4.2 Article

Case report: Skin protective barrier cream interference in benzethonium chloride method for urine protein measurement in a 6-month-old girl

Journal

ANNALS OF CLINICAL BIOCHEMISTRY
Volume -, Issue -, Pages -

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/00045632231218833

Keywords

Proteins; analytes; inborn errors of metabolism; clinical studies; renal disease

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This case report discusses the interference of using commonly used skin protective barrier cream along with urine collection bags on the benzethonium chloride method for urine protein measurements in a 6-month-old female baby, resulting in falsely elevated results.
This case report describes the positive interference of the commonly used skin protective barrier cream used together with urine collection bags on the benzethonium chloride method for urine protein measurements in a 6-month-old female baby, leading to falsely elevated results. The interference was identified by both artificially mixing urine samples with this cream and comparing the results obtained using the benzethonium chloride method with those obtained using the pyrogallol red method.

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