4.7 Review

Time-Restricted Eating and Its Metabolic Benefits

Journal

JOURNAL OF CLINICAL MEDICINE
Volume 12, Issue 22, Pages -

Publisher

MDPI
DOI: 10.3390/jcm12227007

Keywords

circadian rhythm; fasting; lifestyle; time restricted; weight loss

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New research suggests that time-restricted eating (TRE) has positive effects on weight loss and various diseases, such as nonalcoholic fatty liver disease, cancer, and cardiovascular disease. It is found to be equivalent to calorie restriction for weight loss.
Newer management strategies are being evaluated to treat obesity, which continues to increase worldwide. After 12 h of fasting, the body switches from glucose to fat metabolism, regulating protein synthesis and autophagy. These cellular responses are central to the metabolic benefits of time-restricted eating (TRE), independent of calorie restriction and weight loss, and they have heightened interest in TRE regimens. Controversy remains, however, regarding the benefits of TRE regimens. We reviewed the current literature and concluded that TRE is equivalent to calorie restriction for weight loss and has positive effects for patients with diseases such as nonalcoholic fatty liver disease, cancer, and cardiovascular disease.

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