Journal
BIOLOGICALS
Volume 85, Issue -, Pages -Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biologicals.2023.101725
Keywords
Multi-drug resistant; Nano-emulsion; Bacteriophage; Formulations; Antibiotics
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Antibiotic resistance has become a major concern for global public health, and phage therapy is seen as an alternative for treating multidrug resistant bacterial infections. Nano-emulsion encapsulation is described as the best approach to maintain phage efficacy.
Antibiotic resistance has become the major concern for global public health. Phage therapy is being considered as an alternative for antibiotics to treat the multidrug resistant bacterial infections. Bacteriophage therapeutic developments has faced many challenges, including the drug formulations for sustainable phage delivery. The nano-emulsion platform has been described as the best approach to retain phage efficacy, shelf life and stability. Encapsulated phage drugs ensure stable delivery of phages to the target site and integrate in the system. In this review, our main focus is on the nano-emulsion encapsulation of bacteriophages and its effects towards the phage therapeutic development.
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