The Aortic Team Model and Collaborative Decision Pathways for the Management of Complex Aortic Disease: Clinical Practice Update From the Canadian Cardiovascular Society/Canadian Society of Cardiac Surgeons/Canadian Society for Vascular Surgery/Canad...

Review Cardiac & Cardiovascular Systems

Imaging surveillance for complications after primary surgery for type A aortic dissection

Samuel Heuts et al.

Summary: Acute type A aortic dissection (ATAAD) is a life-threatening condition that requires emergency surgery. Patients should undergo regular imaging examinations to evaluate the occurrence of complications.

HEART (2023)

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Article Genetics & Heredity

HTAD patient pathway: Strategy for diagnostic work-up of patients and families with (suspected) heritable thoracic aortic diseases (HTAD). A statement from the HTAD working group of VASCERN

Maryanne Caruana et al.

Summary: This document provides a patient pathway that improves care for patients with heritable thoracic aortic diseases (HTAD). It recommends referral to an expert center for evaluation based on specific criteria and suggests using transthoracic echocardiography for aortic imaging, with additional magnetic resonance imaging or computed tomography if necessary. Genetic testing should be considered for those with a high suspicion of underlying genetic aortopathy. The implementation of these strategies can standardize the diagnostic work-up and follow-up of patients with suspected HTAD and their relatives.

EUROPEAN JOURNAL OF MEDICAL GENETICS (2023)

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Review Cardiac & Cardiovascular Systems

A Systematic Review of Total Endovascular Aortic Arch Repair: A Promising Technology

Ameen M. Basha et al.

Summary: TEAAR is an emerging alternative for the treatment of aortic arch disease in high-risk patients. A systematic review of TEAAR was conducted to evaluate its early outcomes. The study found that TEAAR is mainly indicated for chronic arch dissection with degenerative aneurysmal disease and pure arch aneurysm.

CANADIAN JOURNAL OF CARDIOLOGY (2023)

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Article Rehabilitation

Adults with Loeys-Dietz syndrome and vascular Ehlers-Danlos syndrome: a cross-sectional study of patient experiences with physical activity

Heidi Johansen et al.

Summary: This study examined patient experiences with physical activity among individuals with Loeys-Dietz syndrome or vascular Ehlers-Danlos syndrome. Most patients have received advice regarding physical activity and made lifestyle modifications. However, a portion of patients have either excessive or insufficient physical activity levels. High physical activity levels are associated with lower scores on measures of fatigue severity and anxiety.

DISABILITY AND REHABILITATION (2022)

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Review Surgery

Angiotensin Receptor Blockers vs. Beta-Blocker Therapy for Marfan Syndrome: A Systematic Review and Meta-Analysis

Zhong Wang et al.

Summary: This study compared the efficacy and safety of different therapies for Marfan syndrome. The results showed that ARB-only therapy is not inferior to BB-only therapy, and ARB+BB therapy has superior therapeutic effects without significant adverse effects.

ANNALS OF VASCULAR SURGERY (2022)

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Editorial Material Cardiac & Cardiovascular Systems

Thoracic Aortic Diseases: What the Practicing Cardiologist Needs to Know

Jean-Francois Dorval et al.

CANADIAN JOURNAL OF CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Imaging and Surveillance of Chronic Aortic Dissection: A Scientific Statement From the American Heart Association

Dominik Fleischmann et al.

Summary: All patients surviving an acute aortic dissection need lifelong surveillance. However, there are currently no guidelines or recommendations for imaging surveillance in patients with chronic aortic dissection. Research suggests that imaging and computer simulations can predict aortic false lumen degeneration and biomechanical failure, which can improve risk assessment and inform personalized treatment strategies.

CIRCULATION-CARDIOVASCULAR IMAGING (2022)

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Review Cardiac & Cardiovascular Systems

Update on the molecular landscape of thoracic aortic aneurysmal disease

Ilse Luyckx et al.

Summary: This review discusses genetic discoveries, clinical challenges, and future molecular research directions in the field of Thoracic Aortic Aneurysms and Dissections (TAADs). Recent studies have identified new genes associated with TAAD risk, revealing potential therapeutic targets. Current evidence also suggests a complex interplay of genetic and environmental factors in TAAD disease.

CURRENT OPINION IN CARDIOLOGY (2022)

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Review Cardiac & Cardiovascular Systems

Aortopathy in pregnancy

Stephanie Louise Curtis et al.

Summary: Aortic dissection is a common cause of death in pregnancy. Early recognition and involvement of expert clinicians are essential for early diagnosis and care. Frequent imaging and good blood pressure control are key. Close surveillance and blood pressure control after delivery are crucial.

HEART (2022)

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Article Surgery

Mortality and Major Adverse Events Improve With Increased Institutional Experience for Fenestrated and Branched Endovascular Aortic Repair

Robert-James Doonan et al.

Summary: The study evaluated temporal trends in outcomes of fenestrated/branched endovascular aneurysm repair at the institution. Results showed an increase in comorbidities over time, while procedural metrics such as procedure time, contrast volume, and estimated blood loss decreased. Mortality and major adverse events decreased with increasing institutional experience, suggesting improvements in outcomes over time.

JOURNAL OF ENDOVASCULAR THERAPY (2022)

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Article Surgery

Risk factors associated with long-term mortality and complications after thoracoabdominal aortic aneurysm repair

Rodolfo Rocha et al.

Summary: The study aimed to determine the risk factors associated with late mortality or complications after endovascular or open repair of thoracoabdominal aortic aneurysms (TAAAs). The results showed that TAAA repair was associated with reduced long-term survival compared to the general population, and urgent or emergent repair was the most significant risk factor for late adverse events.

JOURNAL OF VASCULAR SURGERY (2022)

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Editorial Material Cardiac & Cardiovascular Systems

Hereditary thoracic aortic disease: How to save lives

Mary J. Roman et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2022)

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Review Surgery

An assessment of the current medical management of thoracic aortic disease: A patient-centered scoping literature review

Robert C. F. Pena et al.

Summary: Thoracic aortic aneurysm and dissection require comprehensive management by multidisciplinary providers, utilizing pharmacological agents, surgical interventions, and lifestyle modifications. Advancements in understanding the genetic, biochemical, and pathophysiological mechanisms behind these diseases have expanded potential targets for future therapeutic research.

SEMINARS IN VASCULAR SURGERY (2022)

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Review Surgery

The mental health impact of aortic dissection

Nicole Ilonzo et al.

Summary: Research on the impact of aortic dissection (AD) on mental health, both short-term and long-term, is lacking despite studies on surgical techniques and medical therapies. AD as a medical trauma has complex implications for identity and warrants further exploration. This topic has been identified as an area of interest for future research.

SEMINARS IN VASCULAR SURGERY (2022)

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Article Cardiac & Cardiovascular Systems

Determinants of outcomes following surgery for type A acute aortic dissection: the UK National Adult Cardiac Surgical Audit

Umberto Benedetto et al.

Summary: This study aimed to investigate the relationship between surgical outcomes of TAAAD patients in the UK and variables including patient characteristics, intraoperative factors, cardiac centers, and surgeons. The study found significant associations between age, malperfusion, left ventricular ejection fraction, previous cardiac surgery, preoperative mechanical ventilation, preoperative resuscitation, concomitant coronary artery bypass grafting, and surgical outcomes. Additionally, there was an inverse relationship between surgeon annual volume and outcomes.

EUROPEAN HEART JOURNAL (2022)

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Review Cardiac & Cardiovascular Systems

Risk profile analysis of uncomplicated type B aortic dissection patients undergoing thoracic endovascular aortic repair: Laboratory and radiographic predictors

Alexander Geragotellis et al.

Summary: There is currently a lack of clear clinical guidelines for selecting unTBAD patients for TEVAR based on risk stratification. However, certain clinical, laboratory, and morphological parameters can be used to identify high-risk patients. Further advancements in biomarkers and imaging techniques are expected to optimize risk-stratified treatment protocols.

JOURNAL OF CARDIAC SURGERY (2022)

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Review Cardiac & Cardiovascular Systems

Radiation safety for cardiovascular computed tomography imaging in paediatric cardiology: a joint expert consensus document of the EACVI, ESCR, AEPC, and ESPR

M. Francone et al.

Summary: This manuscript provides a comprehensive review of radiation dose management and cardiac computed tomography performance in the pediatric population with congenital and acquired heart disease, aiming to encourage informed imaging for indication-appropriate study quality at the lowest achievable dose.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING (2022)

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Editorial Material Cardiac & Cardiovascular Systems

The Aortic Wall Conundrum: Predicting Thoracic Aortic Disease Behaviour

Dominique Vervoort et al.

CANADIAN JOURNAL OF CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines

Eric M. Isselbacher et al.

Summary: The 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease provides recommendations for clinicians on the diagnosis, genetic evaluation, medical therapy, endovascular and surgical treatment, and long-term surveillance of patients with various clinical presentations of aortic disease. The guideline emphasizes the importance of shared decision making and institutional interventional volume and multidisciplinary expertise in the care of patients with aortic disease.

CIRCULATION (2022)

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Article Cardiac & Cardiovascular Systems

Comparative Risks of Initial Aortic Events Associated With Genetic Thoracic Aortic Disease

Ellen S. Regalado et al.

Summary: This study compares the risk of first aortic events among 7 genes for heritable thoracic aortic disease (HTAD) and variant types within each gene. The findings highlight significant differences in aortic event risk based on specific genes and variants, supporting personalized aortic surveillance and clinical management.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

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Article Medicine, General & Internal

Angiotensin receptor blockers and β blockers in Marfan syndrome: an individual patient data meta-analysis of randomised trials

Alex Pitcher et al.

Summary: In patients with Marfan syndrome, ARBs reduce the rate of increase in the aortic root Z score, including among those taking beta blockers. The effects of beta blockers are similar to those of ARBs. Combination therapy with ARBs and beta blockers provides a more significant reduction in the rate of aortic enlargement than either treatment alone.

LANCET (2022)

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Article Cardiac & Cardiovascular Systems

Outcomes after endovascular versus open thoracoabdominal aortic aneurysm repair: A population-based study

Rodolfo Rocha et al.

Summary: In comparing early and late outcomes of endovascular versus open thoracoabdominal aortic aneurysm repair, it was found that endovascular repair had better early outcomes but higher rates of secondary procedures after discharge when compared to open repair. Long-term survival rates were low and independent of the repair technique used.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2021)

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Article Rehabilitation

Physical exercise for people with hereditable thoracic aortic disease. A study of patient perspectives

Gry Velvin et al.

Summary: The study explored the perspectives of patients with Hereditable Thoracic Aortic Disease on physical exercise, revealing a dilemma between health and risk for these individuals. Inconsistent professional advice and fear of exercise may contribute to sedentary lifestyle. Individualized adapted rehabilitation programs are crucial for encouraging exercise in these patient groups.

DISABILITY AND REHABILITATION (2021)

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Article Surgery

Society for Vascular Surgery clinical practice guidelines of thoracic endovascular aortic repair for descending thoracic aortic aneurysms

Gilbert R. Upchurch et al.

Summary: Thoracic aortic diseases, including descending thoracic aorta disease, are significant causes of death in the United States. TEVAR has largely replaced open repair due to lower morbidity and mortality, but more comparative effectiveness research is needed.

JOURNAL OF VASCULAR SURGERY (2021)

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Article Genetics & Heredity

Genotype FBN1/phenotype relationship in a cohort of patients with Marfan syndrome

Amparo Hernandiz et al.

Summary: Marfan syndrome is a systemic connective tissue disorder caused by mutations in the FBN1 gene, with cardiovascular involvement as the leading cause of mortality. Patients with different genotypes show distinct types of manifestations and age characteristics. Male patients are more likely to have aortic involvement, while patients with specific mutations are more prone to ectopia lentis.

CLINICAL GENETICS (2021)

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Review Cardiac & Cardiovascular Systems

Thoracic Aortic Aneurysm A Clinical Review

Ethan M. Senser et al.

CARDIOLOGY CLINICS (2021)

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Review Surgery

Management of Descending Thoracic Aortic Diseases: Similarities and Differences Among Cardiovascular Guidelines

Konstantinos Spanos et al.

Summary: This study evaluated similarities and differences among the guidelines of current cardiovascular societies for the management of thoracic aortic diseases, analyzing controversial topics and treatment approaches. Significant overlap and agreement were found among the 5 societies regarding the management of thoracic aortic diseases, with TEVAR established as the treatment of choice, especially in dissection and aneurysm management. However, further robust evidence is still needed in many aspects of the management of thoracic aortic pathologies.

JOURNAL OF ENDOVASCULAR THERAPY (2021)

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Article Cardiac & Cardiovascular Systems

Surveillance Imaging Following Acute Type A Aortic Dissection

Kevin R. An et al.

Summary: This study found poor adherence to guideline-directed imaging surveillance following ATAAD repair, while long-term mortality and reinterventions rates remained high. Further research is needed to determine if guidelines should be modified.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2021)

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Article Genetics & Heredity

Clinical relevance of genotype-phenotype correlations beyond vascular events in a cohort study of 1500 Marfan syndrome patients with FBN1 pathogenic variants

Pauline Arnaud et al.

Summary: This study revealed the existence of FBN1 genotype-phenotype correlations for both aortic and extra-aortic features, which can aid in optimal risk stratification of patients, genetic counseling, and personalized medicine. It also contributes additional data to the overall understanding of the role of fibrillin-1 in various organs.

GENETICS IN MEDICINE (2021)

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Article Cardiac & Cardiovascular Systems

2021 The American Association for Thoracic Surgery expert consensus document: Surgical treatment of acute type A aortic dissection

S. Christopher Malaisrie et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2021)

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Article Cardiac & Cardiovascular Systems

Inherited Thoracic Aortic Disease New Insights and Translational Targets

Alexander J. Fletcher et al.

CIRCULATION (2020)

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Article Cardiac & Cardiovascular Systems

Results of frozen elephant trunk from the international E-vita Open registry

Konstantinos Tsagakis et al.

ANNALS OF CARDIOTHORACIC SURGERY (2020)

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Article Surgery

Impact of center volume on outcomes of surgical repair for type A acute aortic dissections

Vishal Dobaria et al.

SURGERY (2020)

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Review Cardiac & Cardiovascular Systems

Type A Aortic Dissection-Experience Over 5 Decades JACC Historical Breakthroughs in Perspective

Yuanjia Zhu et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Association of Family History With Incidence and Outcomes of Aortic Dissection

Shao-Wei Chen et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Management of Women With Congenital or Inherited Cardiovascular Disease From Pre-Conception Through Pregnancy and Postpartum JACC Focus Seminar 2/5

Kathryn J. Lindley et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

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Review Cardiac & Cardiovascular Systems

The Role of Thoracic Endovascular Repair in Chronic Type B Aortic Dissection

Christopher R. Burke et al.

SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY (2020)

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Article Cardiac & Cardiovascular Systems

Current options and recommendations for the treatment of thoracic aortic pathologies involving the aortic arch: an expert consensus document of the European Association for Cardio-Thoracic surgery (EACTS) and the European Society for Vascular Surgery (ESVS)

Martin Czerny et al.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2019)

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Article Cardiac & Cardiovascular Systems

Open and Endovascular Management of Aortic Aneurysms

Nicholas J. Swerdlow et al.

CIRCULATION RESEARCH (2019)

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Review Cardiac & Cardiovascular Systems

Update on Clinical Trials of Losartan With and Without β-Blockers to Block Aneurysm Growth in Patients With Marfan Syndrome A Review

Marion A. Hofmann Bowman et al.

JAMA CARDIOLOGY (2019)

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Review Engineering, Biomedical

Biomechanics of aortic wall failure with a focus on dissection and aneurysm: A review

Selda Sherifova et al.

ACTA BIOMATERIALIA (2019)

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Article Cardiac & Cardiovascular Systems

Volume-Outcome Relationships in Surgical and Endovascular Repair of Aortic Dissection

Alexander A. Brescia et al.

ANNALS OF THORACIC SURGERY (2019)

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Article Cardiac & Cardiovascular Systems

Managing patients with acute type A aortic dissection and mesenteric malperfusion syndrome: A 20-year experience

Bo Yang et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2019)

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Article Cardiac & Cardiovascular Systems

Perioperative Risk Profiles and Volume-Outcome Relationships in Proximal Thoracic Aortic Surgery

Makoto Mori et al.

ANNALS OF THORACIC SURGERY (2018)

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Article Cardiac & Cardiovascular Systems

Expert consensus recommendations on the cardiogenetic care for patients with thoracic aortic disease and their first-degree relatives

Judith M. A. Verhagen et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2018)

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Article Surgery

The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm

Elliot L. Chaikof et al.

JOURNAL OF VASCULAR SURGERY (2018)

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Article Radiology, Nuclear Medicine & Medical Imaging

Cardiovascular Manifestations and Complications of Loeys-Dietz Syndrome: CT and MR Imaging Findings

William W. Loughborough et al.

RADIOGRAPHICS (2018)

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Article Medicine, General & Internal

Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study

Bjorn Pasternak et al.

BMJ-BRITISH MEDICAL JOURNAL (2018)

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Article Medicine, General & Internal

Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study

Bjorn Pasternak et al.

BMJ-BRITISH MEDICAL JOURNAL (2018)

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Article Cardiac & Cardiovascular Systems

Insights From the International Registry of Acute Aortic Dissection A 20-Year Experience of Collaborative Clinical Research

Arturo Evangelista et al.

CIRCULATION (2018)

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Article Cardiac & Cardiovascular Systems

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

Vera Regitz-Zagrosek et al.

EUROPEAN HEART JOURNAL (2018)

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Review Cardiac & Cardiovascular Systems

Aetiology and management of hereditary aortopathy

Aline Verstraeten et al.

NATURE REVIEWS CARDIOLOGY (2017)

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Impact of Discordant Views in the Management of Descending Thoracic Aortic Aneurysm

Peter Chiu et al.

SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY (2017)

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Article Cardiac & Cardiovascular Systems

Pregnancy and Marfan syndrome

Sorel Goland et al.

ANNALS OF CARDIOTHORACIC SURGERY (2017)

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Article Emergency Medicine

Thoracic Aortic Syndromes

Reuben J. Strayer

EMERGENCY MEDICINE CLINICS OF NORTH AMERICA (2017)

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Editorial Material Cardiac & Cardiovascular Systems

Genetic Testing in Thoracic Aortic Diseased-When, Why, and How?

Sarah C. Bowdin et al.

CANADIAN JOURNAL OF CARDIOLOGY (2016)

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Article Cardiac & Cardiovascular Systems

Canadian Cardiovascular Society/Canadian Society of Cardiac Surgeons/Canadian Society for Vascular Surgery Joint Position Statement on Open and Endovascular Surgery for Thoracic Aortic Disease

Jehangir J. Appoo et al.

CANADIAN JOURNAL OF CARDIOLOGY (2016)

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Review Cardiac & Cardiovascular Systems

Screening Children for Familial Aortopathies: Tread With Caution

Julie Richer et al.

CANADIAN JOURNAL OF CARDIOLOGY (2016)

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Article Cardiac & Cardiovascular Systems

Multidisciplinary Aortopathy Clinics Should Now Be the Standard of Care in Canada

Timothy J. Bradley et al.

CANADIAN JOURNAL OF CARDIOLOGY (2016)

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Review Cardiac & Cardiovascular Systems

Pregnancy and Thoracic Aortic Disease: Managing the Risks

Shaynah Wanga et al.

CANADIAN JOURNAL OF CARDIOLOGY (2016)

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Article Medicine, General & Internal

Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone

Chien-Chang Lee et al.

JAMA INTERNAL MEDICINE (2015)

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Article Cardiac & Cardiovascular Systems

Canadian Cardiovascular Society Position Statement on the Management of Thoracic Aortic Disease

Munir Boodhwani et al.

CANADIAN JOURNAL OF CARDIOLOGY (2014)

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Editorial Material Cardiac & Cardiovascular Systems

Activity Recommendations for Postaortic Dissection Patients

Ashish Chaddha et al.

CIRCULATION (2014)

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Editorial Material Surgery

Editor's Choice - Treatment Decisions for Descending Thoracic Aneurysm: Preferences for Thoracic Endovascular Aneurysm Repair or Surveillance in a Discrete Choice Experiment

N. Rudarakanchana et al.

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY (2014)

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Article Genetics & Heredity

Loeys-Dietz syndrome: a primer for diagnosis and management

Gretchen MacCarrick et al.

GENETICS IN MEDICINE (2014)

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Article Cardiac & Cardiovascular Systems

Outcomes of Acute Type A Dissection Repair Before and After Implementation of a Multidisciplinary Thoracic Aortic Surgery Program

Nicholas D. Andersen et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

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Article Cardiac & Cardiovascular Systems

Endovascular Repair of Type B Aortic Dissection Long-term Results of the Randomized Investigation of Stent Grafts in Aortic Dissection Trial

Christoph A. Nienaber et al.

CIRCULATION-CARDIOVASCULAR INTERVENTIONS (2013)

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Review Health Care Sciences & Services

Systematic review and meta-analysis of the growth and rupture rates of small abdominal aortic aneurysms: implications for surveillance intervals and their cost-effectiveness

S. G. Thompson et al.

HEALTH TECHNOLOGY ASSESSMENT (2013)

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Article Cardiac & Cardiovascular Systems

Echocardiography in the emergency assessment of acute aortic syndromes

E. Louise Meredith et al.

EUROPEAN JOURNAL OF ECHOCARDIOGRAPHY (2009)

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Article Cardiac & Cardiovascular Systems

Effect of beta-blockade on ascending aortic dilatation in children with the Marfan syndrome

Magalie Ladouceur et al.

AMERICAN JOURNAL OF CARDIOLOGY (2007)

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Review Medicine, General & Internal

Diagnostic accuracy of transesophageal echocardiography, helical computed tomography, and magnetic resonance imaging for suspected thoracic aortic dissection - Systematic review and meta-analysis

Toshiya Shiga et al.

ARCHIVES OF INTERNAL MEDICINE (2006)

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Article Cardiac & Cardiovascular Systems

Task force 8: Classification of sports

JH Mitchell et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)

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Article Cardiac & Cardiovascular Systems

Abdominal aortic aneurysm expansion - Risk factors and time intervals for surveillance

AR Brady et al.

CIRCULATION (2004)

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The Aortic Team Model and Collaborative Decision Pathways for the Management of Complex Aortic Disease: Clinical Practice Update From the Canadian Cardiovascular Society/Canadian Society of Cardiac Surgeons/Canadian Society for Vascular Surgery/Canadian Association for Interventional Radiology

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