☆ 4.7 Article

Nanomaterial surface modification toolkit: Principles, components, recipes, and applications

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2023)

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

Rui Liu et al.

Summary: Decades have passed since the approval of the first nanoparticles-based medicine for human cancer treatment, and research and development in nanoparticles for drug delivery have been continuing. Today, there have been significant advancements in nanoparticles, including liposomes, solid lipid nanoparticles, inorganic nanoparticles, micelles, nanovaccines, and nano-antibodies. These nanoparticles have shown great potential in the treatment and diagnosis of challenging diseases such as cancer and neurodegenerative diseases, making them promising drug carriers and therapeutic agents in the future.

CHINESE CHEMICAL LETTERS (2023)

Add to Collection
Article Polymer Science

Polymer-based biomaterials for pharmaceutical and biomedical applications: A focus on topical drug administration

Patricia C. Pires et al.

Summary: The increasing emergence of skin diseases and the difficulty in treating damaged skin using conventional therapies have called for the development of novel drug delivery systems utilizing natural polymers. These natural polymers offer advantages such as biocompatibility, biodegradability, economic feasibility, and inherent bioactive properties. This review examines the latest drug delivery system technologies using natural polymers and discusses their in vitro, ex vivo, and in vivo experiments. Additionally, it highlights the therapeutic capabilities of biopolymer-based nanoparticles for various skin conditions.

EUROPEAN POLYMER JOURNAL (2023)

Add to Collection
Article Chemistry, Inorganic & Nuclear

Synthesis and characterization of magnetic nanoparticles-grafted-hyaluronic acid/β-cyclodextrin as a novel pH-sensetive nanocarrier for targeted delivery of doxorubicin

Hafez Khodayari et al.

Summary: pH-sensitive magnetic nanocarrier was developed for doxorubicin delivery by grafting hyaluronic acid/beta-cyclodextrin onto Fe3O4 magnetic nanoparticles. The nanocarrier demonstrated strong pH-dependent release behavior, with higher drug release at pH 5.6 compared to pH 7.4. The release mechanism was determined to be controlled by Fickian diffusion kinetic. The surface modification of the magnetic nanoparticles greatly influenced drug sorption and was more compatible with Langmuir isotherm and pseudo-second-order kinetic models. Thermodynamic parameters indicated that the doxorubicin adsorption was endothermic and spontaneous, suggesting physiochemical sorption. These findings highlight the potential of pH-sensitive nanocarriers for drug delivery.

INORGANIC CHEMISTRY COMMUNICATIONS (2023)

Add to Collection
Article Biochemistry & Molecular Biology

pH-responsive magnetic Fe3O4/carboxymethyl chitosan/aminated lignosulfonate nanoparticles with uniform size for targeted drug loading

Qian Liu et al.

Summary: A magnetic delivery system for targeted drug was developed using aminated lignosulfonate (ALS) and carboxymethyl chitosan (CMCS) to fabricate nano Fe3O4 with pH responsiveness. The system successfully loaded doxorubicin hydrochloride (DOX) and demonstrated controlled release of the drug. The particle size ranged from 79.9-169.9 nm under optimized conditions and exhibited excellent pH responsiveness. The drug-loaded particles showed significant growth inhibition on cancer cells.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

Add to Collection
Review Chemistry, Multidisciplinary

Polysaccharide-based nanocarriers for efficient transvascular drug delivery

Min Zhang et al.

Summary: Polysaccharide-based nanocarriers (PBNs) have gained significant attention due to their biocompatibility, cost-effectiveness, availability, and versatility in loading anticancer agents. However, the heterogeneous tumor structures compromise the enhanced permeability and retention (EPR) effect, hindering efficient drug delivery. Overcoming the biological barriers for extravasation from tumor vessels is crucial for optimizing PBNs. Various strategies, including nanocarrier property regulation and tumor structure remodeling, have been developed to enhance the EPR effect. This review summarizes recent advances in the design of PBNs with enhanced transvascular transport and discusses the challenges in understanding the transendothelial mechanism of PBNs and their interactions with other drug delivery steps.

JOURNAL OF CONTROLLED RELEASE (2023)

Add to Collection
Article Pharmacology & Pharmacy

Cladosporium protease/doxorubicin decorated Fe3O4@SiO2 nanocomposite: An efficient nanoparticle for drug delivery and combating breast cancer

Leila Vahabi et al.

Summary: Fe3O4/SiO2 nanocomposite was synthesized and decorated with an extracellular Cladosporium protease, doxorubicin, plus C. protease/DOX molecules. The C. Protease was purified using the mAzo method and its molecular weight was determined as 70 kDa by SDS-PAGE. The nanocomposite was characterized using various techniques. The cytotoxic effect of the decorated nanocomposites on the MCF-7 cancer cell line was studied, showing a 7.5% cell viability.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

Add to Collection
Article Engineering, Environmental

A single thiolated-phage displayed nanobody-based biosensor for label-free detection of foodborne pathogen

Peng Wang et al.

Summary: This study presents a label-free immunostaining strategy based on bacteriophage-displayed nanobody for the detection of Vibrio parahaemolyticus. The developed assay allows simple and sensitive detection of the pathogen within a short period of time, with high specificity and no cross-reactivity towards other bacterial species.

JOURNAL OF HAZARDOUS MATERIALS (2023)

Add to Collection
Article Chemistry, Physical

Amplified EQCM-D detection of extracellular vesicles using 2D gold nanostructured arrays fabricated by block copolymer self-assembly

Jugal Suthar et al.

Summary: Extracellular vesicles (EVs) are released from various cell types and contain biomolecular content for health and disease identification. However, the heterogeneity of EVs and complexity of biofluids pose challenges to current analytical approaches. This study explores nanostructuring the sensor electrode surface to enhance detection capabilities and achieves significant improvement.

NANOSCALE HORIZONS (2023)

Add to Collection
Review Pharmacology & Pharmacy

Biomaterials releasing drug responsively to promote wound healing via regulation of pathological microenvironment

Haisheng Li et al.

Summary: This article discusses recent advances in stimuli-responsive biomaterials for regulating local microenvironments during wound healing. It emphasizes on the design and application of different biomaterials that respond to wound biological/biochemical microenvironments (ROS, pH, enzymes, glucose, and glutathione), physical microenvironments (mechanical force, temperature, light, ultrasound, magnetic, and electric field), and combination modes. Moreover, several novel promising drug carriers (microbiota, metal-organic frameworks, and microneedles) are also discussed.

ADVANCED DRUG DELIVERY REVIEWS (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Functionalisation of Graphene Sensor Surfaces for the Specific Detection of Biomarkers

Laura von Lueders et al.

Summary: We present a controllable and specific functionalisation approach for graphene field-effect transistors (GFETs) in order to detect small physiologically active molecules. The key step involves the noncovalent functionalisation of graphene with perylene bisimide (PBI) molecules directly on the growth substrate. This method allows for the homogeneous self-assembly of PBI molecules on graphene, followed by the immobilization of antibodies. The functionalised GFET devices showed excellent performance in terms of atomic force microscopy, Raman spectroscopy, and electrical measurements compared to conventional functionalisation methods. Specific sensing of small molecules such as methamphetamine and cortisol was achieved by monitoring the electrical changes of the functionalised GFET devices. The sensors were able to detect methamphetamine down to a concentration of 300 ng ml(-1).

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2023)

Add to Collection
Article Engineering, Biomedical

An injectable PEG-like conjugate forms a subcutaneous depot and enables sustained delivery of a peptide drug

Imran Ozer et al.

Summary: In order to solve the problem of the short half-life of biologics, researchers developed an injectable PEG-like conjugate that forms a subcutaneous depot, providing sustained delivery of the drugs. This conjugate showed better pharmacokinetic and pharmacodynamic properties compared to PEG conjugates and branched PEG, and it also remained effective and safe for long-term management of type 2 diabetes without causing an immune response.

BIOMATERIALS (2023)

Add to Collection
Article Biophysics

Development of magnetic poly(L-lactic Acid) nanofibrous microspheres for transporting and delivering targeted cells

Bo Li et al.

Summary: In order to avoid infection and risks associated with large open-surgery incisions, the study focuses on injectable microcarrier-loaded cells for targeted therapy and tissue regeneration. The study successfully fabricates cell carriers that resemble planetary-satellite structures and can freely move under the influence of a magnetic field. In vitro and in vivo experiments demonstrate the biocompatibility and drug-loading capability of the carriers, which provide a versatile and promising platform for cell-based therapy in tissue engineering and regenerative medicine.

COLLOIDS AND SURFACES B-BIOINTERFACES (2023)

Add to Collection
Article Biology

Comparative study of the efficiency of silicon carbide, boron nitride and carbon nanotube to deliver cancerous drug, azacitidine: A DFT study

Nabajyoti Baildya et al.

Summary: In this study, we compared the efficiency of three different nanotubes (carbon nanotube, boron nitride nanotube, and silicon carbide nanotube) in delivering the cancer drug Azacitidine (AZD). Parameters such as adsorption energy, electrostatic potential map, and reduced density gradient were analyzed to understand the encapsulation process of AZD in these nanotubes. The results showed that BNNT and SiCNT had a higher adsorption energy and stronger binding affinity with AZD compared to CNT. Thermodynamic parameters also revealed that the encapsulation process was spontaneous and exothermic, especially with BNNT and SiCNT. Molecular dynamics simulation supported the encapsulation process of AZD in the nanotubes at room temperature. These findings suggest the potential of these nanotubes as drug delivery systems in nanomedicine.

COMPUTERS IN BIOLOGY AND MEDICINE (2023)

Add to Collection
Article Biochemistry & Molecular Biology

Magnetic nanoparticle embedded chitosan-based polymeric network for the hydrophobic drug delivery of paclitaxel

V. Manjusha et al.

Summary: Safe delivery of hydrophobic drugs to the tumor site is a challenging task for the scientific community. In this study, iron oxide nanoparticles coated chitosan with [2-(methacryloyloxy) ethyl] trimethyl ammonium chloride (METAC) (CS-IONPs-METAC-PTX) were developed as a drug carrier for hydrophobic drug delivery. The drug carrier exhibited excellent therapeutic efficacy and selectivity when tested in cell lines, demonstrating its potential for PTX delivery.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Co-delivery of microRNA-150 and quercetin by lipid nanoparticles (LNPs) for the targeted treatment of age-related macular degeneration (AMD)

Wei Li et al.

Summary: Age-related macular degeneration (AMD) is a disease that causes severe vision loss in middle-aged and elderly patients due to choroidal neovascularization (CNV). Current treatments for CNV are ineffective and can have adverse effects. This study developed solid lipid nanoparticles modified with an Asp-Gly-Arg peptide to target endothelial cells during abnormal angiogenesis. These nanoparticles successfully co-delivered microRNA-150 (mR150) and the antiangiogenic drug quercetin, inhibiting CNV without retinal toxicity in a mouse model.

JOURNAL OF CONTROLLED RELEASE (2023)

Add to Collection
Review Pharmacology & Pharmacy

Mesoporous silica nanoparticles: Synthesis and multifaceted functionalization for controlled drug delivery

Jayesh Gupta et al.

Summary: Inorganic mesoporous silica nanoparticles (MSN) have been extensively studied as porous materials for drug delivery due to their easy synthesis methods, tunable pore size, biocompatibility, high loading efficiency, and surface functionalization properties. This review discusses various synthesis approaches and functionalization strategies of MSN for active and passive targeting, including controlled drug delivery with stimuli-sensitive gatekeepers. Additionally, the review explores stimuli-responsive drug delivery approaches targeting pH, redox, enzyme, temperature, light, etc. MSN-based nanoparticles have also been used to achieve enhanced on-demand release and reduce non-specific drug leakage through dual and triple stimuli. The versatility of MSNs makes them promising drug delivery vectors.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

Add to Collection
Review Pharmacology & Pharmacy

Metal phenolic networks (MPNs)-based pH-sensitive stimulus responsive nanosystems for drug delivery in tumor microenvironment

Arbab Ali et al.

Summary: The tumor microenvironment is a complex system in which conventional drug delivery strategies have limitations. The development of nano-based drug delivery has provided solutions by offering controlled release in this environment. This review focuses on the use of metal phenolic networks as pH-sensitive drug carriers in the tumor microenvironment, providing insights and exploring potential applications.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

Add to Collection
Review Pharmacology & Pharmacy

Recent advancements in polymer matrix nanocomposites for bone tissue engineering applications

Suresh Sagadevan et al.

Summary: In recent years, polymer-based nanocomposites have been extensively studied and utilized in tissue engineering for bone regeneration. These biodegradable nanocomposites have shown advantages in bone tissue cultivation and production. While some polymeric materials used in bone tissue engineering are biodegradable and bioactive, they often lack the required strength. Conversely, metallic implants are mechanically strong but pose risks of infection and secondary surgery. Polymer nanocomposites, on the other hand, possess bioinertness, low chemical reactivity, and the capability to mimic bone characteristics for orthopedic applications, offering potential solutions for bone abnormalities.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Revisiting Alkoxysilane Assembly on Silica Surfaces: Grafting versus Homo-Condensation in Solution

Yannick Millot et al.

Summary: Silica surface functionalization is commonly achieved by condensation of functional silanes on silanols. However, the presence of APTES on silica and silicate materials is mainly due to homo-condensation rather than heterocondensation with silanol groups. The accurate estimation of homo-condensation vs grafting can be determined by analyzing the signal related to silicon atoms from silanes and silica.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2023)

Add to Collection
Review Materials Science, Multidisciplinary

Nanobiomaterial vectors for improving gene editing and gene therapy

Shao Wei Hu et al.

Summary: With the advancement of genome editing techniques, gene therapy is increasingly being used for the treatment of various human diseases. Nanomaterials have shown great potential in improving the efficiency and safety of gene editing in gene therapy. This review introduces three gene editing tools, with a particular focus on the development and optimization of the CRISPR system. It also discusses the recent application of nanobiomaterials in gene therapy, along with the prospects and remaining challenges. Lastly, future directions for gene editing tools, nanobiomaterial vectors, and gene therapy are presented.

MATERIALS TODAY (2023)

Add to Collection
Review Pharmacology & Pharmacy

Lipid nanomaterials-based RNA therapy and cancer treatment

Xingcai Zhang et al.

Summary: This article summarizes the most important advances in RNA delivery and nanomedicine, introducing lipid nanoparticle-based RNA therapeutics and their impact on drug development. It describes the fundamental properties of key RNA members and recent advances in nanoparticles for targeted RNA delivery, with a focus on lipid nanoparticles. The review also presents recent advances in biomedical therapy using RNA drug delivery and state-of-the-art RNA application platforms, including the treatment of different types of cancer.

ACTA PHARMACEUTICA SINICA B (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Enzymatic Catalysis in Size and Volume Dual-Confined Space of Integrated Nanochannel-Electrodes Chip for Enhanced Impedance Detection of Salmonella

Yue Li et al.

Summary: In this study, a novel and highly sensitive bacteria detection method was developed based on the dual-confinement effects of size and volume in a nanochannel-electrodes chip. The size confinement in the nanochannels promoted enzyme catalysis efficiency, while the volume confinement in the micro-droplet-based electrochemical cell enriched ions by restricting diffusion. This work contributes to the understanding of nanoconfined processes and provides a new signal transduction technique for trace analysis.

SMALL (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Cyclodextrin modified with different groups to enhance the drug delivery efficiency of gold nanoparticles to treat cancer

Cao-Hien Nguyen et al.

Summary: The aim of this research is to investigate the influence of different functional groups of b-cyclodextrin (CD) in functionalizing gold nanoparticles for drug delivery. TMACD was found to be the most effective in loading 5-FU and protected the drug with low release percentage. The nanocomposite AuNPs/TMACD exhibited the highest efficacy in suppressing the growth of breast cancer cells.

ARABIAN JOURNAL OF CHEMISTRY (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Controlling the Binding Efficiency of Surface Confined Antibodies through the Design of Mixed Self-Assembled Monolayers

Lucia Sarcina et al.

Summary: A variety of electronic and optoelectronic devices have been developed recently for biosensing applications, with a focus on a detecting interface that incorporates biorecognition elements anchored by self-assembled monolayers (SAMs) on a gold surface. This study investigates the effect of different SAM structures on the packing efficiency of antibodies and the analytical performance of sensors by performing surface plasmon resonance (SPR) characterization of anti-p24 anchored on these SAMs. The results show that the choice of SAM significantly affects the binding efficiency of antibodies against the HIV p24 protein, and density functional theory calculations provide a molecular understanding of these observations.

ADVANCED MATERIALS INTERFACES (2023)

Add to Collection
Review Chemistry, Multidisciplinary

A Nanotechnology-Based Approach to Biosensor Application in Current Diabetes Management Practices

Ambreen Shoaib et al.

Summary: Diabetes mellitus is a serious condition that can lead to various health problems. Early detection is crucial, and biosensors have proven to be effective in diagnosing and monitoring diabetes. The incorporation of nanotechnology has further enhanced the performance and sensitivity of these biosensors, allowing for disease detection and therapy tracking. This article focuses on the applications of biosensors in diabetes management, including glucose sensors and printed biosensors. It also discusses the advances and challenges of nanotechnology-based biosensors for medical use.

NANOMATERIALS (2023)

Add to Collection
Article Materials Science, Multidisciplinary

Influence of chemical and bio-surfactants on physiochemical properties in mesoporous silica nanoparticles synthesis

Raju Kumar Sharma et al.

Summary: This study investigated the synthesis of mesoporous silica nanoparticles using four different surfactants. The outcomes showed that Tween-80 and biosurfactant produced interesting results compared to CTAB and SDS-mediated silica nanoparticles.

JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Signal Amplification in Electrochemical DNA Biosensors Using Target-Capturing DNA Origami Tiles

Paul Williamson et al.

Summary: Electrochemical DNA (e-DNA) biosensors are effective tools for disease monitoring, as they can translate hybridization events into recordable electrical signals. In this study, a strategy for amplifying electrochemical signals associated with DNA hybridization was reported using DNA origami method, leading to an improved sensor limit of detection and high strand selectivity. This approach could address the sensitivity requirements for low-cost point-of-care devices.

ACS SENSORS (2023)

Add to Collection
Article Nanoscience & Nanotechnology

Fluorometric and Colorimetric Hybrid Carbon-Dot Nanosensors for Dual Monitoring of Urea

Mohamed R. Elmasry et al.

Summary: In this study, a dual-signal nanosensor was designed for rapid and accurate urea detection using fluorescent carbon dot nanosensors and plasmonic silver nanoparticles. The sensor showed low detection limits and reliable performance in real urine samples.

ACS APPLIED NANO MATERIALS (2023)

Add to Collection
Review Chemistry, Multidisciplinary

Theranostic polymeric nanoparticles as a new approach in cancer therapy and diagnosis: a review

S. M. Hosseini et al.

Summary: Theranostic is a revolutionary topic in cancer treatment, combining therapeutic and diagnostic. Nanoscale carriers have great potential as platforms in theranostic applications.

MATERIALS TODAY CHEMISTRY (2023)

Add to Collection
Article Chemistry, Applied

Synthesis of fluorescent probe based on molecularly imprinted polymers on nitrogen-doped carbon dots for determination of tobramycin in milk

Yunyan Ren et al.

Summary: In this study, nitrogen-doped carbon dot-based molecularly imprinted polymers (N-CDs@MIPs) were successfully prepared for the trace analysis of tobramycin in milk. The probe showed high sensitivity and selectivity compared to other techniques and can be an alternative method for the detection of tobramycin.

FOOD CHEMISTRY (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Drug content on anticancer efficacy of self-assembling ketal-linked dextran-paclitaxel conjugates

Tiantian Guo et al.

Summary: In this study, we synthesized four dextran-paclitaxel (PTX) conjugates with different drug contents and used them to construct self-assembled nanoparticles. We investigated how PTX content influenced the performance and antitumor efficacy of the nanoparticles. The results showed that nanoparticles with lower PTX content exhibited faster drug release, increased tumor accumulation, and enhanced antitumor efficacy.

JOURNAL OF CONTROLLED RELEASE (2023)

Add to Collection
Article Pharmacology & Pharmacy

Depot unilamellar liposomes to sustain transscleral drug Co-delivery for ophthalmic infection therapy

Jing Su et al.

Summary: Periocular routes have great potential for the treatment of chronic eye diseases by exploiting the scleral structure. In this study, phosphatidylcholine-based liposomes (LIP-DM) were developed to deliver water-soluble steroid dexamethasone and antibiotics moxifloxacin through the sclera. The results demonstrated that LIP-DM exhibited differential release of the two drugs, with fast release of moxifloxacin and slow release of dexamethasone, leading to increased transscleral contact time and enhanced antibacterial and anti-inflammatory effects.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

Add to Collection
Review Pharmacology & Pharmacy

Harnessing chitosan-adorned liposomes for enhanced drug delivery in cancer

Mohammad Arshad Javed Shaikh et al.

Summary: Cancer is a complex disease influenced by genetics, environment, and lifestyle choices. The management of cancer relies on chemotherapy, surgery, and radiation therapy, but combination therapies are also utilized. Despite low success rates, chemotherapy remains the standard treatment. Drug delivery systems, such as chitosan liposomes, offer advantages in overcoming drug penetration and resistance challenges. This article explores the use of chitosan liposomes for cancer treatment through various routes, including immunotherapy and targeted therapy.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

Add to Collection
Article

Nanoparticle-based drug delivery across the blood-brain barrier for treating malignant brain glioma

Vishwanath Kurawattimath et al.

OpenNano (2023)

Add to Collection
Article Chemistry, Physical

Ionizable Amino Lipids Distribution and Effects on DSPC/Cholesterol Membranes: Implications for Lipid Nanoparticle Structure

Sepehr Dehghani-Ghahnaviyeh et al.

Summary: Lipid nanoparticles containing ionizable aminolipids play a crucial role in delivering nucleic-acid-based therapeutics. This study investigated the distribution and effects of Lipid-5, an ionizable aminolipid, on lipid bilayers using molecular dynamics simulations. The results showed that high concentrations of ionizable aminolipids led to the formation of a disordered aggregate of neutral aminolipids in the membrane interior, preferentially incorporating cholesterol. These findings provide guidance for optimizing the function of lipid nanoparticles.

JOURNAL OF PHYSICAL CHEMISTRY B (2023)

Add to Collection
Article Chemistry, Analytical

Magnetic graphene oxide nanocomposite as dual-mode genosensor for ultrasensitive detection of oncogenic microRNA

Pinpinut Kabinsing et al.

Summary: This study designed multifunctional nanosheets for the capture, detection, and quantification of miRNA 183-5p from prostate cancer cells using a disposable printed electrode and a portable potentiostat. Magnetic reduced graphene oxide (MrGO) was used as the starting nanocomposite to analyze miRNA. Two strategies were used for miRNA detection, and the intercalator method showed better performance. The detection limits of miRNA in human serum and urine were 3.73 and 0.86 aM, with a linear range from 0.1 nM to over 1 aM. The incorporation of MrGO, screen-printed carbon electrodes, and portable potentiostat simplified the analysis process and reduced time and cost.

MICROCHEMICAL JOURNAL (2023)

Add to Collection
Article Chemistry, Analytical

Highly sensitive and selective fluorescence sensor based on zirconia nanotube array films for Cu2+detection

Dongxin Liu et al.

Summary: ZrO2 nanotube array films (ZNA) were prepared through anodisation method and modified with gamma-aminopropyltriethoxysilane (APTES) to obtain amino-functionalized ZNA (ZNA-NH2). Cu2+ ion detection was achieved by immobilizing Cu2+ ions and RB on ZNA and ZNA-NH2, and measuring the change in fluorescence intensity of RB. The effects of APTES and RB concentrations on the detection performances were studied, and ZNA-NH2 exhibited significantly better fluorescence detection performances compared to ZNA. The optimal detection performances for Cu2+ ions were obtained with an RB concentration of 10 mg/L and an APTES concentration of 0.4 M, with a minimum detection limit of 0.68 nM (S/N = 3) and a linear range from 1 x 10-3 to 3 x 102 μM under the optimal experimental conditions. The carriers could be regenerated and reused after being soaked in acetic acid solution. This work can be applied to the detection of Cu2+ ions in real seawater.

SENSORS AND ACTUATORS B-CHEMICAL (2023)

Add to Collection
Article Engineering, Chemical

Pristine Multi-walled carbon nanotubes for a rapid and efficient plasmid DNA clarification

P. Ferreira et al.

Summary: Therapeutic approaches based on nucleic acids have gained attention, but require effective manufacturing strategies and precise quality control. This study describes a simple and efficient method using carbon nanotubes to selectively capture RNA and other impurities, resulting in the isolation and clarification of plasmid DNA (pDNA) from complex samples.

SEPARATION AND PURIFICATION TECHNOLOGY (2023)

Add to Collection
Article Chemistry, Applied

Diselenide-triggered hydroxyethyl starch conjugate nanoparticles with cascade drug release properties for potentiating chemo-photodynamic therapy

Ronghua Tan et al.

Summary: A novel HES-SeSe-DOX conjugate was synthesized and self-assembled into HES-SeSe-DOX/Ce6 nanoparticles for chemo-photodynamic anti-tumor therapy. These nanoparticles disintegrated through cleavage or oxidation of diselenide-bridged linkages, resulting in cascade drug release. In vitro and in vivo studies demonstrated the enhanced cytotoxicity against tumor cells and tumor growth inhibition with good safety, suggesting the potential clinical use of HES-SeSe-DOX/Ce6 nanoparticles in chemo-photodynamic tumor therapy.

CARBOHYDRATE POLYMERS (2023)

Add to Collection
Article Chemistry, Physical

Synthesis of core-shell fluorescent silica nanoparticles with opposite surface charges for transport studies of nanofluids in porous media

A. Pazini et al.

Summary: In this study, core-shell silica-based fluorescent SiNPs were used as tracers to investigate the transport of nanofluids containing surfactants in porous media. The SiNPs with aminopropyl surface groups showed the best stability and lowest adsorption during the transport process. These fluorescent NPs have the potential to be sensitive tracers for transport and adsorption studies in nanofluids containing surfactants.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2023)

Add to Collection
Article Biophysics

Biomedical applications of biodegradable polycaprolactone-functionalized magnetic iron oxides nanoparticles and their polymer nanocomposites

Oluwafemi S. Obisesan et al.

Summary: Magnetic nanoparticles (MNPs) have become a focus of attention in the past decade due to their unique properties, making them suitable for drug delivery and various biomedical applications when combined with biodegradable polymers. This review discusses the synthesis of polycaprolactones (PCL), methods of synthesizing magnetic iron oxide nanoparticles, and the synthesis of PCL-based composites. It comprehensively reviews the application of these composites in drug delivery, cancer treatment, wound healing, hyperthermia, bone tissue engineering, and other biomedical applications.

COLLOIDS AND SURFACES B-BIOINTERFACES (2023)

Add to Collection
Article Chemistry, Multidisciplinary

CeO2@NH2 functionalized electrodes for the rapid detection of SARS-CoV-2 spike receptor binding domain

Ayu Triastuti et al.

Summary: A detection method based on an electrochemical aptasensor has been developed for detecting the SARS-CoV-2 Spike Receptor Binding Domain (spike RBD). The aptasensor showed high accuracy and a detection limit of 0.017 ng mL(-1). It has potential as a rapid test method for clinical samples.

RSC ADVANCES (2023)

Add to Collection
Article Materials Science, Multidisciplinary

Functionalization of cellulose nanofibrils to develop novel ROS-sensitive biomaterials

Carlos Palo-Nieto et al.

Summary: Wood derived cellulose nanofibrils (CNFs) have been explored as interesting materials for biomedicine. This study proposed the functionalization of CNFs with a ROS-sensitive oligopeptide to develop a novel CNF-based material for medical conditions associated with high levels of ROS. Various approaches were used to optimize the reaction conditions and characterize the properties of the CNF materials. The results showed that the functionalized CNF hydrogels promoted cell survival in an oxidative environment, indicating their potential for use in chronic wound therapies.

MATERIALS ADVANCES (2023)

Add to Collection
Article Engineering, Biomedical

Our contributions to applications of mesoporous silica nanoparticles

Maria Vallet-Regi

Summary: This article reports our contributions to mesoporous silica materials in biomedicine, demonstrating their potential in drug delivery with high loading capacity and stimuli-responsive features. The research findings suggest that mesoporous silica nanoparticles have promising applications in drug delivery.

ACTA BIOMATERIALIA (2022)

Add to Collection
Article Chemistry, Analytical

Poly-L-Lysine-Modified Graphene Field-Effect Transistor Biosensors for Ultrasensitive Breast Cancer miRNAs and SARS-CoV-2 RNA Detection

Jianwei Gao et al.

Summary: This article introduces a method for detecting breast cancer miRNA and viral RNA using a poly-L-lysine functionalized graphene field-effect transistor (PGFET) biosensor. The experimental results show that the PGFET biosensor has ultra-high sensitivity and rapid detection speed, making it suitable for rapid cancer diagnosis and virus screening.

ANALYTICAL CHEMISTRY (2022)

Add to Collection
Article Biophysics

Gold nanoparticle based plasmonic sensing for the detection of SARS-CoV-2 nucleocapsid proteins

Kamyar Behrouzi et al.

Summary: This article introduces a virus detection scheme based on LSPR principle with gold nanoparticles aggregation, which can provide observable results by the naked eye in 5 minutes with a LOD of 150 ng/ml for N proteins. A comprehensive numerical model is developed to identify key parameters, and the linear relationship between a defined parameter and N protein concentrations is found to be useful for quantitative detection of the virus.

BIOSENSORS & BIOELECTRONICS (2022)

Add to Collection
Review Chemistry, Multidisciplinary

Click and Bioorthogonal Chemistry: The Future of Active Targeting of Nanoparticles for Nanomedicines?

Ludivine Taiariol et al.

Summary: Click and bioorthogonal reactions are high-performance chemical reactions that have gained considerable attention in the biomedical field for the engineering of nanomedicines. This review compiles articles from 2014 to the present to highlight the application and main strategies of click chemistry and nanoparticles in biomedical applications.

CHEMICAL REVIEWS (2022)

Add to Collection
Article Electrochemistry

A new electrochemical aptasensor based on gold/nitrogen-doped carbon nano-onions for the detection of Staphylococcus aureus

Esmail Sohouli et al.

Summary: Staphylococcus aureus (S. aureus) is a common bacterial pathogen that causes infections. A sensitive aptasensor was developed using carbon nano-onions, gold nanoparticles, and modified carbon electrodes for rapid detection of S. aureus. The aptasensor showed good repeatability and stability.

ELECTROCHIMICA ACTA (2022)

Add to Collection
Article Pharmacology & Pharmacy

Current and future perspectives of multifunctional magnetic nanoparticles based controlled drug delivery systems

Hira Aslam et al.

Summary: This article discusses the importance of magnetic nanoparticle-based drug delivery systems (MDDSs) in unique medical applications. MDDSs have superior biocompatibility and versatile loading capabilities, and they offer stronger targeting power and fewer side effects compared to other delivery systems. The article also addresses the challenges and latest developments in surface alterations and functionalization of MDDSs, and highlights the use of MDDSs in cancer detection and therapy.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)

Add to Collection
Article Pharmacology & Pharmacy

Aptamer-conjugated gold nanoparticles for targeted paclitaxel delivery and photothermal therapy in breast cancer

Jamileh Kadkhoda et al.

Summary: This study successfully developed a targeted photothermal therapy with a multifunctional drug delivery platform. The Mucin1 (MUC1) aptamer-modified poly (ethylene glycol)-gold nanoparticle system loaded with Paclitaxel (PTX) showed selective cytotoxicity towards MUC1-positive breast cancer cells and exhibited excellent cellular uptake ability when combined with near-infrared (NIR) irradiation. The synergistic effect of PTX/PEG-AuNPs@antiMUC1 was observed, leading to increased cell death compared to either photothermal therapy or chemotherapy alone. Protein expression analysis confirmed the potential of this synergistic combinational system in cancer therapy.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)

Add to Collection
Article Pharmacology & Pharmacy

Folate-targeted doxorubicin delivery to breast and cervical cancer cells using a chitosan-gold nano-delivery system

Jude Akinyelu et al.

Summary: This study reports the synthesis of a gold nanoparticle-based delivery system for doxorubicin (DOX) to cancer cells. The functionalized DOX-nanoparticles showed higher chemotherapeutic activity and potential for clinical application.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)

Add to Collection
Article Chemistry, Analytical

Sensitivity of photoelctrocehmical aptasensor using spiral nanorods for detecting antiobiotic levels in experimental and real samples

Yimeng Sun et al.

Summary: This study utilized a photoelectrochemical aptasensor to successfully detect chloramphenicol, demonstrating its potential in antibiotic monitoring. The nanoarrays based on TiO2@MoS2 showed excellent biochemical stability, allowing for accurate detection of chloramphenicol content within the range of 0.1 pM to 1 mu M.

TALANTA (2022)

Add to Collection
Review Chemistry, Physical

Chemical Functionalities of 3-aminopropyltriethoxy-silane for Surface Modification of Metal Oxide Nanoparticles

Wenyu Zhang et al.

Summary: 3-Aminopropyltriethoxysilane (APTES) is an important silicon compound used for modifying metal oxide nanoparticle surfaces, enhancing their dispersibility and antibacterial properties. APTES-modified MONPs have various applications in electrochemical sensors, catalysts, and Pickering emulsions.

SILICON (2022)

Add to Collection
Review Chemistry, Multidisciplinary

Thiolated Nanoparticles for Biomedical Applications: Mimicking the Workhorses of Our Body

Nathalie Hock et al.

Summary: This review discusses the interface between thiol chemistry and nanoparticles, highlighting the various functionalities gained by thiolation. These include enhanced bio- and mucoadhesive properties, improved cellular uptake, and permeation enhancement. Various applications such as drug delivery, targeted therapy, and diagnostics can benefit from thiolated nanoparticles.

ADVANCED SCIENCE (2022)

Add to Collection
Article Nanoscience & Nanotechnology

Surface Plasmon Resonance Immunosensor with Antibody-Functionalized Magnetoplasmonic Nanoparticles for Ultrasensitive Quantification of the CD5 Biomarker

Asta Kausaite-Minkstimiene et al.

Summary: A surface plasmon resonance (SPR) immunosensor signal amplification strategy based on antibody-functionalized gold-coated magnetic nanoparticles (mAuNPs) was developed for ultrasensitive and quantitative detection of the CD5 biomarker. The sandwich immunoassay utilizing mAuNPs-anti-CD5(2B) significantly improved the detection sensitivity and showed satisfactory performance in human blood serum.

ACS APPLIED MATERIALS & INTERFACES (2022)

Add to Collection
Review Biotechnology & Applied Microbiology

Marine biological macromolecules as matrix material for biosensor fabrication

Namita Bedi et al.

Summary: Marine organisms provide natural products with biological activities, making them potential sources for biomaterials and biosensors. This review focuses on the properties and applications of marine biomaterials in the design and development of biosensors, highlighting their advantages in terms of specificity, selectivity, biocompatibility, thermal stability, and cost-effectiveness.

BIOTECHNOLOGY AND BIOENGINEERING (2022)

Add to Collection
Article Pharmacology & Pharmacy

Functionalized multiwalled carbon nanotube-ethosomes for transdermal delivery of ketoprofen: Ex vivo and in vivo evaluation

Lijuan Ye et al.

Summary: A hybrid nanocarrier was developed to facilitate transdermal delivery of drugs. The f-MWCNTs-KP-ES preparation showed sustained release effect and faster skin penetration rate compared to commercial gel. Fluorescence microscopy and in vivo pharmacokinetic experiments confirmed the faster and deeper penetration of f-MWCNTs-RB-ES. The overall data demonstrate the promising transdermal drug delivery system of f-MWCNTs composite ethosomes formulation.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)

Add to Collection
Article Materials Science, Multidisciplinary

N-acetyl-D-glucosamine decorated nano-lipid-based carriers as theranostics module for targeted anti-cancer drug delivery

Rahul Kumar et al.

Summary: This study aimed to engineer N-acetyl-D-glucosamine (NADG) coupled quercetin-loaded nano-lipid-based carriers (NADG-Q-NLBCs) for targeting breast cancer. The constructed nano-bioconjugate was characterized and the in vitro drug release profiles were examined. Results showed that NADG-Q-NLBCs exhibited higher cytotoxicity and induced apoptosis in breast cancer cells in a targeted manner.

MATERIALS CHEMISTRY AND PHYSICS (2022)

Add to Collection
Article Chemistry, Multidisciplinary

CuO Nanozymes as Multifunctional Signal Labels for Efficiently Quenching the Photocurrent of ZnO/Au/AgSbS2 Hybrids and Initiating a Strong Fluorescent Signal in a Dual-Mode Microfluidic Sensing Platform

Tingting Wu et al.

Summary: A novel dual-mode microfluidic sensing platform based on CuO nanozymes as a photoelectrochemical (PEC)-fluorescent (FL) multifunctional signal label was developed for ultrasensitive neuron specific enolase (NSE) detection. The platform utilized ZnO/Au/AgSbS2 hybrids as a sensing matrix to provide a stable photocurrent, and the controlled synthesis of photoactive ZnO nanoflowers (NFs) was successfully conducted using a microfluidic reactor. CuO nanozymes were employed to catalytically oxidize ascorbic acid (AA) and quench the PEC signals, while initiating FL signals through reaction with o-phenylenediamine. The platform exhibited wide linear ranges and low detection limits for both PEC and FL techniques, enabling sensitive detection of NSE.

ACS SENSORS (2022)

Add to Collection
Review Pharmacology & Pharmacy

Challenges to perform an efficiently gene therapy adopting non-viral vectors: Melanoma landscape

Juliana Santos Rosa Viegas et al.

Summary: Gene therapy is an alternative treatment for melanoma, requiring the use of vectors for in vivo therapy. Non-viral vectors can ensure biological effects of DNA or RNA, but face challenges such as administration, vector choice, preparation processes, effectiveness, safety, and pre-clinical/clinical aspects.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)

Add to Collection
Review Pharmacology & Pharmacy

Polymer based sustained drug delivery to the ocular posterior segment: barriers and future opportunities for the treatment of neovascular pathologies

Rasha A. Alshaikh et al.

Summary: There is a growing interest in developing sustained, non-invasive delivery systems for treating chronic neovascular ocular diseases. This review critically examines the current treatments and discusses various sustained drug delivery approaches, including novel polymeric technologies, their mechanisms of sustained release, and considerations for translation.

ADVANCED DRUG DELIVERY REVIEWS (2022)

Add to Collection
Article Chemistry, Applied

Novel chitosan-graphene quantum dots composite for therapeutic delivery and tracking through enzymatic stimuli response

B. N. Kumara et al.

Summary: This study reports the design of highly efficient and biocompatible nanocomposites for drug delivery and tracking. A proof-of-concept was demonstrated for the delivery of an anti-glaucoma drug using a novel nanocomposite, with successful drug delivery and intercellular tracking observed. The nanocomposite also showed excellent cell viability and protected cells from oxidative injury.

CARBOHYDRATE POLYMERS (2022)

Add to Collection
Article Chemistry, Analytical

Electrochemical DNA Biosensor Based on Immobilization of a Non-Modified ssDNA Using Phosphoramidate-Bonding Strategy and Pencil Graphite Electrode Modified with AuNPs/CB and Self-Assembled Cysteamine Monolayer

Hamza Moustakim et al.

Summary: This study presents an alternative method for immobilizing DNA capture probes, using a phosphoramidate bond to attach non-modified ssDNA to a modified electrode. The technique offers a cost-effective and versatile approach for the fabrication of DNA biosensors, with potential applications in medical diagnostics and environmental monitoring.

SENSORS (2022)

Add to Collection
Article Chemistry, Multidisciplinary

SARS-CoV-2 Virus Detection Via a Polymeric Nanochannel-Based Electrochemical Biosensor

Amane Shiohara et al.

Summary: The development of simple, cost-effective, rapid, and quantitative diagnostic tools is crucial for monitoring infectious COVID-19 disease. This study demonstrates a unique approach to fabricate a nanochannel-based electrochemical biosensor that can detect the entire SARS-CoV-2 virus instead of virus fragments. The biosensor shows a low limit of detection and a wide detection range, and is able to differentiate saliva samples with SARS-CoV-2 from those without, showing potential for translation into a point-of-care biosensor product.

SMALL (2022)

Add to Collection
Article Chemistry, Analytical

An ultrasensitive and dual-recognition SERS biosensor based on Fe3O4@Au-Teicoplanin and aptamer functionalized Au@Ag nanoparticles for detection of Staphylococcus aureus

Xiaoyu Qi et al.

Summary: An ultrasensitive and dual-recognition surface-enhanced Raman scattering (SERS) biosensor has been developed for the detection of Staphylococcus aureus (S. aureus). The biosensor utilizes teicoplanin (Tcp) functionalized gold-coated magnet nanoparticles (Fe3O4@Au-Tcp NPs) as the capture probe and S. aureus aptamer (Apt) functionalized silver coated gold nanoparticles (Au@Ag-DTNB-Apt NPs) as the signal probe. The biosensor demonstrates high sensitivity and specificity due to the SERS enhancement from the hot spot effect between Au NPs and Au@Ag NPs, as well as the dual-recognition ability based on Tcp and Apt. The biosensor is capable of detecting S. aureus in milk and orange juice samples.

TALANTA (2022)

Add to Collection
Article Biotechnology & Applied Microbiology

Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives

Shno Asad et al.

Summary: Oral drug delivery is the preferred route due to patient compliance and convenience, but nanomedicine for this route is mainly under development for gastrointestinal diseases. Inorganic nanoparticles show promise for oral drug delivery, but they face challenges in the complex physiological conditions of the gastrointestinal tract. Understanding the interaction between inorganic nanoparticles and the dynamic gastrointestinal environment can aid in the development of efficient oral nanomedicine.

CURRENT OPINION IN CHEMICAL ENGINEERING (2022)

Add to Collection
Article Materials Science, Multidisciplinary

Efficient drug delivery by polyethylenimine capped CdSe/ZnS quantum dots and their biological activity

Lin -Song Li et al.

Summary: In this study, the research team developed a CdSe/ZnS quantum dot nano-drug delivery system that efficiently inhibited the proliferation of various cancer cells. The system exerted anti-cancer effects through the regulation of reactive oxygen species and protein expression, and showed promising therapeutic efficacy and biosafety in a mouse model.

MATERIALS & DESIGN (2022)

Add to Collection
Article Nanoscience & Nanotechnology

Stealth oxime ether lipid vesicles promote delivery of functional DsiRNA in human lung cancer A549 tumor bearing mouse xenografts

Anu Puri et al.

Summary: This study explores the in vivo utility of hydroxylated oxime ether lipids (OELs) and emphasizes the importance of surface modification for their in vivo applications. OEL4 formulations with DSPE-PEG350 and DSPE-PEG1000 promote gene silencing in cells. In vivo experiments demonstrate that OEL4 vesicles formulated with DSPE-PEG350 accumulate in tumors and exhibit higher tumor to liver ratios.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2022)

Add to Collection
Article Environmental Sciences

Development of magnetic nanoparticle assisted aptamer-quantum dot based biosensor for the detection of Escherichia coli in water samples

Chitvan Pandit et al.

Summary: In this study, a prototype biosensor using magnetic nanoparticles and fluorescent probes was developed for rapid and accurate detection of Escherichia coli in water and food samples.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

Add to Collection
Article Multidisciplinary Sciences

Gefitinib conjugated PEG passivated graphene quantum dots incorporated PLA microspheres for targeted anticancer drug delivery

Abhishek Gautam et al.

Summary: Graphene Quantum Dots passivated with Polyethylene Glycol were successfully synthesized and utilized for the synthesis of drug-loaded microspheres, showing potential for anticancer applications.

HELIYON (2022)

Add to Collection
Article Nanoscience & Nanotechnology

Smart Wearable Fluorescence Sensing of Bacterial Pathogens and Toxic Contaminants by Eu3+-Induced Sodium Alginate/Ag Nanoparticle Aggregates

Cuicui Li et al.

Summary: A wearable fabric sensing material based on fluorescent nanomaterials was prepared in this study. The material has the characteristics of being wearable, antibacterial, and biocompatible. Through fluorescence quenching, it can sensitively detect Escherichia coli and Staphylococcus aureus, and qualitatively detect selected transition metal ions.

ACS APPLIED NANO MATERIALS (2022)

Add to Collection
Article Nanoscience & Nanotechnology

Conjugated Polymer Nanoparticles as a Universal High-Affinity Probe for the Selective Detection of Microplastics

Angela Awada et al.

Summary: Microplastic pollution is a global challenge that needs immediate mitigation. This study introduces a novel design for the selective detection of microplastics using fluorescent conjugated polymer nanoparticles. The nanoparticles show strong affinity for various types of plastics and can be used for the detection of microplastics in heterogeneous samples.

ACS APPLIED MATERIALS & INTERFACES (2022)

Add to Collection
Article Chemistry, Analytical

A novel FRET immunosensor for rapid and sensitive detection of dicofol based on bimetallic nanoclusters

Yi Pan et al.

Summary: In this study, a fluorescence immunosensing platform was developed for the rapid detection of dicofol using the Forster resonance energy transfer (FRET) effect between Au-Ag bimetallic nanoclusters (Au-Ag NCs) and Au nanoflowers (Au NFs). The method demonstrated high sensitivity and specificity, and achieved satisfactory recovery in tea samples, indicating its potential for on-site and portable detection methods.

ANALYTICA CHIMICA ACTA (2022)

Add to Collection
Article Chemistry, Analytical

Smartphone-Based Electrochemical Immunoassay for Point-of-Care Detection of SARS-CoV-2 Nucleocapsid Protein

Ruijin Zeng et al.

Summary: This study presents a smartphone-based electrochemical immunoassay that is ultrasensitive for rapid, low-cost, and easy detection of the SARS-CoV-2 nucleocapsid protein. The method utilizes the interaction between gold nanoparticles on the electrode surface and antibodies to detect the presence of the protein. Additionally, the method allows for wireless data transmission and calculation of results using a smartphone, making it convenient and efficient.

ANALYTICAL CHEMISTRY (2022)

Add to Collection
Review Chemistry, Multidisciplinary

Emerging Trends in Cross-Coupling: Twelve-Electron-Based L1Pd(0) Catalysts, Their Mechanism of Action, and Selected Applications

Sharbil J. Firsan et al.

Summary: Monoligated palladium(0) species, L1Pd(0), are the most active catalytic species in cross-coupling reactions. Highly active but unstable L1Pd(0) catalysts can be generated from stable precatalysts. The size of the ligand plays a crucial role in the formation of L1Pd(0), and it can be precisely formed from the precatalyst using various technologies.

CHEMICAL REVIEWS (2022)

Add to Collection
Article Pharmacology & Pharmacy

Design of slow-release methotrexate drug delivery system using PHBV magnetic nanoparticles and evaluation of its cytotoxicity

Negin Baqeri et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)

Add to Collection
Article Pharmacology & Pharmacy

pH/NIR-responsive nanocarriers based on mesoporous polydopamine encapsulated gold nanorods for drug delivery and thermo-chemotherapy

Zehua Han et al.

Summary: In this study, gold nanorods were encapsulated in mesoporous polydopamine shells to create an ideal photothermal composite and drug delivery carrier with excellent photothermal properties and biocompatibility. Further sealing of the pore channels using polyethyleneimine resulted in a pH-/NIR-responsive nanocarrier with high drug loading capacities. The carrier demonstrated significant anticancer effects in vitro, showing promise as a nanoplatform for multifunctional cancer therapy in the future.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)

Add to Collection
Article Chemistry, Multidisciplinary

Facile, rapid and efficient isolation of circulating tumor cells using aptamer-targeted magnetic nanoparticles integrated with a microfluidic device

Abolghasem Abbasi Kajani et al.

Summary: A facile and sensitive method for the detection and isolation of circulating tumor cells (CTCs) was developed using aptamer-targeted magnetic nanoparticles (Apt-MNPs) in conjugation with a microfluidic device. The method showed high capture efficiency and potential for the detection and capture of CTCs.

RSC ADVANCES (2022)

Add to Collection
Review Chemistry, Multidisciplinary

Putting precision and elegance in enzyme immobilisation with bio-orthogonal chemistry

Xiaolin Pei et al.

Summary: This review focuses on recent advances in the highly precise immobilization of enzymes using bio-orthogonal chemistry in conjunction with rec-DNA. By combining production, purification and immobilization of enzymes in a single unit operation, cost-effective enzyme immobilization is achieved with a high degree of precision.

CHEMICAL SOCIETY REVIEWS (2022)

Add to Collection
Article Engineering, Electrical & Electronic

Non-faradaic electrochemical impedance spectroscopy analysis of C-MEMS derived bio-modified glassy carbon electrode

Rhea Patel et al.

Summary: In this study, a carbon-microelectromechanical systems derived glassy carbon electrode (GCE) was developed for non-faradaic electrochemical impedance spectroscopy (nf-EIS) measurement to detect changes in electrode interfacial upon biomodification. The study focused on the immobilization of DNA on the GCE and aimed to understand the electrical signatures during bio-modification of electrodes.

JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2022)

Add to Collection
Article Chemistry, Physical

Surface functionalization of graphene oxide with tannic acid: Covalent vs non-covalent approaches

Carlos Sainz-Urruela et al.

Summary: Graphene oxide (GO) has attracted significant interest in material science, biomedicine, and biotechnology due to its exceptional physical properties and surface functionalization capacity. In this study, a simple and environmentally friendly method was developed to prepare surface-functionalized GO nanosheets using tannic acid (TA) as a biological macro-molecule. The covalent grafting of TA improved the hydrophobicity and dispersion of GO in organic solvents, while also acting as a crosslinker to enhance thermal stability and antibacterial properties. This research emphasizes the potential of TA for the exfoliation and functionalization of GO, as well as its applications in biomedicine and the development of green nanocomposites.

JOURNAL OF MOLECULAR LIQUIDS (2022)

Add to Collection
Article Nanoscience & Nanotechnology

Cesium-Doped Graphene Quantum Dots as Ratiometric Fluorescence Sensors for Blood Glucose Detection

Jialin Wen et al.

Summary: Developing a highly sensitive fluorescence probe using cesium-doped graphene quantum dots (Cs-GQDs) for the detection of H2O2 and glucose has been achieved, showing promising potential for clinical diagnostics and research.

ACS APPLIED NANO MATERIALS (2021)

Add to Collection
Article Biophysics

Encapsulating enzyme into metal-organic framework during in-situ growth on cellulose acetate nanofibers as self-powered glucose biosensor

Xin Li et al.

Summary: This study developed a highly flexible electrode for reliable Enzymatic Biofuel Cells, which showed excellent stability in continuous long-term monitoring, potentially inspiring the application of enzymatic biosensors in biometrics, chronic disease management, and clinical diagnosis.

BIOSENSORS & BIOELECTRONICS (2021)

Add to Collection
Article Materials Science, Ceramics

Effect of rosemary extract on the microstructure, phase evolution, and magnetic behavior of cobalt ferrite nanoparticles and its application on anti-cancer drug delivery

Meysam Ghanbari et al.

Summary: The study synthesized cobalt ferrite nanoparticles via a modified sol-gel method, with single-phase spinel cobalt ferrite nanoparticles having an average crystallite size of about 33 nm and a cubic crystal structure. Coating the nanoparticles with an antioxidant drug showed biocompatibility and cytotoxicity against breast cancer cell lines.

CERAMICS INTERNATIONAL (2021)

Add to Collection
Article Biophysics

All-sealed paper-based electrochemiluminescence platform for on-site determination of lead ions

Lin Zhu et al.

Summary: An all-sealed paper-based electrochemiluminescence platform was developed for sensitive analysis of lead ions, combining convenient plastic packaging technology. The platform achieved wide linear relationship and low detection limit for rapid detection of heavy metal ions, showing promise for on-site contamination analysis in the future.

BIOSENSORS & BIOELECTRONICS (2021)

Add to Collection
Article Materials Science, Multidisciplinary

Facile approach for the synthesis of spherical mesoporous silica nanoparticles from sodium silicate

Jongkook Hwang et al.

Summary: The study introduced a facile synthetic method to prepare spherical mesoporous silica nanoparticles with tunable mesopores, utilizing acetic acid and PEG as key components to control the particle size and morphology.

MATERIALS LETTERS (2021)

Add to Collection
Article Materials Science, Biomaterials

MUC-1 aptamer conjugated InP/ZnS quantum dots/nanohydrogel fluorescent composite for mitochondria-mediated apoptosis in MCF-7 cells

Zahra Ranjbar-Navazi et al.

Summary: The combined use of NHGs and QDs has led to the development of a nanoscaled DDS with fluorescence imaging potential. The synthesized NHG-QDs nanosystem conjugated with an amino-modified MUC-1 aptamer and loaded with hydrophobic paclitaxel effectively targeted and inhibited breast cancer MCF-7 cells. Further loading of the inhibitor of LDH, sodium oxamate, allowed for disruption of glycolysis and induction of mitochondria-mediated apoptosis, proposing the NS as a robust theranostics for imaging and therapy of breast cancer and other solid tumors.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Add to Collection
Article Pharmacology & Pharmacy

Synthesis, characterization and evaluation of resveratrol-loaded functionalized carbon nanotubes as a novel delivery system in radiation enteropathy

Hussein E. Ali et al.

Summary: Radiation-induced enteropathy poses a challenge in radiotherapy, and resveratrol has potential pharmacological benefits but limited bioavailability. This study used MWCNTs-MAAc as carriers for controlled release of resveratrol, showing improved therapeutic potential in a rat model of radiation-induced enteropathy. The formulation was more efficient than free resveratrol due to prolonged release at the target site, highlighting its potential as an anti-inflammatory approach during radiotherapy.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

Add to Collection
Review Biotechnology & Applied Microbiology

Engineering precision nanoparticles for drug delivery

Michael J. Mitchell et al.

Summary: The development of nanoparticles has shown promising clinical applications, overcoming the limitations of therapeutic interventions and biological barriers. Precision therapies have enhanced treatment efficacy through personalized interventions. Advancements in nanoparticle design aim to optimize drug delivery, improving efficacy in general applications and enabling tailored designs for precision applications.

NATURE REVIEWS DRUG DISCOVERY (2021)

Add to Collection
Article Chemistry, Analytical

Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers

Shrishty Bakshi et al.

Summary: This study presents a rapid fabrication and proof-of-concept demonstration of an electrochemical immunosensor based on hyper-branched gold nanostructures for protein biomarker detection. By optimizing the process, efficient immobilization of proteins was achieved with a quick assay timing of 4 hours. The sensor showed a linear working range, low limit-of-detection, high selectivity in detecting target proteins, and good stability and reusability.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Add to Collection
Review Immunology

Nanomaterial Delivery Systems for mRNA Vaccines

Michael D. Buschmann et al.

Summary: This review highlights the recent success of mRNA vaccines in SARS-CoV-2 clinical trials, emphasizing the crucial role of lipid nanoparticles in the delivery systems and providing an analysis of the determinants of lipid nanoparticles' performance in mRNA vaccines.

VACCINES (2021)

Add to Collection
Article Chemistry, Multidisciplinary

Breathable Nanogenerators for an On-Plant Self-Powered Sustainable Agriculture System

Lingyi Lan et al.

Summary: The article introduces a waterproof and breathable triboelectric nanogenerator that can self-attach to plant leaves and harvest environmental energy from wind and raindrops. This generator can serve as a sustainable power supply for plant sensors, enabling real-time monitoring of plant health status.

ACS NANO (2021)

Add to Collection
Article Biophysics

Highly sensitive and specific graphene/TiO2 impedimetric immunosensor based on plant-derived tetravalent envelope glycoprotein domain III (EDIII) probe antigen for dengue diagnosis

Qi Yan Siew et al.

Summary: This study presents a novel impedimetric immunosensor design using plant-derived antigenic glycoprotein for the detection of dengue virus (DENV) IgG antibodies, showing high sensitivity and specificity. The developed immunosensor is proposed as a reliable and practical diagnostic tool for serological detection of dengue in realistic applications.

BIOSENSORS & BIOELECTRONICS (2021)

Add to Collection
Article Chemistry, Applied

Tumor microenvironment-responsive PEGylated heparin-pyropheophorbide-a nanoconjugates for photodynamic therapy`

Yahui Wu et al.

Summary: PEGylated heparin-based nanomedicines prepared in this study showed significant anticancer efficacy in vivo for photodynamic therapy. By modulating the conjugation of PEG moieties, the penetration and anticancer effects of the nanoparticles on tumor tissues were successfully enhanced.

CARBOHYDRATE POLYMERS (2021)

Add to Collection
Article Chemistry, Applied

pH-controlled nucleolin targeted release of dual drug from chitosan-gold based aptamer functionalized nano drug delivery system for improved glioblastoma treatment

Anbazhagan Sathiyaseelan et al.

Summary: A pH-responsive nano-drug delivery system was developed for enhanced glioblastoma treatment, showing improved cell death through dual drug release and confirmed drug internalization in cell organelles.

CARBOHYDRATE POLYMERS (2021)

Add to Collection
Article Chemistry, Analytical

Acetylcholinesterase entrapment onto carboxyl-modified single-walled carbon nanotubes and poly (3,4-ethylenedioxythiophene) nanocomposite, film electrosynthesis characterization, and sensor application for dichlorvos detection in apple juice

Oana Tutunaru et al.

Summary: The study developed a biosensor based on AChE, showing evidence of enzyme immobilization and conducting composite formation through electrochemical methods. The composite material exhibited high efficiency in retaining AChE activity and stability, as well as promoting electron transfer reaction to the gold electrode, making it suitable for detecting organophosphorus pesticides.

MICROCHEMICAL JOURNAL (2021)

Add to Collection
Article Pharmacology & Pharmacy

Mesoporous silica nanoparticles capped with chitosan-glucuronic acid conjugate for pH-responsive targeted delivery of 5-fluorouracil

Reema Narayan et al.

Summary: In this study, mesoporous silica nanoparticles (MSNs) capped with a chitosan-glucuronic acid (CHS-GCA) conjugate were designed for pH-responsive targeted delivery of 5-fluorouracil (5-FU). The encapsulation of 5-FU within MSNs and its controlled release were achieved through different techniques. The pH-sensitive CHS-GCA coating on MSNs resulted in higher release rates at lower pH levels, suggesting a pH-responsive behavior with potential for targeted drug delivery to tumor cells.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

Add to Collection
Article Polymer Science

Characterization of polyvinylpyrrolidone (PVP) with technetium-99m and its accumulation in mice

A. Massoud et al.

Summary: Polyvinylpyrrolidone (PVP) is commonly used in pharmaceutical and medical applications as a tablet binder and solubilizing agent. The stability and distribution of Tc-99m-PVP complex were studied, showing good stability properties in vitro and rapid excretion through the kidneys in normal mice.

JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY (2021)

Add to Collection
Article Materials Science, Biomaterials

One-minute and green synthesis of magnetic iron oxide nanoparticles assisted by design of experiments and high energy ultrasound: Application to biosensing and immunoprecipitation

Christian Hazael Perez-Beltran et al.

Summary: This study focused on the ultrafast and green synthesis of magnetic nanoparticles based on iron oxides using design of experiments and high energy sonochemical approach. Through optimization, a one-minute green synthesis was achieved, significantly reducing energy, solvents, reagents, and time consumption. Characterization results confirmed the proper formation and functionalization of the nanoparticles, which were successfully applied in biosensing and immunoprecipitation experiments.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Add to Collection
Article Chemistry, Applied

In vitro breast cancer targeting using Trastuzumab-conjugated mesoporous silica nanoparticles: Towards the new strategy for decreasing size and high drug loading capacity for drug delivery purposes in MSN synthesis

Mohammad Mozafarinia et al.

Summary: An efficient method for synthesizing biocompatible mesoporous silica nanoparticles with appropriate size and high drug loading capacity was introduced. The pH of the solution was controlled dominantly by tri-ethanolamine, which complexed with the ortho silicate functional group to regulate nanoparticle sizes; Ammonium nitrate was used for micellar template extraction, resulting in pore sizes and specific surface area higher than sodium chloride according to BET analysis.

MICROPOROUS AND MESOPOROUS MATERIALS (2021)

Add to Collection
Article Multidisciplinary Sciences

Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis

Linyang Fan et al.

Summary: The study demonstrates the conjugation of Ramucirumab to gold nanoparticles for improved delivery and enhanced therapeutic effects in gastric cancer cells. The combination leads to preferential toxicity and direct cytotoxic effects, potentially advancing the clinical application of gold nanomaterials in the diagnosis and treatment of gastric cancer.

NATURE COMMUNICATIONS (2021)

Add to Collection
Review Biotechnology & Applied Microbiology

Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles

Michele Schlich et al.

Summary: Ionizable lipid nanoparticles (LNPs) are the most advanced nano-delivery system for therapeutic nucleic acids, with the development of ionizable lipids playing a key role in their success. Overcoming challenges in RNA delivery, such as endosomal escape, is crucial for ensuring the therapeutic activity of RNA molecules. Understanding the mechanisms of endosomal escape and improving cytosolic delivery are important for developing future LNPs with enhanced nucleic acid delivery capabilities.

BIOENGINEERING & TRANSLATIONAL MEDICINE (2021)

Add to Collection
Review Engineering, Biomedical

PEG-based thermosensitive and biodegradable hydrogels

Jiayue Shi et al.

Summary: This paper outlines the recent progress of poly(ethylene glycol) (PEG)-based biodegradable thermosensitive hydrogels in the biomedical field, emphasizing their potential applications in drug release and cell growth. Thermosensitive hydrogels with designed and regulated properties exhibit excellent biocompatibility and degradability, providing a demonstration for the design of new thermogelling systems.

ACTA BIOMATERIALIA (2021)

Add to Collection
Article Biophysics

Encapsulation state of messenger RNA inside lipid nanoparticles

Mark L. Brader et al.

Summary: Understanding the structure and microenvironment of mRNA within lipid nanoparticles is crucial for unlocking their biomedical potential. By using the permeating cationic dye thionine as a contrasting agent, cryo-electron microscopy images reveal the location of mRNA within the nanoparticles, suggesting it may be in solvent-filled cavities or associated with lipids.

BIOPHYSICAL JOURNAL (2021)

Add to Collection
Article Chemistry, Multidisciplinary

APTES-Based Silica Nanoparticles as a Potential Modifier for the Selective Sequestration of CO2 Gas Molecules

Eduardo J. Cueto-Diaz et al.

Summary: The study characterized hybrid silica nanoparticles of 50 nm size with outstanding CO2 sorption capabilities and size homogeneity. Modification with 3-aminopropyl significantly enhanced CO2 sequestration, with larger micropore volume compared to 200 nm counterparts. Ideal absorption solution theory showed high CO2/N2 selectivity, surpassing other efficient microporous materials.

NANOMATERIALS (2021)

Add to Collection
Review Pharmacology & Pharmacy

Chitosan Nanoparticles at the Biological Interface: Implications for Drug Delivery

Noorjahan Aibani et al.

Summary: Chitosan, with its unique properties, is a valuable choice for nanoparticulate drug delivery applications, but its interactions at cellular and systemic levels require further study. The positive charge of chitosan allows for efficient attachment to cells, enhancing cellular uptake.

PHARMACEUTICS (2021)

Add to Collection
Review Multidisciplinary Sciences

Gold nanoparticles: Synthesis properties and applications

Ines Hammami et al.

Summary: In recent years, the development of nanotechnology has driven the preparation and application of gold nanoparticles, with researchers increasingly focusing on environmentally sustainable and green synthesis using non-toxic chemicals from natural sources. Gold nanoparticles have shown remarkable applications in diagnostics and therapeutics, including biosensor applications, tumor-targeting capability for cancer therapy, and precise drug delivery to diseased tissues.

JOURNAL OF KING SAUD UNIVERSITY SCIENCE (2021)

Add to Collection
Article Chemistry, Medicinal

Polyhydroxybutyrate-Based Nanocomposites for Bone Tissue Engineering

Anand Mohan et al.

Summary: Nanocomposites based on polyhydroxybutyrate (PHB) show promising applications in drug delivery and tissue engineering, particularly displaying enhanced properties in bone tissue engineering.

PHARMACEUTICALS (2021)

Add to Collection
Article Chemistry, Medicinal

Covalently Functionalized Carbon Nano-Onions Integrated Gelatin Methacryloyl Nanocomposite Hydrogel Containing γ-Cyclodextrin as Drug Carrier for High-Performance pH-Triggered Drug Release

Narsimha Mamidi et al.

Summary: In this study, a poly (n-(4-aminophenyl) methacrylamide) carbon nano-onions/gamma-cyclodextrin/DOX complex reinforced gelatin methacryloyl supramolecular hydrogel was successfully fabricated, showing enhanced mechanical properties and drug release performance. The obtained hydrogels also exhibited good biocompatibility with human fibroblast cells in cell experiments, suggesting their potential for controlled drug delivery systems in the future.

PHARMACEUTICALS (2021)

Add to Collection
Article Nanoscience & Nanotechnology

Self-Assembled Chromogenic Polymeric Nanoparticle-Laden Nanocarrier as a Signal Carrier for Derivative Binary Responsive Virus Detection

Indra Memdi Khoris et al.

Summary: This study utilizes a nanocarrier to achieve specific signal amplification in biosensors for the recognition of multiple viruses. By conjugating chromogens with antibodies specific to target viruses, the biosensor shows feasible detection of influenza virus subtypes with excellent specificity and sensitivity. The innovative approach demonstrates a synergy reaction for accurate diagnosis and surveillance of viruses.

ACS APPLIED MATERIALS & INTERFACES (2021)

Add to Collection
Article Chemistry, Multidisciplinary

Clustered Regularly Interspaced Short Palindromic Repeats-Mediated Amplification-Free Detection of Viral DNAs Using Surface-Enhanced Raman Spectroscopy-Active Nanoarray

Jin-Ha Choi et al.

Summary: A CRISPR-Cas12a-based nucleic acid amplification-free biosensor was developed in this study, combined with surface-enhanced Raman spectroscopy (SERS) technology, achieving high sensitivity detection of multiple viral DNAs without the need for amplification steps.

ACS NANO (2021)

Add to Collection
Article Chemistry, Multidisciplinary

Two-Dimensional-Material-Based Field-Effect Transistor Biosensor for Detecting COVID-19 Virus (SARS-CoV-2)

Parvin Fathi-Hafshejani et al.

Summary: This study utilizes FET based on semiconducting TMDC materials as a biosensor for rapid and sensitive detection of SARS-CoV-2, with a detection limit down to 25 fg/μL. Comprehensive theoretical and experimental studies show that TMDC-based 2D-FETs have the potential to serve as sensitive and selective biosensors for rapid detection of infectious diseases.

ACS NANO (2021)

Add to Collection
Article Engineering, Biomedical

Carboxyl-functionalized mesoporous silica nanoparticles for the controlled delivery of poorly water-soluble non-steroidal anti-inflammatory drugs

Kaijun Gou et al.

Summary: This study aimed to investigate the delivery of poorly water-soluble non-steroidal antiinflammatory drugs (NSAIDs) by carboxyl-functionalized mesoporous silica nanoparticles (MSN-COOH) with high specific surface area. The results showed that MSN-COOH had high drug loading capacity and exhibited good in vitro drug release properties, leading to improved bioavailability and strong anti-inflammatory effects in vivo.

ACTA BIOMATERIALIA (2021)

Add to Collection
Article Biophysics

Rapid and unamplified identification of COVID-19 with morpholino-modified graphene field-effect transistor nanosensor

Jiahao Li et al.

Summary: A rapid and unamplified nanosensing platform for detecting SARS-CoV-2 RNA in human throat swab specimens was developed, showing high sensitivity and rapid response. The sensor could accurately differentiate healthy individuals from infected individuals and had strong agreement with RT-PCR results.

BIOSENSORS & BIOELECTRONICS (2021)

Add to Collection
Article Biophysics

Nanomaterial-enhanced 3D-printed sensor platform for simultaneous detection of atrazine and acetochlor

Xiaofan Ruan et al.

Summary: The development of a Nanomaterial-enhanced multiplex electrochemical immunosensing (NEMEIS) system using 3D printing enabled simultaneous detection of atrazine and acetochlor with rapid, precise, economical, and portable capabilities. The system showed promising results for potential broad applications in chemical analysis, biosensors, and point-of-care monitoring.

BIOSENSORS & BIOELECTRONICS (2021)

Add to Collection
Article Chemistry, Physical

Design and mechanism of photocurrent-modulated graphene field-effect transistor for ultra-sensitive detection of DNA hybridization

Yang Sun et al.

Summary: In this study, a photocurrent-modulated FET sensor for DNA hybridization detection was proposed, achieving a detection limit down to attomolar concentrations. The sensor significantly enhances the response signal compared to traditional FET sensors, opening new avenues for further development in biosensing applications.

CARBON (2021)

Add to Collection
Article Engineering, Electrical & Electronic

Plasmonic Point-of-Care Device for Sepsis Biomarker Detection

Souvik Kundu et al.

Summary: The proposed point-of-care device for sepsis biomarker detection integrates surface plasmon resonance technology with microfluidics, providing high sensitivity and a low limit of detection. It offers an effective method for diagnosing and monitoring sepsis status.

IEEE SENSORS JOURNAL (2021)

Add to Collection
Review Materials Science, Biomaterials

Multifunctional nanoparticles as optical biosensing probe for breast cancer detection: A review

Neda Shahbazi et al.

Summary: This review summarizes the recent application of optical biosensing devices based on nanomaterials for improving breast cancer detection, discussing their pros and cons.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Add to Collection
Review Biotechnology & Applied Microbiology

mRNA vaccines for infectious diseases: principles, delivery and clinical translation

Namit Chaudhary et al.

Summary: mRNA vaccines have been established as a rapid, effective, and safe approach for protecting individuals from infectious diseases, especially during the COVID-19 pandemic. Further research is needed to optimize mRNA vaccine design, delivery, and applications for a range of infectious diseases.

NATURE REVIEWS DRUG DISCOVERY (2021)

Add to Collection
Article Engineering, Biomedical

Quantum Dots: Synthesis, Antibody Conjugation, and HER2-Receptor Targeting for Breast Cancer Therapy

Iqra Fatima et al.

Summary: Breast cancer research focuses on the biomarker HER2 and its application in targeted therapy. Nanotechnology and quantum dots have made significant advancements in imaging and treatment, promising to improve the efficacy of breast cancer treatment.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2021)

Add to Collection
Article Nanoscience & Nanotechnology

Functionalized multi-walled carbon nanotube/silver nanoparticle (f-MWCNT/AgNP) nanocomposites as non-enzymatic electrochemical biosensors for dopamine detection

Isa Anshori et al.

Summary: This study successfully synthesized f-MWCNT/AgNP nanocomposites and demonstrated their potential as biosensor materials for dopamine detection, with a low detection limit and high selectivity.

NANOCOMPOSITES (2021)

Add to Collection
Article Pharmacology & Pharmacy

Drug delivery of amoxicillin molecule as a suggested treatment for covid-19 implementing functionalized mesoporous SBA-15 with aminopropyl groups

Haneen F. Alazzawi et al.

Summary: This study evaluated the ability of an adapted SBA-15 surface as a sorbent to load the drug from an aqueous medium using a functionalization post-synthesis method, and analyzed the substance before and after functionalization through different characterization approaches. Experimental results revealed a strong influence of the amino-functional group on increasing the drug's load, with drug loading directly related to contact time and dose of NH2-SBA-15, but indirectly related to initial concentration.

DRUG DELIVERY (2021)

Add to Collection
Review Materials Science, Multidisciplinary

Nanomaterials: a review of synthesis methods, properties, recent progress, and challenges

Nadeem Baig et al.

Summary: Nanomaterials are a class of materials with exceptional properties that can be tuned through design, playing a crucial role in the advancement of nanotechnology. Various synthesis methods and unique features of nanomaterials have been discussed in this review, along with a brief history and future perspectives in the field.

MATERIALS ADVANCES (2021)

Add to Collection
Review Nanoscience & Nanotechnology

Drug Delivery With Carbon-Based Nanomaterials as Versatile Nanocarriers: Progress and Prospects

Sujit Kumar Debnath et al.

Summary: This passage discusses the research on the application of carbon-based nanomaterials in drug delivery, mentioning key factors and recent advancements, as well as recommending long-term toxicity studies before clinical application.

FRONTIERS IN NANOTECHNOLOGY (2021)

Add to Collection
Review Medicine, Research & Experimental

Nanotechnology and its use in imaging and drug delivery (Review)

Serjay Sim et al.

Summary: Nanotechnology exploits the unique properties of materials at the nanoscale, and has gained popularity in various industries. Nanomedicine, the application of nanotechnology in medicine and healthcare, has been used to combat common diseases with recent advances in imaging and drug delivery.

BIOMEDICAL REPORTS (2021)

Add to Collection
Article Nanoscience & Nanotechnology

Cucurbit[n]uril-Immobilized Sensor Arrays for Indicator-Displacement Assays of Small Bioactive Metabolites

Chunting Zhong et al.

Summary: The patterned immobilization of cucurbit[n]urils (CBn) into multiplexed microarrays enhances sensitivity and allows for the detection of small molecule analytes through indicator-displacement assays. Integration of CBn/indicator microarrays into microfluidic channels provides efficient real-time monitoring of the sensing process and reduces the required analyte volume. The concept is further extended to differential sensing of analytes on diplex or multiplex CBn/indicator microarrays, offering a route for multicomponent sensing of small molecule analytes in complex liquids.

ACS APPLIED NANO MATERIALS (2021)

Add to Collection
Article Chemistry, Multidisciplinary

Green and direct functionalization of poly (ethylene glycol) grafted polymers onto single walled carbon nanotubes: Effective nanocarrier for doxorubicin delivery

Xuan Thang Cao et al.

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY (2020)

Add to Collection
Article Materials Science, Biomaterials

The combination of Diels-Alder reaction and redox polymerization for preparation of functionalized CNTs for intracellular controlled drug delivery

Ziyang He et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Nanoparticle Beacons: Supersensitive Smart Materials with On/Off-Switchable Affinity to Biomedical Targets

Vladimir R. Cherkasov et al.

ACS NANO (2020)

Add to Collection
Article Chemistry, Analytical

Application of Biofunctionalized Magnetic Nanoparticles Based-Sensing in Abused Drugs Diagnostics

Serdar Sanli et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Article Chemistry, Analytical

Dual-Aptamer Modified Graphene Field-Effect Transistor Nanosensor for Label-Free and Specific Detection of Hepatocellular Carcinoma-Derived Microvesicles

Ding Wu et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Article Biophysics

Smartphone-assisted robust enzymes@MOFs-based paper biosensor for point-of-care detection

Xiaoxue Kou et al.

BIOSENSORS & BIOELECTRONICS (2020)

Add to Collection
Review Chemistry, Multidisciplinary

Hybrid carbon-based materials for gene delivery in cancer therapy

Sahar Taghavi et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Add to Collection
Article Materials Science, Biomaterials

pH and thermal dual-responsive poly(NIPAM-co-GMA)-coated magnetic nanoparticles via surface-initiated RAFT polymerization for controlled drug delivery

Ali Pourjavadi et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Magnetic Driven Nanocarriers for pH-Responsive Doxorubicin Release in Cancer Therapy

Joao Nogueira et al.

MOLECULES (2020)

Add to Collection
Article Chemistry, Analytical

Highly-efficient electrochemical label-free immunosensor for the detection of ochratoxin A in coffee samples

Kwanele Kunene et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

Add to Collection
Article Chemistry, Analytical

Quantum dots as nanolabels for breast cancer biomarker HER2-ECD analysis in human serum

Maria Freitas et al.

TALANTA (2020)

Add to Collection
Article Nanoscience & Nanotechnology

Electrospun CNT embedded ZnO nanofiber based biosensor for electrochemical detection of Atrazine: a step closure to single molecule detection

Patta Supraja et al.

MICROSYSTEMS & NANOENGINEERING (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Picomolar Biosensing and Conformational Analysis Using Artificial Bidomain Proteins and Terbium-to-Quantum Dot Forster Resonance Energy Transfer

Corentin Leger et al.

ACS NANO (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Selective Naked-Eye Detection of SARS-CoV-2 Mediated by N Gene Targeted Antisense Oligonucleotide Capped Plasmonic Nanoparticles

Parikshit Moitra et al.

ACS NANO (2020)

Add to Collection
Article Multidisciplinary Sciences

Remote biosensor for the determination of trypsin by using nanoporous anodic alumina as a three-dimensional nanostructured material

Mahmoud Amouzadeh Tabrizi et al.

SCIENTIFIC REPORTS (2020)

Add to Collection
Article Chemistry, Analytical

Robust Single-Molecule Enzyme Nanocapsules for Biosensing with Significantly Improved Biosensor Stability

Dhanjai et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Review Engineering, Biomedical

Tumor extravasation and infiltration as barriers of nanomedicine for high efficacy: The current status and transcytosis strategy

Quan Zhou et al.

BIOMATERIALS (2020)

Add to Collection
Article Biophysics

Synthesis of lactoferrin mesoporous silica nanoparticles for pemetrexed/ellagic acid synergistic breast cancer therapy

Omnia M. Ali et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2020)

Add to Collection
Review Chemistry, Inorganic & Nuclear

Heterogeneous surface architectured metal-organic frameworks for cancer therapy, imaging, and biosensing: A state-of-the-art review

Abhijeet Pandey et al.

COORDINATION CHEMISTRY REVIEWS (2020)

Add to Collection
Article Chemistry, Analytical

Pyridinium porphyrins and AuNPs mediated bionetworks as SPR signal amplification tags for the ultrasensitive assay of brain natriuretic peptide

Zhikang Zhu et al.

MICROCHIMICA ACTA (2020)

Add to Collection
Article Nanoscience & Nanotechnology

Ultrastable Plasmonic Bioink for Printable Point-Of-Care Biosensors

Ze Yin et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Add to Collection
Article Chemistry, Multidisciplinary

A Fiber Optic Interface Coupled to Nanosensors: Applications to Protein Aggregation and Organic Molecule Quantification

Daichi Kozawa et al.

ACS NANO (2020)

Add to Collection
Article Chemistry, Multidisciplinary

SAM Functionalized ZnO Nanowires for Selective Acetone Detection: Optimized Surface Specific Interaction Using APTMS and GLYMO Monolayers

Mandeep Singh et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Add to Collection
Article Chemistry, Analytical

Well-Orientation Strategy for Direct Immobilization of Antibodies: Development of the Immunosensor Using the Boronic Acid-Modified Magnetic Graphene Nanoribbons for Ultrasensitive Detection of Lymphoma Cancer Cells

Pegah Hashemi et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Article Engineering, Environmental

A smartphone-based quantitative point-of-care testing (POCT) system for simultaneous detection of multiple heavy metal ions

Zhenzhen Xu et al.

CHEMICAL ENGINEERING JOURNAL (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Surface-Confined Building of Au@Pt-Centered and Multi-G-Quadruplex/Hemin Wire-Surrounded Electroactive Super-nanostructures for Ultrasensitive Monitoring of Morphine

Wei Chen et al.

ACS SENSORS (2020)

Add to Collection
Article Chemistry, Physical

DNAzyme-Catalyzed Click Chemistry for Facilitated Immobilization of Redox Functionalities on Self-Assembled Monolayers

Ning Gan et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2020)

Add to Collection
Article Chemistry, Analytical

Direct Detection of Uranyl in Urine by Dissociation from Aptamer-Modified Nanosensor Arrays

Reut Meir et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Article Chemistry, Analytical

Engineering of a Dual-Recognition Ratiometric Fluorescent Nanosensor with a Remarkably Large Stokes Shift for Accurate Tracking of Pathogenic Bacteria at the Single-Cell Level

Yizhong Shen et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Article Chemistry, Analytical

Covalent Inhibitor-Based One-Step Method for Endothelin Receptor A Immobilization: from Ligand Recognition to Lead Identification

Xinfeng Zhao et al.

ANALYTICAL CHEMISTRY (2020)

Add to Collection
Article Materials Science, Biomaterials

Site-specific delivery of a natural chemotherapeutic agent to human lung cancer cells using biotinylated 2D rGO nanocarriers

Nitin Gupta et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Add to Collection
Article Materials Science, Biomaterials

pH-sensitive drug delivery based on chitosan wrapped graphene quantum dots with enhanced fluorescent stability

Yanshan Sheng et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Add to Collection
Article Biophysics

Blocking-free and self-contained immunoassay platform for one-step point-of-care testing

Qi Liu et al.

BIOSENSORS & BIOELECTRONICS (2020)

Add to Collection
Article Chemistry, Analytical

Bimetallic PtCu nanoparticles supported on molybdenum disulfide-functionalized graphitic carbon nitride for the detection of carcinoembryonic antigen

Yiju Song et al.

MICROCHIMICA ACTA (2020)

Add to Collection
Article Chemistry, Multidisciplinary

In Situ Detection of Neurotransmitters from Stem Cell-Derived Neural Interface at the Single-Cell Level via Graphene-Hybrid SERS Nanobiosensing

Jin-Ha Choi et al.

NANO LETTERS (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Glutathione-S-transferase Fusion Protein Nanosensor

Ryan M. Williams et al.

NANO LETTERS (2020)

Add to Collection
Article Materials Science, Biomaterials

Electrochemical Multiplexed Paper Nanosensor for Specific Dengue Serotype Detection Predicting Pervasiveness of DHF/DSS

Chaitali Singhal et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

Add to Collection
Article Chemistry, Analytical

One-Pot, In-Situ Synthesis of 8-Armed Poly(Ethylene Glycol)-Coated Ag Nanoclusters as a Fluorescent Sensor for Selective Detection of Cu2+

Xiaoyuan Zhang et al.

BIOSENSORS-BASEL (2020)

Add to Collection
Review Chemistry, Physical

Recent advances in chemical surface modification of metal oxide nanoparticles with silane coupling agents: A review

Fatemeh Ahangaran et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Bioinspired lipid-polysaccharide modified hybrid nanoparticles as a brain-targeted highly loaded carrier for a hydrophilic drug

Sara Hassan Omar et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Add to Collection
Article Multidisciplinary Sciences

Co-delivery of 5-fluorodeoxyuridine and doxorubicin via gold nanoparticle equipped with affibody-DNA hybrid strands for targeted synergistic chemotherapy of HER2 overexpressing breast cancer

Chao Zhang et al.

SCIENTIFIC REPORTS (2020)

Add to Collection
Article Pharmacology & Pharmacy

Surface modification of pralidoxime chloride-loaded solid lipid nanoparticles for enhanced brain reactivation of organophosphorus-inhibited AChE: Pharmacokinetics in rat

Daina N. Buzyurova et al.

TOXICOLOGY (2020)

Add to Collection
Article Engineering, Environmental

Strategies, challenges and opportunities of enzyme immobilization on porous silicon for biosensing applications

Rushikesh Fopase et al.

JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2020)

Add to Collection
Review Chemistry, Multidisciplinary

Pancake Bonding: An Unusual Pi-Stacking Interaction

Miklos Kertesz

CHEMISTRY-A EUROPEAN JOURNAL (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Improving the retention and reusability of Alpha-amylase by immobilization in nanoporous polyacrylamide-graphene oxide nanocomposites

Lucinda Mulko et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Add to Collection
Review Biochemical Research Methods

Lipid-polymer hybrid nanoparticles: Synthesis strategies and biomedical applications

Vivek Dave et al.

JOURNAL OF MICROBIOLOGICAL METHODS (2019)

Add to Collection
Article Chemistry, Analytical

Functionalized reduced graphene oxide as a lateral flow immuneassay label for one-step detection of Escherichia coli O157:H7

Vahid Shirshahi et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2019)

Add to Collection
Article Chemistry, Multidisciplinary

Ultrasensitive Monolayer MoS2 Field-Effect Transistor Based DNA Sensors for Screening of Down Syndrome

Jingxia Liu et al.

NANO LETTERS (2019)

Add to Collection
Article Multidisciplinary Sciences

An investigation into non-covalent functionalization of a single-walled carbon nanotube and a graphene sheet with protein G:A combined experimental and molecular dynamics study

Mohammad-Bagher Ebrahim-Habibi et al.

SCIENTIFIC REPORTS (2019)

Add to Collection
Article Nanoscience & Nanotechnology

Unprecedented Selectivity and Rapid Uptake of CuS Nanostructures toward Hg(II) Ions

Minghua Hu et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Add to Collection
Article Chemistry, Analytical

Rapid detection of pesticide residues using a silver nanoparticles coated glass bead as nonplanar substrate for SERS sensing

Jianshe Tang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

Add to Collection
Article Chemistry, Physical

An ultra-sensitive aptasensor based on carbon nanohorns/gold nanoparticles composites for impedimetric detection of carbendazim at picogram levels

Chengxi Zhu et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2019)

Add to Collection
Article Pharmacology & Pharmacy

Development of MCM-41 mesoporous silica nanoparticles as a platform for pramipexole delivery

Borislav Tzankov et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2019)

Add to Collection
Review Materials Science, Biomaterials

Functionalized mesoporous silica nanoparticles and biomedical applications

Thai Thanh Hoang Thi et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Add to Collection
Article Chemistry, Analytical

Controlled synthesis of Au@Pd core-shell nanocomposites and their application for electrochemical sensing of hydroquinone

Tingting Chen et al.

TALANTA (2019)

Add to Collection
Article Multidisciplinary Sciences

A self-assembled plasmonic optical fiber nanoprobe for label-free biosensing

Yuzhang Liang et al.

SCIENTIFIC REPORTS (2019)

Add to Collection
Article Biochemical Research Methods

Characterization of covalent crosslinking strategies for synthesizing DNA-based bioconjugates

Malithi P. Wickramathilaka et al.

JOURNAL OF BIOLOGICAL ENGINEERING (2019)

Add to Collection
Article Chemistry, Analytical

Optimized Immobilization of Biomolecules on Nonspherical Gold Nanostructures for Efficient Localized Surface Plasmon Resonance Biosensing

Ainash Garifullina et al.

ANALYTICAL CHEMISTRY (2019)

Add to Collection
Article Materials Science, Biomaterials

PEGylated graphene oxide-capped gold nanorods/silica nanoparticles as multifunctional drug delivery platform with enhanced near-infrared responsiveness

Zeer Qi et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Add to Collection
Article Polymer Science

3D printing of polylactic-co-glycolic acid fiber scaffolds using an antisolvent phase separation process

Anton Vladimirovich Mironov et al.

POLYMER (2019)

Add to Collection
Article Nanoscience & Nanotechnology

Metal-Organic-Framework-Based Enzymatic Microfluidic Biosensor via Surface Patterning and Biomineralization

Munirah Mohammad et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Add to Collection
Article Multidisciplinary Sciences

Impact of conjugation strategies for targeting of antibodies in gold nanoparticles for ultrasensitive detection of 17β-estradiol

Jairo Pinto Oliveira et al.

SCIENTIFIC REPORTS (2019)

Add to Collection
Article Chemistry, Inorganic & Nuclear

Cross-Coupling and Related Reactions: Connecting Past Success to the Development of New Reactions for the Future

Louis-Charles Campeau et al.

ORGANOMETALLICS (2019)

Add to Collection
Review Cell Biology

Protein PEGylation for cancer therapy: bench to bedside

Vijayalaxmi Gupta et al.

JOURNAL OF CELL COMMUNICATION AND SIGNALING (2019)

Add to Collection
Article Nanoscience & Nanotechnology

Evaluation of click chemistry microarrays for immunosensing of alpha-fetoprotein (AFP)

Seyed Mohammad Mahdi Dadfar et al.

BEILSTEIN JOURNAL OF NANOTECHNOLOGY (2019)

Add to Collection
Review Chemistry, Multidisciplinary

Applications of nanoparticles in biomedical imaging

Xiangjun Han et al.

NANOSCALE (2019)

Add to Collection
Article Chemistry, Physical

Phosphorus Doped MoS2 Nanosheet Promoted with Nitrogen, Sulfur Dual Doped Reduced Graphene Oxide as an Effective Electrocatalyst for Hydrogen Evolution Reaction

Kuppuswamy Guruprasad et al.

ACS APPLIED ENERGY MATERIALS (2019)

Add to Collection
Article Chemistry, Multidisciplinary

A novel enzymatic biosensor for detection of intracellular hydrogen peroxide based on 1-aminopyrene and reduced graphene oxides

Na Zou et al.

JOURNAL OF CHEMICAL SCIENCES (2019)

Add to Collection
Review Pharmacology & Pharmacy

Brief update on endocytosis of nanomedicines

Siddharth Patel et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Add to Collection
Review Engineering, Biomedical

Advances in Magnetic Nanoparticles for Biomedical Applications

Vanessa Fernandes Cardoso et al.

ADVANCED HEALTHCARE MATERIALS (2018)

Add to Collection
Article Nanoscience & Nanotechnology

Three-Dimensional DNA Origami as Programmable Anchoring Points for Bioreceptors in Fiber Optic Surface Plasmon Resonance Biosensing

Devin Daems et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Add to Collection
Article Chemistry, Multidisciplinary

Multifluorophore DNA Origami Beacon as a Biosensing Platform

Denis Selnihhin et al.

ACS NANO (2018)

Add to Collection
Article Pharmacology & Pharmacy

Tumor targeting via EPR: Strategies to enhance patient responses

Susanne K. Golombek et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

Add to Collection
Article Chemistry, Analytical

Multiplex Surface Plasmon Resonance Imaging-Based Biosensor for Human Pancreatic Islets Hormones Quantification

F. Rafael Castiello et al.

ANALYTICAL CHEMISTRY (2018)

Add to Collection
Article Chemistry, Analytical

Automated 3D-Printed Microfluidic Array for Rapid Nanomaterial-Enhanced Detection of Multiple Proteins

Karteek Kadimisetty et al.

ANALYTICAL CHEMISTRY (2018)

Add to Collection
Article Biochemical Research Methods

A Quantum Dot-Protein Bioconjugate That Provides for Extracellular Control of Intracellular Drug Release

Lauren D. Field et al.

BIOCONJUGATE CHEMISTRY (2018)

Add to Collection
Article Biophysics

DNA origami nanorobot fiber optic genosensor to TMV

Emanuela Toreili et al.

BIOSENSORS & BIOELECTRONICS (2018)

Add to Collection
Article Biophysics

Molybdenum disulfide field-effect transistor biosensor for ultrasensitive detection of DNA by employing morpholino as probe

Junchi Mei et al.

BIOSENSORS & BIOELECTRONICS (2018)

Add to Collection
Article Engineering, Environmental

Electrospun nanofibrous membranes containing epoxy groups and hydrophilic polyethylene oxide chain for highly active and stable covalent immobilization of lipase

Xinhua Liu et al.

CHEMICAL ENGINEERING JOURNAL (2018)

Add to Collection
Article Chemistry, Physical

Facile self-assembly of pyromellitic acid modified graphene oxide sheets into rhodamine B for highly selective luminescent sensing of Fe3+

Xiaoxiong Zhang et al.

JOURNAL OF ALLOYS AND COMPOUNDS (2018)

Add to Collection
Article Chemistry, Analytical

Effects of graphene on the microstructures of SnO2@rGO nanocomposites and their formaldehyde-sensing performance

Xiaoru Rong et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

Add to Collection
Article Chemistry, Analytical

Simultaneous fluorescence imaging monitoring of the programmed release of dual drugs from a hydrogel-carbon nanotube delivery system

Chang Wei et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

Add to Collection
Review Chemistry, Multidisciplinary

Synthesis of Alkanethiolate-Capped Metal Nanoparticles Using Alkyl Thiosulfate Ligand Precursors: A Method to Generate Promising Reagents for Selective Catalysis

Khin Aye San et al.

NANOMATERIALS (2018)

Add to Collection
Article Biochemical Research Methods

Versatile nano-platform for tailored immuno-magnetic carriers

Emanuela Bonaiuto et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2018)

Add to Collection
Article Nanoscience & Nanotechnology

A DNA Origami-Based Chiral Plasmonic Sensing Device

Yike Huang et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Add to Collection
Article Chemistry, Multidisciplinary

Versatile Types of DNA-Based Nanobiosensors for Specific Detection of Cancer Biomarker FEN1 in Living Cells and Cell-Free Systems

Hao Zhang et al.

NANO LETTERS (2018)

Add to Collection
Article Materials Science, Biomaterials

Enzymatic Nanocomposites with Radio Frequency Field-Modulated Activity

Yulia I. Andreeva et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2018)

Add to Collection
Article Nanoscience & Nanotechnology

Three-Dimensional Immunosensing Platform Based on a Hybrid Nanoflower for Sensitive Detection of α-Fetoprotein and Enterovirus 71

Yucheng Liu et al.

ACS APPLIED NANO MATERIALS (2018)

Add to Collection
Article Chemistry, Physical

Understanding the effect of size and shape of gold nanomaterials on nanometal surface energy transfer

Soumyadipta Rakshit et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2017)

Add to Collection
Review Chemistry, Multidisciplinary

The principles and applications of avidin-based nanoparticles in drug delivery and diagnosis

Akshay Jain et al.

JOURNAL OF CONTROLLED RELEASE (2017)

Add to Collection
Article Biochemical Research Methods

Site-selective orientated immobilization of antibodies and conjugates for immunodiagnostics development

Min Shen et al.

METHODS (2017)

Add to Collection
Article Biotechnology & Applied Microbiology

Lipid Nanoparticle Systems for Enabling Gene Therapies

Pieter R. Cullis et al.

MOLECULAR THERAPY (2017)

Add to Collection
Article Chemistry, Analytical

Development of a Sensitive Electrochemical Enzymatic Reaction-Based Cholesterol Biosensor Using Nano-Sized Carbon Interdigitated Electrodes Decorated with Gold Nanoparticles

Deepti Sharma et al.

SENSORS (2017)

Add to Collection
Article Chemistry, Analytical

A Third Generation Glucose Biosensor Based on Cellobiose Dehydrogenase Immobilized on a Glassy Carbon Electrode Decorated with Electrodeposited Gold Nanoparticles: Characterization and Application in Human Saliva

Paolo Bollella et al.

SENSORS (2017)

Add to Collection
Review Biophysics

Orientation and characterization of immobilized antibodies for improved immunoassays

Nicholas G. Welch et al.

BIOINTERPHASES (2017)

Add to Collection
Review Chemistry, Multidisciplinary

How to make nanobiosensors: surface modification and characterisation of nanomaterials for biosensing applications

Meral Yuce et al.

RSC ADVANCES (2017)

Add to Collection
Review Chemistry, Multidisciplinary

Mesoporous Silica Nanoparticles as Drug Delivery Vehicles in Cancer

Anna Watermann et al.

NANOMATERIALS (2017)

Add to Collection
Article Chemistry, Analytical

The influence of covalent immobilization conditions on antibody accessibility on nanoparticles

Bedabrata Saha et al.

ANALYST (2017)

Add to Collection
Review Chemistry, Multidisciplinary

Cellular uptake of nanoparticles: journey inside the cell

Shahed Behzadi et al.

CHEMICAL SOCIETY REVIEWS (2017)

Add to Collection
Article Nanoscience & Nanotechnology

Boosted Sensor Performance by Surface Modification of Bifunctional rht-Type Metal-Organic Framework with Nanosized Electrochemically Reduced Graphene Oxide

Cong Li et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Add to Collection
Review Chemistry, Multidisciplinary

Noncovalent Functionalization of Graphene and Graphene Oxide for Energy Materials, Biosensing, Catalytic, and Biomedical Applications

Vasilios Georgakilas et al.

CHEMICAL REVIEWS (2016)

Add to Collection
Article Materials Science, Biomaterials

Fluorescence enhancement of glutaraldehyde functionalized polyaniline nanofibers in the presence of aromatic amino acids

Rajiv Borah et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2016)

Add to Collection
Article Biotechnology & Applied Microbiology

Nanoparticles coated with high molecular weight PEG penetrate mucus and provide uniform vaginal and colorectal distribution in vivo

Katharina Maisel et al.

NANOMEDICINE (2016)

Add to Collection
Article Chemistry, Multidisciplinary

Self-encapsulation of a drug-containing ionic liquid into mesoporous silica monoliths or nanoparticles by a sol-gel process

David Brevet et al.

RSC ADVANCES (2016)

Add to Collection
Review Chemistry, Multidisciplinary

Role of functionalization: strategies to explore potential nano-bio applications of magnetic nanoparticles

Raghvendra A. Bohara et al.

RSC ADVANCES (2016)

Add to Collection
Review Pharmacology & Pharmacy

Multifunctional quantum dots-based cancer diagnostics and stem cell therapeutics for regenerative medicine

Daisuke Onoshima et al.

ADVANCED DRUG DELIVERY REVIEWS (2015)

Add to Collection
Review Biochemical Research Methods

Functionalizable low-fouling coatings for label-free biosensing in complex biological media: advances and applications

Hana Vaisocherova et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2015)

Add to Collection
Article Chemistry, Multidisciplinary

Multi-Functionalized Carbon Nano-onions as Imaging Probes for Cancer Cells

Marco Frasconi et al.

CHEMISTRY-A EUROPEAN JOURNAL (2015)

Add to Collection
Article Biochemistry & Molecular Biology

Classification of Magnetic Nanoparticle Systems-Synthesis, Standardization and Analysis Methods in the NanoMag Project

Sara Bogren et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Add to Collection
Article Biotechnology & Applied Microbiology

Principles of nanoparticle design for overcoming biological barriers to drug delivery

Elvin Blanco et al.

NATURE BIOTECHNOLOGY (2015)

Add to Collection
Article Chemistry, Multidisciplinary

Surface modification of metal oxides by polar molecules in a non-polar, polarizable solvent system

Arunava Agarwala et al.

CHEMICAL COMMUNICATIONS (2014)

Add to Collection
Review Biochemistry & Molecular Biology

Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation

Craig S. McKay et al.

CHEMISTRY & BIOLOGY (2014)

Add to Collection
Review Cell Biology

Nanoparticles and their applications in cell and molecular biology

Edina C. Wang et al.

INTEGRATIVE BIOLOGY (2014)

Add to Collection
Article Chemistry, Multidisciplinary

Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration

Sam Chen et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Add to Collection
Article Chemistry, Multidisciplinary

Dispersion quality of amine functionalized multiwall carbon nanotubes plays critical roles in polymerase chain reaction enhancement

Meral Yuce et al.

JOURNAL OF NANOPARTICLE RESEARCH (2014)

Add to Collection
Article Chemistry, Multidisciplinary

Supramolecular immobilization of bio-entities for bioelectrochemical applications

Michael Holzinger et al.

NEW JOURNAL OF CHEMISTRY (2014)

Add to Collection
Article Chemistry, Physical

End-on Covalent Antibody Immobilization on Dual Polarization Interferometry Sensor Chip for Enhanced Immuno-sensing

Hong Yan Song et al.

PLASMONICS (2014)

Add to Collection
Review Chemistry, Multidisciplinary

Glutaraldehyde in bio-catalysts design: a useful crosslinker and a versatile tool in enzyme immobilization

Oveimar Barbosa et al.

RSC ADVANCES (2014)

Add to Collection
Article Materials Science, Biomaterials

Ultrabright NIR fluorescent mesoporous silica nanoparticles

S. Palantavida et al.

JOURNAL OF MATERIALS CHEMISTRY B (2014)

Add to Collection
Review Pharmacology & Pharmacy

Carbon nanotubes as vectors for gene therapy: Past achievements, present challenges and future goals

Katie Bates et al.

ADVANCED DRUG DELIVERY REVIEWS (2013)

Add to Collection
Article Biophysics

Site-directed antibody immobilization techniques for immunosensors

Asta Makaraviciute et al.

BIOSENSORS & BIOELECTRONICS (2013)

Add to Collection
Review Chemistry, Multidisciplinary

Covalent chemistry on graphene

Chun Kiang Chua et al.

CHEMICAL SOCIETY REVIEWS (2013)

Add to Collection
Review Biochemistry & Molecular Biology

Molecular Motions in Functional Self-Assembled Nanostructures

Alexandre Dhotel et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Add to Collection
Article Polymer Science

Synthesis of polystyrene nanoparticles armoured with nanodimensional graphene oxide sheets by miniemulsion polymerization

S. H. Che Man et al.

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY (2013)

Add to Collection
Review Chemistry, Analytical

Immobilization Techniques in the Fabrication of Nanomaterial-Based Electrochemical Biosensors: A Review

William Putzbach et al.

SENSORS (2013)

Add to Collection
Review Nanoscience & Nanotechnology

Basics of magnetic nanoparticles for their application in the field of magnetic fluid hyperthermia

Vicky V. Mody et al.

EUROPEAN JOURNAL OF NANOMEDICINE (2013)

Add to Collection
Review Pharmacology & Pharmacy

Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers

Laura M. Ensign et al.

ADVANCED DRUG DELIVERY REVIEWS (2012)

Add to Collection
Review Pharmacology & Pharmacy

Luminescent quantum dots as platforms for probing in vitro and in vivo biological processes

Hedi Mattoussi et al.

ADVANCED DRUG DELIVERY REVIEWS (2012)

Add to Collection
Review Nanoscience & Nanotechnology

Beyond DNA origami: the unfolding prospects of nucleic acid nanotechnology

Nicole Michelotti et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2012)

Add to Collection
Article Biochemical Research Methods

The Red clover necrotic mosaic virus Capsid as a Multifunctional Cell Targeting Plant Viral Nanoparticle

Dustin M. Lockney et al.

BIOCONJUGATE CHEMISTRY (2011)

Add to Collection
Article Chemistry, Multidisciplinary

Different EDC/NHS Activation Mechanisms between PAA and PMAA Brushes and the Following Amidation Reactions

Cuie Wang et al.

LANGMUIR (2011)

Add to Collection
Proceedings Paper Instruments & Instrumentation

Spectroscopic and microscopic examination of protein adsorption and blocking of non-specific binding to silicon surfaces modified with APTES and GOPS

K. Awsiuk et al.

EUROSENSORS XXV (2011)

Add to Collection
Article Chemistry, Multidisciplinary

Kinetics of Diazonium Functionalization of Chemically Converted Graphene Nanoribbons

Alexander Sinitskii et al.

ACS NANO (2010)

Add to Collection
Article Chemistry, Applied

Bio-degradation study of colloidal mesoporous silica nanoparticles: Effect of surface functionalization with organo-silanes and poly(ethylene glycol)

Valentina Cauda et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2010)

Add to Collection
Review Nanoscience & Nanotechnology

Monodisperse magnetic nanoparticles for biodetection, imaging, and drug delivery: a versatile and evolving technology

Shivang R. Dave et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2009)

Add to Collection
Article Biochemical Research Methods

Efficient site-specific Labeling of proteins via cysteines

Younggyu Kim et al.

BIOCONJUGATE CHEMISTRY (2008)

Add to Collection
Review Chemistry, Multidisciplinary

Electrochemical glucose biosensors

Joseph Wang

CHEMICAL REVIEWS (2008)

Add to Collection
Article Chemistry, Physical

Silane ligand exchange to make hydrophobic superparamagnetic nanoparticles water-dispersible

Randy De Palma et al.

CHEMISTRY OF MATERIALS (2007)

Add to Collection
Article Chemistry, Physical

Suzuki coupling reactions for the surface functionalization of single-walled carbon nanotubes

Fuyong Cheng et al.

CHEMISTRY OF MATERIALS (2006)

Add to Collection
Article Chemistry, Physical

Triazole cycloaddition as a general route for functionalization of Au nanoparticles

DA Fleming et al.

CHEMISTRY OF MATERIALS (2006)

Add to Collection
Article Chemistry, Analytical

Surface modification for microreactor fabrication

Dorota G. Pijanowska et al.

SENSORS (2006)

Add to Collection
Article Biochemical Research Methods

Combined physical and chemical immobilization of glucose oxidase in alginate microspheres improves stability of encapsulation and activity

HG Zhu et al.

BIOCONJUGATE CHEMISTRY (2005)

Add to Collection
Review Chemistry, Multidisciplinary

Magnetic nanoparticles: Preparation methods, structure and properties

SP Gubin et al.

USPEKHI KHIMII (2005)

Add to Collection
Review Pharmacology & Pharmacy

DNA-based therapeutics and DNA delivery systems: A comprehensive review

SD Patil et al.

AAPS JOURNAL (2005)

Add to Collection
Article Chemistry, Multidisciplinary

Clicking functionality onto electrode surfaces

JP Collman et al.

LANGMUIR (2004)

Add to Collection
Article Chemistry, Physical

Single-molecule study of protein-protein interaction dynamics in a cell signaling system

X Tan et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2004)

Add to Collection
Article Chemistry, Multidisciplinary

Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy

MR Dreher et al.

JOURNAL OF CONTROLLED RELEASE (2003)

Add to Collection
Article Chemistry, Analytical

A quantitative assessment of heterogeneity for surface-immobilized proteins

RA Vijayendran et al.

ANALYTICAL CHEMISTRY (2001)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.