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Article
Materials Science, Multidisciplinary
Tianji Liu et al.
Summary: Bioimaging guided photothermal therapy using stimulation-responsive assembled Ag2S vesicles offers a promising approach for cancer therapy. The vesicles show activation in acidic tumor tissues while remaining nonfunctional in normal tissues, with larger sizes enhancing tumor accumulation and controllable disassembly for improved lesion targeting. This innovative therapeutic strategy provides a new direction for activated NIR-II fluorescence imaging guided cancer therapy.
ADVANCED OPTICAL MATERIALS
(2021)
Review
Multidisciplinary Sciences
Xiulin Yi et al.
Summary: This study summarises strategies for achieving low-temperature PTT using nanomaterials, introduces the synthesis, characteristics, and applications of these nanoplatforms, and discusses the synergistic cancer therapeutic effect of combining PTT with other treatment modalities.
Article
Engineering, Biomedical
Shangyu Chen et al.
Summary: The authors developed ultrasmall TQFP-10 NPs with bright NIR-II fluorescence, prolonged blood circulation, and enhanced tumor accumulation for efficient orthotopic GBM imaging. Compared to traditional NPs, TQFP-10 NPs exhibited higher NIR-II fluorescence quantum yield and longer blood circulation half-life, leading to significantly improved tumor-to-normal tissue ratio in GBM imaging.
Article
Materials Science, Multidisciplinary
Hima Bindu Ruttala et al.
Summary: This study combined metal, polymer, and lipid nanoparticles to achieve enhanced therapeutic effects for cancer treatment using photothermal and photodynamic therapies, with improved cellular uptake by cancer cells and selective targeting of mitochondria through the mediation of triphenylphosphonium (TPP). The nanoparticles were found to accumulate predominantly in tumors in tumor-bearing mice, showing great improvement in efficacy compared to individual therapies.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Lorenzo Catti et al.
Summary: This study introduces a new set of supramolecular nanotools for the generation and modulation of noncovalent/covalent pentacene dimer singlet fission (SF), which can convert to triplet pairs and individual triplets even under high dilution conditions. The encapsulated pentacene dimers exhibit high quantum yields and the yield of individual triplets is enhanced upon encapsulation. The SF features of both types of pentacene dimers can be readily tuned by changing the polyaromatic panels of the capsule.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Weidong Ni et al.
Summary: Immunotherapy shows promise for tumor treatment, but its clinical effect is limited by tumor immunogenicity and the immunosuppressive microenvironment. Researchers combined metal-organic framework MIL-100 loaded with mitoxantrone (MTO) with photothermal-chemotherapy to enhance immunogenic cell death. The resulting MMH NPs, with dual therapeutic properties and imaging modes, showed high antitumor efficacy and immune effect when co-injected with anti-OX40 antibody in colorectal cancer. This novel combined therapeutic strategy is promising for future tumor therapy.
Article
Chemistry, Multidisciplinary
Qi Sun et al.
Summary: Through a localized coupling model, it has been demonstrated that the formation of a bright S-1 state in H-aggregate is due to the coupling between the low-lying intermolecular charge-transfer state and the upper bright Frenkel exciton, with the condition that the electron and hole transfer integrals are notably larger than the excitonic coupling. This theoretical finding not only explains recent experimental results but also provides insight into the compatibility between strong luminescence and high charge mobilities, which is important for OLETs and electrically pumped lasing.
Review
Chemistry, Multidisciplinary
Qiwei Tian et al.
Summary: Chemodynamic therapy (CDT) is a novel therapeutic modality that aims to destroy cancer cells using Fenton reactions without external energy input. Various strategies have been explored to enhance the efficiency of CDT, including increasing the production, accelerating generation, and enhancing efficacy of hydroxyl radicals.
Article
Chemistry, Multidisciplinary
Mengze Xu et al.
Summary: In this study, a theranostic nanoplatform called UCILA was developed to visually acquire comprehensive information of lung cancer and conduct synergistic photothermal therapy and tumor-targeting immunotherapy. The platform enables penta-modal imaging, temperature-feedback PTT, and real-time monitoring of tumor metabolic activity, demonstrating excellent capability for tumor ablation with minimal side effects.
Review
Chemistry, Multidisciplinary
Yunguang Zhang et al.
Summary: Photothermal therapy is a promising treatment for cancer, with photothermal nanomaterials in the NIR-I region attracting attention. The use of light in the NIR-II region allows for deeper tissue penetration, higher radiation limits, and greater tissue tolerance, showing greater potential in photothermal conversion. This review highlights the photothermal properties of various nanomaterials in the NIR-II region and their application prospects in photothermal therapy, sparking interest in the field of cancer treatment and nanomedicine.
FRONTIERS IN CHEMISTRY
(2021)
Review
Acoustics
Janek Groehl et al.
Summary: Photoacoustic imaging (PAI) is a promising emerging imaging modality that enables spatially resolved imaging of optical tissue properties. However, extracting relevant tissue parameters from raw data is difficult, leading to the application of deep learning methods in PAI. These methods have advantages like fast computation times and adaptability to various problems, facilitating clinical translation.
Article
Chemistry, Multidisciplinary
Yue He et al.
Summary: The article introduces a new type of CEAF probe that achieves high-contrast bioimaging in the tissue-transparent second near-infrared window through cell endocytosis. The probe is stable in water and blood, with potential applications in areas such as tumors and inflammation.
Review
Chemistry, Multidisciplinary
Shunjie Liu et al.
Summary: Aggregation-induced emission (AIE) is a cutting-edge technology for developing highly efficient NIR-II emitters and photothermal agents, with the optimization of multi-hierarchical structures and intramolecular motions balancing fluorescence imaging and photothermal therapy functions.
Review
Chemistry, Multidisciplinary
Xueze Zhao et al.
Summary: This review summarizes recent progress in developing photosensitizers (PSs) for photodynamic therapy, including enhanced tolerance, improved selectivity, and deep tissue applicability. PSs are classified based on molecular design and application, with strategies for designing and future perspectives briefly outlined.
CHEMICAL SOCIETY REVIEWS
(2021)
Article
Chemistry, Physical
Xiaozhen Li et al.
Summary: The synergistic effect of photodynamic therapy (PDT) and photothermal therapy (PTT) shows superior clinical application prospects compared to single PDT or PTT. By designing and synthesizing a near-infrared (NIR) small molecule (ETTC), multiple functions such as NIR-II fluorescence imaging, photoacoustic imaging, PTT, and PDT were successfully achieved and optimized. This work provides a novel perspective for the development of efficient and versatile biomedical applications in a single molecule.
NANOSCALE HORIZONS
(2021)
Article
Pharmacology & Pharmacy
Tuanwei Li et al.
Summary: A NIR (NIR-I) probe with intrinsic multifunctionality was synthesized and encapsulated in an amphiphilic polypeptide to create polymeric micelles serving as a nanotheranostic platform for NIR-II imaging-guided photothermal therapy (PTT) and photodynamic therapy (PDT). In vivo studies demonstrated the real-time monitoring of P@BDP accumulation in tumors and the highly effective synergistic phototherapy under NIR-II imaging-guided PTT/PDT combination therapy.
ADVANCED THERAPEUTICS
(2021)
Article
Chemistry, Multidisciplinary
Jingjing Liu et al.
ADVANCED FUNCTIONAL MATERIALS
(2020)
Article
Engineering, Biomedical
Po-Ming Chen et al.
Article
Chemistry, Multidisciplinary
Shanshan Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2020)
Article
Chemistry, Multidisciplinary
Qingfei Zhang et al.
Article
Chemistry, Multidisciplinary
Xiaolong Liang et al.
Article
Chemistry, Physical
Pouya Hosseini et al.
JOURNAL OF PHYSICAL CHEMISTRY C
(2020)
Review
Chemistry, Multidisciplinary
Edmundo G. Percastegui et al.
Article
Nanoscience & Nanotechnology
Quan Cheng et al.
ACS APPLIED BIO MATERIALS
(2020)
Article
Multidisciplinary Sciences
Yinxian Yang et al.
Review
Chemistry, Multidisciplinary
Eunbin Hwang et al.
CHEMICAL COMMUNICATIONS
(2020)
Review
Chemistry, Multidisciplinary
Zhongmin Tang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2019)
Review
Chemistry, Multidisciplinary
Yijing Liu et al.
CHEMICAL SOCIETY REVIEWS
(2019)
Article
Chemistry, Multidisciplinary
Dong Wang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Stan van Keulen et al.
JOURNAL OF NUCLEAR MEDICINE
(2019)
Article
Chemistry, Multidisciplinary
Wen Sun et al.
Article
Nanoscience & Nanotechnology
Weiqing Xu et al.
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Chemistry, Multidisciplinary
Qi Wang et al.
ADVANCED FUNCTIONAL MATERIALS
(2019)
Review
Chemistry, Multidisciplinary
Yong Fan et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2019)
Article
Chemistry, Multidisciplinary
Bei Liu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2019)
Review
Nanoscience & Nanotechnology
Jutaek Nam et al.
NATURE REVIEWS MATERIALS
(2019)
Article
Multidisciplinary Sciences
Shuai Gao et al.
NATURE COMMUNICATIONS
(2019)
Review
Engineering, Biomedical
Xiaoqin Qian et al.
Article
Chemistry, Multidisciplinary
Caixia Sun et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Review
Medicine, General & Internal
Evelien Dekker et al.
Review
Chemistry, Multidisciplinary
Qinrui Fu et al.
ADVANCED MATERIALS
(2019)
Article
Chemistry, Multidisciplinary
Yuyan Jiang et al.
ADVANCED MATERIALS
(2019)
Article
Biochemical Research Methods
Menghan Wang et al.
JOURNAL OF BIOPHOTONICS
(2019)
Article
Chemistry, Multidisciplinary
Peiran Zhao et al.
MATERIALS HORIZONS
(2019)
Review
Chemistry, Physical
Yan Lyu et al.
Article
Materials Science, Biomaterials
Yaoqi Li et al.
BIOMATERIALS SCIENCE
(2019)
Article
Nanoscience & Nanotechnology
Yu-Wei Tai et al.
ACS APPLIED MATERIALS & INTERFACES
(2018)
Article
Chemistry, Multidisciplinary
Shuyue Ye et al.
ADVANCED MATERIALS
(2018)
Review
Chemistry, Multidisciplinary
Xingshu Li et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2018)
Article
Engineering, Environmental
Ming Zhang et al.
CHEMICAL ENGINEERING JOURNAL
(2018)
Review
Chemistry, Multidisciplinary
Shuqing He et al.
CHEMICAL SOCIETY REVIEWS
(2018)
Article
Chemistry, Multidisciplinary
Qinglai Yang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2018)
Review
Chemistry, Multidisciplinary
Yuyan Jiang et al.
ACCOUNTS OF CHEMICAL RESEARCH
(2018)
Review
Medicine, Research & Experimental
Dong Wang et al.
Review
Chemistry, Multidisciplinary
Li-Jun Chen et al.
ACCOUNTS OF CHEMICAL RESEARCH
(2018)
Article
Chemistry, Multidisciplinary
Qiumei Di et al.
CHEMISTRY-A EUROPEAN JOURNAL
(2018)
Article
Engineering, Biomedical
Yuyan Jiang et al.
Article
Chemistry, Multidisciplinary
Xiao-Qiang Wang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2017)
Article
Chemistry, Multidisciplinary
Chao Yin et al.
ADVANCED FUNCTIONAL MATERIALS
(2017)
Article
Chemistry, Multidisciplinary
Chen Xie et al.
ADVANCED FUNCTIONAL MATERIALS
(2017)
Review
Chemistry, Multidisciplinary
Bryan Ronain Smith et al.
Article
Chemistry, Multidisciplinary
Yan Lyu et al.
Article
Chemistry, Multidisciplinary
William Cullen et al.
Review
Biochemical Research Methods
Judith Weber et al.
Article
Multidisciplinary Sciences
Jundong Shao et al.
NATURE COMMUNICATIONS
(2016)
Article
Engineering, Biomedical
Shazid Md Sharker et al.
Review
Chemistry, Physical
Frank C. Spano et al.
ANNUAL REVIEW OF PHYSICAL CHEMISTRY, VOL 65
(2014)
Article
Chemistry, Physical
Santanu Chakraborty et al.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2014)
Article
Chemistry, Multidisciplinary
Lun Li et al.
CHEMICAL COMMUNICATIONS
(2012)
Review
Multidisciplinary Sciences
Lihong V. Wang et al.
Review
Chemistry, Multidisciplinary
Yen-Ju Cheng et al.
