Related references
Note: Only part of the references are listed.
Article
Chemistry, Multidisciplinary
Rui Liu et al.
Summary: Decades have passed since the approval of the first nanoparticles-based medicine for human cancer treatment, and research and development in nanoparticles for drug delivery have been continuing. Today, there have been significant advancements in nanoparticles, including liposomes, solid lipid nanoparticles, inorganic nanoparticles, micelles, nanovaccines, and nano-antibodies. These nanoparticles have shown great potential in the treatment and diagnosis of challenging diseases such as cancer and neurodegenerative diseases, making them promising drug carriers and therapeutic agents in the future.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Benjamin Barclay et al.
Summary: 3D printed nanocomposites have the potential to create high-performance radio frequency devices. However, little is known about how the diameter of the nanoparticles used in these composites affect their performance. This study develops a range of 3D printable nanocomposite inks with nanoparticles ranging from 30 to 300 nm in diameter. The relative permittivity of the printed nanocomposites is unaffected by nanoparticle diameter, but the loss tangent, glass transition temperature, and elastic modulus are altered. This research provides a framework for designing 3D printable nanocomposites and emphasizes the importance of nanoparticle diameter in formulation strategy.
Article
Multidisciplinary Sciences
Natalie M. Larson et al.
Summary: This article presents a rotational multimaterial 3D printing (RM-3DP) platform that allows subvoxel control over the local orientation of azimuthally heterogeneous architected filaments. By continuously rotating a multimaterial nozzle with a controlled ratio of angular-to-translational velocity, helical filaments with programmable helix angle, layer thickness, and interfacial area between different materials can be created. Functional artificial muscles and hierarchical lattices composed of architected helical struts have been successfully fabricated using this method.
Review
Chemistry, Physical
Dhriti Nepal et al.
Summary: This Review discusses recent advancements in bioinspired nanocomposite design, focusing on the role of hierarchical structuring at different length scales in creating multifunctional, lightweight, and robust structural materials. By manipulating the architecture, interphases, and confinement, dynamic and synergistic responses have been achieved. The study highlights the significance of hierarchical structures across multiple length scales for achieving multifunctionality and robustness.
Article
Biochemical Research Methods
Helena Gavilan et al.
Summary: This article presents a solvothermal-based method for preparing gram-scale ferrite nanoparticles with well-defined shapes (such as nanocubes and nanostars) and fine control of structural and magnetic properties. The shape of the nanoparticles can be controlled by adjusting the aldehyde ligand used. Cubic ferrite nanoparticles can be obtained using benzaldehyde and its derivatives, while aliphatic aldehydes result in spherical nanoparticles. By replacing the primary amine with a secondary or tertiary amine, star-like nanoparticles can be obtained. The precise control over shape, size distribution, composition, and crystallinity ensures the preparation of gram-scale nanocubes/star-like nanoparticles with specific adsorption rates comparable to or better than those prepared by thermal decomposition methods. This method can be completed in approximately 10 hours with an average level of expertise in chemistry.
Article
Chemistry, Multidisciplinary
Alexander Groetsch et al.
Summary: This study demonstrates the fabrication of non-cytotoxic nanocomposite ink using cellulose nanocrystals (CNCs) as reinforcement for printing and tuning complex 3D structures. It shows that the addition of CNCs significantly increases the stiffness of the composites. The insights gained from this study have implications for applications in medical, electronic, and energy fields.
Article
Chemistry, Multidisciplinary
Mohsen Esmaeili et al.
Summary: Inspired by natural Bouligand structures, researchers have successfully used cellulose nanocrystals (CNC)-based inks for 3D printing to create structures with guided long-range radial twisted chirality. The nanostructures during the printing process were evaluated using rheological measurements, in situ flow analysis, polarized optical microscopy (POM), and director field analysis. By incorporating a photo-curable monomer, the chirality of the printed filaments was locked, and optimized Carbopol microgels were used to support the as-printed inks before photo-polymerization. This biomimetic approach opens up new possibilities for developing bio-inspired materials with nanoscale hierarchies in larger-scale 3D printed constructs.
Article
Chemistry, Multidisciplinary
Qianyi Zhang et al.
Summary: The researchers propose a facile and generalizable film-coating method using zeolitic imidazole framework-8 (ZIF-8) to immobilize antibodies on various nanoparticles for enhanced cell targeting. This method allows efficient assembly of different model and therapeutic antibodies on nanoparticles via biomineralized film-coating, resulting in high antibody loading and targeting efficiencies. The antibodies selectively bind to ZIF-8 via their Fc regions, exposing the functional Fab regions to the biological target and improving the cell targeting ability of antibody-coated nanoparticles.
Review
Engineering, Biomedical
Bin Kong et al.
Summary: Nano/micro fibers have attracted much attention in fiber science due to their special functions and properties, and they have a wide range of applications in fields such as environmental engineering, electronics, and biomedicine.
BIOACTIVE MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Shahzad Hafeez et al.
Summary: Traditional synthetic covalent hydrogels lack the native tissue dynamics and hierarchical fibrous structure found in the extracellular matrix (ECM). Here, the molecular tuning of a supramolecular benzene-1,3,5-tricarboxamide (BTA) hydrogelator via simple modulation of hydrophobic substituents is reported. These hydrogels show high cell viability for chondrocytes and human mesenchymal stem cells, establishing their use in tissue engineering applications.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Tamara Munoz-Ortiz et al.
Summary: Nanothermometry utilizes nanoparticles as thermal probes, enabling remote and minimally invasive sensing. It has emerged as a powerful tool in biomedicine. However, the lack of 3D thermal imaging capability and readily available tools in clinic hinders its translation to the bedside.
ADVANCED MATERIALS
(2023)
Article
Engineering, Biomedical
Ting Li et al.
Summary: This study aims to develop an interpenetrating network (IPN) hydrogel with tunable stress relaxation using a combination of gelatin methacryloyl (GelMA) and fibrinogen. These IPN hydrogels with faster stress relaxation showed higher 3D cellular proliferation and better differentiation. The cellfree 3D printed scaffold was implanted into a rat VML model, and both the short and long-term repair results demonstrated its ability to enhance functional skeletal muscle tissue regeneration.
ACTA BIOMATERIALIA
(2023)
Review
Engineering, Environmental
Muhammad Muzammal Hussain et al.
Summary: Carbon dots (CDs) with near-infrared (NIR) emission are promising nanomaterials for biomedical applications due to their low toxicity, superior photostability, and targeting ability. While yellow and green CDs offer excellent photostability, water solubility, and biocompatibility, red/near-infrared CDs provide additional benefits such as minimal autofluorescence, reduced photodamage, and deep tissue penetration. This review highlights the recent progress in the development of strategies for red/near-infrared CDs and their potential biomedical applications, as well as the influence of physicochemical parameters on their formation mechanism. Categorization of multicolor CDs based on size or other factors is also discussed.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Biochemistry & Molecular Biology
Davood Kharaghani et al.
Summary: In recent years, promising scaffolds for advanced tissue engineering have been developed using nanofibers and 3D printing technologies. However, maintaining structural integrity and promoting cell proliferation remain challenges for scaffold design. Nanofiber-reinforced hydrogels have shown improved mechanical properties and cell growth, making them biomimetic scaffolds with potential for biomedical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Noor Al-Jawuschi et al.
Summary: In this study, a 3D aerogel-based composite scaffold with a dual-network structure was successfully fabricated for successive tumor therapy and tissue regeneration. The scaffold exhibited photothermal triggered controlled drug release and cancer cell ablation. Additionally, the scaffold showed excellent biodegradation properties, making it a potential implant for tissue regeneration.
Article
Chemistry, Multidisciplinary
Sumin Jeong et al.
Summary: This study presents a hydrogel magneto-mechanical actuator (h-MMA) nanoparticle as a new nanotechnology tool for wireless, target-specific, and long-distance stimulation of mechanoreceptors in vivo. The h-MMA integrates a two-step transduction mechanism to convert magnetic anisotropic energy to thermal energy and then to mechanical energy for inducing contraction of the surrounding polymer shell and activating targeted mechano-receptors. The h-MMAs enable on-demand modulation of Notch signaling in both fluorescence reporter cell lines and a xenograft mouse model, demonstrating its utility as a powerful in vivo perturbation approach for mechano-biology interrogation in a minimally invasive and untethered manner.
Article
Multidisciplinary Sciences
Tingting Song et al.
Summary: This study demonstrates a series of titanium-oxygen-iron compositions with outstanding tensile properties, achieved through alloy design and additive manufacturing. These alloys, strengthened by the abundant elements of oxygen and iron, offer potential for diverse applications and the industrial-scale use of waste sponge titanium. Additionally, they have significant economic and environmental potential for reducing the carbon footprint of energy-intensive sponge titanium production.
Article
Chemistry, Physical
Tao Zhou et al.
Summary: Researchers have developed a bi-continuous conducting polymer hydrogel with high electrical conductivity, stretchability, and toughness for 3D printing soft bioelectronic devices. This hydrogel shows promise for long-term in vivo electrophysiological monitoring and stimulation due to its unique combination of electrical conductivity and tissue-like mechanical properties. The hydrogel achieves high electrical conductivity, stretchability, and fracture toughness in physiological environments, making it suitable for advanced fabrication methods such as 3D printing. The researchers also demonstrate the use of this hydrogel for 3D printing monolithic all-hydrogel bioelectronic interfaces for long-term electrophysiological recording and stimulation in rat models.
Article
Nanoscience & Nanotechnology
Junfang Zhang et al.
Summary: Counterfeiting not only causes trillion-dollar economic losses annually, but also threatens human health, social equity, and national security. Researchers have developed a nanoprinting-assisted flash synthesis approach to create fluorescent nanofilms with physical unclonable function micropatterns in milliseconds. These unclonable patterns can be quickly and independently read out by fluorescence and topography scanning, greatly enhancing their security.
NATURE NANOTECHNOLOGY
(2023)
Article
Engineering, Biomedical
Xiaoxu Yang et al.
Summary: In this study, hydrophilic, biocompatible, and mechanically stable KNF-PVA aerogel gauzes were fabricated using 3D printing technology. These gauzes demonstrated remarkable water permeability and absorption capacity, and the ability to enrich micron-sized particles, resulting in enhanced hemostasis.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Multidisciplinary Sciences
Anna Urciuolo et al.
Summary: This study develops a hydrogel-in-hydrogel bioprinting approach to dynamically control the growth landscape of three-dimensional cell cultures. The technique enables modulation of hydrogel characteristics to guide neural axon directionality, control cell migration in cancer organoids, and promote cell polarity in liver and small intestinal organoids, as well as control lung tip bifurcation.
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Sebastien J. P. Callens et al.
Summary: The organization of bone cells in landscapes with varying curvatures was studied, revealing a preference for local concavities, multicellular bridging, and collective stress fiber orientation.
NATURE COMMUNICATIONS
(2023)
Review
Engineering, Biomedical
Huifeng Shao et al.
Summary: Bacterial infection caused by biomaterials is a serious problem in implant clinical treatment. The emergence of antibiotic resistance has led to the exploration of alternative antibacterial agents, with silver being a promising candidate due to its high antibacterial properties and low susceptibility to resistance. However, the cytotoxicity of silver poses challenges for its application in biomaterials.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Nectarios Vidakis et al.
Summary: Acrylonitrile Butadiene Styrene (ABS) nanocomposites with Titanium Nitride (TiN) nanoparticles were developed using Material Extrusion (MEX) Additive Manufacturing (AM) and Fused Filament Fabrication (FFF) methods. Mechanical tests and morphological characterization were conducted to investigate the effect of TiN nanoparticles on the mechanical performance and surface characteristics of the nanocomposites. The inclusion of 6 wt. % of TiN nanoparticles significantly improved the mechanical properties of the ABS/TiN composites, including flexural modulus of elasticity and toughness.
Article
Chemistry, Multidisciplinary
Yongcong Fang et al.
Summary: In this study, a conductive multiscale filled NGC (MF-NGC) is developed, which significantly enhances peripheral nerve regeneration. The printed MF-NGCs possess good permeability, mechanical stability, and electrical conductivity, promoting the elongation and growth of Schwann cells and neurite outgrowth. Animal studies demonstrate that the MF-NGCs promote neovascularization and M2 transition, leading to improved peripheral nerve regeneration. This study demonstrates the feasibility of using 3D-printed conductive MF-NGCs with hierarchically oriented fibers as functional conduits.
Article
Chemistry, Multidisciplinary
Adam C. Farsheed et al.
Summary: 3D printing is extensively utilized in biomedical research, particularly for creating structures that mimic the mechanical properties of biological tissues. However, there is a challenge in 3D printing hydrogels due to the difficulty in patterning soft materials in three dimensions. To address this, novel hydrogels with desirable biological properties are needed as 3D printable inks.
ADVANCED MATERIALS
(2023)
Article
Biophysics
Xue Deng et al.
Summary: Micro/nanorobots can convert various energy sources into power effectively, providing highly efficient resources for human beings at the micro/nanoscale. Magnetic micro/nanorobots have gained significant attention in biological detection and targeted delivery due to their unique motion characteristics, non-damaging penetration through biological tissues, and wireless remote control manipulability. Progress in the design, manufacturing, and operation of magnetic micro/nanorobots has greatly enhanced their functional integrity and applicability in biomedicine, showing their immense potential. This review summarizes the latest applications and future development prospects of magnetic micro/nanorobots in biological detection and targeted delivery, introducing the concepts of connotation, driving modes, and functional strategies. Finally, the potential advantages and future research directions of magnetic micro/nanorobots are discussed, providing clear evidence of the significant impact the integration of robots, detection, medicine, and other technologies will have on future biomedical applications.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Cell & Tissue Engineering
SeoYul Jo et al.
Summary: This study proposes a versatile handheld 3D printer for the fabrication of porous cell-laden methacrylated gelatin (GelMa) with high porosity. The printer utilizes air injection and a bubble-making system using mesh filters to pass a mixture of air/GelMa bioink. The cell constructs' pore size and foamability can be manipulated by adjusting various processing parameters. In vitro and in vivo tests demonstrate the viability and efficacy of the printed cell constructs for muscle regeneration.
NPJ REGENERATIVE MEDICINE
(2023)
Article
Engineering, Environmental
Tianrui Cui et al.
Summary: With the increasing concern for cardiovascular health, a multifunctional electronic skin (e-skin) based on MXene-Polyurethane mesh (MPM) has been developed for long-term electrocardiographic (ECG) monitoring. The MPM e-skin shows low electrode-skin contact impedance, high signal-to-noise ratio, and high breathability, and can be continuously worn for at least 7 days. By combining the MPM e-skin with a flexible printed circuit board (FPCB) and an intelligent algorithm, the acquired wearable intelligent e-skin system can accurately monitor and diagnose arrhythmias.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Biomedical
Zhuoyuan Li et al.
Summary: In this study, a composite photocrosslinked silk fibroin/gelatin hydrogel loaded with methylene blue/UiO-66(Ce) nanoparticles was fabricated. The hydrogel exhibited good biocompatibility, promoted cell migration and proliferation, and showed excellent antibacterial effect. It also accelerated the repair rate of full-thickness skin defects in mice.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Chemistry, Physical
Suji Choi et al.
Summary: A hydrogel ink containing prefabricated gelatin fibers was developed to print organ-level scaffolds that mimic the organization of the heart. The addition of gelatin fibers allowed for controlled printing of free-standing 3D structures without additional support. The aligned fibers promoted the self-organization of human cardiomyocytes into anisotropic muscular tissues.
Article
Chemistry, Multidisciplinary
Hayoung Jun et al.
Summary: A strategy of converting atRA into injectable antithrombotic nanoparticles using a boronate linker has been developed, demonstrating high therapeutic efficacy in inhibiting thrombus formation.
Review
Pharmacology & Pharmacy
Karen Al-Litani et al.
Summary: Modern pharmaceutical interventions are moving towards personalized therapies using three-dimensional printing technology. While 3DP has been successfully applied in manufacturing drugs, research on implantable drug delivery devices lags behind other areas. Efforts to address gender inequality in healthcare should drive more research, particularly utilizing emerging technologies like 3DP. This review focuses on the unique opportunity of using 3DP for personalized implantable drug delivery systems for women's health applications, highlighting current challenges and regulatory status.
ADVANCED DRUG DELIVERY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Joshua Tropp et al.
Summary: This study reports a new type of hydrogel material with high conductivity and dispersibility, which can transmit signals between living tissue and medical devices. The material can be used to manufacture flexible organic bioelectronic materials with a wide range of potential applications.
ADVANCED MATERIALS
(2023)
Article
Engineering, Biomedical
Xiaobin Chen et al.
Summary: Proposed a novel injectable magnetic and ferroptotic hydrogel to overcome the obstacles in the clinical application of magnetic hyperthermia therapy (MHT) and enhance its antitumor efficacy.
Article
Multidisciplinary Sciences
Bingyan Liu et al.
Summary: The researchers demonstrate a fast 3D nanoprinting technique for manufacturing nanostructured arrays of multiple materials and geometries over millimeter-scale areas by manipulating electric and flow fields. This technique has exciting prospects in the fields of nanophotonics and nanoelectronics.
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Chen Xin et al.
Summary: The authors developed micrometer scale soft robots with multiple microjoints that can achieve different deformation modes, utilizing a two-in-one femtosecond laser strategy to create microactuators composed of hydrogel and metal nanoparticles. These microactuators have short response times and require low actuation power. The ability to integrate multiple microjoints into soft robots at the micrometer scale represents a significant challenge.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Britta Weidinger et al.
Summary: A new approach utilizing self-assembled printable materials based on block copolymers is presented, enabling precise control of nanostructure in 3D. This work achieves controlled nano-order within the entire 3D structures, allowing for the fabrication of complex 3D microstructures with tailor-made nanostructures.
Article
Infectious Diseases
Giulia Remaggi et al.
Summary: Two antimicrobial agents, silver nanoparticles and titanium dioxide, have been formulated with natural polysaccharides to develop innovative inks for 3D-printed dressings. These dressings exhibit suitable chemical-physical properties, antimicrobial activities against Gram+ and Gram- bacteria, and biocompatibility. The dressings are cheap, highly defined, and easy to manufacture, making them ideal for personalized antimicrobial medicine applications.
Article
Cell & Tissue Engineering
Yongfeng Li et al.
Summary: This study aimed to fabricate 3D-printing titanium grid scaffolds to achieve bone fusion in mandibular segmental defects. The results showed that the scaffolds with sufficient pores and basic biomechanical strength could facilitate bone regeneration and integration of bone broken ends. Clinical observations on both animal models and patients confirmed the successful bone regeneration in mandibular defects using the titanium grid scaffolds.
NPJ REGENERATIVE MEDICINE
(2023)
Review
Engineering, Electrical & Electronic
Faheem Ershad et al.
Summary: In recent years, there has been a rapid expansion of wearable bioelectronics for diagnosing, monitoring, and treating various pathological conditions from the skin surface. This perspective summarizes the state-of-the-art in situ fabricated wearable bioelectronics, focusing on the Drawn-on-Skin (DoS) bioelectronics and other in situ fabrication methods. The advantages and limitations of these technologies are evaluated, and potential future directions are suggested for their widespread adoption in everyday life.
NPJ FLEXIBLE ELECTRONICS
(2023)
Article
Multidisciplinary Sciences
Riccardo Levato et al.
Summary: Light-based vat-polymerization bioprinting allows computer-aided patterning of 3D cell-laden structures using photoactivatable bioresin in vats. This technology, divided into stereolithography, digital light processing and volumetric additive manufacturing, has been widely developed and applied in biomedicine. This Primer introduces the methodology and variations of light-based vat-polymerization 3D bioprinting, as well as discusses key assessments and future directions of this method.
NATURE REVIEWS METHODS PRIMERS
(2023)
Article
Chemistry, Multidisciplinary
Yong Wang et al.
Summary: This study introduces a novel approach using MNRs as maneuverable immunoassay probes to achieve automated and efficient ELISA analysis, significantly reducing assay time and minimizing manpower input.
Review
Chemistry, Multidisciplinary
Yue Wang et al.
Summary: The rapid development of 3D printing has had a significant impact on the field of biomedical engineering, particularly 4D printing. While there has been progress made in the development of 4D printing for tissue scaffolds and medical devices, there are limitations in printable smart materials and achievable responses with current stimulation sources. This review highlights recent progress in 4D printing, focusing on printing mechanisms, smart ink mechanisms, structural design, and printing technologies. It also summarizes recent studies on tissue/organ regeneration and medical device applications, and discusses current challenges and future perspectives of 4D printing.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Giovanni Bovone et al.
Summary: Moldable hydrogels are versatile materials used in biomedical and industrial applications. This study introduces a simple strategy to reinforce polymer-nanoparticle (PNP) hydrogels by adding alpha-cyclodextrin (alpha CD), resulting in enhanced mechanical properties. The supramolecular reinforcement of CD-PNP hydrogels allows for modular exchange of structural components and enables a wide range of applications.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Jia Heng Teoh et al.
Summary: This study investigates the application of 3D printing to fabricate hydrogel wound dressings with customizable architectures and drug dosages. Results show that 3D printing has the ability to customize drug dosages and drug release rates through co-loading different drugs at various positions and varying the thickness of drug-free layers over drug-loaded layers in the wound dressing.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Robotics
Erina Baynojir Joyee et al.
Summary: This study presents a 3D-printed soft robot with varied material compositions and hierarchical surface structures. The robot exhibits superior locomotion capabilities and versatile functionalities, making it suitable for tasks in harsh environments.
Article
Biochemistry & Molecular Biology
Zhengchao Yuan et al.
Summary: The engineered tracheal scaffolds fabricated using 3D printing and short nanofibers demonstrate similar microstructure and mechanical properties compared to the native trachea, with good biocompatibility and promotion of chondrocytes growth in vitro. After implantation in mice, the scaffolds maintain structural integrity, support neo-vessel formation, and gradually form cartilage-like tissues, showing promise for tracheal regeneration.
MACROMOLECULAR BIOSCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Dibakar Mondal et al.
Summary: The combination of plant-derived polymer resins and mineral-based nanoparticles can create high-performance 3D printable nanocomposites, improving the sustainability of rapid prototyping and additive manufacturing. By substituting and partially substituting certain components, the mechanical properties of the materials can be greatly enhanced.
FRONTIERS IN MATERIALS
(2022)
Review
Chemistry, Multidisciplinary
Federico Montanarella et al.
Summary: Nanocrystals, as a distinct class of nanomaterials, are being increasingly deployed in various devices in modern society and are projected to play a crucial role in the future. However, it is important to recognize that this cutting-edge technology is rooted in millennia of empirical knowledge and craftsmanship.
Article
Chemistry, Multidisciplinary
Xinhua Qu et al.
Summary: This study proposes a novel antimicrobial system to address the challenges of refractory Staphylococcus aureus-related implant infection. The system provides a continuous, prolonged antibacterial effect at the site of infection and significantly reduces immunosuppression, thereby restoring the antimicrobial immune response.
ADVANCED MATERIALS
(2022)
Review
Pharmacology & Pharmacy
Yihua Xu et al.
Summary: This review discusses the application of micro/nanorobots in pharmaceutical field, focusing on targeted drug delivery. Different actuation energy sources and triggered release systems are explored to achieve precise delivery of therapeutics. This review may provide a different perspective or referable guidance for the future development of more flexible targeted delivery systems.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Materials Science, Multidisciplinary
Zhichao Wang et al.
Summary: In this study, a combination of 3D printing and sacrificial template method was explored to fabricate aerogel scaffolds with adjustable macro/micro-pore structure for tissue engineering. The results showed that the aerogel scaffolds possessed suitable mechanical strength and excellent biological properties, making them a promising candidate for tissue engineering applications.
MATERIALS & DESIGN
(2022)
Article
Multidisciplinary Sciences
Samuel N. Sanders et al.
Summary: This study presents a method of volumetric printing using triplet fusion upconversion at low power excitation, overcoming the limitations of nanoscale applications. The introduction of an excitonic strategy allows for the control of the upconversion threshold, supporting different printing schemes.
Article
Materials Science, Composites
Sergey Gaidar et al.
Summary: The study aimed to develop a biodegradable composite material for extrusion applications in 3D printing technology to address the current performance issues with composite materials. Results showed that the composite PLA: PHB + 10% CFs performed the best in terms of thermal properties, with the highest glass transition temperature.
POLYMER COMPOSITES
(2022)
Article
Polymer Science
Ana Iglesias-Mejuto et al.
Summary: In this study, reinforced alginate-hydroxyapatite (HA) aerogel scaffolds were successfully fabricated for bone tissue engineering (BTE) applications by combining extrusion-based 3D-printing and supercritical CO2 gel drying. Intermediate and post-processing strategies such as gel ageing in CaCl2 solutions and glutaraldehyde (GA) chemical crosslinking were utilized to achieve highly crosslinked aerogel scaffolds. The resulting aerogels were dual porous, bio- and hemocompatible, and had high bioactivity dependent on the HA content, marking a significant advance towards optimizing advanced biomaterials and their sterilization.
Review
Engineering, Biomedical
Yanli Cai et al.
Summary: This review paper focuses on the recent developments in cell-laden nanocomposite bioinks for 3D bioprinting and their effects on the properties and performance of the bioinks. The reinforcement mechanisms and interactions between cells and nano-materials are discussed, with an emphasis on bone and cartilage tissue engineering applications. The limitations and future prospects of current cell-laden nanocomposite bioinks are also addressed.
ACTA BIOMATERIALIA
(2022)
Article
Chemistry, Multidisciplinary
Xu Xue et al.
Summary: A CuS-PEG-PCL scaffold with excellent photothermal properties and stable elasticity was designed for efficient bone regeneration. The scaffold released dexamethasone sodium phosphate (Dexp) and promoted osteogenic differentiation of bone cells through controlled release and mild heating.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Review
Engineering, Biomedical
Intan Najwa Humaira Mohamed Haneef et al.
Summary: This article provides a comprehensive review on the mechanical, thermal, and functional properties of polymer nanocomposites with HNT as a reinforcing agent, and also highlights the recent applications of polymer/HNT nanocomposites in the biomedical fields.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2022)
Article
Multidisciplinary Sciences
Jie Ren et al.
Summary: Through laser powder bed fusion, we have successfully printed dual-phase nanolamellar high-entropy alloys with high yield strength and large uniform elongation. The high yield strength is attributed to the dual-phase structure consisting of alternating face-centred cubic and body-centred cubic nanolamellae, while the large tensile ductility arises from the high work-hardening capability of the dual-phase nanolamellae embedded in microscale eutectic colonies.
Editorial Material
Engineering, Electrical & Electronic
Shaoxing Qu
Summary: This embedded 3D printing technique utilizes an alginate-polyacrylamide hydrogel supporting matrix and a conductive silver-hydrogel ink to fabricate hydrogel electronic devices with various embedded circuits, showcasing high flexibility and customization capabilities.
NATURE ELECTRONICS
(2022)
Article
Multidisciplinary Sciences
Huibin Chang et al.
Summary: This study demonstrates the successful fabrication of helical alignments within the heart's musculature, which leads to improvements in cardiac pumping efficiency.
Article
Engineering, Biomedical
Salwa Alshehri et al.
Summary: Three-dimensional bioprinting is a promising method for tissue and organ engineering. However, the development of bioink materials and the diffusion barrier in scaffold materials limit its widespread use. In this study, genetically encoded gas vesicles derived from haloarchaea were used to promote oxygen diffusion in printed constructs. The results showed that cells printed with gas vesicles had increased activity and proliferation, suggesting that gas vesicles can overcome the diffusion barrier and increase oxygen availability in bioprinted constructs. The biodegradable nature of gas vesicle proteins makes them a potential oxygen-promoting material in biological samples.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2022)
Article
Chemistry, Multidisciplinary
Silvia Cometta et al.
Summary: The study demonstrates that immobilizing melimine on mPCL scaffolds can effectively prevent bacterial infections on implant surfaces and inhibit biofilm formation.
Article
Chemistry, Multidisciplinary
Laura Zanetti-Polzi et al.
Summary: Through theoretical investigation, we have revealed the impact of peptide-ligand environment on the pH-responsive fluorescence of gold nanoclusters. Our findings show that subtle changes in the hexapeptide sequence can significantly alter the pH response of the clusters, providing insights into the underlying mechanism.
Article
Multidisciplinary Sciences
Max A. Saccone et al.
Summary: Metal additive manufacturing enables the production of high value and high performance components through layer-by-layer fabrication. A new technique called vat photopolymerization (VP) is introduced, which allows the production of metals and alloys with microscale resolution. This technique does not require reoptimization of resins and curing parameters for different materials, enabling quick fabrication and compositional tuning.
Article
Multidisciplinary Sciences
Cheng Zeng et al.
Summary: In this study, capillary forces are dynamically modulated to move objects in programmable two-dimensional patterns. Machines are designed to translate, rotate, separate, and braid multiple floating objects. This approach provides a quick, inexpensive way to manipulate micrometre-scale particles and braid microwires for high-frequency electronics.
Article
Chemistry, Physical
Yuman Zhu et al.
Summary: Laser additive manufacturing can be used to create unique internally twinned nanoprecipitates in commercial titanium alloys, leading to the fabrication of ultrastrong metallic materials with complex shapes for various applications. By exploiting thermal cycling and rapid solidification, additive manufacturing can produce titanium alloys that are both ultrastrong and thermally stable, making them suitable for direct implementation. After simple post-heat treatment, a commercial titanium alloy demonstrated adequate elongation and tensile strengths over 1,600 MPa. These excellent properties are attributed to the formation of dense, stable, and internally twinned nanoprecipitates, which are rarely observed in traditionally processed titanium alloys. This work opens up possibilities for fabricating structural materials with unique microstructures and excellent properties.
Article
Chemistry, Multidisciplinary
Tian Li et al.
Summary: This research proposes a conceptual combination of bioinspired microstructure design and a programmable prestrain approach for 4D printing of nanoceramics. By replicating the bioinspired concentric cylinder structure and applying prestrain, the researchers successfully developed flexible nanoceramic composites with superior mechanical performance and anisotropic thermal management capability. Conductive nanoceramic composites with unique sensing capability were also prepared. This breakthrough in 4D printing of ceramics opens up possibilities for high-performance shape morphing materials in extreme conditions.
Article
Multidisciplinary Sciences
Wing Chung Liu et al.
Summary: The authors developed a magnetically assisted drop-on-demand 3D printing technique (MDOD) to print aligned microplatelet reinforced composites. By performing drop-on-demand printing using aqueous slurry inks while applying an external magnetic field, MDOD can achieve the printing of aligned microplatelet fillers with high filler concentrations up to 50 vol%. Moreover, MDOD allows multimaterial printing with voxelated control, and it can be used to manufacture sensors with tunable performances based on local microstructure and composition.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Weizhi Zou et al.
Summary: Vat-photopolymerization-based 3D printing is combined with the sol-gel process to produce advanced functional materials with complex shapes and hierarchical pore structures. Programmable post-printing processes enable the production of high-performance and multifunctional interpenetrating phase nanocomposites. This study provides new guidelines for the design and fabrication of novel materials by additive manufacturing.
Review
Engineering, Biomedical
Jessica Mancilla-De-la-Cruz et al.
Summary: This paper presents the use of 3D printing technology in drug delivery applications. The different variations of the technique according to characteristics, materials, and dosage forms are discussed. The seven main categories of 3D printing and the most frequent materials used are introduced. The paper also explores different forms of drug dosage and provides insights for those interested in the advancement of drug delivery and the development of 3D printing applications in this area.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2022)
Article
Chemistry, Multidisciplinary
Xuan Li et al.
Summary: This study proposes a vibration-assisted nanoneedle/microfluidic composite system for rapid puncturing and detachment of suspension cells, achieving continuous high-throughput intracellular delivery. The system can deliver Cas9 ribonucleoprotein complexes directly into cells, with a delivery efficiency of up to 98% for difficult-to-transfect immune cells.
Review
Nanoscience & Nanotechnology
Chen Qin et al.
Summary: The application of inorganic biomaterials in regenerative medicine is expanding, and functional bioinks based on inorganic biomaterials have been developed for 3D bioprinting of inorganic/organic/cell-laden systems for tissue regeneration. This review summarizes the existing inorganic biomaterials-based bioinks (referred to as inorganic-bioinks) and highlights their improved printability, mechanical strength, and bioactivity for tissue regeneration. The current applications of inorganic-bioinks in constructing 3D cell-laden scaffolds for tissue regeneration are presented, along with the challenges and prospects for inorganic biomaterials-based bioprinting strategy.
Review
Nanoscience & Nanotechnology
Weijie Wu et al.
Summary: This review summarizes recent advances in functional nanomaterial-based suspension array technology, analyzes current challenges, and proposes corresponding solutions.
Review
Nanoscience & Nanotechnology
Mohammad Mehdi Nazemi et al.
Summary: Near-field electrospinning (NFES) is a production technology for micro- or nanofibers that uses jetting molten polymer or polymer solution. It offers high resolution, simplicity, precision, high throughput, reproducibility, and low costs. NFES can produce ultrafine nanofibers and is useful for small and additive manufacturing. Ongoing development of NFES has potential for further research.
ACS APPLIED BIO MATERIALS
(2022)
Review
Nanoscience & Nanotechnology
Shengda Liu et al.
Summary: Nanozymes, emerging nanomaterials with ideal enzymatic catalytic performance, have shown clear potential to overcome the limitations of natural enzymes. Research on nanozymes has been booming in the past decade, showing a wide range of applications and exceptional catalytic performance, especially in the field of biomedical engineering.
Article
Niyou Wang et al.
Article
Engineering, Biomedical
Ruihua Dong et al.
Summary: The highly stretchable electrode array based on the liquid metal-polymer conductor achieves high mechanical flexibility and good cytocompatibility for neural interfaces. It exhibits high stretchability and excellent cycling stability, allowing for long-term culturing of primary neurons and signal recording, which could significantly advance brain-machine interfaces.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Shreya Mehrotra et al.
Summary: The study utilized a bioink containing carbon nanotubes for bioprinting, showing its regulatory effects on cardiac biomarkers and importance in maintaining cell viability. Through microsphere injection and in vivo implantation experiments, it was found that modulation towards anti-inflammatory M2 phenotype, can extend the time frame for dealing with hostile microenvironments to promote host neovascularization and implant acceptance.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Xuan Liu et al.
Summary: This study demonstrates a static optical projection lithography technology for fast printing of customized high-quality microneedle arrays, achieving the goal of rapid customization of microneedle arrays.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Jingjiang Wei et al.
Summary: Bioinspired hydrogels with self-healing ability, stretchability, 3D printability, and multiple conductivities can serve as integrated strain sensors, exhibiting sensitive responses to subtle pressure changes in the human body.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Engineering, Biomedical
Jianhua Zhang et al.
Summary: In this study, a novel human mesenchymal stem cell (hMSC)-laden GO/alginate/gelatin composite bioink was developed for forming 3D bone mimicking scaffolds. The GO composite bioinks showed improved bioprintability, scaffold fidelity, cell proliferation, osteogenic differentiation, and ECM mineralization. The optimal GO group was 1GO, which demonstrated great potential for 3D bioprinting of bone tissue models and tissue engineering applications.
ACTA BIOMATERIALIA
(2021)
Review
Chemistry, Multidisciplinary
Ben Wang et al.
Summary: This review focuses on the applications of micro-/nanorobots in biomedical engineering, particularly in in vivo diagnosis and intervention. It discusses the design, fabrication, functionalization, actuation, and localization of these robots, as well as their roles in diagnosis, sensing, microsurgery, drug delivery, and wound healing. The review also summarizes the current challenges and future research directions in this field.
ADVANCED MATERIALS
(2021)
Article
Biochemistry & Molecular Biology
Andrew C. Daly et al.
Summary: Bioprinting, an emerging technology for building tissues from scratch, has the potential to revolutionize fundamental understanding in biology by exploring entirely new cell configurations. While commonly used in tissue engineering for therapeutic purposes and drug screening, bioprinting also provides opportunities within biology to investigate cellular crosstalk and morphogenesis. This Primer aims to provide an overview of bioprinting for biologists, focusing on extrusion bioprinting as the most widely used technology, and discussing alternative bioprinting technologies and future opportunities in biology.
Article
Materials Science, Composites
Blessy Joseph et al.
Summary: Plasma modification and surface immobilization of gold nanoparticles onto 3D printed PCL scaffolds significantly enhance the hydrophilicity and mechanical properties, promoting cell attachment and biocompatibility. This simple and cost-effective technique shows great potential for future applications of scaffolds.
COMPOSITES SCIENCE AND TECHNOLOGY
(2021)
Review
Engineering, Multidisciplinary
Weiheng Xu et al.
Summary: The 3D printing technology, also known as additive manufacturing, has great potential in manufacturing but requires further research to develop new mechanisms for multi-material manufacturing. Materials with unique properties, such as particles, can find broad applications in various fields. This review provides an overview of different 3D printing mechanisms and summarizes the processing parameters, advantages, disadvantages, and future challenges.
COMPOSITES PART B-ENGINEERING
(2021)
Article
Chemistry, Physical
Kynan T. Lawlor et al.
Summary: The study demonstrates the use of extrusion-based three-dimensional cellular bioprinting to rapidly and efficiently generate kidney organoids with highly reproducible cell number and viability. This technology not only improves throughput and quality control in organoid production, but also facilitates precise control of structure, enhancing the in vitro and in vivo applications of stem cell-derived human kidney tissue.
Article
Multidisciplinary Sciences
Zheqin Dong et al.
Summary: The method introduced by the authors combines the advantages of 3D printing and polymerization-induced phase separation, enabling the formation of 3D polymer structures with controllable inherent porosity.
NATURE COMMUNICATIONS
(2021)
Article
Nanoscience & Nanotechnology
Junhui Yin et al.
Summary: The engineered composite scaffolds integrating 2D Nb2C MXene show efficient treatment of bone tumor by killing cancer cells and promoting angiogenesis and bone regeneration.
NANO-MICRO LETTERS
(2021)
Review
Chemistry, Multidisciplinary
Amanda K. Pearce et al.
Summary: Shape and size are crucial factors in determining material properties, and the introduction of shape anisotropy at the nanoscale is a potent way to access new properties and functionalities. Recent advancements have allowed for precise control over the morphology and dimensions of anisotropic nanoparticles, leading to the development of materials with unique properties.
NATURE REVIEWS CHEMISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Sultan Aati et al.
Summary: The study demonstrates that 3D printed nanocomposites modified with ZrO2 nanoparticles exhibit superior potential and efficacy as long-term provisional dental restoration materials. The mechanical and physical properties of the composite materials were significantly enhanced by the addition of functionalized ZrO2 nanoparticles, especially in terms of flexural strength and modulus. After accelerated aging in artificial saliva, the overall properties of the nanocomposites were substantially improved, particularly in terms of conversion degree, microhardness, nanoindentation/elasticity, and flexural modulus.
Article
Materials Science, Biomaterials
Ana Iglesias-Mejuto et al.
Summary: 3D printing technology plays a vital role in the manufacturing of functional structures with customized geometries and compositions, especially in the field of tissue engineering.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Editorial Material
Multidisciplinary Sciences
Charlie Schmidt
Article
Chemistry, Physical
Xiewen Wen et al.
Summary: A 3D printing technique has been developed to create high-quality pure silica nanostructures with sub-200 nm resolution and the flexible capability of rare-earth element doping. The printed SiO2 structures show strong photoluminescence at desired wavelengths, making it ideal for building integrated microphotonics. This technique has the potential for exciting applications in three-dimensional micro- and nanophotonics.
Article
Nanoscience & Nanotechnology
Hai-Jun Huang et al.
Summary: This study fabricates a sandwich-structured strain sensor with extraordinarily large stretchability (800%) and self-healing property using liquid metal-like Ag NP ink via 3D printing. The sensor demonstrates excellent sensing performance, including good linearity in two strain ranges, showing potential application in monitoring human knuckle motion. The unique structure of the Ag NP ink, with Ag NPs coalescing together and forming continuous conductive networks through hydrogen bonds, contributes to the sensor's comprehensive performance.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Pharmacology & Pharmacy
Zhen Wang et al.
Summary: Bone regenerative engineering encompasses scaffold design and applications based on electrospinning and 3D bioprinting technologies, aiming to achieve bone tissue regeneration. Electrospun nanofibrous scaffolds and 3D bioprinted scaffolds play crucial roles in bone regeneration, with promising prospects for future development.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Article
Engineering, Biomedical
Mani Diba et al.
Summary: This study presents the 3D printing of novel biomaterial constructs with shape memory behavior using photo-reactive gelatin nanoparticles as colloidal building blocks. The UV-induced covalent interparticle crosslinks significantly enhance the mechanical properties of printed constructs and provide remarkable control over swelling, degradation, and biomolecule release behavior. These novel colloidal inks show great potential to serve as bio-inks for 3D printing of biomaterials with shape-morphing features in tissue engineering and regenerative medicine applications.
Article
Materials Science, Biomaterials
Selwa Boularaoui et al.
Summary: The study optimized GelMA bioinks through concentration and cross-linking time, enhancing printability and biological properties by adding gold nanoparticles (AuNPs) or two-dimensional transition metal carbides (MXene nanosheets). These improvements led to enhanced differentiation of encapsulated cells and enabled printing of highly viable stable constructs.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Valentina Palmieri et al.
Summary: COVID-19 is a major challenge of the 21st century, recommended mask-wearing is crucial for pandemic control, nanotechnologies have brought innovation to mask production, but long-term effects should be carefully monitored.
Article
Multidisciplinary Sciences
Shoupeng Cao et al.
Summary: Aggregation-induced emission (AIE) technology has been a valuable tool in nanoscience, particularly in biomedical fields. Researchers have developed phototactic/phototherapeutic nanomotors using AIEgenic nanomaterials, demonstrating their potential for applications in photodynamic therapy.
NATURE COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
James Utama Surjadi et al.
Summary: This study presents the development of hollow CoCrNi medium-entropy alloy (MEA) nanolattices with high specific energy absorption and resilience, achieved by leveraging size-induced ductility and rationally engineered MEA microstructural defects. These findings suggest a new pathway for lightweight mechanical metamaterials with high strength, toughness, and recoverability for engineering applications.
NPG ASIA MATERIALS
(2021)
Review
Polymer Science
William E. King et al.
Summary: Near-field electrospinning and melt electrowriting involve extruding fibers with the force of an electric field and collecting them before bending occurs, allowing for precise control and customization of scaffold geometry for biomedical applications. Limitations in direct fiber writing include standardization, throughput, and ease of creating complex geometries.
Article
Chemistry, Multidisciplinary
Barbara Zavan et al.
Summary: The study utilized electrospinning to process PCL for the production of bilayered tubular scaffolds, successfully seeding endothelial cells and fibroblasts on different sides for evaluation through techniques like immunofluorescence, SEM, and gene expression. The results confirmed the potential applicability of PCL scaffolds based on electrospun fibers for vascular surgery, as both cell types retained their phenotype on the scaffold surface.
Review
Pharmacology & Pharmacy
Shriya K. Patel et al.
Summary: 3D printing technology has the potential to revolutionize solid dosage form manufacturing, with advantages such as rapid prototyping and the ability to fabricate complex geometries. Different printing technologies and materials can be used to create matrices with varying drug release properties, while methods to manipulate release patterns are critically evaluated.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Review
Chemistry, Multidisciplinary
Halil Tetik et al.
Summary: Aerogels are highly porous structures produced by replacing the liquid solvent of a gel with air, without causing a collapse in the solid network. Additive manufacturing (AM) has been used to fabricate 3D aerogels with customized geometries specific to their applications, showing great promise in various fields such as tissue engineering, electrochemical energy storage, controlled drug delivery, sensing, and soft robotics. Postprinting processes are addressed to achieve desired properties like porosity and mechanical strength through drying and postdrying treatments.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Chemistry, Multidisciplinary
Chengqian Zhang et al.
Summary: Functional magnetic materials have gained attention due to their fast, long-range, and precise response in diverse environments. However, the required materials and structure designs for various functions have increased fabrication difficulties. 3D printing technology offers a powerful and promising approach to manufacturing functional magnetic devices of complex geometries.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Aparna Murali et al.
Summary: Two-dimensional nanomaterials show unique physical, chemical, and biological properties, allowing for enhanced interactions with biomolecules and cells, and have broad potential in biomedical applications.
Article
Chemistry, Multidisciplinary
Yanan Jiang et al.
Summary: Tumor-induced bone loss is a major reason for the failure of bone tumor therapy. A 3D-printed implant was developed to release anti-cancer drugs and growth factors for anti-tumor therapy and osteogenesis. This new approach offers a smart and responsive therapeutic ability for diverse biomedical applications.
Review
Biotechnology & Applied Microbiology
Namit Chaudhary et al.
Summary: mRNA vaccines have been established as a rapid, effective, and safe approach for protecting individuals from infectious diseases, especially during the COVID-19 pandemic. Further research is needed to optimize mRNA vaccine design, delivery, and applications for a range of infectious diseases.
NATURE REVIEWS DRUG DISCOVERY
(2021)
Article
Multidisciplinary Sciences
Cheng Zhou et al.
Summary: In vivo bioprinting has recently emerged as a direct fabrication technique to create artificial tissues and medical devices on target sites within the body. The development of a ferromagnetic soft catheter robot (FSCR) system allows for computer-controlled minimally invasive bioprinting based on magnetic actuation. This innovative system demonstrates the potential for digitally controlled printing with high accuracy on curved surfaces in vivo.
NATURE COMMUNICATIONS
(2021)
Article
Engineering, Biomedical
Johnson V. John et al.
Summary: A new method for fabricating 3D PCL/gelatin nanofiber aerogels with patterned macrochannels and anisotropic microchannels is described. These aerogels show increased cellular infiltration and promote the formation of a microvascular network. Following subcutaneous implantation in rats, the aerogels exhibit enhanced cellular infiltration rates and host tissue integration.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Materials Science, Biomaterials
Nighat Karamat-Ullah et al.
Summary: Scaffold-mediated tissue engineering is crucial for bone tissue regeneration, necessitating careful consideration of biological, microstructural, and mechanical properties. This study developed an antibacterial and biocompatible silica-silk fibroin (SF) gel-based ink for creating three-dimensional hybrid aerogel-based scaffolds, showing promising properties for repairing bone defects.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2021)
Article
Engineering, Biomedical
Zhongyu Jiang et al.
Summary: This study designed and prepared two kinds of PLG-CDDP nanoformulations with detachable PEG, utilizing pH(e) and MMP as trigger factors to prolong circulation time and enhance cell uptake. The smart nanoformulations showed higher antitumor efficacy in vivo, indicating promising prospects for future clinical applications.
BIOACTIVE MATERIALS
(2021)
Review
Biochemistry & Molecular Biology
Huan Cao et al.
Summary: Hydrogel, as a versatile platform, can modulate its physicochemical properties through material engineering to impact cell signaling cascades and fate. Previous studies have revealed the importance of hydrogel properties in influencing cell behaviors and cellular signaling events, providing significant implications for future biomedical applications.
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2021)
Article
Engineering, Biomedical
Yuecheng Cui et al.
Summary: The study introduced cellulose nanocrystals (CNC) to enhance hydrogels for extrusion 3D printing. The addition of CNC significantly improved the thermal stability and mechanical properties of the hydrogels, allowing for high resolution printing with maintained structure and good biocompatibility. This simple and effective strategy enables soft hydrogels to meet the requirements of 3D bioprinting.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2021)
Review
Endocrinology & Metabolism
Herbert Tilg et al.
Summary: Non-alcoholic fatty liver disease (NAFLD) is a global pandemic that particularly affects patients with obesity and type 2 diabetes. The complex interplay between metabolic dysregulation, altered gut microbiome and dysregulated innate and adaptive immunity contributes to the pathology and progression of NAFLD.
Review
Nanoscience & Nanotechnology
Chunxi Zeng et al.
Summary: Nanomaterials play a crucial role in combating the COVID-19 pandemic, including the development of easy, fast, and low-cost diagnostic assays, rapid vaccine development, and research into drug treatments.
Review
Nanoscience & Nanotechnology
Ya Liu et al.
Summary: Chitosan-based nanoparticles are extensively studied as drug delivery systems due to their outstanding biological properties, facilitating improved drug bioavailability in various applications.
Review
Nanoscience & Nanotechnology
Xiangsheng Liu et al.
Summary: Nano-enabled biotechnology holds great promise for disease management, but achieving reproducible production of safe and effective nanotherapeutics requires careful consideration of various factors. Emerging strategies, such as the use of microfluidics systems and iterative CMC optimization, contribute to improving reproducibility and advancing nanomedicine. Personalized and just-in-time nanomedicine may be facilitated by ongoing nano-CMC research efforts.
Review
Nanoscience & Nanotechnology
Chen Zhang et al.
Summary: Disease-oriented theranostic modalities have made significant advancements in the past decade, with a focus on noninvasive treatments using external stimuli sources. Advances in nanomaterial developments and their biomedical translations have shown promise for precision medicine and visualized healthcare resolutions. However, challenges remain in ensuring comprehensive safety issues for human use.
Review
Nanoscience & Nanotechnology
Yan Zu et al.
Summary: Bioinspired Mo-based nanozymes, utilizing molybdenum as a transition metal with variable oxidation states, exhibit tunable enzyme-like activity and multifunctionality by regulating their physicochemical properties. These nanomaterials show great potential for biomedical applications with unique structures and physicochemical features.
Review
Nanoscience & Nanotechnology
Zongrui Tong et al.
Summary: Catalytic therapy using special substances at tumor sites is a promising approach to achieve tumor-specific treatment or enhance the efficacy of other treatments. Utilizing nanomaterials and cascade strategies can significantly improve the effectiveness of catalytic therapy, presenting important implications for cancer treatment.
Review
Nanoscience & Nanotechnology
Armin Geraili et al.
Summary: Advanced polymeric controlled delivery systems are designed to treat chronic diseases by adjusting drug release profiles, but conventional carriers cannot meet the needs of diseases requiring variable drug release patterns. The importance of individualized therapy and the tunable properties of biodegradable polymers are driving the design and manufacturing of controlled drug delivery systems with adjustable release profiles.
Review
Nanoscience & Nanotechnology
Min Xu et al.
Summary: Transition metal-based nanoparticles with unique characteristics and shape effects have attracted attention in biomedicine. Research has focused on developing anisotropic shapes to enhance physicochemical properties and biological activity. Different shape categories of anisotropic transition metal-based nanomaterials offer distinct advantages in biomedical applications.
Review
Engineering, Biomedical
Yi Zhang et al.
Summary: 3D bioprinting technology plays a significant role in fabricating artificial tissue, with a shift towards multi-process composite mode. This evolution requires more complex path planning and process control, challenging traditional CAD/CAM systems.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2021)
Review
Chemistry, Multidisciplinary
Nasuha Rohaizad et al.
Summary: 2D materials, such as transition metal dichalcogenides, Xenes, carbon nitrides, boron nitrides, and MXenes, have diverse applications in biomedical and environmental monitoring, including biosensors, drug delivery, and photothermal therapy. Their properties, such as crystal phases, electrical conductivity, and surface functionalization, play a crucial role in influencing their performance.
CHEMICAL SOCIETY REVIEWS
(2021)
Review
Engineering, Biomedical
Shokouh Attarilar et al.
Summary: This review comprehensively discusses 3D printing technologies for manufacturing metallic implants, categorizing various technologies based on their main properties, introducing effecting parameters, and briefly analyzing the history of AM technology.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2021)
Article
Chemistry, Multidisciplinary
Haibo Ding et al.
ADVANCED FUNCTIONAL MATERIALS
(2020)
Review
Chemistry, Multidisciplinary
Shuang Liu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2020)
Article
Optics
Zejie Yu et al.
LIGHT-SCIENCE & APPLICATIONS
(2020)
Review
Materials Science, Multidisciplinary
Wooram Park et al.
PROGRESS IN MATERIALS SCIENCE
(2020)
Article
Multidisciplinary Sciences
Jiaxing Gong et al.
NATURE COMMUNICATIONS
(2020)
Article
Chemistry, Multidisciplinary
Jie Tao et al.
ADVANCED FUNCTIONAL MATERIALS
(2020)
Review
Chemistry, Multidisciplinary
Hung Pang Lee et al.
Article
Pharmacology & Pharmacy
Ilbey Karakurt et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2020)
Article
Multidisciplinary Sciences
Yuwen Chen et al.
Article
Chemistry, Multidisciplinary
Yan Jie Neriah Tan et al.
JOURNAL OF CONTROLLED RELEASE
(2020)
Article
Nanoscience & Nanotechnology
Erina Baynojir Joyee et al.
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Chemistry, Multidisciplinary
Maha Alafeef et al.
Article
Multidisciplinary Sciences
Junzhe Zhu et al.
NATURE COMMUNICATIONS
(2020)
Article
Multidisciplinary Sciences
Shanyu Zhao et al.
Article
Chemistry, Multidisciplinary
Chiara Grosshaus et al.
Article
Multidisciplinary Sciences
Zhuo-Chen Ma et al.
NATURE COMMUNICATIONS
(2020)
Review
Chemistry, Multidisciplinary
Fernando Soto et al.
Article
Chemistry, Multidisciplinary
Jiumeng Zhang et al.
Article
Multidisciplinary Sciences
Martin Regehly et al.
Review
Engineering, Biomedical
Hua Zhang et al.
BIOACTIVE MATERIALS
(2020)
Review
Materials Science, Multidisciplinary
Karim Khan et al.
JOURNAL OF MATERIALS CHEMISTRY C
(2020)
Review
Nanoscience & Nanotechnology
Wei Cheng et al.
Article
Chemistry, Physical
Erik N. Schaumann et al.
Article
Chemistry, Multidisciplinary
Yanyan Yin et al.
Article
Nanoscience & Nanotechnology
Shivani Sathish et al.
Review
Engineering, Biomedical
Jiumeng Zhang et al.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2020)
Review
Chemistry, Multidisciplinary
Jiajia Xue et al.
Article
Chemistry, Physical
Haitao Cui et al.
Article
Chemistry, Physical
Xiao Yang et al.
Article
Chemistry, Multidisciplinary
Zhibo Zhang et al.
Article
Engineering, Biomedical
Hee-Gyeong Yi et al.
NATURE BIOMEDICAL ENGINEERING
(2019)
Review
Engineering, Biomedical
Yuan Siang Lui et al.
ACTA BIOMATERIALIA
(2019)
Article
Chemistry, Multidisciplinary
Fangyu Zhang et al.
ADVANCED MATERIALS
(2019)
Review
Chemistry, Multidisciplinary
Chandran Murugan et al.
JOURNAL OF CONTROLLED RELEASE
(2019)
Article
Chemistry, Multidisciplinary
Ruodan Xu et al.
JOURNAL OF CONTROLLED RELEASE
(2019)
Review
Nanoscience & Nanotechnology
Simon D. Anderson et al.
NANOSCALE RESEARCH LETTERS
(2019)
Article
Nanoscience & Nanotechnology
Xifeng Liu et al.
ACS APPLIED MATERIALS & INTERFACES
(2019)
Review
Pharmacology & Pharmacy
Khadijeh Ashtari et al.
ADVANCED DRUG DELIVERY REVIEWS
(2019)
Review
Chemistry, Multidisciplinary
Nishtha Panwar et al.
Article
Robotics
Akira Furui et al.
Review
Pharmacology & Pharmacy
Chong Li et al.
ACTA PHARMACEUTICA SINICA B
(2019)
Article
Nanoscience & Nanotechnology
Guo Liang Goh et al.
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Chemistry, Multidisciplinary
Riccardo Tognato et al.
ADVANCED FUNCTIONAL MATERIALS
(2019)
Review
Chemistry, Multidisciplinary
S. K. Sharma et al.
Article
Engineering, Biomedical
Jie Tao et al.
ACTA BIOMATERIALIA
(2019)
Article
Chemistry, Multidisciplinary
Jianhe Guo et al.
Review
Pharmacology & Pharmacy
Xuanyi Ma et al.
ADVANCED DRUG DELIVERY REVIEWS
(2018)
Article
Chemistry, Multidisciplinary
Linda M. Guiney et al.
Editorial Material
Cardiac & Cardiovascular Systems
Alexandra Le Bras
NATURE REVIEWS CARDIOLOGY
(2018)
Article
Multidisciplinary Sciences
Andrey Vyatskikh et al.
NATURE COMMUNICATIONS
(2018)
Article
Polymer Science
Tien Hsi Lee et al.
Review
Food Science & Technology
Diana Oliveira et al.
Review
Nanoscience & Nanotechnology
Stefano Palagi et al.
NATURE REVIEWS MATERIALS
(2018)
Article
Multidisciplinary Sciences
Daniel Oran et al.
Review
Biochemistry & Molecular Biology
Sudipta Senapati et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2018)
Review
Polymer Science
Jing-Jun Wu et al.
CHINESE JOURNAL OF POLYMER SCIENCE
(2018)
Article
Multidisciplinary Sciences
James J. Jun et al.
Review
Polymer Science
Kenry et al.
PROGRESS IN POLYMER SCIENCE
(2017)
Editorial Material
Chemistry, Analytical
Vinay Bhardwaj et al.
Article
Chemistry, Multidisciplinary
Yuan Yang et al.
Article
Materials Science, Multidisciplinary
Raj Kiran et al.
MATERIALS RESEARCH EXPRESS
(2017)
Review
Materials Science, Multidisciplinary
Tailin Xu et al.
APPLIED MATERIALS TODAY
(2017)
Article
Materials Science, Composites
Manik C. Biswas et al.
COMPOSITES COMMUNICATIONS
(2017)
Article
Engineering, Biomedical
Zhi-Qiang Zhang et al.
Article
Engineering, Biomedical
Yongliang Zhang et al.
Review
Pharmacology & Pharmacy
Benjamin M. Luby et al.
ADVANCED DRUG DELIVERY REVIEWS
(2017)
Article
Engineering, Biomedical
Zhi-Qiang Zhang et al.
Article
Chemistry, Multidisciplinary
Jeffrey O'Brien et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2016)
Editorial Material
Multidisciplinary Sciences
Neil Savage
Article
Chemistry, Physical
Xiaoyu Zheng et al.
Article
Chemistry, Physical
A. Sydney Gladman et al.
Correction
Optics
Timo Gissibl et al.
Article
Optics
Timo Gissibl et al.
Editorial Material
Chemistry, Multidisciplinary
Benoit Dubertret et al.
ACCOUNTS OF CHEMICAL RESEARCH
(2015)
Article
Nanoscience & Nanotechnology
Mary Ann B. Meador et al.
ACS APPLIED MATERIALS & INTERFACES
(2015)
Article
Chemistry, Multidisciplinary
Ciro Chiappini et al.
Article
Chemistry, Multidisciplinary
Wei-Chen Huang et al.
ADVANCED MATERIALS
(2015)
Article
Chemistry, Multidisciplinary
Wei Zhu et al.
ADVANCED MATERIALS
(2015)
Article
Biochemistry & Molecular Biology
Sara Gnavi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2015)
Review
Chemistry, Multidisciplinary
Garima Mittal et al.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2015)
Review
Nanoscience & Nanotechnology
Bo Zhou et al.
NATURE NANOTECHNOLOGY
(2015)
Article
Multidisciplinary Sciences
Dimitri Kokkinis et al.
NATURE COMMUNICATIONS
(2015)
Article
Multidisciplinary Sciences
Joshua J. Martin et al.
NATURE COMMUNICATIONS
(2015)
Article
Materials Science, Multidisciplinary
Tao Sun et al.
MATERIALS & DESIGN
(2015)
Review
Chemistry, Multidisciplinary
Jing Zhou et al.
Review
Chemistry, Multidisciplinary
Vasudevanpillai Biju
CHEMICAL SOCIETY REVIEWS
(2014)
Review
Biochemical Research Methods
Alireza Valizadeh et al.
IET NANOBIOTECHNOLOGY
(2014)
Review
Chemistry, Multidisciplinary
Charlene M. Dawidczyk et al.
JOURNAL OF CONTROLLED RELEASE
(2014)
Article
Multidisciplinary Sciences
Xiaoyu Zheng et al.
Article
Multidisciplinary Sciences
Maling Gou et al.
NATURE COMMUNICATIONS
(2014)
Review
Food Science & Technology
Leopoldo Palma et al.
Editorial Material
Chemistry, Multidisciplinary
Chaenyung Cha et al.
Review
Chemistry, Multidisciplinary
Mingsheng Xu et al.
Article
Materials Science, Multidisciplinary
Matteo Monti et al.
Editorial Material
Pharmacology & Pharmacy
Alexander T. Florence et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2011)
Article
Engineering, Biomedical
Rajmohan Bhandari et al.
BIOMEDICAL MICRODEVICES
(2010)
Article
Chemistry, Multidisciplinary
Chieh Chang et al.
Article
Chemistry, Multidisciplinary
Kyungsuk Yum et al.
Article
Polymer Science
Sung Jin Kim et al.
Article
Oncology
M. R. Green et al.
ANNALS OF ONCOLOGY
(2006)
Article
Medicine, General & Internal
A Atala et al.
Article
Chemistry, Multidisciplinary
DH Sun et al.
Article
Multidisciplinary Sciences
S Kawata et al.
