Article Surgery

Multicenter Validation of Urinary CXCL9 as a Risk-Stratifying Biomarker for Kidney Transplant Injury

D. E. Hricik et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2013)

Add to Collection

Article Medical Laboratory Technology

Biomarker discovery in transplantation-proteomic adventure or mission impossible?

Katrin Kienzl-Wagner et al.

CLINICAL BIOCHEMISTRY (2013)

Add to Collection

Article Biochemistry & Molecular Biology

STRING v9.1: protein-protein interaction networks, with increased coverage and integration

Andrea Franceschini et al.

NUCLEIC ACIDS RESEARCH (2013)

Add to Collection

Article Biochemical Research Methods

Identification of a protein signature in renal allograft rejection

Diane M. Cibrik et al.

PROTEOMICS CLINICAL APPLICATIONS (2013)

Add to Collection

Review Surgery

Proteomics and metabolomics in renal transplantation-quo vadis?

Rahul Bohra et al.

TRANSPLANT INTERNATIONAL (2013)

Add to Collection

Review Urology & Nephrology

Preemptive kidney transplantation: Has it come of age?

Yihung Huang et al.

NEPHROLOGIE & THERAPEUTIQUE (2012)

Add to Collection

Article Immunology

Urinary Neutrophil Gelatinase-Associated Lipocalin Accurately Detects Acute Allograft Rejection Among Other Causes of Acute Kidney Injury in Renal Allograft Recipients

Nils Heyne et al.

TRANSPLANTATION (2012)

Add to Collection

Article Biochemical Research Methods

Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods

Olwyn Johnston et al.

PROTEOMICS CLINICAL APPLICATIONS (2011)

Add to Collection

Review Biochemical Research Methods

Profiling the proteome in renal transplantation

Tara K. Sigdel et al.

PROTEOMICS CLINICAL APPLICATIONS (2011)

Add to Collection

Review Immunology

Proteomics-A Blessing or a Curse? Application of Proteomics Technology to Transplant Medicine

Katrin Kienzl-Wagner et al.

TRANSPLANTATION (2011)

Add to Collection

Article Immunology

Chemokines and Their Receptors in Human Renal Allotransplantation

Denise J. Lo et al.

TRANSPLANTATION (2011)

Add to Collection

Article Biochemical Research Methods

Shotgun proteomics identifies proteins specific for acute renal transplant rejection

Tara K. Sigdel et al.

PROTEOMICS CLINICAL APPLICATIONS (2010)

Add to Collection

Article Surgery

High pretransplant serum levels of CXCL9 are associated with increased risk of acute rejection and graft failure in kidney graft recipients

Mario Rotondi et al.

TRANSPLANT INTERNATIONAL (2010)

Add to Collection

Article Biochemistry & Molecular Biology

PID: the Pathway Interaction Database

Carl F. Schaefer et al.

NUCLEIC ACIDS RESEARCH (2009)

Add to Collection

Article Biochemical Research Methods

Urinary proteomic analysis of chronic allograft nephropathy

Edmond O'Riordan et al.

PROTEOMICS CLINICAL APPLICATIONS (2008)

Add to Collection

Article Urology & Nephrology

Proteomic analysis of urine in kidney transplant patients with BK virus nephropathy

Timo Jahnukainen et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)

Add to Collection

Article Surgery

Safety and adequacy of renal transplant protocol biopsies

A Schwarz et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2005)

Add to Collection

Article Surgery

Proteomic-based identification of cleaved urinary β2-microglobulin as a potential marker for acute tubular injury in renal allografts

S Schaub et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2005)

Add to Collection

Article Medicine, General & Internal

Use of proteomic patterns in serum to identify ovarian cancer

EF Petricoin et al.

LANCET (2002)

Add to Collection

Article Pathology

Development of a novel proteomic approach for the detection of transitional cell carcinoma of the bladder in urine

A Vlahou et al.

AMERICAN JOURNAL OF PATHOLOGY (2001)

Add to Collection

© Peeref 2019-2024. All rights reserved.