☆ 4.8 Article

Type I Photosensitizer Targeting Glycans: Overcoming Biofilm Resistance by Inhibiting the Two-Component System, Quorum Sensing, and Multidrug Efflux

ADVANCED MATERIALS (2023)

Related references

Note: Only part of the references are listed.
Article Chemistry, Analytical

Molecular engineering to construct thieno[3,2-c]pyridinium based photosensitizers for mitochondrial polarity imaging and photodynamic anticancer therapy

Ming -Yu Wu et al.

Summary: This study designed and synthesized a series of thieno[3,2-c]pyridinium-based near-infrared aggregation-induced emission photosensitizers (AIE PSs) for targeting mitochondria. LIQ-TPA-DTZ can sensitively detect mitochondrial polarity changes in living cells and trigger the mitochondrial apoptosis pathway to efficiently photodynamic kill cancer cells and restrain tumor growth in vivo.

SENSORS AND ACTUATORS B-CHEMICAL (2023)

Add to Collection
Article Nanoscience & Nanotechnology

Molecular Charge and Antibacterial Performance Relationships of Aggregation-Induced Emission Photosensitizers

Jia-Li Wang et al.

Summary: Bacterial infections remain a major cause of morbidity worldwide due to drug resistance. Photodynamic therapy (PDT) offers a promising solution, but current photosensitizers (PSs) have broad-spectrum antibacterial effects and undesirable side effects. In this study, we synthesized aggregation-induced emission (AIE)-active PSs with varying charges and found that different charges influenced their antibacterial effects. Among the derivatives, TBTCP-SF lost its ability to bind and ablate bacteria, while TBTCP-QY and TBTCP-PEG showed enhanced binding and antibacterial activity. TBTCP-PEG significantly eliminated methicillin-resistant Staphylococcus aureus (MRSA) in vitro and in vivo. This work provides insights into using AIE-active PSs for targeted and efficient photodynamic ablation of bacteria.

ACS APPLIED MATERIALS & INTERFACES (2023)

Add to Collection
Article Nanoscience & Nanotechnology

Mechanically Robust Dissolving Microneedles Made of Supramolecular Photosensitizers for Effective Photodynamic Bacterial Biofilm Elimination

Hua Wang et al.

Summary: Antimicrobial photodynamic therapy (PDT) is a promising strategy for eradicating biofilms, but its efficacy is hindered by the low solubility and poor penetration of photosensitizers (PSs) into the biofilms. This study develops a dissolving microneedle (DMN) patch composed of a supramolecular PS for enhanced biofilm penetration and eradication. The DMN patch can efficiently penetrate the biofilms, allowing for optimal photodynamic elimination of bacterial biofilms. In addition, the DMN patch shows good biosafety in vivo for eradicating Staphylococcus aureus biofilm infection.

ACS APPLIED MATERIALS & INTERFACES (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Inhibiting Quorum Sensing by Active Targeted pH-Sensitive Nanoparticles for Enhanced Antibiotic Therapy of Biofilm-Associated Bacterial Infections

Yongcheng Chen et al.

Summary: This research focuses on the development of pH-sensitive curcumin-loaded nanoparticles for inhibiting quorum sensing (QS) and enhancing antibiotic therapy. The nanoparticles show enhanced biofilm penetration and increased bactericidal performance against antibiotics. Additionally, they can selectively accumulate in bacteria-infected tissues through active targeting. This research offers a promising approach to enhance the therapeutic effects of quorum sensing inhibitors and improve antibiotic treatment for biofilm-associated bacterial infections.

ACS NANO (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Efficient NIR-II Type-I AIE Photosensitizer for Mitochondria-Targeted Photodynamic Therapy through Synergistic Apoptosis-Ferroptosis

Jiabao Zhuang et al.

Summary: This article describes an organic near-infrared II photosensitizer (TPEQM-DMA) with potential to overcome the hypoxia obstacle in photodynamic therapy. TPEQM-DMA can produce superoxide anion and hydroxyl radical through a low-O2-dependent type-I photochemical process, leading to disruption of cellular redox homeostasis, mitochondrial dysfunction, and increased peroxidized lipids, inducing cellular apoptosis and ferroptosis. TPEQM-DMA nanoparticles were prepared to improve its pharmacological properties and showed promising NIR-II fluorescence imaging-guided photodynamic therapy effect in vivo for tumors.

ACS NANO (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Raspberry-like gold nanozyme-hybrid liposomes for hypoxia-enhanced biofilm eradication

Lingyun Zou et al.

Summary: Bacterial biofilm-associated infection is a major threat to global public health due to antibiotic resistance. This study repurposes a hypoxia-activated anticancer drug, tirapazamine (TPZ), to treat biofilm-associated infections. A hypoxia-enhanced strategy is used to improve the efficacy of TPZ by encapsulating it into raspberry-like gold nanoparticle-hybrid liposomes (Lip@Au-TPZ). The gold nanoparticles act as nanozymes to catalyze glucose oxidation and aggravate biofilm hypoxia, leading to the eradication of biofilms.

NANO TODAY (2023)

Add to Collection
Article Engineering, Biomedical

Visual Multifunctional Aggregation-Induced Emission-Based Bacterial Cellulose for Killing of Multidrug-Resistant Bacteria

Zipeng Shen et al.

Summary: To address the issue of multidrug-resistant (MDR) bacteria-related wound infections, researchers have developed a new antibacterial wound dressing that can prevent MDR bacteria infection and promote wound healing. The composite of aggregation-induced emission (AIE) molecule BITT and bacterial cellulose (BC) shows good transparency and allows for monitoring the wound healing process. The BC-BITT composites exhibit photodynamic and photothermal synergistic antibacterial effects under 660 nm laser irradiation and demonstrate excellent wound healing performance in a mouse full-thickness skin wound model infected by MDR bacteria, with negligible toxicity. This work provides a new approach for treating clinically troublesome wound infections.

ADVANCED HEALTHCARE MATERIALS (2023)

Add to Collection
Article Chemistry, Multidisciplinary

A Membrane-Targeted Photosensitizer Prevents Drug Resistance and Induces Immune Response in Treating Candidiasis

Ming-Yu Wu et al.

Summary: Translation: Candida albicans, a widespread fungus in humans, causes various types of candidiasis. A novel membrane-targeted photosensitizer, TBTCP-QY, is developed for effective treatment of candidiasis. TBTCP-QY can effectively target oral candidiasis and vulvovaginal candidiasis, induce immune response, relieve inflammation, and promote wound healing to combat infections caused by clinically isolated fluconazole-resistant strains.

ADVANCED SCIENCE (2023)

Add to Collection
Article Engineering, Biomedical

Regulating the bacterial oxygen microenvironment via a perfluorocarbon-conjugated bacteriochlorin for enhanced photodynamic antibacterial efficacy

Mengsi Wu et al.

Summary: Photodynamic therapy is an effective antibacterial treatment, but it often suffers from oxygen limitation. This study developed an oxygen-tunable nanoplatform FBC-F, which showed enhanced antibacterial efficacy in vitro and in vivo.

ACTA BIOMATERIALIA (2022)

Add to Collection
Review Chemistry, Multidisciplinary

Chemical Reporters for Bacterial Glycans: Development and Applications

Nicholas Banahene et al.

Summary: This article reviews the physiological functions of bacterial glycans and the development and applications of chemical reporters targeting bacterial glycans, including their use in diagnostics, therapeutics, and research.

CHEMICAL REVIEWS (2022)

Add to Collection
Article Chemistry, Medicinal

Modular Synthetic Routes to Fluorine-Containing Halogenated Phenazine and Acridine Agents That Induce Rapid Iron Starvation in Methicillin-Resistant Staphylococcus aureus Biofilms

Ke Liu et al.

Summary: This study reports synthetic routes to fluorine-containing halogenated phenazine and halogenated acridine agents and investigates their effects against Gram-positive pathogens and biofilms. The results demonstrate significant antibacterial and biofilm-killing activities of these compounds, possibly through iron starvation.

ACS INFECTIOUS DISEASES (2022)

Add to Collection
Article Chemistry, Multidisciplinary

Cationization-Enhanced Type I and Type II ROS Generation for Photodynamic Treatment of Drug-Resistant Bacteria

Shanshan Liu et al.

Summary: This article introduces a molecular cationization approach to enhance the generation of reactive oxygen species (ROS) by aggregation-induced emission (AIE) photosensitizers, especially type I ROS, for photodynamic treatment of drug-resistant bacteria.

ACS NANO (2022)

Add to Collection
Article Microbiology

Quorum quenching of Streptococcus mutans via the nano-quercetin-based antimicrobial photodynamic therapy as a potential target for cariogenic biofilm

Maryam Pourhajibagher et al.

Summary: This study evaluated the anti-biofilm potency and anti-metabolic activity of nano-quercetin-mediated antimicrobial photodynamic therapy (aPDT) against Streptococcus mutans. In addition, in silico evaluation showed that aPDT can downregulate the expression of various genes involved in the quorum sensing pathway.

BMC MICROBIOLOGY (2022)

Add to Collection
Article Chemistry, Physical

The relief of hypoxic microenvironment using an O2 self-sufficient fluorinated nanoplatform for enhanced photodynamic eradication of bacterial biofilms

Lingyun Zou et al.

Summary: The study developed oxygen-sufficient fluorinated liposomes that enhanced the photodynamic eradication of bacterial biofilms by relieving the hypoxic microenvironment and promoting ROS generation under laser irradiation. The co-delivered O-2 carrier PFH significantly improved the bactericidal capability of PDT. Lip-Ce6-PFH@O-2 showed better antibiofilm ability than Lip-Ce6, alleviated inflammation symptoms, and accelerated wound healing in a mouse model, providing a new paradigm for enhancing the therapeutic efficacy of PDT for efficient biofilm eradication.

NANO RESEARCH (2022)

Add to Collection
Review Materials Science, Multidisciplinary

Stimuli-responsive nanocarriers for bacterial biofilm treatme

Meng Ding et al.

Summary: Bacterial biofilm infections pose a long-standing threat to human life and health, with traditional antibiotic therapies proving ineffective in eradicating them. Stimuli-responsive nanocarriers have gained attention for their smart drug release properties, with various stimuli such as enzymes, pH levels, and external triggers proving beneficial for biofilm treatment.

RARE METALS (2022)

Add to Collection
Article Multidisciplinary Sciences

Natural transformation allows transfer of SCCmec-mediated methicillin resistance in Staphylococcus aureus biofilms

Mais Maree et al.

Summary: This study demonstrates that natural transformation plays a role in the transfer of SCCmec and possibly other mobile genetic elements in S. aureus biofilms, and biofilm growth conditions enhance the efficiency of natural transformation in S. aureus.

NATURE COMMUNICATIONS (2022)

Add to Collection
Article Engineering, Biomedical

Acid-Responsive Nanoporphyrin Evolution for Near-Infrared Fluorescence-Guided Photo-Ablation of Biofilm

Mengyao Yang et al.

Summary: This study develops an acid-responsive nanoporphyrin for accurate diagnosis and treatment of biofilm infections, avoiding damage to normal tissue and offering a promising alternative to antibiotics.

ADVANCED HEALTHCARE MATERIALS (2022)

Add to Collection
Article Medicine, General & Internal

Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019

Kevin S. Ikuta et al.

Summary: This study provides comprehensive estimates of deaths associated with 33 bacterial pathogens worldwide, highlighting the significant global health burden of bacterial infections. Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae, Klebsiella pneumoniae, and Pseudomonas aeruginosa are the top five deadliest pathogens, and the deadliest infectious syndromes and pathogens vary by location and age.

LANCET (2022)

Add to Collection
Review Microbiology

The biofilm life cycle: expanding the conceptual model of biofilm formation

Karin Sauer et al.

Summary: This review introduces a model of bacterial biofilm formation and points out that the current five-step model fails to capture many aspects of biofilm physiology. The authors propose a more inclusive model that can accommodate various scenarios of biofilm formation.

NATURE REVIEWS MICROBIOLOGY (2022)

Add to Collection
Article Microbiology

Virulence Factors in Colorectal Cancer Metagenomes and Association of Microbial Siderophores with Advanced Stages

Nour El Houda Mathlouthi et al.

Summary: Colorectal cancer is a complex disease, and gut microbiota plays a significant role in its development and progression. The study found that the microbiota in colorectal cancer patients is enriched with virulence factors related to cell adhesion, isochorismatase, and microbial siderophores. Furthermore, advanced stages of colorectal cancer showed increased abundances of proteins associated with antibiotic resistance and biofilm development.

MICROORGANISMS (2022)

Add to Collection
Article Nanoscience & Nanotechnology

Bioactive AIEgens Tailored for Specific and Sensitive Theranostics of Gram-Positive Bacterial Infection

Yunxia Wang et al.

Summary: Diseases caused by bacterial infections pose an increasing threat to human health. This study focuses on the development of antibacterial materials that can specifically recognize and kill Gram-positive bacteria. The researchers designed and prepared a series of positively charged photosensitizers with aggregation-induced emission and reactive oxygen species generation ability. These sensitizers demonstrated sensitive and specific recognition and killing effects on Gram-positive bacteria through electrostatic adsorption and void permeability. The research provides superior material-integrated diagnosis and treatment for diseases caused by Gram-positive bacteria and shows potential for addressing bacterial resistance.

ACS APPLIED MATERIALS & INTERFACES (2022)

Add to Collection
Article Engineering, Environmental

A ?sense-and-treat? hydrogel for rapid diagnose and photothermal therapy of bacterial infection

Xianghong Xie et al.

Summary: This study presents a system integrating sensing and sterilization by incorporating pH indicator and near-infrared nanosheets into hydrogels. The pH indicator allows for easy diagnosis of bacterial infection, followed by photothermal therapy for killing bacteria. Additionally, a colorimetric band-aid hydrogel platform is proposed for real-time monitoring of wound healing process.

CHEMICAL ENGINEERING JOURNAL (2022)

Add to Collection
Article Chemistry, Multidisciplinary

Mitochondria-targeting Type I AIE photosensitizer combined with H2S therapy: Uninterrupted hydroxyl radical generation for enhancing tumor therapy

Tianfu Zhang et al.

Summary: An uninterrupted ROS generator was developed for cancer therapy, which utilizes an H2S donor and a Type I AIE photosensitizer to generate continuous middotOH in tumors. By blocking the H2O2 consumption pathway, continuous middotOH generation was achieved, improving the efficacy of tumor therapy.

NANO TODAY (2022)

Add to Collection
Review Chemistry, Multidisciplinary

Biofilm microenvironment-responsive nanoparticles for the treatment of bacterial infection

Yanling Hu et al.

Summary: Biofilm infectious diseases have become a growing global health issue, and conventional antibiotic therapy is ineffective due to poor biofilm penetration and antibiotic tolerance. The development of biofilm microenvironment-responsive nanoparticles offers a promising strategy for combating biofilm infection.

NANO TODAY (2022)

Add to Collection
Review Chemistry, Multidisciplinary

Biofilms: Formation, Research Models, Potential Targets, and Methods for Prevention and Treatment

Yajuan Su et al.

Summary: This review article discusses the threat of biofilms to human health, explores the mechanisms of biofilm formation and treatment strategies, and summarizes established biofilm models used in research. Furthermore, it discusses potential targets for the development of new strategies to combat biofilms and presents the latest technologies for the prevention and treatment of biofilms. The article concludes by pointing out directions for future studies.

ADVANCED SCIENCE (2022)

Add to Collection
Article Chemistry, Multidisciplinary

A novel furo[3,2-c]pyridine-based AIE photosensitizer for specific imaging and photodynamic ablation of Gram-positive bacteria

Ming-Yu Wu et al.

Summary: An AIE-active furo[2,3-c]pyridine-based photosensitizer, LIQ-TF, was synthesized through Rh-catalyzed tandem reaction. LIQ-TF exhibited near-infrared emission with high quantum yield, and high efficiency in generating O-1(2) and (OH)-O-center dot, which could be used for specific imaging and photodynamic ablation of Gram-positive bacteria in vitro and in vivo, demonstrating great potential for combating multiple drug-resistant bacteria.

CHEMICAL COMMUNICATIONS (2022)

Add to Collection
Article Chemistry, Multidisciplinary

AIE-active luminogens as highly efficient free-radical ROS photogenerator for image-guided photodynamic therapy

Zhenxing Liu et al.

Summary: This study reports on a type I-based aggregation-induced emission (AIE) photosensitizer TCM-CPS with low oxygen dependence, near-infrared emission, and off-on fluorescence. The rational design of TCM-CPS allows for reduced autofluorescence interference in bio-imaging and enhanced generation of reactive oxygen species (ROS) for efficient cancer cell and bacteria killing.

CHEMICAL SCIENCE (2022)

Add to Collection
Article Gastroenterology & Hepatology

Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis

Maximilian Baumgartner et al.

Summary: The study reveals the presence of mucosal biofilms in a subset of patients with IBS and ulcerative colitis, which are associated with disrupted bile acid metabolism and bacterial dysbiosis. This provides new insights into the pathophysiology of IBS and ulcerative colitis.

GASTROENTEROLOGY (2021)

Add to Collection
Review Microbiology

Inhibition of Streptococcus mutans biofilm formation by strategies targeting the metabolism of exopolysaccharides

Yongwang Lin et al.

Summary: This review summarizes plausible strategies targeting Streptococcus mutans biofilms by degrading EPS structure, inhibiting EPS production, and disturbing the EPS metabolism-related gene expression and regulatory systems.

CRITICAL REVIEWS IN MICROBIOLOGY (2021)

Add to Collection
Review Biochemistry & Molecular Biology

The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies

Celia Andres Juan et al.

Summary: Living species are constantly exposed to oxidants, leading to oxidative stress and disease. The induction of oxidative stress is caused by an imbalance between radical species and antioxidant defense systems, which can damage cellular biomolecules.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Novel Strategies to Combat Bacterial Biofilms

Fatemeh Hemmati et al.

Summary: Biofilms are a severe problem in bacterial infection treatment, with new therapeutic approaches needed to address biofilm-related infections. Potential strategies to inhibit bacterial biofilm development include the use of antiadhesion agents, AMPs, and other methods to interfere with different phases of biofilm development.

MOLECULAR BIOTECHNOLOGY (2021)

Add to Collection
Article Chemistry, Multidisciplinary

Fabrics Attached with Highly Efficient Aggregation-Induced Emission Photosensitizer: Toward Self-Antiviral Personal Protective Equipment

Bin Li et al.

Summary: This study introduces a fabric manufacturing method based on a highly efficient aggregation-induced emission photosensitizer (ASCP-TPA) for real-time self-antiviral capabilities. The fabrics show significant photodynamic inactivation effects against a surrogate coronavirus MHV-A59, with >99.999% virions eliminated within 10 minutes under ultralow-power white light irradiation. These self-antiviral fabrics offer reusability, long-term usability, and no toxicity to normal skin, making them a promising solution to global PPE supply shortages.

ACS NANO (2021)

Add to Collection
Article Chemistry, Multidisciplinary

A Membrane-Targeting Photosensitizer with Aggregation-Induced Emission Characteristics for Highly Efficient Photodynamic Combat of Human Coronaviruses

Ming-Yu Wu et al.

Summary: This study reports the efficient inactivation of human coronavirus with photodynamic therapy using photosensitizers with aggregation-induced emission characteristics. The photosensitizer can effectively target and inactivate the virus under light irradiation, providing a new avenue for combating COVID-19 with photodynamic therapy.

SMALL (2021)

Add to Collection
Editorial Material Public, Environmental & Occupational Health

Antimicrobial resistance: a global public health emergency further exacerbated by international travel

Marisa Holubar

JOURNAL OF TRAVEL MEDICINE (2020)

Add to Collection
Article Microbiology

Naringin sensitizes the antibiofilm effect of ciprofloxacin and tetracycline against Pseudomonas aeruginosa biofilm

Pia Dey et al.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2020)

Add to Collection
Review Microbiology

Biofilm dispersion

Kendra P. Rumbaugh et al.

NATURE REVIEWS MICROBIOLOGY (2020)

Add to Collection
Article Chemistry, Physical

Biofilm-Responsive Polymeric Nanoparticles with Self-Adaptive Deep Penetration for In Vivo Photothermal Treatment of Implant Infection

Congyu Wang et al.

CHEMISTRY OF MATERIALS (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Self-Propelled Active Photothermal Nanoswimmer for Deep-Layered Elimination of Biofilm In Vivo

Tingting Cui et al.

NANO LETTERS (2020)

Add to Collection
Article Microbiology

Mycoplasma genitalium Biofilms Contain Poly-GlcNAc and Contribute to Antibiotic Resistance

James M. Daubenspeck et al.

FRONTIERS IN MICROBIOLOGY (2020)

Add to Collection
Review Nanoscience & Nanotechnology

Emerging nanobiomaterials against bacterial infections in postantibiotic era

Dengfeng Hu et al.

VIEW (2020)

Add to Collection
Letter Immunology

Swine methicillin-resistant Staphylococcus aureus carrying toxic-shock syndrome toxin gene in Hong Kong, China

Dulmini Nanayakkara Sapugahawatte et al.

EMERGING MICROBES & INFECTIONS (2020)

Add to Collection
Article Chemistry, Physical

Killing G(+) or G(-) Bacteria? The Important Role of Molecular Charge in AIE-Active Photosensitizers

Xiujuan Shi et al.

SMALL METHODS (2020)

Add to Collection
Article Biophysics

Biofilms and vulvovaginal candidiasis

Carmen Rodriguez-Cerdeira et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

Add to Collection
Review Microbiology

Bacterial quorum sensing in complex and dynamically changing environments

Sampriti Mukherjee et al.

NATURE REVIEWS MICROBIOLOGY (2019)

Add to Collection
Review Chemistry, Multidisciplinary

Nanotechnology-based antimicrobials and delivery systems for biofilm-infection control

Yong Liu et al.

CHEMICAL SOCIETY REVIEWS (2019)

Add to Collection
Article Chemistry, Multidisciplinary

Metal-Organic Framework as a Simple and General Inert Nanocarrier for Photosensitizers to Implement Activatable Photodynamic Therapy

Fang Hu et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

Add to Collection
Review Microbiology

Glycointeractions in bacterial pathogenesis

Jessica Poole et al.

NATURE REVIEWS MICROBIOLOGY (2018)

Add to Collection
Review Multidisciplinary Sciences

Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention

Zohra Khatoon et al.

HELIYON (2018)

Add to Collection
Review Chemistry, Analytical

Quorum sensing: Little talks for an effective bacterial coordination

Nouha Bakaraki Turan et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2017)

Add to Collection
Review Microbiology

Two-Component Signal Transduction Systems of Pathogenic Bacteria As Targets for Antimicrobial Therapy: An Overview

Sandeep Tiwari et al.

FRONTIERS IN MICROBIOLOGY (2017)

Add to Collection
Article Materials Science, Biomaterials

Enhancement of photobactericidal activity of chlorin-e6-cellulose nanocrystals by covalent attachment of polymyxin B

Florent Le Guern et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

Add to Collection
Article Chemistry, Multidisciplinary

An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine

Shengke Li et al.

CHEMICAL COMMUNICATIONS (2017)

Add to Collection
Article Nanoscience & Nanotechnology

Cholesterol-Assisted Bacterial Cell Surface Engineering for Photodynamic Inactivation of Gram-Positive and Gram-Negative Bacteria

Hao-Ran Jia et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Add to Collection
Review Microbiology

Microbial Surface Colonization and Biofilm Development in Marine Environments

Hongyue Dang et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2016)

Add to Collection
Review Biochemical Research Methods

Clinical applications of bacterial glycoproteins

Kelly M. Fulton et al.

EXPERT REVIEW OF PROTEOMICS (2016)

Add to Collection
Review Pharmacology & Pharmacy

Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

Oana Ciofu et al.

ADVANCED DRUG DELIVERY REVIEWS (2015)

Add to Collection
Review Biotechnology & Applied Microbiology

Oxidative Phosphorylation Revisited

Sunil Nath et al.

BIOTECHNOLOGY AND BIOENGINEERING (2015)

Add to Collection
Review Chemistry, Multidisciplinary

Recent Developments in Synthetic Carbohydrate-Based Diagnostics, Vaccines, and Therapeutics

Alberto Fernandez-Tejada et al.

CHEMISTRY-A EUROPEAN JOURNAL (2015)

Add to Collection
Article Microbiology

A Novel Signal Transduction Pathway that Modulates rhl Quorum Sensing and Bacterial Virulence in Pseudomonas aeruginosa

Qiao Cao et al.

PLOS PATHOGENS (2014)

Add to Collection
Review Immunology

Quorum sensing in group A Streptococcus

Juan Cristobal Jimenez et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2014)

Add to Collection
Review Materials Science, Multidisciplinary

Evolving strategies for preventing biofilm on implantable materials

Sarita R. Shah et al.

MATERIALS TODAY (2013)

Add to Collection
Review Biotechnology & Applied Microbiology

Applying insights from biofilm biology to drug development - can a new approach be developed?

Thomas Bjarnsholt et al.

NATURE REVIEWS DRUG DISCOVERY (2013)

Add to Collection
Review Microbiology

Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections

Julian G. Hurdle et al.

NATURE REVIEWS MICROBIOLOGY (2011)

Add to Collection
Review Microbiology

The biofilm matrix

Hans-Curt Flemming et al.

NATURE REVIEWS MICROBIOLOGY (2010)

Add to Collection
Article Biochemistry & Molecular Biology

The Gene Ontology in 2010: extensions and refinements The Gene Ontology Consortium

Tanya Z. Berardini et al.

NUCLEIC ACIDS RESEARCH (2010)

Add to Collection
Article Dentistry, Oral Surgery & Medicine

Periodontitis An archetypical biofilm disease

Christoph Schaudinn et al.

JOURNAL OF THE AMERICAN DENTAL ASSOCIATION (2009)

Add to Collection
Article Hematology

Fibroblast growth factor regulation of neovascularization

Masahiro Murakami et al.

CURRENT OPINION IN HEMATOLOGY (2008)

Add to Collection
Review Dentistry, Oral Surgery & Medicine

Oral biofilms, periodontitis, and pulmonary infections

S. Paju et al.

ORAL DISEASES (2007)

Add to Collection
Article Immunology

Bacterial biofilms in otitis media - Evidence and relevance

Lauren O. Bakaletz

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2007)

Add to Collection
Article Ophthalmology

Prevalence of Staphylococcus epidermidis strains with biofilm-forming ability in isolates from conjunctiva and facial skin

T Suzuki et al.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2005)

Add to Collection
Article Otorhinolaryngology

Is otitis media with effusion a biofilm infection?

N Fergie et al.

CLINICAL OTOLARYNGOLOGY (2004)

Add to Collection
Review Microbiology

Bacterial redox sensors

J Green et al.

NATURE REVIEWS MICROBIOLOGY (2004)

Add to Collection
Article Engineering, Environmental

Photosensitizers neutral red (Type I) and rose bengal (Type II) cause light-dependent toxicity in Chlamydomonas reinhardtii and induce the Gpxh gene via increased singlet oxygen formation

BB Fischer et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2004)

Add to Collection
Review Medicine, General & Internal

Antibiotic resistance of bacteria in biofilms

PS Stewart et al.

LANCET (2001)

Add to Collection
Article Microbiology

Identification of a novel two-component regulatory system that acts in global regulation of virulence factors of Staphylococcus aureus

JM Yarwood et al.

JOURNAL OF BACTERIOLOGY (2001)

Add to Collection
Article Ophthalmology

Acute conjunctivitis associated with biofilm formation on a punctal plug

N Yokoi et al.

JAPANESE JOURNAL OF OPHTHALMOLOGY (2000)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.