4.3 Review

Polymorphisms in the Runx2 and osteocalcin genes affect BMD in postmenopausal women: a systematic review and meta-analysis

Related references

Note: Only part of the references are listed.
Article Endocrinology & Metabolism

Association between SEMA3A signaling pathway genes and BMD/OP risk: An epidemiological and experimental study

Hao-long Zhou et al.

Summary: This study found that genetic variants in NRP1 and PLXNA2 genes are associated with osteoporosis risk and bone mineral density. The NRP1 rs180868035 variant affects bone metabolism by influencing the function of osteoblasts and osteoclasts.

FRONTIERS IN ENDOCRINOLOGY (2022)

Article Dentistry, Oral Surgery & Medicine

Cleidocranial dysplasia and novel RUNX2 variants: dental, craniofacia and osseous manifestations

Sermporn Thaweesapphithak et al.

Summary: This study characterizes the phenotypes and identifies variants causing CCD in five unrelated patients and their family members. The results show the effectiveness of exome sequencing in detecting mutations across different ethnicities. Additionally, the study expands the phenotypic and genotypic spectra of RUNX2 and uncovers new features and variants associated with CCD.

JOURNAL OF APPLIED ORAL SCIENCE (2022)

Article Obstetrics & Gynecology

The importance of NFκB1 rs4648068 and RUNX2 rs7771980 polymorphisms in bone metabolism of postmenopausal Polish women

Anna Bogacz et al.

Summary: The study revealed a certain association between the distribution of polymorphisms in the NF kappa B1 and RUNX2 genes and the risk of osteoporosis, especially the NF kappa B1 gene rs4648068 polymorphism's link to the development of osteoporosis.

GINEKOLOGIA POLSKA (2021)

Review Dentistry, Oral Surgery & Medicine

What is the function of osteocalcin?

Toshihisa Komori

JOURNAL OF ORAL BIOSCIENCES (2020)

Article Endocrinology & Metabolism

Joint Association Analysis Identified 18 New Loci for Bone Mineral Density

Yu-Fang Pei et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2019)

Review Biochemistry & Molecular Biology

Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2

Toshihisa Komori

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Oncology

Runx2 overexpression compromises bone quality in acromegalic patients

Maria Teresa Valenti et al.

ENDOCRINE-RELATED CANCER (2018)

Article Biochemistry & Molecular Biology

Osteocalcin Mediates Biomineralization during Osteogenic Maturation in Human Mesenchymal Stromal Cells

Yu-Tzu Tsao et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Endocrinology & Metabolism

The association between genetic variants of RUNX2, ADIPOQ and vertebral fracture in Korean postmenopausal women

Kyong-Chol Kim et al.

JOURNAL OF BONE AND MINERAL METABOLISM (2015)

Article Endocrinology & Metabolism

Loss of Runx2 in Committed Osteoblasts Impairs Postnatal Skeletogenesis

Mitra D. Adhami et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2015)

Article Multidisciplinary Sciences

Genetic Analysis of High Bone Mass Cases from the BARCOS Cohort of Spanish Postmenopausal Women

Patricia Sarrion et al.

PLOS ONE (2014)

Article Medicine, General & Internal

Gene promoter polymorphism of RUNX2 and risk of osteoporosis in postmenopausal Indonesian women

Elza I. Auerkari et al.

SAGE OPEN MEDICINE (2014)

Article Obstetrics & Gynecology

Vitamin D receptor Fok I polymorphism is associated with low bone mineral density in postmenopausal women: a meta-analysis focused on populations in Asian countries

Dewei Wang et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2013)

Article Endocrinology & Metabolism

Functional Relevance of the BMD-Associated Polymorphism rs312009: Novel Involvement of RUNX2 in LRP5 Transcriptional Regulation

Lidia Agueda et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2011)

Article Endocrinology & Metabolism

Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men

J. M. Zmuda et al.

OSTEOPOROSIS INTERNATIONAL (2011)

Article Endocrinology & Metabolism

Common polymorphisms rather than rare genetic variants of the Runx2 gene are associated with femoral neck BMD in Spanish women

Begona Pineda et al.

JOURNAL OF BONE AND MINERAL METABOLISM (2010)

Article Endocrinology & Metabolism

Osteocalcin Gene Polymorphisms Influence Concentration of Serum Osteocalcin and Enhance Fracture Identification

Fiona McGuigan et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2010)

Article Cell Biology

Bone Loss Induced by Runx2 Over-Expression in Mice Is Blunted by Osteoblastic Over-Expression of TIMP-1

Corinne Schiltz et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2010)

Article Endocrinology & Metabolism

Association of a RUNX2 Promoter Polymorphism with Bone Mineral Density in Postmenopausal Korean Women

Hee-Jung Lee et al.

CALCIFIED TISSUE INTERNATIONAL (2009)

Review Rheumatology

Genetic studies in osteoporosis - the end of the beginning

Emma L. Duncan et al.

ARTHRITIS RESEARCH & THERAPY (2008)

Article Endocrinology & Metabolism

Promoter 2-1025 T/C polymorphism in the RUNX2 gene is associated with femoral neck BMD in Spanish postmenopausal women

Mariona Bustamante et al.

CALCIFIED TISSUE INTERNATIONAL (2007)

Article Endocrinology & Metabolism

Heritability of BMD of femoral neck and lumbar spine:: A multivariate twin study of Finnish men

Tapio Videman et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2007)

Review Cell Biology

Genetic regulation of bone mass and susceptibility to osteoporosis

Stuart H. Ralston et al.

GENES & DEVELOPMENT (2006)

Article Obstetrics & Gynecology

Relationship of osteocalcin and matrix Gla protein gene polymorphisms to serum osteocalcin levels and bone mineral density in postmenopausal Korean women

JG Kim et al.

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2006)

Article Endocrinology & Metabolism

Mutations and promoter SNPs in RUNX2, a transcriptional regulator of bone formation

D Napierala et al.

MOLECULAR GENETICS AND METABOLISM (2005)

Article Biochemistry & Molecular Biology

Lymphoid enhancer factor-1 and β-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

RA Kahler et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Endocrinology & Metabolism

Osteocalcin gene polymorphism is related to bone density in healthy adolescent females

A Gustavsson et al.

OSTEOPOROSIS INTERNATIONAL (2000)