☆ 4.7 Article

Drug-induced liver injury and anti-hepatotoxic effect of herbal compounds: a metabolic mechanism perspective

PHYTOMEDICINE (2024)

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CCR2 and CCR5 promote diclofenac-induced hepatotoxicity in mice

Zhanke He et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2019)

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Review Pharmacology & Pharmacy

Statins: Adverse reactions, oxidative stress and metabolic interactions

Aimei Liu et al.

PHARMACOLOGY & THERAPEUTICS (2019)

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Review Plant Sciences

Schisandra fruits for the management of drug-induced liver injury in China: A review

Peili Zhu et al.

PHYTOMEDICINE (2019)

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Green synthesis and biological evaluation of novel 5-fluorouracil derivatives as potent anticancer agents

Farhat Jubeen et al.

SAUDI PHARMACEUTICAL JOURNAL (2019)

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Review Chemistry, Multidisciplinary

Cytochrome P450 1B1: role in health and disease and effect of nutrition on its expression

Bakht Ramin Shah et al.

RSC ADVANCES (2019)

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Article Medicine, General & Internal

Statin-Induced Rhabdomyolysis, Acute Kidney Injury, and Hepatitis Leading to Death

Mouhand F. H. Mohamed et al.

AMERICAN JOURNAL OF CASE REPORTS (2019)

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Article Biochemistry & Molecular Biology

Aqueous leaves extract of Madhuca longifolia attenuate diclofenac-induced hepatotoxicity: Impact on oxidative stress, inflammation, and cytokines

Jerine Peter Simon et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

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Article Nutrition & Dietetics

Dietary Silymarin Supplementation Alleviates Zearalenone-Induced Hepatotoxicity and Reproductive Toxicity in Rats

Xin Gao et al.

JOURNAL OF NUTRITION (2018)

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Article Multidisciplinary Sciences

Silymarin prevents acetaminophen-induced hepatotoxicity in mice

Zuzana Papackova et al.

PLOS ONE (2018)

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Article Toxicology

Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism

Katarzyna E. Lazarska et al.

TOXICOLOGY LETTERS (2018)

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Article Toxicology

Isoniazid-induced hepatotoxicity and neurotoxicity in rats investigated by 1H NMR based metabolomics approach

Ling-Yu Ruan et al.

TOXICOLOGY LETTERS (2018)

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Review Food Science & Technology

Protective effects of plant-derived flavonoids on hepatic injury

Lin Wan et al.

JOURNAL OF FUNCTIONAL FOODS (2018)

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Article Plant Sciences

Sagittaria sagittifolia polysaccharide protects against isoniazid- and rifampicin-induced hepatic injury via activation of nuclear factor E2-related factor 2 signaling in mice

Jing Wang et al.

JOURNAL OF ETHNOPHARMACOLOGY (2018)

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Article Food Science & Technology

Silymarin prevents acetaminophen-induced hepatotoxicity via up-regulation of the glutathione conjugation capacity in mice

Young Chul Kim et al.

JOURNAL OF FUNCTIONAL FOODS (2018)

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Review Food Science & Technology

A critical review on hepatoprotective effects of bioactive food components

Kumar Ganesan et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2018)

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Review Gastroenterology & Hepatology

Liver Injury From Herbal and Dietary Supplements

Victor J. Navarro et al.

HEPATOLOGY (2017)

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Article Biochemistry & Molecular Biology

Mechanism Investigation of Rifampicin-Induced Liver Injury Using Comparative Toxicoproteomics in Mice

Ju-Hyun Kim et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

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Article Pharmacology & Pharmacy

Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin

Leiyan He et al.

XENOBIOTICA (2017)

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Article Medicine, Research & Experimental

L-Methionine and silymarin: A comparison of prophylactic protective capabilities in acetaminophen-induced injuries of the liver, kidney and cerebral cortex

Olakunle J. Onaolapo et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

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Article Biochemistry & Molecular Biology

Modulatory effect of silymarin on nuclear factor-erythroid-2-related factor 2 regulated redox status, nuclear factor-κB mediated inflammation and apoptosis in experimental gastric ulcer

Walaa Arafa Keshk et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2017)

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Article Gastroenterology & Hepatology

Mechanisms of Drug-Induced Hepatotoxicity

Amina Ibrahim Shehu et al.

CLINICS IN LIVER DISEASE (2017)

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Review Pharmacology & Pharmacy

Mechanism of isoniazid-induced hepatotoxicity: then and now

Imir Metushi et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2016)

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Article Chemistry, Medicinal

Chronic Treatment with Isoniazid Causes Protoporphyrin IX Accumulation in Mouse Liver

Madhav Sachar et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2016)

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Editorial Material Anesthesiology

Hepatotoxicity due to red bush tea consumption: a case report

Shamantha Reddy et al.

JOURNAL OF CLINICAL ANESTHESIA (2016)

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Monoammonium glycyrrhizinate protects rifampicin- and isoniazid-induced hepatotoxicity via regulating the expression of transporter Mrp2, Ntcp, and Oatp1a4 in liver

Liting Zhou et al.

PHARMACEUTICAL BIOLOGY (2016)

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Article Public, Environmental & Occupational Health

Prevalence, risk factors, management, and treatment outcomes of first-line antituberculous drug-induced liver injury: a prospective cohort study

Qin Sun et al.

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2016)

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Article Multidisciplinary Sciences

Rifampicin-Induced Hepatic Lipid Accumulation: Association with Up-Regulation of Peroxisome Proliferator-Activated Receptor γ in Mouse Liver

Jia-Hui Huang et al.

PLOS ONE (2016)

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Drug-Induced Liver Toxicity and Prevention by Herbal Antioxidants: An Overview

Divya Singh et al.

FRONTIERS IN PHYSIOLOGY (2016)

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Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro

Yueping Zhang et al.

DRUG METABOLISM AND DISPOSITION (2016)

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Cellular Homeostasis and Repair in the Mammalian Liver

Ben Z. Stanger

ANNUAL REVIEW OF PHYSIOLOGY, VOL 77 (2015)

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Critical review of resveratrol in xenobiotic-induced hepatotoxicity

Mitchell R. McGill et al.

FOOD AND CHEMICAL TOXICOLOGY (2015)

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Article Biochemistry & Molecular Biology

Distribution of mitochondrial DNA fragments in the nuclear genome of the honeybee

W. X. Du et al.

GENETICS AND MOLECULAR RESEARCH (2015)

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Drug-induced liver injury: Interactions between drug properties and host factors

Minjun Chen et al.

JOURNAL OF HEPATOLOGY (2015)

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Chronic liver injury induced by drugs: a systematic review

Jonathan G. Stine et al.

LIVER INTERNATIONAL (2015)

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Review Biochemistry & Molecular Biology

Curcumin, Inflammation, and Chronic Diseases: How Are They Linked?

Yan He et al.

MOLECULES (2015)

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Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1-p53 signaling pathways

Ying Wang et al.

TOXICOLOGY LETTERS (2015)

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Effects of nanoparticle-encapsulated curcumin on arsenic-induced liver toxicity in rats

Palanisamy Sankar et al.

ENVIRONMENTAL TOXICOLOGY (2015)

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Hepatoprotective properties of extensively studied medicinal plant active constituents: Possible common mechanisms

Hassan Farghali et al.

PHARMACEUTICAL BIOLOGY (2015)

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Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application

Romilly E. Hodges et al.

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ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

Naga P. Chalasani et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2014)

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Ameliorative Action of Curcumin in Cisplatin-mediated Hepatotoxicity: An In Vivo Study in Wistar Rats

Mohammad Waseem et al.

ARCHIVES OF MEDICAL RESEARCH (2014)

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Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats

Mohamed Mohamed Soliman et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)

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Protective effect of resveratrol on sodium fluoride-induced oxidative stress, hepatotoxicity and neurotoxicity in rats

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FOOD AND CHEMICAL TOXICOLOGY (2014)

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Protective Effects of Resveratrol on Hepatotoxicity Induced by Isoniazid and Rifampicin via SIRT1 Modulation

Natalia F. Nicoletti et al.

JOURNAL OF NATURAL PRODUCTS (2014)

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Pharmacogenomics of acetaminophen in pediatric populations: a moving target

Anne E. Krasniak et al.

FRONTIERS IN GENETICS (2014)

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Hepatoprotective effect of ethanolic extract of Curcuma longa on thioacetamide induced liver cirrhosis in rats

Suzy M. Salama et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013)

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Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers

Bharat B. Aggarwal et al.

BRITISH JOURNAL OF PHARMACOLOGY (2013)

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Biochemical and molecular mechanisms of N-acetyl cysteine and silymarin-mediated protection against maneb- and paraquat-induced hepatotoxicity in rats

Israr Ahmad et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2013)

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Emerging Transporters of Clinical Importance: An Update From the International Transporter Consortium

K. M. Hillgren et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)

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Nonsteroidal Anti-Inflammatory Drug-Induced Hepatoxicity

Alberto Unzueta et al.

CLINICS IN LIVER DISEASE (2013)

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Resveratrol attenuates hepatotoxicity of rats exposed to arsenic trioxide

Weiqian Zhang et al.

FOOD AND CHEMICAL TOXICOLOGY (2013)

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Receptor Interacting Protein Kinase 3 Is a Critical Early Mediator of Acetaminophen-induced Hepatocyte Necrosis in Mice

Anup Ramachandran et al.

HEPATOLOGY (2013)

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Resveratrol ameliorates methotrexate-induced hepatotoxicity in rats via inhibition of lipid peroxidation

S. Dalaklioglu et al.

HUMAN & EXPERIMENTAL TOXICOLOGY (2013)

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Hepatoprotective effect of Cissus quadrangularis stem extract against rifampicin-induced hepatotoxicity in rats

A. H. M. Viswanatha Swamy et al.

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2013)

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Methanol extract from the stem of Cotinus coggygria Scop., and its major bioactive phytochemical constituent myricetin modulate pyrogallol-induced DNA damage and liver injury

Sanja Matic et al.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2013)

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Hepatic lipid metabolic pathways modified by resveratrol in rats fed an obesogenic diet

Goiuri Alberdi et al.

NUTRITION (2013)

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Ginkgo biloba leaves extract (EGb 761) attenuates lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and NF-κB-dependent matrix metalloproteinase-9 pathway

Chun-Hsiung Huang et al.

PHYTOMEDICINE (2013)

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Curcumin protects against acetaminophen-induced apoptosis in hepatic injury

Gang Li et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2013)

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Traditional West African pharmacopeia, plants and derived compounds for cancer therapy

Wamtinga Richard Sawadogo et al.

BIOCHEMICAL PHARMACOLOGY (2012)

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Differential effects of low-dose resveratrol on adiposity and hepatic steatosis in diet-induced obese mice

Su-Jung Cho et al.

BRITISH JOURNAL OF NUTRITION (2012)

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Discovery of curcumin, a component of golden spice, and its miraculous biological activities

Subash C. Gupta et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2012)

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A Perspective on Efflux Transport Proteins in the Liver

K. Koeck et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)

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Protective effect of curcumin, silymarin and N-acetylcysteine on antitubercular drug-induced hepatotoxicity assessed in an in vitro model

M. Singh et al.

HUMAN & EXPERIMENTAL TOXICOLOGY (2012)

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Prediction of Liver Injury Induced by Chemicals in Human With a Multiparametric Assay on Isolated Mouse Liver Mitochondria

Mathieu Porceddu et al.

TOXICOLOGICAL SCIENCES (2012)

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Silibinin Activated p53 and Induced Autophagic Death in Human Fibrosarcoma HT1080 Cells via Reactive Oxygen Species-p38 and c-Jun N-Terminal Kinase Pathways

Wen-Jun Duan et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)

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Extract of the plant Cotinus coggygria Scop. attenuates pyrogallol-induced hepatic oxidative stress in Wistar rats

Sanja Matic et al.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2011)

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Hepatoprotective effects of polyprenols from Ginkgo biloba L. leaves on CCl4-induced hepatotoxicity in rats

Lan Yang et al.

FITOTERAPIA (2011)

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Hepatotoxicity associated with statins: Reports of idiosyncratic liver injury post-marketing

Einar Björnsson et al.

JOURNAL OF HEPATOLOGY (2011)

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Heat stress-induced hepatotoxicity and its prevention by resveratrol in rats

Asima Das

TOXICOLOGY MECHANISMS AND METHODS (2011)

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Pyrogallol-mediated toxicity and natural antioxidants: Triumphs and pitfalls of preclinical findings and their translational limitations

Ghanshyam Upadhyay et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2010)

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Involvement of multiple molecular events in pyrogallol-induced hepatotoxicity and silymarin-mediated protection: Evidence from gene expression profiles

Ghanshyam Upadhyay et al.

FOOD AND CHEMICAL TOXICOLOGY (2010)

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Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice

Joshua D. Lambert et al.

FOOD AND CHEMICAL TOXICOLOGY (2010)

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c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity

Chieko Saito et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2010)

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Nrf2:INrf2 (Keap1) signaling in oxidative stress

James W. Kaspar et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

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Nonprescription Use of Pain Relievers by Middle-Aged and Elderly Community-Living Adults: National Survey on Drug Use and Health

Dan G. Blazer et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2009)

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Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats

Jiang Yue et al.

PHARMACOLOGICAL RESEARCH (2009)

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Resveratrol modulates pyrogallol-induced changes in hepatic toxicity markers, xenobiotic metabolizing enzymes and oxidative stress

Ghanshyam Upadhyay et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2008)

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CYP2E1 and oxidative liver injury by alcohol

Yongke Lu et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

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Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury

Michael P. Holt et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2008)

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Curcumin, demethtoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism

Santosh K. Sandur et al.

CARCINOGENESIS (2007)

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Article Pharmacology & Pharmacy

Effect of silymarin on pyrogallol- and rifampicin-induced hepatotoxicity in mouse

Ghanshyam Upadhyay et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2007)

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Lymphocyte loss and immunosuppression following acetaminophen-induced hepatotoxicity in mice as a potential mechanism of tolerance

Mary Jane Masson et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2007)

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Isoniazid-induced hepatotoxicity in rat hepatocytes of gel entrapment culture

Chong Shen et al.

TOXICOLOGY LETTERS (2006)

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Bioactivation and hepatotoxicity of nitroaromatic drugs

Urs A. Boelsterli et al.

CURRENT DRUG METABOLISM (2006)

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Protective effects of resveratrol against acetaminophen-induced toxicity in mice

Goksel Sener et al.

HEPATOLOGY RESEARCH (2006)

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Protective effects of Ginkgo biloba against acetaminophen-induced toxicity in mice

G Sener et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2006)

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Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity

Yuichi Yamazaki et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2005)

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Hepatoprotective effect of new livfit®, a polyherbal formulation, is mediated through its free radical scavenging activity

YK Gupta et al.

PHYTOTHERAPY RESEARCH (2004)

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