4.3 Article

Diabetic Soft Tissue Infections

Journal

SURGICAL CLINICS OF NORTH AMERICA
Volume 103, Issue 6, Pages 1191-1216

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.suc.2023.06.002

Keywords

Diabetic foot; Infection; Diabetes; Necrotizing soft tissue infection; Soft tissue infections; Cellulitis

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Diabetes can have various physiological effects, including increased infection rates, impaired wound healing, and higher risk for complex soft tissue infections. Clinicians and surgeons should be highly suspicious of severe infection in patients with diabetes, especially those with uncontrolled diabetes.
Diabetes is a systemic illness that can cause a broad range of physiologic effects. Infection rates and wound healing are both affected through multiple mechanisms. Other physiologic changes increase risk for wounds as well as complex soft tissue infections ranging from simple cellulitis to necrotizing soft tissue infections. Clinicians and surgeons need to have a low index of suspicion for severe infection in a patient presenting with diabetes, and even more so in patients with uncontrolled diabetes.

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