Journal
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
Volume 4, Issue 12, Pages 6534-6542Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acssuschemeng.6b01351
Keywords
Microfabrication; Bacterial cellulose; Hydrogel Microfibers; Sustainable; Antibacterial
Categories
Funding
- Advanced Catalysis and Green Manufacturing Collaborative Innovation Center (Changzhou University) [213164]
- Synergetic Research Center for Advanced Micro-Nano Materials and Technology of Jiangsu Province
- Collaborative Innovation Center of Suzhou Nano Science and Technology
- National Natural Science Foundation of China [51272106, 51303083, 21275106]
- Major State Basic Research Development Program (973 program) [2013CB932702]
- Fundamental Research Funds for the Central Universities [30920130121001]
- Research Fund for the Doctoral Program of Higher Education of China (RFDP) [20123219110015]
- Nature Science Foundation of Jiangsu Province [BK20130759]
- Science and Technology Innovation Fund of QiXia District [201528]
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD, China)
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Microbial infections continue to pose a serious threat to human health, thus calling attention to the development of new materials with better antibacterial applications. Here we report a microfluidic approach to fabricate core-shell GO-AgNPs/BC (graphene oxide-silver nanoparticles/bacterial cellulose) hydrogel microfibers with controlled-releasing and long-lasting antibacterial performance. Meters of the composite microfibers can be produced in 1 min by using a homemade microfluidic wet-spinning device. The as-prepared microfibers exhibit well-controlled morphological features at the nanoscale and excellent mechanical properties. We have demonstrated that the composite microfibers can effectively sterilize both Gram positive and negative bacterial strains, while remaining friendly to normal mammalian cells. This flexible approach of synthesizing core shell composite microfibers promises important biomedical applications including materials science, tissue engineering, and regenerative medicine.
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