4.7 Review

Involvement of CONSTANS-like Proteins in Plant Flowering and Abiotic Stress Response

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

CO interacts with JAZ repressors and bHLH subgroup IIId factors to negatively regulate jasmonate signaling in Arabidopsis seedlings

Xiao Han et al.

Summary: The study reveals the important role of CONSTANS (CO) in mediating physiological responses other than flowering and explains the mechanism of its interaction with jasmonate signaling.

PLANT CELL (2023)

Article Plant Sciences

CONSTANS-LIKE 1a positively regulates salt and drought tolerance in soybean

Chongjing Xu et al.

Summary: The transcription factor GmCOL1a positively regulates salt and drought tolerance in soybean by promoting the accumulation of Delta(1)-pyrroline-5-carboxylate synthetase. GmCOL1a enhances the tolerance of soybean to salt and drought stress by increasing water content, proline content, and reducing oxidative stress. It also promotes the expression of salt tolerance-related genes and reduces Na+/K+ ratio in soybean plants.

PLANT PHYSIOLOGY (2023)

Article Biochemistry & Molecular Biology

Overexpression of two CONSTANS-like 2 (MiCOL2) genes from mango delays flowering and enhances tolerance to abiotic stress in transgenic Arabidopsis

Rong-Zhen Liang et al.

Summary: In this study, the researchers characterized the expression patterns and functions of the CO/COL gene homologs MiCOL2A and MiCOL2B in 'SiJiMi' mango. They found that these genes not only regulate flowering time, but also play a positive role in abiotic stress responses in plants.

PLANT SCIENCE (2023)

Article Biochemistry & Molecular Biology

Chloroplasts prevent precocious flowering through a GOLDEN2-LIKE-B-BOX DOMAIN PROTEIN module

Hendry Susila et al.

Summary: The timing of flowering is controlled by environmental and endogenous signals. Chloroplasts play a role in floral repression and development through retrograde signaling to the nucleus. Mutants defective in chlorophyll biosynthesis and chloroplast development, as well as plants treated with the herbicide norflurazon, flower early. The GLK1/2-BBX14/15/16 module regulates flowering by activating BBX gene expression.

PLANT COMMUNICATIONS (2023)

Article Plant Sciences

CONSTANS interacts with and antagonizes ABF transcription factors during salt stress under long-day conditions

Jiancan Du et al.

Summary: CONSTANS (CO) plays a critical role in regulating flowering in Arabidopsis by integrating photoperiodic and circadian signals. A study shows that CO also responds to salt stress and negatively modulates salt tolerance under long-day conditions. The interaction between CO and the ABF transcription factors, as well as their suppressive effect on salinity-responsive genes, contributes to the regulation of salinity responses in Arabidopsis.

PLANT PHYSIOLOGY (2023)

Article Agricultural Engineering

Expansion of CONSTANS-like genes in sunflower confers putative neofunctionalization in the adaptation to abiotic stresses

Tianzeng Niu et al.

Summary: In this study, 22 putative HaCOL genes were identified and analyzed for their phylogenetic relationships and tissue-specific expression profiles in sunflower. The results suggest that HaCOL genes play important roles in responding to abiotic stresses, with certain genes showing higher sensitivity to stress conditions such as drought and heat. Duplicated genes also contribute to neofunctionalization in response to abiotic stresses.

INDUSTRIAL CROPS AND PRODUCTS (2022)

Article Biochemistry & Molecular Biology

Molecular basis of CONSTANS oligomerization in FLOWERING LOCUS T activation

Xiaolin Zeng et al.

Summary: The transcription factor CONSTANS (CO) forms a head-to-tail oligomeric configuration via its B-boxes to mediate the activation of florigen FLOWERING LOCUS T (FT) in long days. The multimerization of CO is crucial for its functionality.

JOURNAL OF INTEGRATIVE PLANT BIOLOGY (2022)

Article Plant Sciences

BBX17 Interacts with CO and Negatively Regulates Flowering Time in Arabidopsis thaliana

Xiaorui Xu et al.

Summary: BBX17, a member of the B-box (BBX) family, acts as a repressor of floral transition under long-day conditions. It interacts with CONSTANS (CO) and represses its ability to control FT expression, leading to delayed flowering phenotype in plants overexpressing BBX17. Additionally, the degradation of BBX17 is regulated by light and requires COP1 and 26S proteasome, making it a key factor in controlling flowering in Arabidopsis thaliana.

PLANT AND CELL PHYSIOLOGY (2022)

Article Plant Sciences

Isolation and functional analysis of two CONSTANS-like 1 genes from mango

Yi-Hang Guo et al.

Summary: The study reveals the important role of MiCOL1A and MiCOL1B genes in mango for regulating flowering and stress response in plants. Overexpression of these genes resulted in delayed flowering time and enhanced drought tolerance in transgenic Arabidopsis.

PLANT PHYSIOLOGY AND BIOCHEMISTRY (2022)

Review Biology

Rice functional genomics: decades' efforts and roads ahead

Rongzhi Chen et al.

Summary: Rice, as one of the most important crops in the world, has seen significant progress in understanding molecular mechanisms and regulatory networks in various rice traits over the past few decades. Advanced technologies such as new genomics methods, high-throughput phenotyping platforms, precise genome-editing tools, environmental microbiome optimization, and synthetic methods will further enhance our understanding of unresolved molecular biology questions in rice and facilitate their integration into agricultural applications.

SCIENCE CHINA-LIFE SCIENCES (2022)

Article Plant Sciences

Genome-Wide Identification and Expression Profiling of CONSTANS-Like Genes in Pepper (Capsicum annuum): Gaining an Insight to Their Phylogenetic Evolution and Stress-Specific Roles

Zhinan Huang et al.

Summary: This study explored the evolutionary relationship and expression patterns of CONSTANS-like (COL) genes in Capsicum annuum. The study identified 10 COL genes in the pepper genome and found that they can be divided into three groups based on gene structure characteristics. The study also showed significant differences in expression patterns of the COL genes in different tissues. Furthermore, the study found that some COL orthologous genes had different expression patterns and were involved in fruit development in pepper compared to tomato. The findings provide a theoretical basis for understanding the functions of COL genes in pepper and their involvement in growth, development, and responses to abiotic stresses.

FRONTIERS IN PLANT SCIENCE (2022)

Article Plant Sciences

BrABF3 promotes flowering through the direct activation of CONSTANS transcription in pak choi

Changwei Zhang et al.

Summary: This study found that ABA can accelerate the transcription of BrCO in pak choi by directly activating BrABF3, thus promoting flowering.

PLANT JOURNAL (2022)

Article Multidisciplinary Sciences

TaCol-B5 modifies spike architecture and enhances grain yield in wheat

Xiaoyu Zhang et al.

Summary: This study reports the influence of spike architecture on grain yield in wheat and successfully cloned the gene TaCOL-B5 that determines the number of spikelet nodes per spike in common wheat. The overexpression of TaCol-B5 increases the spikelet nodes, tillers, and spikes, thereby enhancing grain yield. The allelic variation in TaCOL-B5 affects protein phosphorylation by TaK4.

SCIENCE (2022)

Article Plant Sciences

GIGANTEA Is a Negative Regulator of Abscisic Acid Transcriptional Responses and Sensitivity in Arabidopsis

Beata Siemiatkowska et al.

Summary: Transcriptional reprogramming prior to morphological and physiological acclimation is crucial in drought stress responses, with the phytohormone abscisic acid (ABA) being the key signal regulating gene expression. GIGANTEA (GI) is identified as a key regulator of ABA-regulated transcriptional and physiological responses, controlling oscillations in ABA signals through DNA binding or function of different classes of transcription factors (TFs). GI plays a role in establishing a phase of reduced ABA sensitivity and related physiological responses by interacting with TFs at target regions.

PLANT AND CELL PHYSIOLOGY (2022)

Article Plant Sciences

Genome-wide identification of the mango CONSTANS (CO) family and functional analysis of two MiCOL9 genes in transgenic Arabidopsis

Yuan Liu et al.

Summary: This study identified 31 COL genes from the mango genome and analyzed their expression patterns and potential functions. The results showed that these COL genes play important roles in the growth, development, and stress responses of mango.

FRONTIERS IN PLANT SCIENCE (2022)

Article Plant Sciences

Zinc-finger protein MdBBX7/MdCOL9, a target of MdMIEL1 E3 ligase, confers drought tolerance in apple

Pengxiang Chen et al.

Summary: The study identified MdBBX7 and MdMIEL1 as important factors influencing the response of apple trees to water deficit, shedding light on the molecular mechanisms behind drought tolerance in apples.

PLANT PHYSIOLOGY (2022)

Article Plant Sciences

Structural determinants for NF-Y subunit organization and NF-Y/DNA association in plants

Antonio Chaves-Sanjuan et al.

Summary: NF-Y transcription factor consists of three subunits, NF-YA, NF-YB, and NF-YC, which dimerize through their histone fold domain (HFD) and trimerize to recognize the CCAAT box sequence. Each NF-Y subunit in plants is encoded by multiple genes, allowing for a variety of heterotrimeric combinations and interactions with other proteins to recognize genomic motifs. The unique organization and DNA-binding properties of plant NF-Y subunits play a crucial role in development, growth, and reproduction, with the flexibility to accommodate a diverse range of partners and genomic motifs.

PLANT JOURNAL (2021)

Article Plant Sciences

PIF3/HY5 module regulates BBX11 to suppress protochlorophyllide levels in dark and promote photomorphogenesis in light

Nikhil Job et al.

Summary: The PIF3/HY5 module antagonistically regulates protochlorophyllide synthesis in the dark, with the B-BOX protein BBX11 acting downstream to modulate gene expression. BBX11 directly influences the greening ability of seedlings exposed to light, while also impacting protochlorophyllide accumulation and photobleaching. The expression of BBX11 is regulated by both PIF3 and HY5, highlighting its importance in balancing plant growth in dark and light conditions.

NEW PHYTOLOGIST (2021)

Article Plant Sciences

Characterization of Mungbean CONSTANS-LIKE Genes and Functional Analysis of CONSTANS-LIKE 2 in the Regulation of Flowering Time in Arabidopsis

Chenyang Liu et al.

Summary: This study identified and characterized 14 VrCOL genes in mungbean, analyzed their structural features and expression patterns. The expression patterns of VrCOL genes varied significantly under long-day and short-day conditions, with VrCOL2 overexpression accelerating flowering in Arabidopsis under short-day conditions.

FRONTIERS IN PLANT SCIENCE (2021)

Article Plant Sciences

ThCOL2 Improves the Salt Stress Tolerance of Tamarix hispida

Xiaojin Lei et al.

Summary: The COL-like transcription factor ThCOL2 in the woody halophyte Tamarix hispida plays a significant role in the response to salt stress, particularly in regulating the expression levels under salt stress and ABA treatment. ThCOL2 overexpression enhances salt tolerance by regulating ROS removal and enzyme activity, indicating its potential as a candidate gene for improving salt tolerance. Further analysis of downstream genes regulated by ThCOL2 will provide insights into the salt tolerance regulatory network.

FRONTIERS IN PLANT SCIENCE (2021)

Article Biochemistry & Molecular Biology

The CRY2-COP1-HY5-BBX7/8 module regulates blue light-dependent cold acclimation in Arabidopsis

Youping Li et al.

Summary: Light and temperature are key environmental factors that regulate plant growth. The study uncovers a mechanism by which CRY2-mediated blue-light signaling enhances freezing tolerance, shedding light on the crosstalk between cold and light signaling pathways in plants. The CRYPTOCHROME2-COP1-HY5-BBX7/8 module plays a crucial role in blue light-dependent cold acclimation.

PLANT CELL (2021)

Article Biochemistry & Molecular Biology

Structural insights into the multivalent binding of the Arabidopsis FLOWERING LOCUS T promoter by the CO-NF-Y master transcription factor complex

Xinchen Lv et al.

Summary: Research shows that CONSTANS (CO) is a master transcription factor in triggering the floral transition in plants and is closely related to the regulation of the FLOWERING LOCUS T (FT) gene. CO binds to NUCLEAR FACTOR-YB/YC and forms a high affinity and specificity for the FT promoter through multivalent binding, regulating the transition of floral period.

PLANT CELL (2021)

Article Biotechnology & Applied Microbiology

BBX11 promotes red light-mediated photomorphogenic development by modulating phyB-PIF4 signaling

Zhaoqing Song et al.

Summary: This study reveals that BBX11 physically interacts with both phyB and PIF4, and negatively regulates PIF4 accumulation and its biochemical activity, consequently affecting the expression of PIF4-controlled genes and promoting photomorphogenesis under prolonged red light.

ABIOTECH (2021)

Article Biotechnology & Applied Microbiology

CmBBX8 accelerates flowering by targeting CmFTL1 directly in summer chrysanthemum

Lijun Wang et al.

PLANT BIOTECHNOLOGY JOURNAL (2020)

Article Plant Sciences

FLOWERING LOCUS T Improves Cucumber Adaptation to Higher Latitudes

Shenhao Wang et al.

PLANT PHYSIOLOGY (2020)

Review Biochemistry & Molecular Biology

B-box proteins: Pivotal players in light-mediated development in plants

Zhaoqing Song et al.

JOURNAL OF INTEGRATIVE PLANT BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Environmental Signal-Dependent Regulation of Flowering Time in Rice

Jae Sung Shim et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

B-box transcription factor 28 regulates flowering by interacting with constans

Yin Liu et al.

SCIENTIFIC REPORTS (2020)

Article Biochemistry & Molecular Biology

A Positive Feedback Loop of BBX11-BBX21-HY5 Promotes Photomorphogenic Development in Arabidopsis

Xianhai Zhao et al.

PLANT COMMUNICATIONS (2020)

Article Plant Sciences

FT Modulates Genome-Wide DNA-Binding of the bZIP Transcription Factor FD

Silvio Collani et al.

PLANT PHYSIOLOGY (2019)

Article Plant Sciences

The Arabidopsis thaliana CONSTANS-LIKE 4 (COL4) - A Modulator of Flowering Time

Yvonne Steinbach

FRONTIERS IN PLANT SCIENCE (2019)

Article Multidisciplinary Sciences

BBX4, a phyB-interacting and modulated regulator, directly interacts with PIF3 to fine tune red light-mediated photomorphogenesis

Yueqin Heng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Multidisciplinary Sciences

Apple B-box factors regulate light-responsive anthocyanin biosynthesis genes

Blue J. Plunkett et al.

SCIENTIFIC REPORTS (2019)

Article Multidisciplinary Sciences

Cryptochrome 2 competes with COP1 substrates to repress COP1 ubiquitin ligase activity during Arabidopsis photomorphogenesis

Jathish Ponnu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Plant Sciences

Molecular Reculation of CBF Sicnalinc in Colc Acclimation

Yiting Shi et al.

TRENDS IN PLANT SCIENCE (2018)

Article Plant Sciences

Molecular basis of flowering under natural long-day conditions in Arabidopsis

Young Hun Song et al.

NATURE PLANTS (2018)

Article Multidisciplinary Sciences

Arabidopsis B-BOX32 interacts with CONSTANS-LIKE3 to regulate flowering

Prateek Tripathi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Biochemistry & Molecular Biology

The DTH8-Hd1 Module Mediates Day-Length-Dependent Regulation of Rice Flowering

Anping Du et al.

MOLECULAR PLANT (2017)

Article Biochemistry & Molecular Biology

CONSTANS Imparts DNA Sequence Specificity to the Histone Fold NF-YB/NF-YC Dimer

Nerina Gnesutta et al.

PLANT CELL (2017)

Article Plant Sciences

The control of flowering time by environmental factors

Lae-Hyeon Cho et al.

PLANT JOURNAL (2017)

Article Multidisciplinary Sciences

The F-box protein FKF1 inhibits dimerization of COP1 in the control of photoperiodic flowering

Byoung-Doo Lee et al.

NATURE COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Structural determinants for NF-Y/DNA interaction at the CCAAT box

Valentina Nardone et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2017)

Review Plant Sciences

The link between flowering time and stress tolerance

Kemal Kazan et al.

JOURNAL OF EXPERIMENTAL BOTANY (2016)

Article Biochemistry & Molecular Biology

CONSTANS-like 9 (COL9) delays the flowering time in Oryza sativa by repressing the Ehd1 pathway

Hao Liu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Review Plant Sciences

Stress-induced flowering: the third category of flowering response

Kiyotoshi Takeno

JOURNAL OF EXPERIMENTAL BOTANY (2016)

Article Plant Sciences

Ghd2, a CONSTANS-like gene, confers drought sensitivity through regulation of senescence in rice

Juhong Liu et al.

JOURNAL OF EXPERIMENTAL BOTANY (2016)

Article Plant Sciences

Molecular characterization of CONSTANS-Like (COL) genes in banana (Musa acuminata L. AAA Group, cv. Grand Nain)

Akhilesh Kumar Chaurasia et al.

PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS (2016)

Article Biochemistry & Molecular Biology

Circadian Clock and Photoperiodic Response in Arabidopsis: From Seasonal Flowering to Redox Homeostasis

Jae Sung Shim et al.

BIOCHEMISTRY (2015)

Article Plant Sciences

Conserved CO-FT regulons contribute to the photoperiod flowering control in soybean

Chengming Fan et al.

BMC PLANT BIOLOGY (2014)

Article Multidisciplinary Sciences

Maternal temperature history activates Flowering Locus T in fruits to control progeny dormancy according to time of year

Min Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Release of SOS2 kinase from sequestration with GIGANTEA determines salt tolerance in Arabidopsis

Woe-Yeon Kim et al.

NATURE COMMUNICATIONS (2013)

Article Biochemistry & Molecular Biology

The E3 Ubiquitin Ligase HOS1 Regulates Arabidopsis Flowering by Mediating CONSTANS Degradation Under Cold Stress

Jae-Hoon Jung et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Multidisciplinary Sciences

The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth

Dmitri A. Nusinow et al.

NATURE (2011)

Article Multidisciplinary Sciences

Activation of the plasma membrane Na/H antiporter Salt-Overly-Sensitive 1 (SOS1) by phosphorylation of an auto-inhibitory C-terminal domain

Francisco J. Quintero et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

GIGANTEA directly activates Flowering Locus T in Arabidopsis thaliana

Mariko Sawa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Plant Sciences

Arabidopsis circadian clock and photoperiodism: time to think about location

Takato Imaizumi

CURRENT OPINION IN PLANT BIOLOGY (2010)

Review Plant Sciences

Regulation and function of SOC1, a flowering pathway integrator

Jungeun Lee et al.

JOURNAL OF EXPERIMENTAL BOTANY (2010)

Article Agronomy

Association of a CONSTANS-LIKE gene to flowering and height in autotetraploid alfalfa

Doris Herrmann et al.

THEORETICAL AND APPLIED GENETICS (2010)

Review Plant Sciences

Plant responses to photoperiod

Stephen D. Jackson

NEW PHYTOLOGIST (2009)

Letter Biochemistry & Molecular Biology

The Arabidopsis B-Box Zinc Finger Family

Rajnish Khanna et al.

PLANT CELL (2009)

Review Plant Sciences

Leaf-produced floral signals

Jan A. D. Zeevaart

CURRENT OPINION IN PLANT BIOLOGY (2008)

Article Developmental Biology

Hd3a and RFT1 are essential for flowering in rice

Reina Komiya et al.

DEVELOPMENT (2008)

Article Biochemistry & Molecular Biology

COP1 and ELF3 Control Circadian Function and Photoperiodic Flowering by Regulating GI Stability

Jae-Woong Yu et al.

MOLECULAR CELL (2008)

Article Multidisciplinary Sciences

FT protein movement contributes to long-distance signaling in floral induction of Arabidopsis

Laurent Corbesier et al.

SCIENCE (2007)

Article Multidisciplinary Sciences

Hd3a protein is a mobile flowering signal in rice

Shojiro Tamaki et al.

SCIENCE (2007)

Review Biochemistry & Molecular Biology

Classical nuclear localization signals:: Definition, function, and interaction with importin α

Allison Lange et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Florigen coming of age after 70 years

Jan A. D. Zeevaart

PLANT CELL (2006)

Article Biochemistry & Molecular Biology

Arabidopsis CONSTANS-LIKE3 is a positive regulator of red light signaling and root growth

S Datta et al.

PLANT CELL (2006)

Article Biochemistry & Molecular Biology

Distinct roles of GIGANTEA in promoting flowering and regulating circadian rhythms in Arabidopsis

T Mizoguchi et al.

PLANT CELL (2005)

Review Biochemistry & Molecular Biology

It's time to flower: the genetic control of flowering time

J Putterill et al.

BIOESSAYS (2004)

Article Multidisciplinary Sciences

Photoreceptor regulation of CONSTANS protein in photoperiodic flowering

F Valverde et al.

SCIENCE (2004)

Review Plant Sciences

Regulation of ion homeostasis under salt stress

JK Zhu

CURRENT OPINION IN PLANT BIOLOGY (2003)

Article Plant Sciences

The evolution of CONSTANS-like gene families in barley, rice, and Arabidopsis

S Griffiths et al.

PLANT PHYSIOLOGY (2003)

Article Multidisciplinary Sciences

CONSTANS mediates between the circadian clock and the control of flowering in Arabidopsis

P Suárez-López et al.

NATURE (2001)