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4-oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal
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CHEMICAL RESEARCH IN TOXICOLOGY (2005)
Genotoxicity of 4-hydroxy-2-nonenal in human colon tumor cells is associated with cellular levels of glutathione and the modulation of glutathione S-transferase A4 expression by butyrate
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TOXICOLOGICAL SCIENCES (2005)
Involvement of reactive oxygen species in cyclic stretch-induced NF-κB activation in human fibroblast cells
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BRITISH JOURNAL OF PHARMACOLOGY (2005)
sn-position determination of phospholipid-linked fatty acids derived from erythrocytes by liquid chromatography electrospray ionization ion-trap mass spectrometry
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LIPIDS (2005)
Proteomic analysis of arginine adducts on glyoxal-modified ribonuclease
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MOLECULAR & CELLULAR PROTEOMICS (2004)
NF-κB activation mechanism of 4-hydroxyhexenal via NIK/IKK and p38 MAPK pathway
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FEBS LETTERS (2004)
Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Metabolism of lipid derived aldehyde, 4-hydroxynonenal in human lens epithelial cells and rat lens
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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Identification of intermediate pathways of 4-hydroxynonenal metabolism in the rat
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CHEMICAL RESEARCH IN TOXICOLOGY (2003)
Covalent adduction of nucleophilic amino acids by 4-hydroxynonenal and 4-oxononenal
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CHEMICO-BIOLOGICAL INTERACTIONS (2003)
Tyrosine phosphorylation of IκBα activates NFκB through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Measurement of 4-hydroxynonenal in small volume blood plasma samples: modification of a gas chromatographic-mass spectrometric method for clinical settings
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JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2002)
Reversible inactivation of the tumor suppressor PTEN by H2O2
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
8-(Hydroxymethyl)-3,N4-etheno-C, a potential carcinogenic glycidaldehyde product, miscodes in vitro using mammalian DNA polymerases
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BIOCHEMISTRY (2002)
Antioxidative function and substrate specificity of NAD(P)H-dependent alkenal/one oxidoreductase -: A new role for leukotriene B4 12-hydroxydehydrogenase/15-oxoprostaglandin 13-reductase
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release
C Ji et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2001)
4-hydroxynonenal prevents NO production in vascular smooth muscle cells by inhibiting nuclear factor-κB-dependent transcriptional activation of inducible NO synthase
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ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2001)
Peroxidation of linoleic acid and its relation to aging and age dependent diseases
G Spiteller
MECHANISMS OF AGEING AND DEVELOPMENT (2001)
IκB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal
C Ji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Apoptosis in raw 264.7 cells exposed to 4-hydroxy-2-nonenal:: Dependence on cytochrome c release but not p53 accumulation
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FREE RADICAL BIOLOGY AND MEDICINE (2001)
The reactive oxygen species- and Michael acceptor-inducible human aldo-keto reductase AKR1C1 reduces the α,β-unsaturated aldehyde 4-hydroacy-2-nonenal to 1,4-dihydroxy-2-nonene
ME Burczynski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
15-deoxy-Δ12,14-prostaglandin J2 inhibits multiple steps in the NF-κB signaling pathway
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The reactions of hypochlorous acid, the reactive oxygen species produced by myeloperoxidase, with lipids
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ACTA BIOCHIMICA POLONICA (2000)