Journal
ADVANCES IN OPTICS AND PHOTONICS
Volume 8, Issue 1, Pages 1-103Publisher
Optica Publishing Group
DOI: 10.1364/AOP.8.000001
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Funding
- Ministerio de Economia y Competitividad (Spain) [MAT 2013-47395-C4-1-R]
- Agency for Science, Technology and Research (A*STAR, Singapore) [1231AFG028]
- Tokyo University of Science (Japan) [S0901020]
- Agence Nationale de la Recherche [Natlurium 08-NANO-025, PEPSI 14-CE08-0016-01]
- Grants-in-Aid for Scientific Research [15H05950] Funding Source: KAKEN
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The tremendous progress in the synthesis of different inorganic nanoparticles with pre-tailored size, shape, structural, compositional, and surface properties has significantly raised their potential applications in biomedicine. Optically active inorganic nanoparticles are those that, based on inorganic materials, can produce fluorescence or scattered light under suitable optical excitation. These outgoing radiations can be conveniently used for bioimaging purposes. In this work, the different types of optically active inorganic nanoparticles that are being used for optical bioimaging are reviewed in detail. Special attention is paid to fluorescent and inorganic persistent luminescence nanoparticles and how their different excitation mechanisms (no-photon, one-photon, or multi-photon excited fluorescence) and working spectral ranges can be conveniently applied for in vitro and in vivo high-contrast optical bioimaging. (C) 2016 Optical Society of America
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