☆ 4.8 Review

Evolution of Aza-BODIPY dyes-A hot topic

COORDINATION CHEMISTRY REVIEWS (2024)

Related references

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Review Materials Science, Multidisciplinary

Non-aryl substituted aza-BODIPYs at 1,7-or 3,5-sites: synthesis, structures, optical properties, and applications

Dongxiang Zhang et al.

Summary: aza-BODIPYs are a class of compounds with excellent photophysical properties, showing great potential in biomolecular sensing, photoelectric materials, and tumor phototherapy. However, there are limited reports on non-aryl substituted aza-BODIPYs. This review discusses the structures and applications of non-aryl substituted aza-BODIPYs at 1,7- or 3,5-sites for the first time, providing valuable reference for further design strategies and application prospects in the aza-BODIPY system.

JOURNAL OF MATERIALS CHEMISTRY C (2023)

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Article Materials Science, Biomaterials

Self-Assembled Aza-BODIPY and Iron(III) Nanoparticles for Photothermal-Enhanced Chemodynamic Therapy in the NIR-II Window

Jinjin Zhang et al.

Summary: In this study, a three-dimensional network structure was constructed using metal coordination between catechol-functionalized aza-boron dipyrromethenes and iron ions. The resulting ABFe nanoparticles (NPs) showed intense absorption in the second near-infrared (NIR-II) range and excellent photothermal stability. Additionally, ABFe NPs were capable of generating reactive oxygen species for chemodynamic therapy, which was enhanced by their photothermal performance. The in vitro and in vivo experiments demonstrated the potential of ABFe NPs in photoacoustic imaging and photothermal-enhanced chemodynamic therapy under NIR-II laser irradiation.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2023)

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Article Biochemistry & Molecular Biology

Multifunctional organic nanomaterials with ultra-high photothermal conversion efficiency for photothermal therapy and inhibition of cancer metastasis

Xiao-Zhen Yang et al.

Summary: This study developed two organic photothermal agents based on aza-BODIPY, which showed improved optical properties and demonstrated efficacy in tumor inhibition and metastasis prevention when encapsulated into nanoparticles.

BIOORGANIC CHEMISTRY (2023)

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Review Chemistry, Inorganic & Nuclear

BODIPY-based probes for hypoxic environments

Lizhi Gai et al.

Summary: The hypoxic environment is a significant characteristic of solid tumors, resulting from an imbalance between oxygen supply and consumption. Recent progress has been made in designing hypoxia probes derived from BODIPY scaffolds. These probes have attracted particular attention and are closely related to tumor resistance to various therapies. This review focuses on the construction strategies, recognition mechanisms, and biological imaging applications of various BODIPY-based hypoxia probes, aiming to inspire novel approaches and innovations for designing fluorescent probes for imaging hypoxic environments and promoting the development of tumor diagnostics and hypoxia-responsive anti-cancer nanomedicines.

COORDINATION CHEMISTRY REVIEWS (2023)

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Review Chemistry, Inorganic & Nuclear

Evolution of BODIPY as triplet photosensitizers from homogeneous to heterogeneous: The strategies of functionalization to various forms and their recent applications

Danfeng Wang et al.

Summary: The BODIPY chromophore is a versatile fluorophore widely used in various research fields, especially in life science and material science. It has made significant advancements in the past decades, particularly as a photosensitizer. The key to practical applications lies in structural functionalization, and the evolution of BODIPY-based materials as photosensitizers is currently underway.

COORDINATION CHEMISTRY REVIEWS (2023)

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Article Chemistry, Applied

Naphthodipyrrolopyrrole-based Aza-BODIPY dye for N-type organic field-effect transistors

Chuanqi Miao et al.

Summary: In this study, a naphthodipyrrolopyrrole-based dimeric aza-boron dipyrromethene (Aza-BODIPY) dye was designed and synthesized as a strong electron-deficient chromophore for n-type semiconductors. The material exhibited a blue spectral shift in solution phase and demonstrated good electron mobility, making it a promising candidate for organic field-effect transistors.

DYES AND PIGMENTS (2023)

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Article Chemistry, Medicinal

NIR-II Aza-BODIPY Dyes Bioconjugated to Monoclonal Antibody Trastuzumab for Selective Imaging of HER2-Positive Ovarian Cancer

Amelie Godard et al.

Summary: Using fluorescence-guided surgery (FGS) with NIR-II dyes targeting human epidermal growth factor receptor 2 (HER2)-positive ovarian tumors showed favorable tumor accumulation and selective targeting of HER2 positive tumors. These bioconjugated NIR-II-emitting dyes displayed prolonged stability in serum and maintained affinity toward HER2 in vitro, indicating their potential for NIR-II FGS in the cancer setting. This study suggests that the use of NIR-II dyes in FGS can improve the complete resection of microscopic ovarian tumors.

JOURNAL OF MEDICINAL CHEMISTRY (2023)

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Article Chemistry, Multidisciplinary

Biomimetic Approach to Promote Cellular Uptake and Enhance Photoacoustic Properties of Tumor-Seeking Dyes

Amanda K. East et al.

Summary: The attachment of glucose to drugs and imaging agents enables cancer cell targeting via interactions with GLUT1 overexpressed on the cell surface. We have developed a biomimetic multivalent glucose moiety (mvGlu) to overcome the limitations of solubility and spectral unmixing in imaging agents, leading to significant enhancements in photoacoustic (PA) signal. We have also demonstrated the utility of mvGlu in targeting cancer cells with ultra-low dye concentrations and in developing a logic-gated acoustogenic probe for detecting intratumoral copper.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2023)

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Article Chemistry, Applied

Panchromatic small-molecule organic solar cells based on a pyrrolopyrrole aza-BODIPY with a small energy loss

Ru Feng et al.

Summary: The authors present two new pyrrolopyrrole aza-BODIPY (PPAB) based panchromatic chromophores, TT-2PPAB and DFBT-2PPAB, with an acceptor-donor-acceptor configuration. Among them, TT-2PPAB exhibits a moderate power conversion efficiency (PCE) of 3.11% when combined with [6,6]-phenyl-C71 butyric acid methyl ester (PC71BM) acceptor, with an energy loss of 0.48 eV, smaller than the empirical limit of 0.6 eV. The efficient photovoltaic performance of the TT-2PPAB-based device is attributed to the sufficiently deep LUMO level of TT-2PPAB for charge transfer to PC71BM, as revealed by electrochemistry and theoretical calculations.

DYES AND PIGMENTS (2023)

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Review Chemistry, Applied

Red and NIR emitting ring-fused BODIPY/aza-BODIPY dyes

Vandana Kumari Shukla et al.

Summary: BODIPY dyes have excellent features but their application is limited due to narrow absorption and emission range. Recent developments in introducing fused BODIPYs and aza-BODIPYs have shown promise in red shifting the photophysical properties. This review summarizes their properties, synthesis, and applications in biomedical and optoelectronic fields.

DYES AND PIGMENTS (2023)

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Article Chemistry, Organic

A supramolecular near-infrared nanophotosensitizer from host-guest complex of lactose-capped pillar[5]arene with aza-BODIPY derivative for tumor eradication

Jiaxuan Li et al.

Summary: A novel dual phototherapeutic aza-BODIPY supramolecular vesicle was constructed by forming an amphiphilic complex between lactose-capped pillar[5]arene (LacP5) and an aza-BODIPY derivative (BSTA). The supramolecular vesicles showed good stability under physiological conditions, active targeting to liver cancer cells, stimuli-responsive drug release, and dual-mode imaging in vivo (fluorescence and photothermal). The release of aza-BODIPY and disulfiram (DSF) drugs from the vesicles in response to glutathione (GSH) in tumor cells allowed for dual phototherapy and chemotherapy. In vivo antitumor experiments demonstrated enhanced antitumor effects and good biosafety of the dual phototherapy and chemotherapy combination. The LacP5 superset of BSTA supramolecular phototherapeutic vesicles hold great potential in tumor therapy.

ORGANIC CHEMISTRY FRONTIERS (2023)

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Article Chemistry, Multidisciplinary

A Facile, Protein-Derived Supramolecular Theranostic Strategy for Multimodal-Imaging-Guided Photodynamic and Photothermal Immunotherapy In Vivo

Hong-Bo Cheng et al.

Summary: This article introduces a novel supramolecular theranostic system that combines biomarker protein activation and a host-guest strategy. The authors demonstrate the design of a nanoparticulate theranostic agent that can detect albumin and treat cancer. The system also exhibits enhanced biocompatibility and photothermal conversion efficiency, making it a promising strategy for photodynamic and photothermal immunotherapy.

ADVANCED MATERIALS (2022)

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Article Chemistry, Analytical

Engineering a Ratiometric Photoacoustic Probe with a Hepatocyte-Specific Targeting Ability for Liver Injury Imaging

Xiao-Peng Fan et al.

Summary: In this study, an amphiphilic molecular probe was developed for in situ imaging of drug-induced liver injury. The probe showed selectivity and sensitivity towards the target compound and could be used to assess liver injury and analyze the therapeutic efficacy of hepatoprotective medicines.

ANALYTICAL CHEMISTRY (2022)

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Article Chemistry, Multidisciplinary

A Bright, Renal-Clearable NIR-II Brush Macromolecular Probe with Long Blood Circulation Time for Kidney Disease Bioimaging

Chenzhi Yao et al.

Summary: A new aza-boron-dipyrromethene (aza-BODIPY) brush macromolecular probe (FBP 912) with high brightness and renal clearance efficiency has been developed for non-invasive diagnosis of kidney diseases. This probe shows superior performance compared to traditional fluorophores in passive targeted imaging of tumors and active targeted imaging of renal cell carcinoma.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

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Article Chemistry, Multidisciplinary

Femtosecond Spectroscopy and Nonlinear Optical Properties of aza-BODIPY Derivatives in Solution

Hao-Jung Chang et al.

Summary: This study investigated the fast relaxation processes in the excited electronic states of functionalized aza-boron-dipyrromethene (aza-BODIPY) derivatives, including their linear photophysical, photochemical, and nonlinear optical properties. It was found that nonfluorescent derivatives exhibited optical gain in the near infrared range under femtosecond excitation. The study also discussed the role of bromine substituents in the molecular structures of these derivatives, and the excited states involved in electronic transitions were investigated using quantum-chemical TD-DFT calculations. The high two-photon absorption and excited-state absorption cross-sections, along with the measured photostability, suggest potential applications in photonics and optical limiting.

CHEMISTRY-A EUROPEAN JOURNAL (2022)

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Article Chemistry, Applied

Near-infrared vinyl-containing aza-BODIPY nanoparticles as photosensitizer for phototherapy

Yanyan Wang et al.

Summary: A novel vinyl-containing pyrrole compound was developed through the reaction of vinyl-containing ketones with 3-phenyl-2H-azirine in the presence of LDA. This compound was then used to prepare asymmetric vinyl-containing azaBDPs 1-8, avoiding the use of Knoevenagel condensation. Among them, the formed azaBDP nanoparticles (7-NPs) exhibited excellent photothermal stabilities and a high photothermal conversion efficiency (eta = 55%) in the aza-BODIPY system, effectively killing cancer cells through photothermal conversion, showing potential as a tumor phototherapeutic agent.

DYES AND PIGMENTS (2022)

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Article Chemistry, Applied

Recent advances of NIR dyes of pyrrolopyrrole cyanine and pyrrolopyrrole aza-BODIPY: Synthesis and application

Lingyun Wang et al.

Summary: Organic dyes with strong absorption and emission in the near-infrared region have attracted increasing attention. Promising NIR chromophores, PPCy and PPAB, possess outstanding characteristics such as high extinction coefficients, fluorescence quantum yields, and stability. By molecular design and photophysical control, efficient PPCy and PPAB dyes can be developed for various practical applications.

DYES AND PIGMENTS (2022)

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Article Chemistry, Medicinal

Discovery of an Amino Acid-Modified Near-Infrared Aza-BODIPY Photosensitizer as an Immune Initiator for Potent Photodynamic Therapy in Melanoma

Zhiliang Yu et al.

Summary: In this study, a series of amino acid-modified aza-BODIPY photosensitizers were synthesized and evaluated for photodynamic therapy. Among them, the aspartic acid-modified PS 1a showed the most potent efficacy with enhanced water solubility, increased O-1(2) generation efficiency, and improved photo-dark toxicity ratio. Subcellular localization, cell-based ROS production, and cell death pathway of 1a were studied, and in vivo assays demonstrated its reasonable distribution and clearance. Compared to other PSs, 1a not only exhibited excellent PDT effect with a low drug dose and single-time photoirradiation, but also induced antitumor immunological response.

JOURNAL OF MEDICINAL CHEMISTRY (2022)

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Article Chemistry, Organic

Effect of the Aza-N-Bridge and Push-Pull Moieties: A Comparative Study between BODIPYs and Aza-BODIPYs

Clara Schafer et al.

Summary: This study provides a photophysical evaluation of BODIPY and aza-BODIPY derivatives, leading to a deeper understanding of the structure-function relationship and facilitating the design of tailor-made molecules in the future.

JOURNAL OF ORGANIC CHEMISTRY (2022)

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Review Biochemistry & Molecular Biology

BODIPY Conjugates as Functional Compounds for Medical Diagnostics and Treatment

Elena Antina et al.

Summary: Fluorescent dyes, particularly BODIPY, are promising for labeling and bio-visualization of body cells. They exhibit excellent photophysical properties and have a huge potential for practical applications in medicine, including as biomarkers and therapeutic agents. Recent applications of BODIPY include the development of conjugates with drugs, labeling of biomolecules, and obtaining functional materials through conjugation with other particles.

MOLECULES (2022)

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Article Chemistry, Multidisciplinary

Synthesis and photophysical properties of nitrated aza-BODIPYs

Samuel R. Zarcone et al.

Summary: Nitration of the 2- and 6-positions in aza-BODIPYs can significantly impact their absorption and emission profiles, resulting in exceptional photophysical tunability and near-IR emission.

NEW JOURNAL OF CHEMISTRY (2022)

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Article Optics

Orthogonal Aza-BODIPY-BODIPY dyad as heavy-atom free photosensitizer for photo-initiated antibacterial therapy

Dongliang Yang et al.

Summary: A novel halogen-free photosensitizer, NDB, was synthesized in this study. The ROS generation capability of NDB under 730 nm laser illumination was found to be 3-fold higher than that of the commercial ICG, suggesting its potential application in photo-initiated antibacterial therapy.

JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES (2022)

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Article Materials Science, Biomaterials

Supramolecular J-aggregates of aza-BODIPY by steric and π-π nteractions for NIR-II phototheranostics

Youliang Tian et al.

Summary: This study successfully synthesized aza-BODIPY dye with J-aggregation characteristics by introducing steric hindrance and a pi-bridge. The dye-templated self-assembly formed supramolecular J-aggregates with a regular lamellar stacking structure. The resulting J-NPs demonstrated good water solubility and small size, and showed excellent NIR-II fluorescence imaging capabilities and anti-tumor effects.

JOURNAL OF MATERIALS CHEMISTRY B (2022)

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Article Materials Science, Biomaterials

Stable twisted conformation aza-BODIPY NIR-II fluorescent nanoparticles with ultra-large Stokes shift for imaging-guided phototherapy

Youliang Tian et al.

Summary: By developing a novel NIR-II photosensitizer through simple synthesis methods, we achieved excellent fluorescence imaging performance and tumor therapeutic effects.

JOURNAL OF MATERIALS CHEMISTRY B (2022)

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Review Chemistry, Multidisciplinary

Near-infrared absorbing (>700 nm) aza-BODIPYs by freezing the rotation of the aryl groups

Yanyan Wang et al.

Summary: This review comprehensively summarizes the recent development of ring-fused aza-BODIPY dyes since 2002, with a focus on the design, synthesis, and potential applications in the near-infrared (NIR) region.

CHINESE CHEMICAL LETTERS (2022)

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Article Chemistry, Applied

Synthesis, structure and photochemical properties of asymmetric NMe2-bearing aza-BODIPYs as novel photothermal agents

Jinhui Li et al.

Summary: A series of asymmetric aza-BODIPYs carrying the dimethylamino (-NMe2) group were synthesized, and dye nanoparticles with photothermal properties were prepared. These nanoparticles can efficiently kill cancer cells through the photothermal effect by near-infrared laser irradiation.

DYES AND PIGMENTS (2022)

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Article Chemistry, Physical

Aza-BODIPY-based phototheranostic nanoagent for tissue oxygen auto-adaptive photodynamic/photothermal complementary therapy

Meijiao Zhao et al.

Summary: This study introduces an intelligent nanoagent, BDP-Oxide nanoparticles, which can initiate optimal tumor treatment based on localized oxygen levels, achieving photodynamic/photothermal complementary therapy and significantly suppressing solid tumor growth.

NANO RESEARCH (2022)

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Article Polymer Science

Novel Near-Infrared Fluorescent Nanoprobe Synthesized by the RAFT-Mediated PISA Strategy for Hypoxia-Triggered Tumor Imaging and Azoreductase-Responsive Drug Release

Shuyuan Wang et al.

Summary: This study reports the synthesis of hypoxia-responsive near-infrared fluorescent nanoprobes through a RAFT-mediated PISA strategy, which enables synchronous drug release and cell imaging. The nanoparticles with different morphologies and sizes are synthesized by the PISA strategy, and the dissociation of the nanoprobes and NIR fluorescence emission are observed under hypoxia due to the cleavage of azo bonds. The in situ DOX-loaded nanoprobes by the PISA demonstrate synchronous drug release and NIR fluorescence enhancement against mouse colon cancer cells under hypoxia.

MACROMOLECULAR CHEMISTRY AND PHYSICS (2022)

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Article Spectroscopy

Near-Infrared fluorescent unsymmetrical aza-BODIPYs: Synthesis, photophysics and TD-DFT calculations

Arkadiusz Gut et al.

Summary: In this study, the synthesis and properties of four unsymmetrical aza-BODIPYs with near-infrared (NIR) fluorescence were reported. These molecules exhibited highly desirable photophysical and photochemical properties due to the presence of both strongly electron-withdrawing p-nitrophenyl rings and mildly electron-donating p-methoxyphenyl rings within the aza-BODIPY core. The unsymmetrical aza-BODIPYs showed NIR emission with wavelengths ranging from 699 nm to 718 nm, along with fluorescence quantum yields ranging from 0.22 to 0.49 and fluorescence lifetimes ranging from 1.90 ns to 3.59 ns. A specific aza-BODIPY with electron-donating and electron-withdrawing substituents at the 3 and 5 positions, respectively, was identified as a cell-permeable, NIR emitting fluorophore suitable for bioimaging.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022)

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Article Materials Science, Multidisciplinary

Aza-BODIPY nanoparticles for near-infrared triggered synergistic photothermal and photodynamic antibacterial therapy

Shuang Song et al.

Summary: This study prepares a new PTT/PDT dual-modality antibacterial agent ABDP NPs, which show superior bactericidal effects against S. aureus, E. coli, and MRSA under the control of an 808nm laser. The wounds treated with ABDP NPs plus NIR laser irradiation exhibit better healing outcomes.

JOURNAL OF MATERIALS SCIENCE (2022)

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Article Chemistry, Physical

Near-infrared aza-BODIPYs bearing tetraphenylethylene: Synthesis, photophysical studies, and cell imaging application

Sirimongkon Aryamueang et al.

Summary: This study provides a simple method for synthesizing tetraphenylethylene-modified aza-BODIPY dyes with aggregation-enhanced emission, and further investigates their properties through various experiments and calculations. The research reveals efficient intramolecular energy transfer between the dyes, resulting in increased fluorescence in aggregated form.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2022)

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Article Chemistry, Multidisciplinary

Nitric-Oxide-Releasing aza-BODIPY: A New Near-Infrared J-Aggregate with Multiple Antibacterial Modalities

Xinyao Bao et al.

Summary: This study reports the development of a near-infrared J-aggregate that releases nitric oxide. The J-aggregate is formed within micellar nanoparticles and can be finely tuned for nitric oxide release and photothermal conversion efficiency by adjusting the loading contents. The combination of nitric oxide release and photothermal therapy shows potential for enhanced antibacterial activity and reduced inflammation in the treatment of MRSA infection.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

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Article Chemistry, Multidisciplinary

Access to Pyridinyl or Pyridinium Aza-BODIPYs with Tunable Near-Infrared Fluorescence through ICT from 4-Pyridinyl Pyrroles

Chang Liu et al.

Summary: This manuscript presents a facile method for synthesizing pyridine-substituted pyrroles and investigates their spectroscopic properties. The localization of these pyrroles in lysosomes suggests potential applications in avoiding the harmful effects of traditional fluorescent dyes. The study also explores the possibility of using these pyrroles as photosensitizers against microbials or tumors.

CHEMISTRY-A EUROPEAN JOURNAL (2022)

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Article Biochemistry & Molecular Biology

Asymmetric AZA-BODIPY with Optical Gain in the Near-Infrared Region

Tersilla Virgili et al.

Summary: In recent years, the development of organic compounds emitting in the near-infrared (NIR) region has attracted a lot of interest due to their applications in biosensing and light detection and ranging (LiDAR). This paper presents the ultrafast spectroscopy of an asymmetric AZA-BODIPY molecule, which shows relevant photophysical changes with increasing concentration. The results demonstrate the presence of a broad and long-living optical gain band in the NIR region for a very concentrated solution, paving the way for the development of a new organic laser system in the near-infrared spectral region.

MOLECULES (2022)

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Article Chemistry, Multidisciplinary

Synthesis of Aza-BODIPYs, Their Differential Binding for Cu(II), and Results of Bioimaging as Fluorescent Dyes of Langerhans beta-Cells

Yaneth C. Pino et al.

Summary: This paper reports the synthesis, characterization, and evaluation of four azaBODIPY compounds as metal sensors and cell staining probes. The results demonstrate that these compounds possess selective optical properties that can be applied in the biomedical field.

ACS OMEGA (2022)

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Article Chemistry, Organic

Aminophenyl-Aza-BODIPY

Dmitry Merkushev et al.

Summary: aza-BODIPYs are a promising class of IR fluorescent dyes that can act as fluorescent sensors when specific substituents are introduced. In this work, a new aminophenyl-substituted aza-BODIPY was synthesized for future application as a near-IR pH probe.

MOLBANK (2022)

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Article Chemistry, Multidisciplinary

Unique Double Intramolecular and Intermolecular Exciton Coupling in Ethene-Bridged aza-BODIPY Dimers for High-Efficiency Near-Infrared Photothermal Conversion and Therapy

Xing Guo et al.

Summary: In this study, we developed ethene-bridged aza-BODIPY dimers with intramolecular exciton splitting and produced J-type aggregated nanoparticles by encapsulating the dimers into F-127 polymer. The nanoparticles showed obvious intermolecular exciton coupling and redshifted absorption and emission peaks. The fabricated nanoagents exhibited high photothermal conversion ability and photostability, leading to complete tumor ablation through laser irradiation.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

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Review Chemistry, Inorganic & Nuclear

Conformationally restricted and ring-fused aza-BODIPYs as promising near infrared absorbing and emitting dyes

Jun Wang et al.

Summary: Aza-BODIPY is an important class of heteroatom-containing BODIPY analogue that can be modified to extend its absorption and emission wavelengths, making it promising for the development of near infrared chromophores and fluorophores.

COORDINATION CHEMISTRY REVIEWS (2022)

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Article Chemistry, Physical

A self-assembled aza-BODIPY linked dicyanostilbenzene with a large Stokes shift, AIE, mechanochromism and singlet oxygen yield

Wei Ding et al.

Summary: In this study, a novel molecule with unique properties, including the ability to self-assemble into columnar phase and organogels, as well as near-infrared, AIE, and mechanochromic luminescence characteristics, was successfully synthesized.

JOURNAL OF MOLECULAR LIQUIDS (2022)

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Article Spectroscopy

A novel TCF-aza-BODIPY-based near-infrared fluorescent probe for highly selective detection of hypochlorous acid in living cells

Wen-Jing Shi et al.

Summary: Hypochlorous acid/hypochlorite (HOCl/ClO-) plays important roles in killing bacterial and causing damage to living tissues, and developing fluorescent probes for HOCl/ClO- detection is of great significance.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022)

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Article Nanoscience & Nanotechnology

Hypoxia-Activatable Nanovesicles as In Situ Bombers for Combined Hydrogen-Sulfide-Mediated Respiration Inhibition and Photothermal Therapy

Qi Yu et al.

Summary: Photothermal therapy (PTT) is a promising cancer treatment, but its efficacy is limited by the self-recovery of cancer cells. To overcome this limitation, researchers have introduced hydrogen sulfide (H2S) to enhance the efficacy of PTT. They developed nanovesicles for the delivery of H2S and synergistic H2S gas therapy/PTT. The results demonstrate that this new strategy has good antitumor effects.

ACS APPLIED MATERIALS & INTERFACES (2022)

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Article Nanoscience & Nanotechnology

PEGylated Aza-BODIPY Nanoparticles for Photothermal Therapy

Sastiya Kampaengsri et al.

Summary: The development of a stable polymer conjugated nanoparticle, aza-BODIPY-mPEG, with excellent photothermal conversion characteristics, shows promising potential as a material for cancer photothermal therapy.

ACS APPLIED BIO MATERIALS (2022)

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Article Materials Science, Biomaterials

An aza-BODIPY-based NIR-II luminogen enables efficient phototheranostics

Na Yang et al.

Summary: In this study, a new NIR-II fluorescent probe CB1 was designed and synthesized, which showed excellent imaging performance and photothermal properties. Both in vitro and in vivo assessments confirmed that CB1 nanoparticles could be used as theranostic agents for NIR-II fluorescence imaging and tumor growth inhibition with negligible side effects. This work provides a promising approach for constructing a new platform for cancer diagnosis and therapy.

BIOMATERIALS SCIENCE (2022)

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Article Chemistry, Multidisciplinary

Activatable photothermal agents with target-initiated large spectral separation for highly effective reduction of side effects

Jie Sun et al.

Summary: The study reports the construction of an activatable photothermal agent (PTA) with target-initiated large spectral separation for highly effective reduction of side effects. In vitro and in vivo experiments demonstrated that the PTA can selectively induce photothermal ablation of cancer cells and tumors without damaging normal tissues.

CHEMICAL SCIENCE (2022)

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Article Materials Science, Multidisciplinary

Versatile aza-BODIPY-based low-bandgap conjugated small molecule for light harvesting and near-infrared photodetection

Gurudutt Bhat et al.

Summary: The versatile nature of organic conjugated materials allows them to be seamlessly integrated into various optoelectronic devices. By combining boron-azadipyrromethene with triphenylamine, a multi-purpose conjugated small molecule is developed. This molecule can be used as either a charge transporting interlayer or a light-sensing semiconducting layer in optoelectronic devices. It exhibits excellent performance in perovskite solar cells and near-infrared organic photodetectors.

INFOMAT (2022)

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Article Chemistry, Multidisciplinary

Design, synthesis and applications of NIR-emissive scaffolds of diketopyrrolopyrrole-aza-BODIPY hybrids

Lingyun Wang et al.

Summary: A facile synthetic method was used to synthesize diketopyrrolopyrrole-aza-BODIPY hybrids. The resulting fluorophores showed high absorption and emission wavelengths in solution, as well as good biocompatibility and strong ROS generation ability, making them useful for bioimaging and photodynamic therapy. Furthermore, a novel NIR-emissive conjugated polymer can be constructed using this method.

CHEMICAL COMMUNICATIONS (2022)

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Article Chemistry, Organic

Synthesis of trifluoromethylated aza-BODIPYs as fluorescence-19F MRI dual imaging and photodynamic agents

Anfeng Li et al.

Summary: This research synthesized a series of tetra-trifluoromethylated aza-boron dipyrromethenes and systematically studied their physicochemical properties. It identified one compound with 12 symmetrical fluorines as a dual-imaging photosensitizer for photodynamic therapy.

ORGANIC & BIOMOLECULAR CHEMISTRY (2022)

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Article Materials Science, Multidisciplinary

Novel butterfly-shaped AIE-active pyrrolopyrrole aza-BODIPYs: synthesis, bioimaging and diamine/polyamine detection

Wenting Li et al.

Summary: In this study, novel near-infrared dyes with aggregation-induced emission (AIE) were successfully constructed. Their photophysical properties and solvatochromic behavior were investigated using experimental and theoretical methods. One of the dyes showed potential application in bioimaging in HeLa cells when encapsulated in nanoparticles, and demonstrated sensitive and selective detection of amines.

JOURNAL OF MATERIALS CHEMISTRY C (2022)

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Article Biology

Characterization of nanoparticles combining polyamine detection with photodynamic therapy

Wenting Li et al.

Summary: The research developed a new photosensitizer nanoparticle that can react with over-expressed polyamines in cancer cells, producing two photosensitizers with enhanced phototoxicity. Simultaneously, the nanoparticles provide ratiometric fluorescence imaging of intracellular polyamines. This combination of polyamine consumption with a chemical reaction offers a new approach for polyamine detection and photodynamic therapy, potentially leading to depletion of polyamines for cancer treatment and prevention.

COMMUNICATIONS BIOLOGY (2021)

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Article Chemistry, Multidisciplinary

An Electron-Accepting aza-BODIPY-Based Donor-Acceptor-Donor Architecture for Bright NIR Emission

Yuto Kage et al.

Summary: A bright NIR fluorescent molecule based on the D-A-D approach using TPA and PPAB showed enhanced performance, with increased brightness and solvatochromic behavior in emission. This novel emitter demonstrated high potential for efficient NIR optoelectronic applications.

CHEMISTRY-A EUROPEAN JOURNAL (2021)

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Article Chemistry, Medicinal

Targeted Delivery and Site-Specific Activation of β-Cyclodextrin-Conjugated Photosensitizers for Photodynamic Therapy through a Supramolecular Bio-orthogonal Approach

Evelyn Y. Xue et al.

Summary: This study presents a novel supramolecular bio-orthogonal approach to achieve targeted delivery and site-specific activation of photosensitizers, demonstrating its effectiveness and feasibility through a series of experiments in aqueous media, various cancer cell lines, and tumor-bearing nude mice.

JOURNAL OF MEDICINAL CHEMISTRY (2021)

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Article Chemistry, Organic

Synthesis and optical properties of 1-ethyl-indol-3-yl-substituted aza-BODIPY dyes at the 1,7-positions

Luis Loaeza et al.

Summary: Newly synthesized aza-BODIPYs exhibit significant red-shifted absorption, strong NIR absorption and emission, and large molar extinction coefficients in solution. The charge transfer from donor substituents towards the boron-centered core leads to the red-shifted absorption spectra, with HOMO-LUMO band gap values falling within the range of organic semiconductors.

TETRAHEDRON (2021)

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Article Biotechnology & Applied Microbiology

Highly stable organic photothermal agent based on near-infrared-II fluorophores for tumor treatment

Yunjian Xu et al.

Summary: By utilizing IPET and the steric relaxation effect, a class of stable NIR-II fluorophores with excellent emission and photothermal conversion performance have been successfully designed and synthesized. Among them, NIR998 NPs exhibit superior stability and photothermal conversion performance, showing great potential as photothermal agents in biological applications.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

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Article Chemistry, Multidisciplinary

Carbazole- and Fluorene-Fused Aza-BODIPYs: NIR Fluorophores with High Brightness and Photostability

Tanja Rappitsch et al.

Summary: Three new aza-BODIPY dyes with fused fluorene or carbazole moieties were prepared, showing significant enhancements in photophysical properties compared to the parent TPAB dye. These dyes exhibited a bathochromic shift in both absorption and emission maxima, increased molar absorption coefficients, and improved fluorescence quantum yield. The dyes are among the brightest NIR dyes reported and demonstrate excellent photostability, making them promising for further exploration in biomedical research. Additionally, a pH indicator with a fused carbazole unit was prepared, showing bathochromic shifts in absorption and emission spectra compared to the TPAB-based indicator dye.

CHEMISTRY-A EUROPEAN JOURNAL (2021)

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Article Engineering, Environmental

Rapid and visual detection of Cd2+ based on aza-BODIPY near infrared dye and its application in real and biological samples for environmental contamination screening

Pornthip Piyanuch et al.

Summary: A water-soluble near-infrared sensor based on aza-BODIPY was developed for dual determination of Cd2+ in environmental and biological media. The sensor showed rapid response, high sensitivity, and selectivity towards potentially interfering ions. It can be used to determine [Cd2+] in living cells and environmental samples.

JOURNAL OF HAZARDOUS MATERIALS (2021)

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Article Biochemical Research Methods

Overcoming Tumor Hypoxia through Multiple Pathways Using an All-in-One Polymeric Therapeutic Agent to Enhance Synergistic Cancer Photo/Chemotherapy Effects

Mingdang Li et al.

Summary: The study developed a polymeric therapeutic agent to overcome tumor hypoxia through multiple pathways, achieving capture and controllable release of O-1(2). It displayed promising synergistic anti-tumor and anti-recurrence efficacies under hypoxic environments, suggesting new avenues for the design of treatment platforms in clinical studies.

BIOCONJUGATE CHEMISTRY (2021)

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Article Engineering, Biomedical

Nitric oxide release activated near-Infrared photothermal agent for synergistic tumor treatment

Yunjian Xu et al.

Summary: An activatable multifunctional platform was designed to combine synergistic gas therapy and photothermal therapy by releasing nitric oxide (NO), showing enhanced heat production and tumor suppression effects. Water-soluble and biocompatible nanoparticles successfully improved the survival rate of mice under guidance of multimode imaging, offering rational guidance for designing better platforms for synergistic tumor treatments.

BIOMATERIALS (2021)

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Article Chemistry, Multidisciplinary

Near-infrared Aza-BODIPY Dyes Through Molecular Surgery for Enhanced Photothermal and Photodynamic Antibacterial Therapy

Qing Yu et al.

Summary: The study synthesized two near-infrared dyes with good biocompatibility in the form of nanoparticles, showing excellent photothermal conversion efficiency and reactive oxygen species production performance under 660 nm photoirradiation.

CHEMICAL RESEARCH IN CHINESE UNIVERSITIES (2021)

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Article Chemistry, Multidisciplinary

Aza-BODIPY based probe for photoacoustic imaging of ONOO- in vivo

Danghui Ma et al.

Summary: In this study, a novel photoacoustic probe AZB-1 was developed for in vivo imaging of ONOO-, and successfully applied in inflammatory mice models. By shutting the ICT effect, the output of its photoacoustic signal can be controlled, providing a potential platform for novel PA chemosensors.

CHINESE CHEMICAL LETTERS (2021)

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Review Chemistry, Inorganic & Nuclear

Recent developments of BODIPY-based colorimetric and fluorescent probes for the detection of reactive oxygen/nitrogen species and cancer diagnosis

Van-Nghia Nguyen et al.

Summary: Boron-dipyrromethene (BODIPY) platforms are versatile candidates for constructing fluorescent probes, playing a significant role in physiological processes and early cancer diagnosis. The continuous advancement in design and utilization of ROS/RNS fluorescent probes in recent years has contributed to reducing cancer-related deaths.

COORDINATION CHEMISTRY REVIEWS (2021)

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Article Chemistry, Inorganic & Nuclear

Tuning the Properties of Azadipyrromethene-Based Near-Infrared Dyes Using Intramolecular BO Chelation and Peripheral Substitutions

Jayvic C. Jimenez et al.

Summary: Tetraphenylazadipyrromethenes (ADPs) are promising near-infrared (NIR) dyes with potential applications in transparent solar cells and NIR photodetectors. By optimizing the coordination and substitutions, the properties of ADP complexes can be enhanced, making them suitable for organic electronic applications with low optical gap and high quantum yield.

INORGANIC CHEMISTRY (2021)

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Article Chemistry, Medicinal

Development of an Easily Bioconjugatable Water-Soluble Single-Photon Emission-Computed Tomography/Optical Imaging Bimodal Imaging Probe Based on the aza-BODIPY Fluorophore

Malorie Privat et al.

Summary: A water-soluble fluorescent aza-BODIPY platform was prepared and bioconjugated onto a trastuzumab monoclonal antibody to specifically label HER-2-positive breast tumors. The resulting bioconjugate showed stability in serum and was radiolabeled for in vivo studies, demonstrating good tumor targeting. The developed multimodal imaging probe displayed good quantum yield of fluorescence and near infrared emission, showing potential for fluorescence-guided surgery.

JOURNAL OF MEDICINAL CHEMISTRY (2021)

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Article Multidisciplinary Sciences

Activity-based photoacoustic probe for biopsy-free assessment of copper in murine models of Wilson's disease and liver metastasis

Melissa Y. Lucero et al.

Summary: The development of the high-performance photoacoustic probe PACu-1 shows promising potential for non-invasive assessment of hepatic Cu levels, showcasing successful detection of elevated Cu levels in disease models and successful differentiation of disease animals in blind studies.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

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Article Chemistry, Applied

A novel BODIPY-based reductant-sensitive near-infrared fluorescent probe for real-time reporting azoreductase-triggered release

Shuyuan Wang et al.

Summary: A novel NIR fluorescent probe ADP-Azo has been designed and synthesized for biological detection and drug delivery, with the ability to switch fluorescence on and off through the action of azoreductase. Drug-loaded micelles derived from ADP-Azo demonstrate efficient NIR fluorescence switch and drug release in a simulated colon environment.

REACTIVE & FUNCTIONAL POLYMERS (2021)

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Article Chemistry, Organic

NIR absorbing dimeric aza-BODIPY dye with J-type aggregation and photothermal properties

Dandan Tian et al.

Summary: A novel amphiphilic dimeric aza-BODIPY dye was synthesized and characterized, showing a bathochromically shifted absorption band and higher emission maximum compared to its precursor. The dimeric dye formed stable J-type aggregates and exhibited promising photothermal conversion efficiency.

TETRAHEDRON LETTERS (2021)

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Article Engineering, Biomedical

Rigidity Bridging Flexibility to Harmonize Three Excited-State Deactivation Pathways for NIR-II-Fluorescent-Imaging-Guided Phototherapy

Weijing Huang et al.

Summary: This study successfully developed CCNU-1060 nanoparticles with NIR-II fluorescence-guided phototherapeutic properties using a molecular design strategy. This approach enabled high-spatial vessel imaging and effective tumor ablation.

ADVANCED HEALTHCARE MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Development of pH-activatable fluorescent probes for rapid visualization of metastatic tumours and fluorescence-guided surgery via topical spraying

Xiaoxin Li et al.

Summary: A series of pH-activatable aza-BODIPY-based fluorescent probes have been developed for rapid cancer visualization and real-time fluorescence-guided surgery. Among them, AzaB5 with a pK(a) value of 6.7 can rapidly and clearly visualize pulmonary and abdominal metastatic tumours, including tiny metastases less than 2 mm, improving intraoperative fluorescence-guided resection.

CHEMICAL COMMUNICATIONS (2021)

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Article Chemistry, Analytical

A novel near-infrared colorimetric and fluorescent probe based on a piperidine-substituted aza-BODIPY photosensitizer for detection of extreme acidity

Jinfeng Zhou et al.

Summary: A novel NIR colorimetric and turn-on fluorescent pH probe (Probe 1) was designed and synthesized for detecting pH under extreme acidity, with the ability to visualize pH changes through color changes. The probe exhibited rapid response time, good stability, high specificity, and excellent recyclability. This work provides a new research platform for detecting strong acidity.

ANALYTICAL METHODS (2021)

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Article Materials Science, Biomaterials

A photo-triggered antifungal nanoplatform with efflux pump and heat shock protein reversal activity for enhanced chemo-photothermal synergistic therapy

Dongliang Yang et al.

Summary: The newly developed photo-triggered multifunctional nanoplatform can effectively eliminate drug-resistant fungi by releasing a quorum sensing molecule and an antifungal drug, and destroying the integrity of fungal cell membrane, inhibiting the expression of drug efflux pumps and heat shock proteins, and effectively blocking the hyphal and biofilm formation of fungi.

BIOMATERIALS SCIENCE (2021)

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Article Chemistry, Multidisciplinary

Panchromatic aza-Bodipy based π-conjugates

Thumuganti Gayathri et al.

Summary: Three aza-Bodipy donor molecules, Aza-Bthp, Aza-Sty, and Aza-Fhdt, have been synthesized, exhibiting broad panchromatic absorption and suitable energy levels for use in organic solar cells. Under optimized conditions, they achieved power conversion efficiencies of 2.44, 1.2, and 2.52 for Aza-Bthp, Aza-Fhdt, and Aza-Sty, respectively, when using PC70BM as an acceptor.

NEW JOURNAL OF CHEMISTRY (2021)

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Article Chemistry, Multidisciplinary

Aza-BODIPY encapsulated polymeric nanoparticles as an effective nanodelivery system for photodynamic cancer treatment

Jongjit Treekoon et al.

Summary: Polymeric nanoparticles loaded with aza-BODIPY were successfully prepared for targeted nanodelivery, exhibiting monodisperse spherical morphology. These nanoparticles showed significant therapeutic effects on breast cancer cells and demonstrated tumor growth inhibition in vivo.

MATERIALS CHEMISTRY FRONTIERS (2021)

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Article Chemistry, Multidisciplinary

A molecular design towards sulfonyl aza-BODIPY based NIR fluorescent and colorimetric probe for selective cysteine detection

Thanh Chung Pham et al.

Summary: A fluorescent probe, BDP-1, was developed for selective detection of cysteine, enabling early diagnosis of diseases. This probe exhibited color change and fluorescence enhancement upon reaction with cysteine, with a low detection limit.

RSC ADVANCES (2021)

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Article Materials Science, Multidisciplinary

Efficient electron transporting and panchromatic absorbing FRET cassettes based on aza-BODIPY and perylenediimide towards multiple metal FRET-Off sensing and ratiometric temperature sensing

Kavita Rani et al.

Summary: The multichromophoric triads 1 and 2 based on aza-BODIPY as the central chromophore and bay-substituted PDI as peripheral chromophores have shown excellent optical properties and electron transport performance. These triads can be used not only for FRET sensing, but also as efficient temperature sensors, providing the potential for precise physiological temperature measurements.

JOURNAL OF MATERIALS CHEMISTRY C (2021)

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Review Chemistry, Inorganic & Nuclear

Synthesis pathways for the preparation of the BODIPY analogues: aza-BODIPYs, BOPHYs and some other pyrrole-based acyclic chromophores

Liliya I. Shamova et al.

Summary: This review summarizes the synthesis strategies and post-functionalization methods for various compounds such as aza-BODIPYs, BOPHYs, etc.

DALTON TRANSACTIONS (2021)

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Article Biochemical Research Methods

3, 3,5 and 2,6 Expanded Aza-BODIPYs Via Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling Reactions: Synthesis and Photophysical Properties

Halil Yilmaz et al.

Summary: A series of novel symmetrical and unsymmetrical aza-BODIPY compounds were synthesized and characterized with various techniques, showing broad absorption in the near infrared region, high fluorescence quantum yield, and significant singlet oxygen generation capability. These compounds exhibit promising photophysical properties for applications in photodynamic therapy and organic photovoltaic cells in the NIR region.

JOURNAL OF FLUORESCENCE (2021)

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Article Chemistry, Multidisciplinary

Near-Infrared Laser-Triggered In Situ Dimorphic Transformation of BF2-Azadipyrromethene Nanoaggregates for Enhanced Solid Tumor Penetration

Yuanfang Chen et al.

ACS NANO (2020)

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Article Chemistry, Organic

Linker-Free Near-IR Aza-BODIPY-Glutamine Conjugates Through Boron Functionalization

Maodie Wang et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2020)

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Article Chemistry, Inorganic & Nuclear

Aza-BODIPY Platform: Toward an Efficient Water-Soluble Bimodal Imaging Probe for MRI and Near-Infrared Fluorescence

Oceane Flores et al.

INORGANIC CHEMISTRY (2020)

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Article Chemistry, Physical

Synthesis and photophysical properties of monomeric and dimeric halogenated aza-BODIPYs

H. Seyma Cinar et al.

JOURNAL OF MOLECULAR STRUCTURE (2020)

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Article Chemistry, Analytical

Pyrrolopyrrole aza-BODIPY dyes for ultrasensitive and highly selective biogenic diamine detection

Lanqing Li et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

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Article Nanoscience & Nanotechnology

Stable and Well-Organized Near-Infrared Platinum(II)-Acetylide-Based Metallacycles-Mediated Cancer Phototherapy

Guo Li et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Nanoscience & Nanotechnology

Aza-BODIPY-Based Nanomedicines in Cancer Phototheranostics

Dapeng Chen et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Biochemical Research Methods

Water-Soluble Aza-BODIPYs: Biocompatible Organic Dyes for High Contrast In Vivo NIR-II Imaging

Amelie Godard et al.

BIOCONJUGATE CHEMISTRY (2020)

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Article Polymer Science

Exploring NIR Aza-BODIPY-Based Polarity Sensitive Probes with ON-and-OFF Fluorescence Switching in Pluronic Nanoparticles

Bahar Saremi et al.

POLYMERS (2020)

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Article Chemistry, Applied

Donor-acceptor architectures of tetraphenylethene linked aza-BODIPYs: Synthesis, crystal structure, energy transfer and computational studies

Naresh Balsukuri et al.

DYES AND PIGMENTS (2020)

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Article Chemistry, Physical

Near-IR aza-BODIPY-based probe for the selective simultaneous detection of Cu2+ in aqueous buffer solutions and its application in biological samples

Panida Praikaew et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2020)

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Article Chemistry, Physical

Conductance Behavior of Tetraphenyl-Aza-BODIPYs

Andrei Markin et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2020)

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Article Chemistry, Multidisciplinary

Red/NIR Thermally Activated Delayed Fluorescence from Aza-BODIPYs

Edurne Avellanal-Zaballa et al.

CHEMISTRY-A EUROPEAN JOURNAL (2020)

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Article Chemistry, Applied

Methotrexate coated AZA-BODIPY nanoparticles for chemotherapy, photothermal and photodynamic synergistic therapy

Ruonan Li et al.

DYES AND PIGMENTS (2020)

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Article Chemistry, Applied

Near-infrared fluorescent amphiphilic Aza-BODIPY dye: Synthesis, solvatochromic properties, and selective detection of Cu2+

Jiahe Zuo et al.

DYES AND PIGMENTS (2020)

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Article Biochemistry & Molecular Biology

Synthesis and In Vitro Photodynamic Activity of Cationic Boron Dipyrromethene-Based Photosensitizers Against Methicillin-Resistant Staphylococcus aureus

Priyanga Dharmaratne et al.

BIOMEDICINES (2020)

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Article Chemistry, Physical

Synthesis and Characterization of Push-Pull Aza-BODIPY Dyes Towards Application in NIR-II Photothermal Therapy

Sopita Rattanopas et al.

CHEMPHOTOCHEM (2020)

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Article Biochemical Research Methods

Optical ammonia sensors based on fluorescent aza-BODIPY dyes- a flexible toolbox

Maximilian Maierhofer et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2020)

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Article Biochemistry & Molecular Biology

NIR Absorbing AzaBODIPY Dyes for pH Sensing

Gugu Kubheka et al.

MOLECULES (2020)

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Review Chemistry, Inorganic & Nuclear

Recent advances of BODIPY based derivatives for optoelectronic applications

Madhurima Poddar et al.

COORDINATION CHEMISTRY REVIEWS (2020)

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Article Chemistry, Multidisciplinary

Synthesis, characterization, and tunable semiconducting properties of aza-BODIPY derived polycyclic aromatic dyes

Wanle Sheng et al.

SCIENCE CHINA-CHEMISTRY (2020)

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Article Chemistry, Multidisciplinary

Surfactant-stripped J-aggregates of azaBODIPY derivatives: All-in-one phototheranostics in the second near infrared window

Yicheng Zhang et al.

JOURNAL OF CONTROLLED RELEASE (2020)

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Article Chemistry, Physical

High-Performance Optical Power Limiting Filters at Telecommunication Wavelengths: When Aza-BODIPY Dyes Bond to Sol-Gel Materials

Sylvain David et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2020)

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Article Materials Science, Biomaterials

A photothermally-induced HClO-releasing nanoplatform for imaging-guided tumor ablation and bacterial prevention

Menglong Zhao et al.

BIOMATERIALS SCIENCE (2020)

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Review Chemistry, Multidisciplinary

Bioapplications of small molecule Aza-BODIPY: from rational structural design to in vivo investigations

Zhenxiong Shi et al.

CHEMICAL SOCIETY REVIEWS (2020)

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Review Nanoscience & Nanotechnology

Rational Design of Ratiometric Near-Infrared Aza-BODIPY-Based Fluorescent Probe for in Vivo Imaging of Endogenous Hydrogen Peroxide

Wenle Mao et al.

ACS APPLIED BIO MATERIALS (2020)

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Article Chemistry, Multidisciplinary

Self-assembled star-shaped aza-BODIPY mesogen affords white-light emission

Chao Liu et al.

NEW JOURNAL OF CHEMISTRY (2020)

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Article Materials Science, Multidisciplinary

Near-infrared absorbing pyrrolopyrrole aza-BODIPY-based donor-acceptor polymers with reasonable photoresponse

Ru Feng et al.

JOURNAL OF MATERIALS CHEMISTRY C (2020)

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Article Polymer Science

Real-time near-infrared fluorescence reporting the azoreductase-triggered drug release

Yuqing Wang et al.

POLYMER CHEMISTRY (2020)

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Review Chemistry, Multidisciplinary

Assembly strategies of organic-based imaging agents for fluorescence and photoacoustic bioimaging applications

Hong-Bo Cheng et al.

CHEMICAL SOCIETY REVIEWS (2020)

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Article Chemistry, Multidisciplinary

Hydrogen Sulfide-Specific and NIR-Light-Controllable Synergistic Activation of Fluorescent Theranostic Prodrugs for Imaging-Guided Chemo-Photothermal Cancer Therapy

Ge Xu et al.

CCS CHEMISTRY (2020)

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Article Chemistry, Applied

Near-infrared nanoparticles based on aza-BDP for photodynamic and photothermal therapy

Yang Liu et al.

DYES AND PIGMENTS (2019)

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Article Construction & Building Technology

High-resolution optical pH imaging of concrete exposed to chemically corrosive environments

Cyrill Grengg et al.

CEMENT AND CONCRETE RESEARCH (2019)

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Article Chemistry, Multidisciplinary

Synthesis of aza-BODIPY dyes bearing the naphthyl groups at 1,7-positions and application for singlet oxygen generation

Xindong Jiang et al.

CHINESE CHEMICAL LETTERS (2019)

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Article Chemistry, Physical

Aggregation-Induced Emission Materials with Narrowed Emission Band by Light-Harvesting Strategy: Fluorescence and Chemiluminescence Imaging

Xin Zhu et al.

CHEMISTRY OF MATERIALS (2019)

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Article Chemistry, Multidisciplinary

Stable J-Aggregation of an aza-BODIPY-Lipid in a Liposome for Optical Cancer Imaging

Miffy H. Y. Cheng et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Article Chemistry, Medicinal

Rational Design of Efficient Organic Phototherapeutic Agents via Perturbation Theory for Enhancing Anticancer Therapeutics

Yunjian Xu et al.

CHEMMEDCHEM (2019)

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Review Chemistry, Inorganic & Nuclear

Unadulterated BODIPY nanoparticles for biomedical applications

Tao Zhang et al.

COORDINATION CHEMISTRY REVIEWS (2019)

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Article Engineering, Biomedical

Facile Phototherapeutic Nanoplatform by Integrating a Multifunctional Polymer and MnO2 for Enhancing Tumor Synergistic Therapy

Menglong Zhao et al.

ADVANCED HEALTHCARE MATERIALS (2019)

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Article Chemistry, Multidisciplinary

Manipulating Nonradiative Decay Channel by Intermolecular Charge Transfer for Exceptionally Improved Photothermal Conversion

Wenbo Hu et al.

ACS NANO (2019)

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Article Chemistry, Organic

Monofunctionalized 1,3,5,7-TetraarylazaBODIPYs and Their Application in the Synthesis of AzaBODIPY Based Conjugates

Angira Koch et al.

JOURNAL OF ORGANIC CHEMISTRY (2019)

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Article Chemistry, Physical

Unraveling the Two-Photon and Excited-State Absorptions of Aza-BODIPY Dyes for Optical Power Limiting in the SWIR Band

Simon Pascal et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2019)

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Article Chemistry, Organic

Synthesis and application of near-infrared absorbing morpholino-containing aza-BODIPYs

Xin-Dong Jiang et al.

TETRAHEDRON (2019)

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Article Engineering, Biomedical

Photothermal-pH-hypoxia responsive multifunctional nanoplatform for cancer photo-chemo therapy with negligible skin phototoxicity

Dapeng Chen et al.

BIOMATERIALS (2019)

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Article Biochemistry & Molecular Biology

Water soluble thioglycosylated BODIPYs for mitochondria targeted cytotoxicity

Praseetha E. Kesavan et al.

BIOORGANIC CHEMISTRY (2019)

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Article Chemistry, Multidisciplinary

A Conformationally Restricted Aza-BODIPY Platform for Stimulus-Responsive Probes with Enhanced Photoacoustic Properties

Effie Y. Zhou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

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Article Spectroscopy

A reactive turn-on fluorescence probe for hypochlorous acid and its bioimaging application

Yunling Gao et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2019)

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Article Chemistry, Multidisciplinary

A Near-Infrared Fluorescence Chemosensor Based on Isothiocyanate-Aza-BODIPY for Cyanide Detection at the Parts per Billion Level: Applications in Buffer Media and Living Cell Imaging

Pornthip Piyanuch et al.

CHEMPLUSCHEM (2019)

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Review Chemistry, Multidisciplinary

Carbazole Substituted BODIPYs

Iti Gupta et al.

FRONTIERS IN CHEMISTRY (2019)

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Article Chemistry, Multidisciplinary

Butterfly architecture of NIR Aza-BODIPY small molecules decorated with phenothiazine or phenoxazine

Ravulakollu Srinivasa Rao et al.

CHEMICAL COMMUNICATIONS (2019)

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Article Chemistry, Multidisciplinary

Oxygen self-sufficient NIR-activatable liposomes for tumor hypoxia regulation and photodynamic therapy

Qi Yu et al.

CHEMICAL SCIENCE (2019)

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Review Materials Science, Multidisciplinary

Recent advances in the application of BODIPY in bioimaging and chemosensing

Paramjit Kaur et al.

JOURNAL OF MATERIALS CHEMISTRY C (2019)

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Article Materials Science, Biomaterials

Imaging of anti-inflammatory effects of HNO via a near-infrared fluorescent probe in cells and in rat gouty arthritis model

Yan Huang et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

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Article Chemistry, Multidisciplinary

Intelligent polymer-MnO2 nanoparticles for dual-activatable photoacoustic and magnetic resonance bimodal imaging in living mice

Xiaoming Hu et al.

CHEMICAL COMMUNICATIONS (2019)

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Article Chemistry, Multidisciplinary

Aza-BODIPY probe for selective visualization of cyclooxygenase-2 in cancer cells

Thitima Pewklang et al.

RSC ADVANCES (2019)

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Article Chemistry, Multidisciplinary

A fluorinated aza-BODIPY derivative for NIR fluorescence/PA/19F MR tri-modality in vivo imaging

Lianhua Liu et al.

CHEMICAL COMMUNICATIONS (2019)

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Article Chemistry, Multidisciplinary

Novel aza-BODIPY based small molecular NIR-II fluorophores for in vivo imaging

Lei Bai et al.

CHEMICAL COMMUNICATIONS (2019)

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Article Chemistry, Analytical

Near-infrared fluorescent aza-BODIPY dyes for sensing and imaging of pH from the neutral to highly alkaline range

Christoph Staudinger et al.

ANALYST (2019)

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Article Chemistry, Multidisciplinary

A highly efficient, colorimetric and fluorescent probe for recognition of aliphatic primary amines based on a unique cascade chromophore reaction

Lanqing Li et al.

CHEMICAL COMMUNICATIONS (2019)

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Article Nanoscience & Nanotechnology

Smart Aza-BODIPY Photosensitizer for Tumor Microenvironment-Enhanced Cancer Phototherapy

Yunyun Tang et al.

ACS APPLIED BIO MATERIALS (2019)

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Article Chemistry, Multidisciplinary

Deciphering the intersystem crossing in near-infrared BODIPY photosensitizers for highly efficient photodynamic therapy

Xiaofei Miao et al.

CHEMICAL SCIENCE (2019)

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Article Medicine, Research & Experimental

Molecular Engineering of Near-Infrared Light-Responsive BODIPY-Based Nanoparticles with Enhanced Photothermal and Photoacoustic Efficiencies for Cancer Theranostics

Duyang Gao et al.

THERANOSTICS (2019)

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Article Biochemistry & Molecular Biology

Photophysical Tuning of N-Oxide-Based Probes Enables Ratiometric Photoacoustic Imaging of Tumor Hypoxia

Hailey J. Knox et al.

ACS CHEMICAL BIOLOGY (2018)

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Article Chemistry, Physical

Damage-Responsive Microcapsules for Amplified Photoacoustic Detection of Microcracks in Polymers

JunLong Geng et al.

CHEMISTRY OF MATERIALS (2018)

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Article Chemistry, Applied

Synthesis and acid-responsive spectral properties of near-infrared-absorbing donor-π-donor-type aza boron dipyrromethenes

Wen-Jing Shi et al.

DYES AND PIGMENTS (2018)

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Article Chemistry, Organic

1,7-Difluorophore-Substituted AzaBODIPYs

Angira Koch et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2018)

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Article Chemistry, Multidisciplinary

Near infra-red dyes based on pyrene aza-BODIPYs

Naresh Balsukuri et al.

NEW JOURNAL OF CHEMISTRY (2018)

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Article Polymer Science

Synthesis of a near-infrared light-absorbing polymer based on thiophene-substituted Aza-BODIPY

Honami Yamane et al.

POLYMER JOURNAL (2018)

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Article Chemistry, Analytical

A fast-response, red emission aza-BODIPY-hydrazone-based chemodosimeter for selective detection of HClO

Yuling Gao et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

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Article Engineering, Biomedical

pH-Responsive PEG-Doxorubicin-Encapsulated Aza-BODIPY Nanotheranostic Agent for Imaging-Guided Synergistic Cancer Therapy

Dapeng Chen et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Article Materials Science, Biomaterials

Functional aza-boron dipyrromethenes for subcellular imaging and organelle-specific photodynamic therapy

Qiong Wang et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Article Materials Science, Biomaterials

Enhancing hydrophilicity of photoacoustic probes for effective ratiometric imaging of hydrogen peroxide

Xiaomei Lu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Article Engineering, Biomedical

2-Pyridone-functionalized Aza-BODIPY photosensitizer for imaging-guided sustainable phototherapy

Wanyue Xiao et al.

BIOMATERIALS (2018)

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Article Chemistry, Multidisciplinary

Coupled Cooperative Supramolecular Polymerization: A New Model Applied to the Competing Aggregation Pathways of an Amphiphilic aza-BODIPY Dye into Spherical and Rod-Like Aggregates

Yong Liu et al.

CHEMISTRY-A EUROPEAN JOURNAL (2018)

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Article Chemistry, Organic

Covalently Linked meso-BODIPYnyl Dithiahomoporphyrins: Synthesis and Properties

Kishor G. Thorat et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2018)

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Article Chemistry, Multidisciplinary

Near-Infrared Photoactivatable Nitric Oxide Donors with Integrated Photoacoustic Monitoring

Effie Y. Zhou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

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Article Engineering, Biomedical

Halogenated Aza-BODIPY for Imaging-Guided Synergistic Photodynamic and Photothermal Tumor Therapy

Menglong Zhao et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Review Chemistry, Multidisciplinary

Acoustogenic Probes: A New Frontier in Photoacoustic Imaging

Hailey J. Knox et al.

ACCOUNTS OF CHEMICAL RESEARCH (2018)

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Highly Stable and Multifunctional Aza-BODIPY-Based Phototherapeutic Agent for Anticancer Treatment

Yunjian Xu et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Rational design of near-infrared dyes based on boron dipyrromethene derivatives for application in organic solar cells

Man Zhang et al.

RSC ADVANCES (2018)

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Aza-BODIPY based polymeric nanoparticles for cancer cell imaging

Kantapat Chansaenpak et al.

RSC ADVANCES (2018)

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Blackening of aza-BODIPY analogues by simple dimerization: panchromatic absorption of a pyrrolopyrrole aza-BODIPY dimer

Yuto Kage et al.

MATERIALS CHEMISTRY FRONTIERS (2018)

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Novel Small Molecule Probes for Metastatic Melanoma

Anyanee Kamkaew et al.

ACS MEDICINAL CHEMISTRY LETTERS (2017)

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Observation of the Strong Electronic Coupling in Near-Infrared-Absorbing Tetraferrocene aza-Dipyrromethene and aza-BODIPY with Direct Ferrocene-α- and Ferrocene-β-Pyrrole Bonds: Toward Molecular Machinery with Four-Bit Information Storage Capacity

Yuriy V. Zatsikha et al.

INORGANIC CHEMISTRY (2017)

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Synthesis and Properties of Covalently Linked AzaBODIPY-BODIPY Dyads and AzaBODIPY-(BODIPY)2 Triads

Sunit Kumar et al.

JOURNAL OF ORGANIC CHEMISTRY (2017)

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New wavelength-tunable aza-dipyrromethene dyes with intense near-infrared absorption and emission

Emad M. A. Al-Imarah et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2017)

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Photosensitizer localization in amphiphilic block copolymers controls photodynamic therapy efficacy

Vusala Ibrahimova et al.

NANOSCALE (2017)

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Photophysics and redox properties of aza-BODIPY dyes with electron-withdrawing groups

Arkadiusz Gut et al.

NEW JOURNAL OF CHEMISTRY (2017)

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Copper(II)-promoted oxidative C-H/C-H cross-coupling for rapid access to aza-BODIPY-indole derivatives with broad optical absorption

Ruyong Jiang et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2017)

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Heck functionalization of an asymmetric aza-BODIPY core: synthesis of far-red infrared probes for bioimaging applications

Stefano Parisotto et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2017)

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Photostable upconverting and downconverting pH sensors based on combination of a colorimetric NIR indicator and stable inorganic phosphors as secondary emitters

Martin Strobl et al.

SENSORS AND ACTUATORS B-CHEMICAL (2017)

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Use of Wittig reaction for the synthesis of conjugated Aza-BODIPYs and their spectral and electrochemical properties

Angira Koch et al.

TETRAHEDRON (2017)

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Synthesis of furan-substituted aza-BODIPYs having near-infrared emission

Honami Yamane et al.

TETRAHEDRON LETTERS (2017)

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Addressing the autofluorescence issue in deep tissue imaging by two-photon microscopy: the significance of far-red emitting dyes

Yong Woong Jun et al.

CHEMICAL SCIENCE (2017)

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An agent for optical imaging of TrkC-expressing, breast cancer

Anyanee Kamkaew et al.

MEDCHEMCOMM (2017)

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A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia

Hailey J. Knox et al.

NATURE COMMUNICATIONS (2017)

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Tetraphenylethylene- and fluorene-functionalized near-infrared aza-BODIPY dyes for living cell imaging

Li Zhu et al.

RSC ADVANCES (2017)

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An aza-BODIPY photosensitizer for photoacoustic and photothermal imaging guided dual modal cancer phototherapy

Qianyun Tang et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

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Highly Efficient Solid-State Near-infrared Organic Light-Emitting Diodes incorporating A-D-A Dyes based on α,β-unsubstituted BODIPY Moieties

Andrea Zampetti et al.

SCIENTIFIC REPORTS (2017)

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Synthesis, structure and photophysical properties of NIR aza-BODIPYs with -F/-N3/NH2 groups at 1,7-positions

Xin-Dong Jiang et al.

DYES AND PIGMENTS (2017)

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Near-infrared aza-BODIPY fluorescent probe for selective Cu2+ detection and its potential in living cell imaging

Yordkhuan Tachapermpon et al.

DALTON TRANSACTIONS (2017)

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BODIPYs for Dye-Sensitized Solar Cells

Hafsah Klfout et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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Synthesis and application of methylthio-substituted BODIPYs/ aza-BODIPYs

Xin-Dong Jiang et al.

DYES AND PIGMENTS (2017)

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A facile synthesis of novel near-infrared pyrrolopyrrole aza-BODIPY luminogens with aggregation-enhanced emission characteristics

Lanqing Li et al.

CHEMICAL COMMUNICATIONS (2017)

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pH-Triggered and Enhanced Simultaneous Photodynamic and Photothermal Therapy Guided by Photoacoustic and Photothermal Imaging

Qianyun Tang et al.

CHEMISTRY OF MATERIALS (2017)

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Carbazole-Linked Near-Infrared Aza-BODIPY Dyes as Triplet Sensitizers and Photoacoustic Contrast Agents for Deep-Tissue Imaging

Yogesh Gawale et al.

CHEMISTRY-A EUROPEAN JOURNAL (2017)

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An aza-BODIPY based near-infrared fluorescent probe for sensitive discrimination of cysteine/homocysteine and glutathione in living cells

Hui-Jing Xiang et al.

CHEMICAL COMMUNICATIONS (2017)

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Trace Ammonia Sensors Based on Fluorescent Near-Infrared Emitting aza-BODIPY Dyes

Martin Strobl et al.

ANALYTICAL CHEMISTRY (2017)

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Highly sensitive poisoning-resistant optical carbon dioxide sensors for environmental monitoring

Eva Fritzsche et al.

ANALYTICAL METHODS (2017)

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In Vivo Tracking of Phagocytic Immune Cells Using a Dual Imaging Probe with Gadolinium-Enhanced MRI and Near-Infrared Fluorescence

Eun-Joong Kim et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

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Synthesis of covalently bonded boron-dipyrromethene-diarylethene for building a stable photosensitizer with photo-controlled reversibility

Qiao-Ju Hu et al.

CHEMICAL COMMUNICATIONS (2016)

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Azadipyrromethenes: from traditional dye chemistry to leading edge applications

Yuan Ge et al.

CHEMICAL SOCIETY REVIEWS (2016)

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Rational Design of Emissive NIR-Absorbing Chromophores: RhIII Porphyrin-Aza-BODIPY Conjugates with Orthogonal Metal-Carbon Bonds

Jinfeng Zhou et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

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Synthesis, Electrochemistry, and Photophysics of Aza-BODIPY Porphyrin Dyes

Simon Pascal et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

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Synthesis, Structure, and Optical Studies of Donor-Acceptor-Type Near-Infrared (NIR) Aza-Boron-Dipyrromethene (BODIPY) Dyes

Naresh Balsukuri et al.

CHEMISTRY-AN ASIAN JOURNAL (2016)

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Chiral benzo-fused Aza-BODIPYs with optical activity extending into the NIR range

Lu Zhang et al.

DYES AND PIGMENTS (2016)

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Synthesis of NIR fluorescent thienyl-containing aza-BODIPY and its application for detection of Hg2+: Electron transfer by bonding with Hg2+

Xin-Dong Jiang et al.

DYES AND PIGMENTS (2016)

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Near-infrared fluorescent aza-BODIPY dye-loaded biodegradable polymeric nanoparticles for optical cancer imaging

Casey L. Hamon et al.

JOURNAL OF NANOPARTICLE RESEARCH (2016)

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Ferrocenyl aza-dipyrromethene and aza-BODIPY: Synthesis and properties

Rekha Sharma et al.

JOURNAL OF ORGANOMETALLIC CHEMISTRY (2016)

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Donor acceptor type ferrocene substituted aza-BODIPYs: Synthesis, optical and electrochemical studies

Naresh Balsukuri et al.

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES (2016)

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Bioimaging of Intravenous Polymeric Micelles Based on Discrimination of Integral Particles Using an Environment-Responsive Probe

Haisheng He et al.

MOLECULAR PHARMACEUTICS (2016)

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Synthesis, structure and properties of thiophene-fused BODIPYs and azaBODIPYs as near-infrared agents

Jun Wang et al.

NEW JOURNAL OF CHEMISTRY (2016)

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Singlet oxygen generation properties of isometrically dibromated thienyl-containing aza-BODIPYs

Xin-Dong Jiang et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2016)

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Nucleophilic addition of CN- ion to -C=N bond of aza-BODIPY leading to turn-on fluorescence sensor

Avanish Dvivedi et al.

SENSORS AND ACTUATORS B-CHEMICAL (2016)

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Revealing a nucleophilic addition reaction between aza-BODIPY and cyanide anion

Fei Wu et al.

TETRAHEDRON LETTERS (2016)

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Highly efficient near IR photosensitizers based-on Ir-C bonded porphyrin-aza-BODIPY conjugates

Jinfeng Zhou et al.

RSC ADVANCES (2016)

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Synthesis and photophysical properties of orthogonal rhodium(III)-carbon bonded porphyrin-aza-BODIPY conjugates

Jinfeng Zhou et al.

JOURNAL OF MATERIALS CHEMISTRY C (2016)

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High-Resolution Ultrasound-Switchable Fluorescence Imaging in Centimeter-Deep Tissue Phantoms with High Signal-To-Noise Ratio and High Sensitivity via Novel Contrast Agents

Bingbing Cheng et al.

PLOS ONE (2016)

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A near IR photosensitizer based on self-assembled CdSe quantum dot-aza-BODIPY conjugate coated with poly(ethylene glycol) and folic acid for concurrent fluorescence imaging and photodynamic therapy

Yu Yan et al.

RSC ADVANCES (2016)

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Boronic Acid Functionalized Aza-Bodipy (azaBDPBA) based Fluorescence Optodes for the Analysis of Glucose in Whole Blood

Yueling Liu et al.

ACS APPLIED MATERIALS & INTERFACES (2015)

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A near-infrared fluorescent probe for the selective detection of HNO in living cells and in vivo

Ping Liu et al.

ANALYST (2015)

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NIR-emitting aza-BODIPY dyes - new building blocks for broad-range optical pH sensors

Martin Strobl et al.

ANALYST (2015)

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Asymmetric core-expanded aza-BODIPY analogues: facile synthesis and optical properties

Hui Liu et al.

CHEMICAL COMMUNICATIONS (2015)

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Chromogenic/Fluorogenic Ensemble Chemosensing Systems

Jiasheng Wu et al.

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Molecular Interactions in Organic Nanoparticles for Phototheranostic Applications

Kenneth K. Ng et al.

CHEMICAL REVIEWS (2015)

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BODIPY-based probes for the fluorescence imaging of biomolecules in living cells

Toshiyuki Kowada et al.

CHEMICAL SOCIETY REVIEWS (2015)

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Benzo[c,d]indole-Containing Aza-BODIPY Dyes: Asymmetrization-Induced Solid-State Emission and Aggregation-Induced Emission Enhancement as New Properties of a Well-Known Chromophore

Soji Shimizu et al.

CHEMISTRY-A EUROPEAN JOURNAL (2015)

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The effect of heavy atom to two photon absorption properties and intersystem crossing mechanism in aza-boron-dipyrromethene compounds

Ahmet Karatay et al.

DYES AND PIGMENTS (2015)

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Panchromatic Borane-aza-BODIPY Conjugate: Synthesis, Intriguing Optical Properties, and Selective Fluorescent Sensing of Fluoride Anions

Chinna Ayya Swamy P et al.

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (2015)

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Synthesis and Charge-Transfer Dynamics in a Ferrocene-Containing Organoboryl aza-BODIPY Donor-Acceptor Triad with Boron as the Hub

Eranda Maligaspe et al.

INORGANIC CHEMISTRY (2015)

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Photoacoustic Probes for Ratiometric Imaging of Copper(II)

Hao Li et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

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Oligoethylene glycol-substituted aza-BODIPY dyes as red emitting ER-probes

Anyanee Kamkaew et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2015)

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Synthesis of NIR naphthyl-containing aza-BODIPYs and measure of the singlet oxygen generation

Xin-Dong Jiang et al.

TETRAHEDRON (2015)

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Synthesis and properties of hexaarylated AzaBODIPYs

Sunit Kumar et al.

TETRAHEDRON (2015)

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Synthesis of a pyrene-fused aza-BODIPY as a near-infrared dye having the absorption maximum at 746 nm

Xin-Dong Jiang et al.

TETRAHEDRON LETTERS (2015)

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A pH-activatable and aniline-substituted photosensitizer for near-infrared cancer theranostics

Jiangwei Tian et al.

CHEMICAL SCIENCE (2015)

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NIR optical carbon dioxide sensors based on highly photostable dihydroxy-aza-BODIPY dyes

Susanne Schutting et al.

JOURNAL OF MATERIALS CHEMISTRY C (2015)

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Rational Molecular Design towards Vis/NIR Absorption and Fluorescence by using Pyrrolopyrrole aza-BODIPY and its Highly Conjugated Structures for Organic Photovoltaics

Soji Shimizu et al.

CHEMISTRY-A EUROPEAN JOURNAL (2015)

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Synthesis, characterization and photophysical properties of an acenaphthalene fused-ring-expanded NIR absorbing aza-BODIPY dye

Poulomi Majumdar et al.

RSC ADVANCES (2015)

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Hydroxylated near-infrared BODIPY fluorophores as intracellular pH sensors

Mohamed M. Salim et al.

ANALYST (2014)

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Sensitive Naked Eye Detection of Hydrogen Sulfide and Nitric Oxide by Aza-BODIPY Dyes in Aqueous Medium

Nagappanpillai Adarsh et al.

ANALYTICAL CHEMISTRY (2014)

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Synthesis and optophysical properties of dimeric aza-BODIPY dyes with a push-pull benzodipyrrolidone core

Yafei Wang et al.

CHEMICAL COMMUNICATIONS (2014)

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Visualization of nitroxyl (HNO) in vivo via a lysosome-targetable near-infrared fluorescent probe

Xiaotong Jing et al.

CHEMICAL COMMUNICATIONS (2014)

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Structural modification strategies for the rational design of red/NIR region BODIPYs

Hua Lu et al.

CHEMICAL SOCIETY REVIEWS (2014)

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A class of wavelength-tunable near-infrared aza-BODIPY dyes and their application for sensing mercury ion

Shujuan Liu et al.

DYES AND PIGMENTS (2014)

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Synthesis of a Class of Core-Modified Aza-BODIPY Derivatives

Alejandro Diaz-Moscoso et al.

JOURNAL OF ORGANIC CHEMISTRY (2014)

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Accessing Near-Infrared-Absorbing BF2-Azadipyrromethenes via a Push-Pull Effect

Lijuan Jiao et al.

JOURNAL OF ORGANIC CHEMISTRY (2014)

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β-Thiophene-Fused BF2-Azadipyrromethenes as Near-Infrared Dyes

Yayang Wu et al.

ORGANIC LETTERS (2014)

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PEGylated aza-BODIPY derivatives as NIR probes for cellular imaging

Daniel Collado et al.

RSC ADVANCES (2014)

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A styryl-containing aza-BODIPY as a near-infrared dye

Xin-Dong Jiang et al.

RSC ADVANCES (2014)

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A new aza-BODIPY based NIR region colorimetric and fluorescent chemodosimeter for fluoride

Bin Zou et al.

RSC ADVANCES (2014)

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Photoredox catalytic organic reactions promoted with broadband visible light-absorbing Bodipy-iodo-aza-Bodipy triad photocatalyst

Song Guo et al.

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A versatile approach for ratiometric time-resolved read-out of colorimetric chemosensors using broadband phosphors as secondary emitters

Sergey M. Borisov et al.

ANALYTICA CHIMICA ACTA (2013)

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New Life of Ancient Pigments: Application in High-Performance Optical Sensing Materials

Sergey M. Borisov et al.

ANALYTICAL CHEMISTRY (2013)

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Efficient Reaction Based Colorimetric Probe for Sensitive Detection, Quantification, and On-Site Analysis of Nitrite Ions in Natural Water Resources

Nagappanpillai Adarsh et al.

ANALYTICAL CHEMISTRY (2013)

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Formation and photoinduced processes of the host-guest complexes of a β-cyclodextrin-conjugated aza-BODIPY and tetrasulfonated porphyrins

Wen-Jing Shi et al.

CHEMICAL COMMUNICATIONS (2013)

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Energy transfer cassettes based on organic fluorophores: construction and applications in ratiometric sensing

Jiangli Fan et al.

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BODIPY dyes in photodynamic therapy

Anyanee Kamkaew et al.

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Enhancement of two photon absorption properties by charge transfer in newly synthesized aza-boron-dipyrromethene compounds containing triphenylamine, 4-ethynyl-N,N-dimethylaniline and methoxy moieties

Sezen Tekin et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2013)

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pH-Sensitive Fluorescent Dyes: Are They Really pH-Sensitive in Cells?

Xiao-Xiang Zhang et al.

MOLECULAR PHARMACEUTICS (2013)

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New insights into two-photon absorption properties of functionalized aza-BODIPY dyes at telecommunication wavelengths: a theoretical study

Xiaoting Liu et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2013)

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Near-infrared emission of novel bent-core V-shaped conjugated polymers based on the B,O-chelated azadipyrromethene structure

Xiao Ma et al.

POLYMER CHEMISTRY (2013)

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Boron-Fluorine Photosensitizers for Photodynamic Therapy

Liang Yao et al.

JOURNAL OF CHEMISTRY (2013)

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Highly Photostable Near-Infrared Fluorescent pH Indicators and Sensors Based on BF2-Chelated Tetraarylazadipyrromethene Dyes

Tijana Jokic et al.

ANALYTICAL CHEMISTRY (2012)

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Aza-BODIPY Derivatives: Enhanced Quantum Yields of Triplet Excited States and the Generation of Singlet Oxygen and their Role as Facile Sustainable Photooxygenation Catalysts

Nagappanpillai Adarsh et al.

CHEMISTRY-A EUROPEAN JOURNAL (2012)

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Near-IR Excitation Transfer and Electron Transfer in a BF2-Chelated Dipyrromethane-Azadipyrromethane Dyad and Triad

Mohamed E. El-Khouly et al.

CHEMISTRY-A EUROPEAN JOURNAL (2012)

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Replacing Phenyl Ring with Thiophene: An Approach to Longer Wavelength Aza-dipyrromethene Boron Difluoride (Aza-BODIPY) Dyes

Xinfu Zhang et al.

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Synthesis, optical properties and ultrafast dynamics of aza-boron-dipyrromethene compounds containing methoxy and hydroxy groups and two-photon absorption cross-section

Betul Kucukoz et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY (2012)

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Control over Photoinduced Energy and Electron Transfer in Supramolecular Polyads of Covalently linked azaBODIPY-Bisporphyrin 'Molecular Clip' Hosting Fullerene

Francis D'Souza et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

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Thiophene-substituted aza-bodipy as a strategic synthon for the design of near-infrared dyes

Quentin Bellier et al.

NEW JOURNAL OF CHEMISTRY (2012)

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A selective fluorescent turn-on NIR probe for cysteine

Xin-Dong Jiang et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2012)

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Ion-selective optodes based on near infrared fluorescent chromoionophores for pH and metal ion measurements

Yifan Ge et al.

SENSORS AND ACTUATORS B-CHEMICAL (2012)

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Synthesis and properties of NIR aza-BODIPYs with aryl and alkynyl substituents on the boron center

Xin-Dong Jiang et al.

TETRAHEDRON LETTERS (2012)

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A selective colorimetric and fluorometric ammonium ion sensor based on the H-aggregation of an aza-BODIPY with fused pyrazine rings

Hanzhuang Liu et al.

CHEMICAL COMMUNICATIONS (2011)

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Synthesis and Characterization of Near-Infrared Absorbing Benzannulated Aza-BODIPY Dyes

Roland Gresser et al.

CHEMISTRY-A EUROPEAN JOURNAL (2011)

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Synthesis and Spectroscopic Properties of Fused-Ring-Expanded Aza-Boradiazaindacenes

Hua Lu et al.

CHEMISTRY-AN ASIAN JOURNAL (2011)

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Synthesis, Photophysical, Electrochemical, and Electrogenerated Chemiluminescence Studies. Multiple Sequential Electron Transfers in BODIPY Monomers, Dinners, Trimers, and Polymer

Alexander B. Nepomnyashchii et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

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Azadipyrromethene-Based Conjugated Oligomers with Near-IR Absorption and High Electron Affinity

Lei Gao et al.

ORGANIC LETTERS (2011)

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Near-Infrared Nitrofluorene Substitued Aza-Boron-dipyrromethenes Dyes

Quenlin Bellier et al.

ORGANIC LETTERS (2011)

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Synthesis of thiophene-substituted aza-BODIPYs and their optical and electrochemical properties

Roland Gresser et al.

TETRAHEDRON (2011)

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Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

Jonathan P. Celli et al.

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Intramolecular Excitation Energy Transfer from Visible-light Absorbing Chlorophyll Derivatives to a Near-infrared-light Emitting Boron Dipyrromethene Moiety

Yumiko Kataoka et al.

CHEMISTRY LETTERS (2010)

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Highly Near-Infrared Photoluminescence from Aza-Borondipyrromethene-Based Conjugated Polymers

Ryousuke Yoshii et al.

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY (2010)

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Tuning Photosensitized Singlet Oxygen Generation Efficiency of Novel Aza-BODIPY Dyes

Nagappanpillai Adarsh et al.

ORGANIC LETTERS (2010)

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Pyrrolidylsubstituted Azadipyrromethene with Fully Chelated Boron Atom

Viktor P. Yakubovskyi et al.

SYNTHETIC COMMUNICATIONS (2010)

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Two-Photon Absorption-Related Properties of Functionalized BODIPY Dyes in the Infrared Range up to Telecommunication Wavelengths

Pierre-Antoine Bouit et al.

ADVANCED MATERIALS (2009)

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BIOIMAGING Second window for in vivo imaging

Andrew M. Smith et al.

NATURE NANOTECHNOLOGY (2009)

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B,O-Chelated Azadipyrromethenes as Near-IR Probes

Aurore Loudet et al.

ORGANIC LETTERS (2008)

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Functionalized BF2 chelated azadipyrromethene dyes

Aurore Loudet et al.

TETRAHEDRON (2008)

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Synthesis of N,N-difluoroboryl complexes of 3,3′-diarylazadiisoindolylmethenes

Valentina F. Donyagina et al.

TETRAHEDRON LETTERS (2008)

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BODIPY dyes and their derivatives: Syntheses and spectroscopic properties

Aurore Loudet et al.

CHEMICAL REVIEWS (2007)

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Article Chemistry, Organic

Bis(2-pyridyl)-substituted boratriazaindacene as an NIR-emitting chemosensor for Hg(II)

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Conformationally restricted Aza-BODIPY: Highly fluorescent, stable near-infrared absorbing dyes

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Supramolecular photonic therapeutic agents

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

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In vitro demonstration of the heavy-atom effect for photodynamic therapy

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

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Article Chemistry, Multidisciplinary

Synthesis of BF2 chelates of tetraarylazadipyrromethenes and evidence for their photodynamic therapeutic behaviour

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