Exoskeleton Partial-Coated Stem Cells for Infarcted Myocardium Restoring

Article Chemistry, Medicinal

The AmberTools

David A. Case et al.

Summary: AmberTools is a free and open-source collection of programs used for setting up, running, and analyzing molecular simulations. This Application note provides a brief description of the newer features found in AmberTools23.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2023)

Add to Collection

Article Engineering, Biomedical

An injectable conductive hydrogel with dual responsive release of rosmarinic acid improves cardiac function and promotes repair after myocardial infarction

Linghong Zhang et al.

Summary: In this study, a pH/ROS dual-responsive injectable hydrogel was developed to improve the treatment of myocardial infarction (MI). It achieved on-demand drug release in response to the MI microenvironment, exerting anti-inflammatory, anti-apoptotic, and anti-fibrosis effects. The hydrogel also improved conductivity and mechanical strength, restored electrical signal transmission, promoted synchronous contraction of cardiomyocytes, and induced angiogenesis. The multifunctional hydrogel was effective in restoring cardiac function and showed great potential in promoting the repair of infarcted hearts.

BIOACTIVE MATERIALS (2023)

Add to Collection

Review Biochemistry & Molecular Biology

Targeting integrin pathways: mechanisms and advances in therapy

Xiaocong Pang et al.

Summary: Integrins are cell-adhesion receptors that play important roles in cell signaling and communication. Targeting integrins for therapeutic purposes has been challenging due to their complexity and opposing characteristics. Currently, there are only seven approved drugs targeting integrins on the market, but there are ongoing efforts to develop new therapies and diagnostic tools. Understanding the regulatory mechanisms of integrins and addressing unmet clinical needs are crucial for successful development of integrin-targeted therapies.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2023)

Add to Collection

Article Chemistry, Multidisciplinary

Targeting Endogenous Hydrogen Peroxide at Bone Defects Promotes Bone Repair

Jiaying Li et al.

Summary: This study visualizes the spatial and temporal profile of ROS in the bone injury microenvironment using photoacoustic imaging technique for the first time. It demonstrates that the levels of H2O2 increase significantly upon bone injury, peak at a certain stage of bone healing, and gradually decrease towards baseline level. Regulating ROS with hollow manganese dioxide nanoparticles (hMNPs) can promote cell growth and repair in bone injury environments.

ADVANCED FUNCTIONAL MATERIALS (2022)

Add to Collection

Article Engineering, Biomedical

Alleviating Oxidative Injury of Myocardial Infarction by a Fibrous Polyurethane Patch with Condensed ROS-Scavenging Backbone Units

Jieqi Xie et al.

Summary: In this study, a segmented polyurethane material with high efficiency of reactive oxygen species (ROS) elimination was synthesized. Electrospun composite patches made from this material showed antioxidation capacity and ROS-responsive degradation. Implantation of these patches on heart tissue surface reduced ROS level, membrane peroxidation, and cell apoptosis, while decreasing inflammation and fibrosis, leading to improved cardiac functions.

ADVANCED HEALTHCARE MATERIALS (2022)

Add to Collection

Review Chemistry, Multidisciplinary

Development of Innovative Biomaterials and Devices for the Treatment of Cardiovascular Diseases

Yunbing Wang et al.

Summary: Cardiovascular diseases are the leading cause of death worldwide and their burden is increasing. The efficient and reliable treatment of cardiovascular diseases has become an urgent global problem. Implantable biomaterials and devices play a crucial role in treatment and have promising future development directions.

ADVANCED MATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Cell-in-Catalytic-Shell Nanoarchitectonics: Catalytic Empowerment of Individual Living Cells by Single-Cell Nanoencapsulation

Hojae Lee et al.

Summary: This research describes a strategy for imparting living cells with extrinsic catalytic capability through nanoencapsulation, allowing cells to acquire new biochemical functions and enhancing their biological functions. This has important implications for catalytic bioempowerment of living cells.

ADVANCED MATERIALS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Hydrogen-Bonded Organic Framework (HOF)-Based Single-Neural Stem Cell Encapsulation and Transplantation to Remodel Impaired Neural Networks

Dongqin Yu et al.

Summary: This study encapsulates neural stem cells (NSCs) using porous carbon nanospheres (PCNs) and hydrogen-bonded organic frameworks (HOFs) to resist oxidative stress and enhance viability, demonstrating the promotion of neurogenesis and improvement of cognitive function in an Alzheimer's disease (AD) mouse model.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Add to Collection

Review Cell Biology

Pre-Conditioning Methods and Novel Approaches with Mesenchymal Stem Cells Therapy in Cardiovascular Disease

Anthony Matta et al.

Summary: Transplantation of mesenchymal stem cells (MSCs) has shown good clinical outcomes in cardiovascular diseases such as heart failure, cardiomyopathy, and ischemic heart disease. This is attributed to reduced ventricular remodeling, myocardial fibrosis, scar size, and improved endothelial dysfunction. MSCs also exhibit regenerative, pro-angiogenic, anti-apoptotic, and anti-inflammatory effects. This review focuses on different preconditioning methods and novel approaches to optimize the efficacy of MSC therapy.

CELLS (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Effect of the Incorporation of ZIF-8@GO into the Thin-Film Membrane on Salt Rejection and BSA Fouling

Elizabeth Gaobodiwe Masibi et al.

Summary: A series of Zeolitic imidazole framework-8 (ZIF-8) clusters supported on graphene oxide (ZIF-8@GO) nanocomposites were prepared and incorporated into thin film nanofiltration (TFN) membranes. The nanocomposites improved the pure water flux, salt rejection, and fouling resistance of the membranes. The optimal ZIF-8 to GO ratio was determined to achieve the best membrane performance.

MEMBRANES (2022)

Add to Collection

Article Chemistry, Multidisciplinary

A dual crosslinked hydrogel-mediated integrated peptides and BMSC therapy for myocardial regeneration

Zhi Zheng et al.

Summary: The efficacy of myocardial regeneration strategies is hindered by the complex structure of the myocardium, but a dual crosslinking conductive hydrogel has been developed that can provide comprehensive recovery and regeneration of the myocardium through synergistic peptide and cell therapy.

JOURNAL OF CONTROLLED RELEASE (2022)

Add to Collection

Article Engineering, Environmental

Facile pH-responsive injectable polyphenol-europium assembly coordination complex with enhanced antioxidation and angiogenesis for myocardial infarction treatment

Keke Wu et al.

Summary: This study introduces an injectable biomaterial for cardiac tissue regeneration, which is composed of a pH-responsive coordination complex with enhanced antioxidation and angiogenesis properties. The material exhibits good cytocompatibility, promotes angiogenesis, and demonstrates significant functional improvement in a rat model of myocardial infarction.

CHEMICAL ENGINEERING JOURNAL (2022)

Add to Collection

Article Chemistry, Medicinal

The Effect of Surface Composition on the Selective Capture of Atmospheric CO2 by ZIF Nanoparticles: The Case of ZIF-8

Alexsander C. Vendite et al.

Summary: This study investigated the capture of CO2 by ZIF-8 in atmospheric conditions through simulations and calculations. It was found that ZIF-8 selectively captures CO2 and this capture efficiency is dependent on thermodynamic conditions, which can be enhanced by decreasing temperature and/or increasing pressure.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2022)

Add to Collection

Review Nanoscience & Nanotechnology

Rational Design of Intelligent and Multifunctional Dressing to Promote Acute/Chronic Wound Healing

Liping Zhou et al.

Summary: This article summarizes the microenvironment characteristics of various common wounds and discusses how to combine the complex microenvironment with modern advanced technology to design and develop intelligent and multifunctional wound dressings that meet clinical treatment needs.

ACS APPLIED BIO MATERIALS (2022)

Add to Collection

Article Engineering, Biomedical

Improvement of organisms by biomimetic mineralization: A material incorporation strategy for biological modification

Yueqi Zhao et al.

Summary: This review summarizes recent advances in improving biological organisms by integrating them with functional materials through biomimetic mineralization. The successful constructions of various virus-, prokaryotes-, and eukaryotes-material hybrids demonstrate great potentials in vaccine development, cancer treatment, biological photosynthesis, and environmental protection. Challenges and perspectives for the future development of organism-material hybrids are also discussed.

ACTA BIOMATERIALIA (2021)

Add to Collection

Article Nanoscience & Nanotechnology

Nanoscale Zeolitic Imidazolate Framework-8 Activator of Canonical MAPK Signaling for Bone Repair

Xiaomeng Gao et al.

Summary: This study demonstrates that nano ZIF-8 can drive rat bone mesenchymal stem cells differentiation into osteoblasts, with better osteogenic effect compared to ionic conditions of Zn at the same concentration. The cellular uptake mechanisms were revealed to involve caveolae-mediated endocytosis and macropinocytosis. Additionally, transcriptome sequencing identified upregulation of multiple osteogenic pathways, primarily phosphorylating ERK to activate the canonical mitogen-activated protein kinase pathway for promoting osteogenesis.

ACS APPLIED MATERIALS & INTERFACES (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Hopes and Hurdles of Employing Mesenchymal Stromal Cells in the Treatment of Cardiac Fibrosis

Sebastian Neuber et al.

Summary: Excessive cardiac fibrosis is crucial in heart diseases, beneficial for repair in the short term but leading to dysfunction in the long term. MSC therapy has shown promise in reducing fibrosis and improving heart function through anti-fibrotic and regenerative reactions.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Bispecific Antibody Inhalation Therapy for Redirecting Stem Cells from the Lungs to Repair Heart Injury

Mengrui Liu et al.

Summary: This study explores a novel approach utilizing lung resident stem cells for cardiac repair. By specifically designed antibodies, lung HSCs are redirected to the injured heart, promoting endogenous repair mechanisms. This strategy demonstrates increased cardiac function through altered repair mechanisms, and shows safety and effectiveness in a mouse model of myocardial infarction.

ADVANCED SCIENCE (2021)

Add to Collection

Review Oncology

Integrins regulate stemness in solid tumor: an emerging therapeutic target

Jiangling Xiong et al.

Summary: Integrins are adhesion molecules and receptors that regulate cellular functions in response to environmental cues. Dysregulation of integrins is linked to cancer development, and integrins play a crucial role in controlling cancer stem cells and tumor stemness functions.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Partial Coated Stem Cells with Bioinspired Silica as New Generation of Cellular Hybrid Materials

Marta M. Maciel et al.

Summary: By partially coating human adipose-derived mesenchymal stem cells (hASCs) with a hard silica layer, cell survival in suspension conditions is enhanced, leading to a more adherent phenotype. This new protocol not only improves cell handling and application, but also provides a new generation of hybrid materials with functionalization of the silica backpack for various applications in tissue engineering, biosensing, drug delivery, and targeted cell-based therapies.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Chinese herb-crosslinked hydrogel bearing rBMSCs-laden polyzwitterion microgels: Self-adaptive manipulation of micromilieu and stemness maintenance for restoring infarcted myocardium

Yang Liu et al.

Summary: The study developed an injectable hydrogel containing rat bone marrow mesenchymal stem cells for treating myocardial infarction. By modulating the microenvironment to enhance cell survival and therapeutic outcomes, significant improvements in cardiac function and structure were achieved.

NANO TODAY (2021)

Add to Collection

Article Materials Science, Multidisciplinary

Tea polyphenol cytoprotective exoskeleton for living cells

Wei Chen et al.

Summary: The study shows that a cytocompatible shell formed by tea polyphenol and iron ions can retard cell division and growth in harsh conditions, providing cell protection. This coating has a time-dependent suppression effect on cells and serves as a versatile tool for governing external properties of cells.

MATERIALS LETTERS (2021)

Add to Collection

Article Cell Biology

Anoikis resistance in mammary epithelial cells is mediated by semaphorin 7a

Taylor R. Rutherford et al.

Summary: The study reveals that SEMA7A promotes anoikis resistance in mammary epithelial cells and plays a role during mammary gland involution. SEMA7A is primarily expressed in cells expressing alpha 6-integrin, and a decrease in luminal progenitor cells is observed in SEMA7A-/- mice during involution.

CELL DEATH & DISEASE (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Polyphenol-Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery

Yuxin Guo et al.

Summary: Polyphenols, commonly found in plants, have beneficial effects on human health and their use in nanoparticles shows promising potential for various biomedical applications. Their coordination with metal ions forms important complexes with applications in surface modification, bioimaging, drug delivery, and disease treatments. The versatility of polyphenol-containing nanoparticles in different biomedical applications has been demonstrated, with challenges for future research being discussed.

ADVANCED MATERIALS (2021)

Add to Collection

Article Engineering, Biomedical

Engineering hiPSC-CM and hiPSC-EC laden 3D nanofibrous splenic hydrogel for improving cardiac function through revascularization and remuscularization in infarcted heart

Ge Guan et al.

Summary: Researchers developed a splenic extracellular matrix derived hydrogel to efficiently induce human pluripotent stem cells into endothelial and cardiac cells, as well as protect them from oxidative stress damage. In vivo studies showed that this hydrogel improved cardiac function and inhibited fibrosis in infarcted hearts.

BIOACTIVE MATERIALS (2021)

Add to Collection

Article Multidisciplinary Sciences

Stabilization of supramolecular membrane protein-lipid bilayer assemblies through immobilization in a crystalline exoskeleton

Fabian C. Herbert et al.

Summary: This study demonstrates the successful generation and immobilization of metastable lipid, protein-detergent, and protein-lipid supramolecular complexes within a zeolitic-imidazole framework (ZIF) to enhance stability against various stressors. The immobilized complexes exhibit resistance to elevated temperatures, chemical denaturants, aging, and mechanical stresses, maintaining their native morphology, structure, and activity. Immobilizing lipid nanoparticles and lipid-protein assemblies remains challenging due to lipid dynamics and protein instability, but this work shows promise for long-term storage at room temperature.

NATURE COMMUNICATIONS (2021)

Add to Collection

Article Engineering, Biomedical

Polyphenol-assisted facile assembly of bioactive nanoparticles for targeted therapy of heart diseases

Yuantong Qi et al.

Summary: Developing targeted therapy for heart diseases remains a significant challenge. A polyphenol-assisted nanoprecipitation/self-assembly method was developed to easily engineer functional nanoparticles for heart targeting. By using different carrier materials and polyphenols, well-defined nanoparticles with excellent properties can be prepared efficiently. TA-derived nanoparticles showed potent ROS-scavenging activity, especially those produced from a cyclodextrin-derived bioactive material. Moreover, these nanoparticles effectively protected cardiomyocytes from hypoxic-ischemic injury and showed promising therapeutic effects in murine models of heart diseases.

BIOMATERIALS (2021)

Add to Collection

Review Cell & Tissue Engineering

Surfing the clinical trials of mesenchymal stem cell therapy in ischemic cardiomyopathy

Iman Razeghian-Jahromi et al.

Summary: Mesenchymal stem cell (MSC) therapy has shown positive outcomes in clinical trials for heart failure, including scar size reduction, reverse remodeling, and angiogenesis. However, there are still uncertainties regarding the optimal dose, route of administration, timing, and source of stem cells, which are limiting the routine use of MSC therapy in clinical practice.

STEM CELL RESEARCH & THERAPY (2021)

Add to Collection

Review Cell & Tissue Engineering

Application of mesenchymal stem cell sheet to treatment of ischemic heart disease

Dehua Chang et al.

Summary: The review discusses the use of MSC sheets for improving cardiac function and alleviating adverse ventricular remodeling in ischemic heart tissue. Among various types of MSCs, UC-MSCs are highlighted as a promising candidate due to their unique features and ease of isolation and culture.

STEM CELL RESEARCH & THERAPY (2021)

Add to Collection

Review Cell Biology

Integrins: An Important Link between Angiogenesis, Inflammation and Eye Diseases

Malgorzata Mrugacz et al.

Summary: Integrins are a group of cell adhesion molecules that play crucial roles in cell attachment, signal transduction, infection, inflammation and angiogenesis. They are important in eye diseases and may serve as promising therapeutic targets for treating such disorders.

CELLS (2021)

Add to Collection

Review Biotechnology & Applied Microbiology

Intervertebral Disk Degeneration: The Microenvironment and Tissue Engineering Strategies

Yiming Dou et al.

Summary: IVDD is a leading cause of disability, with inevitable degeneration and complex mechanisms. Current therapies focus on symptom relief rather than intrinsic regeneration of IVD. Tissue engineering shows promise in restoring a healthy microenvironment and promoting IVD regeneration, requiring a combination of strategies for personalized therapeutic approaches.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

Add to Collection

Review Cell & Tissue Engineering

State-of-play for cellular therapies in cardiac repair and regeneration

Ramana Vaka et al.

Summary: This article discusses the current state of cellular therapies for cardiac repair and regeneration, outlining the progression of new ideas from preclinical literature to ongoing clinical trials. Recent data supporting the mechanics and mechanisms of myogenic and paracrine therapies are evaluated in the context of long-term cardiac engraftment, informing on promising new approaches for future avenues in the field.

STEM CELLS (2021)

Add to Collection

Article Chemistry, Physical

ff19SB: Amino-Acid-Specific Protein Backbone Parameters Trained against Quantum Mechanics Energy Surfaces in Solution

Chuan Tian et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Protective effect of Nelumbo nucifera (Gaertn.) against H2O2-induced oxidative stress on H9c2 cardiomyocytes

Rajendran Harishkumar et al.

MOLECULAR BIOLOGY REPORTS (2020)

Add to Collection

Review Multidisciplinary Sciences

Nanobiohybrids: Materials approaches for bioaugmentation

Ziyi Guo et al.

SCIENCE ADVANCES (2020)

Add to Collection

Article Nanoscience & Nanotechnology

ZIF-8-Modified Multifunctional Bone-Adhesive Hydrogels Promoting Angiogenesis and Osteogenesis for Bone Regeneration

Yanhua Liu et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Add to Collection

Article Pharmacology & Pharmacy

Mesenchymal Stem Cells in Cardiac Repair: Effects on Myocytes, Vasculature, and Fibroblasts

Samuel J. White et al.

CLINICAL THERAPEUTICS (2020)

Add to Collection

Article Engineering, Chemical

Hydrophilic yolk-shell ZIF-8 modified polyamide thin-film nanocomposite membrane with improved permeability and selectivity

Meng-Ping Li et al.

SEPARATION AND PURIFICATION TECHNOLOGY (2020)

Add to Collection

Article Chemistry, Multidisciplinary

SupraCells: Living Mammalian Cells Protected within Functional Modular Nanoparticle-Based Exoskeletons

Wei Zhu et al.

ADVANCED MATERIALS (2019)

Add to Collection

Review Cell Biology

Thrombogenic Risk Induced by Intravascular Mesenchymal Stem Cell Therapy: Current Status and Future Perspectives

Louise Coppin et al.

CELLS (2019)

Add to Collection

Article Cell & Tissue Engineering

Combinatorial treatment of acute myocardial infarction using stem cells and their derived exosomes resulted in improved heart performance

Peisen Huang et al.

STEM CELL RESEARCH & THERAPY (2019)

Add to Collection

Article Engineering, Biomedical

Anti-oxidant activity reinforced reduced graphene oxide/alginate microgels: Mesenchymal stem cell encapsulation and regeneration of infarcted hearts

Goeun Choe et al.

BIOMATERIALS (2019)

Add to Collection

Article Biochemistry & Molecular Biology

Acidic pHe regulates cytoskeletal dynamics through conformational integrin β1 activation and promotes membrane protrusion

Shun Li et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)

Add to Collection

Article Medicine, Research & Experimental

Integrin alpha5beta1 suppresses rBMSCs anoikis and promotes nitric oxide production

Hai-ying Chen et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Add to Collection

Article Cell Biology

Stromal-Cell-Derived Factor (SDF) 1-Alpha Overexpression Promotes Bone Regeneration by Osteogenesis and Angiogenesis in Osteonecrosis of the Femoral Head

Fan Yang et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

Add to Collection

Article Cardiac & Cardiovascular Systems

New Paradigms in Cell Therapy: Repeated Dosing, Intravenous Delivery, Immunomodulatory Actions, and New Cell Types

Marcin Wysoczynki et al.

CIRCULATION RESEARCH (2018)

Add to Collection

Review Chemistry, Multidisciplinary

Stimuli-responsive nanocarriers for delivery of bone therapeutics - Barriers and progresses

Pedro Lavrador et al.

JOURNAL OF CONTROLLED RELEASE (2018)

Add to Collection

Review Cell & Tissue Engineering

Concise Review: Is Cardiac Cell Therapy Dead? Embarrassing Trial Outcomes and New Directions for the Future

Jun-Nan Tang et al.

STEM CELLS TRANSLATIONAL MEDICINE (2018)

Add to Collection

Review Cell Biology

Integrin Activation: Implications for Axon Regeneration

Menghon Cheah et al.

CELLS (2018)

Add to Collection

Article Engineering, Biomedical

Targeting protein and peptide therapeutics to the heart via tannic acid modification

Mikyung Shin et al.

NATURE BIOMEDICAL ENGINEERING (2018)

Add to Collection

Article Multidisciplinary Sciences

Precursor proadrenomedullin influences cardiomyocyte survival and local inflammation related to myocardial infarction

Svenja Hinrichs et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Add to Collection

Article Multidisciplinary Sciences

Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction

Benjamin Steinhorn et al.

NATURE COMMUNICATIONS (2018)

Add to Collection

Review Cell & Tissue Engineering

Safety and Efficacy of Adult Stem Cell Therapy for Acute Myocardial Infarction and Ischemic Heart Failure (SafeCell Heart): A Systematic Review and Meta-Analysis

Manoj M. Lalu et al.

STEM CELLS TRANSLATIONAL MEDICINE (2018)

Add to Collection

Review Oncology

Every step of the way: integrins in cancer progression and metastasis

Hellyeh Hamidi et al.

NATURE REVIEWS CANCER (2018)

Add to Collection

Review Pediatrics

Elementary immunology: Na+ as a regulator of immunity

Valentin Schatz et al.

PEDIATRIC NEPHROLOGY (2017)

Add to Collection

Review Biotechnology & Applied Microbiology

Cellular mechanisms underlying cardiac engraftment of stem cells

Pushpinder Kanda et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2017)

Add to Collection

Review Biotechnology & Applied Microbiology

Mesenchymal stem cell therapy: A promising cell-based therapy for treatment of myocardial infarction

Ayman El-Sayed Shafei et al.

JOURNAL OF GENE MEDICINE (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization

Jia Niu et al.

NATURE CHEMISTRY (2017)

Add to Collection

Article Multidisciplinary Sciences

The extracellular matrix protein Edil3 stimulates osteoblast differentiation through the integrin α5β1/ERK/Runx2 pathway

Sin-Hye Oh et al.

PLOS ONE (2017)

Add to Collection

Article Neurosciences

SDF-1 overexpression by mesenchymal stem cells enhances GAP-43-positive axonal growth following spinal cord injury

Andrew Nathaniel Stewart et al.

RESTORATIVE NEUROLOGY AND NEUROSCIENCE (2017)

Add to Collection

Article Medicine, Research & Experimental

Heparin improves BMSC cell therapy: Anticoagulant treatment by heparin improves the safety and therapeutic effect of bone marrow-derived mesenchymal stem cell cytotherapy

Li Liao et al.

THERANOSTICS (2017)

Add to Collection

Review Cell & Tissue Engineering

Optimizing stem cells for cardiac repair: Current status and new frontiers in regenerative cardiology

Shant Der Sarkissian et al.

WORLD JOURNAL OF STEM CELLS (2017)

Add to Collection

Article Engineering, Biomedical

Spheroidal formation preserves human stem cells for prolonged time under ambient conditions for facile storage and transportation

Bin Jiang et al.

BIOMATERIALS (2017)

Add to Collection

Article Biochemical Research Methods

Reactome pathway analysis: a high-performance in-memory approach

Antonio Fabregat et al.

BMC BIOINFORMATICS (2017)

Add to Collection

Review Biochemistry & Molecular Biology

Stem cell death and survival in heart regeneration and repair

Eltyeb Abdelwahid et al.

APOPTOSIS (2016)

Add to Collection

Review Engineering, Biomedical

Engineering Stem Cells for Biomedical Applications

Perry T. Yin et al.

ADVANCED HEALTHCARE MATERIALS (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Improvement of Biological Organisms Using Functional Material Shells

Zhaoming Liu et al.

ADVANCED FUNCTIONAL MATERIALS (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Metal-Organic Framework Coatings as Cytoprotective Exoskeletons for Living Cells

Kang Liang et al.

ADVANCED MATERIALS (2016)

Add to Collection

Article Engineering, Biomedical

Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis

Shibin Feng et al.

BIOMATERIALS (2016)

Add to Collection

Review Biotechnology & Applied Microbiology

Stem cells and injectable hydrogels: Synergistic therapeutics in myocardial repair

Mohammadmajid Sepantafar et al.

BIOTECHNOLOGY ADVANCES (2016)

Add to Collection

Article Biochemistry & Molecular Biology

Evidence for Pro-angiogenic Functions of VEGF-Ax

Hong Xin et al.

CELL (2016)

Add to Collection

Article Cardiac & Cardiovascular Systems

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure

Rosalinda Madonna et al.

EUROPEAN HEART JOURNAL (2016)

Add to Collection

Article Cardiac & Cardiovascular Systems

Intramyocardial transplantation of mesenchymal stromal cells for chronic myocardial ischemia and impaired left ventricular function: Results of the MESAMI 1 pilot trial

D. Guijarro et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2016)

Add to Collection

Article Multidisciplinary Sciences

Relating conformation to function in integrin α5β1

Yang Su et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Add to Collection

Review Rheumatology

Stem cell therapy for intervertebral disc regeneration: obstacles and solutions

Daisuke Sakai et al.

NATURE REVIEWS RHEUMATOLOGY (2015)

Add to Collection

Review Cell Biology

Cell Adhesion and Long-Term Survival of Transplanted Mesenchymal Stem Cells: A Prerequisite for Cell Therapy

Seahyoung Lee et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)

Add to Collection

Article Chemistry, Multidisciplinary

Tackling Cell Transplantation Anoikis: An Injectable, Shape Memory Cryogel Microcarrier Platform Material for Stem Cell and Neuronal Cell Growth

Ben Newland et al.

SMALL (2015)

Add to Collection

Article Multidisciplinary Sciences

Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation

W. K. Eddie Ip et al.

NATURE COMMUNICATIONS (2015)

Add to Collection

Article Cell Biology

Direct intercellular communications dominate the interaction between adipose-derived MSCs and myofibroblasts against cardiac fibrosis

Xiaokang Li et al.

PROTEIN & CELL (2015)

Add to Collection

Review Cell & Tissue Engineering

Physical, Spatial, and Molecular Aspects of Extracellular Matrix of In Vivo Niches and Artificial Scaffolds Relevant to Stem Cells Research

Maria Akhmanova et al.

STEM CELLS INTERNATIONAL (2015)

Add to Collection

Review Biochemistry & Molecular Biology

Reactive Oxygen Species in Inflammation and Tissue Injury

Manish Mittal et al.

ANTIOXIDANTS & REDOX SIGNALING (2014)

Add to Collection

Article Instruments & Instrumentation

AtomicJ: An open source software for analysis of force curves

Pawel Hermanowicz et al.

REVIEW OF SCIENTIFIC INSTRUMENTS (2014)

Add to Collection

Article Cell Biology

Concentration-dependent wrestling between detrimental and protective effects of H2O2 during myocardial ischemia/reperfusion

Z-H Wang et al.

CELL DEATH & DISEASE (2014)

Add to Collection

Article Oncology

Bone marrow-derived mesenchymal stem cells enhance angiogenesis via their α6β1 integrin receptor

Bita Carrion et al.

EXPERIMENTAL CELL RESEARCH (2013)

Add to Collection

Review Chemistry, Physical

Stimuli-responsive nanocarriers for drug delivery

Simona Mura et al.

NATURE MATERIALS (2013)

Add to Collection

Review Cell Biology

Mesenchymal Stem Cell Therapy for Cardiac Inflammation: Immunomodulatory Properties and the Influence of Toll-Like Receptors

F. van den Akker et al.

MEDIATORS OF INFLAMMATION (2013)

Add to Collection

Article Biochemistry & Molecular Biology

Resveratrol protects adult cardiomyocytes against oxidative stress mediated cell injury

A. Movahed et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2012)

Add to Collection

Review Cardiac & Cardiovascular Systems

The SDF-1/CXCR4 axis in stem cell preconditioning

Chiara Cencioni et al.

CARDIOVASCULAR RESEARCH (2012)

Add to Collection

Article Biochemistry & Molecular Biology

c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

Zuqin Nie et al.

CELL (2012)

Add to Collection

Article Cell Biology

Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

Masamichi Nagae et al.

JOURNAL OF CELL BIOLOGY (2012)

Add to Collection

Review Cardiac & Cardiovascular Systems

Myocardial edema: A translational view

David Garcia-Dorado et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)

Add to Collection

Review Oncology

Anoikis: an emerging hallmark in health and diseases

M. L. Taddei et al.

JOURNAL OF PATHOLOGY (2012)

Add to Collection

Review Cell Biology

Repair mechanisms of bone marrow mesenchymal stem cells in myocardial infarction

Zhuzhi Wen et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)

Add to Collection

Review Chemistry, Multidisciplinary

Enhancing cell therapies from the outside in: Cell surface engineering using synthetic nanomaterials

Matthias T. Stephan et al.

NANO TODAY (2011)

Add to Collection

Review Polymer Science

Hydrogels for Cardiac Tissue Engineering

Zhenqing Li et al.

POLYMERS (2011)

Add to Collection

Review Cell & Tissue Engineering

Stem Cells for Cardiac Repair: Status, Mechanisms, and New Strategies

Ren Mingliang et al.

STEM CELLS INTERNATIONAL (2011)

Add to Collection

Review Cardiac & Cardiovascular Systems

Transcapillary exchange: role and importance of the interstitial fluid pressure and the extracellular matrix

Rolf K. Reed et al.

CARDIOVASCULAR RESEARCH (2010)

Add to Collection

Review Biotechnology & Applied Microbiology

Modification of mesenchymal stem cells for cardiac regeneration

Heesang Song et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2010)

Add to Collection

Review Cell Biology

Cell survival and redistribution after transplantation into damaged myocardium

Hao Zhang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)

Add to Collection

Article Biochemical Research Methods

Quantifying cellular adhesion to extracellular matrix components by single-cell force spectroscopy

Jens Friedrichs et al.

NATURE PROTOCOLS (2010)

Add to Collection

Article Cardiac & Cardiovascular Systems

OPINION Myocardial edema-a new clinical entity?

Matthias G. Friedrich

NATURE REVIEWS CARDIOLOGY (2010)

Add to Collection

Article Cardiac & Cardiovascular Systems

Preconditioning and Stem Cell Survival

Husnain Kh Haider et al.

JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH (2010)

Add to Collection

Article Cardiac & Cardiovascular Systems

Noninvasive Quantification and Optimization of Acute Cell Retention by In Vivo Positron Emission Tomography After Intramyocardial Cardiac-Derived Stem Cell Delivery

John Terrovitis et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)

Add to Collection

Article Cardiac & Cardiovascular Systems

Tracking cardiac engraftment and distribution of implanted bone marrow cells: Comparing intra-aortic, intravenous, and intramyocardial delivery

Shu-Hong Li et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2009)

Add to Collection

Review Physiology

Physiology of Cell Volume Regulation in Vertebrates

Else K. Hoffmann et al.

PHYSIOLOGICAL REVIEWS (2009)

Add to Collection

Article Cardiac & Cardiovascular Systems

Stromal cell-derived factor-1α is cardioprotective after myocardial infarction

Ankur Saxena et al.

CIRCULATION (2008)

Add to Collection

Review Chemistry, Multidisciplinary

A review of stimuli-responsive nanocarriers for drug and gene delivery

Srinivas Ganta et al.

JOURNAL OF CONTROLLED RELEASE (2008)

Add to Collection

Review Cardiac & Cardiovascular Systems

Systems approaches to preventing transplanted cell death in cardiac repair

Thomas E. Robey et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)

Add to Collection

Article Cardiac & Cardiovascular Systems

Intravenously injected mesenchymal stem cells home to viable myocardium after coronary occlusion and preserve systolic function without altering infarct size

Robert A. Boomsma et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2007)

Add to Collection

Article Chemistry, Multidisciplinary

Coating of human mesenchymal cells in 3D culture with bioinorganic nanoparticles promotes osteoblastic differentiation and gene transfection

Rosanna Gonzalez-McQuire et al.

ADVANCED MATERIALS (2007)

Add to Collection

Article Pharmacology & Pharmacy

Antioxidant effects of ginsenoside Re in cardiomyocytes

JT Xie et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2006)

Add to Collection

Review Cell Biology

Intracellular water homeostasis and the mammalian cellular osmotic stress response

SN Ho

JOURNAL OF CELLULAR PHYSIOLOGY (2006)

Add to Collection

Article Cardiac & Cardiovascular Systems

Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis

N Nagaya et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)

Add to Collection

Article Medicine, General & Internal

Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy

AT Askari et al.

LANCET (2003)

Add to Collection

Article Cardiac & Cardiovascular Systems

Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium - Feasibility, cell migration, and body distribution

IM Barbash et al.

CIRCULATION (2003)

Add to Collection

Article Cell Biology

Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

MJ Reginato et al.

NATURE CELL BIOLOGY (2003)

Add to Collection

Article Cell & Tissue Engineering

Why do cultured transplanted myoblasts die in vivo?: DNA quantification shows enhanced survival of donor male myoblasts in host mice depleted of CD4+ and CD8+ cells or NK1.1+ cells

SI Hodgetts et al.

CELL TRANSPLANTATION (2000)

Add to Collection

Exoskeleton Partial-Coated Stem Cells for Infarcted Myocardium Restoring

Related references

Export Citation

Share Paper