Related references
Note: Only part of the references are listed.Machine Learning C–N Couplings: Obstacles for a General-Purpose Reaction Yield Prediction
Martin Fitzner et al.
ACS Omega (2023)
A Brief Introduction to Chemical Reaction Optimization
Connor J. Taylor et al.
CHEMICAL REVIEWS (2023)
Open-Source Chromatographic Data Analysis for Reaction Optimization and Screening
Christian P. Haas et al.
ACS CENTRAL SCIENCE (2023)
Development of a High-Throughput Kinetics Protocol and Application to an Aza-Michael Reaction
Xiao Li et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2022)
Leveraging High-Throughput Experimentation to Drive Pharmaceutical Route Invention: A Four-Step Commercial Synthesis of Branebrutinib (BMS-986195)
Jason M. Stevens et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2022)
Machine Learning May Sometimes Simply Capture LiteraturePopularity Trends: A Case Study of Heterocyclic Suzuki-MiyauraCoupling
Wiktor Beker et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)
Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation
Charles E. Hendrick et al.
ACS MEDICINAL CHEMISTRY LETTERS (2022)
A Validated Pool and Split Approach to Screening and Optimization of Copper-Catalyzed C-N Cross-Coupling Reactions
Raphael R. Steimbach et al.
JOURNAL OF ORGANIC CHEMISTRY (2021)
A Perspective on the Analytical Challenges Encountered in High-Throughput Experimentation
Rachel Grainger et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2021)
The Open Reaction Database
Steven M. Kearnes et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)
Direct Arylation of Azoles Enabled by Pd/Cu Dual Catalysis
Tiffany Piou et al.
ORGANIC LETTERS (2021)
Ultrahigh-Throughput Experimentation for Information-Rich Chemical Synthesis
Babak Mahjour et al.
ACCOUNTS OF CHEMICAL RESEARCH (2021)
Predicting Reaction Yields via Supervised Learning
Andrzej M. Zuranski et al.
ACCOUNTS OF CHEMICAL RESEARCH (2021)
A direct-to-biology high-throughput chemistry approach to reactive fragment screening
Ross P. Thomas et al.
CHEMICAL SCIENCE (2021)
Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers
Kai Gao et al.
RSC MEDICINAL CHEMISTRY (2021)
Automated, Accelerated Nanoscale Synthesis of Iminopyrrolidines
Angelina Osipyan et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
High-Throughput Experimentation and Continuous Flow Evaluation of Nucleophilic Aromatic Substitution Reactions
Zinia Jaman et al.
ACS COMBINATORIAL SCIENCE (2020)
Use of High-Throughput Tools for Telescoped Continuous Flow Synthesis of an Alkynylnaphthyridine Anticancer Agent, HSN608
Shruti A. Biyani et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2020)
The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future
Steven M. Mennen et al.
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2019)
Biaryl monophosphine ligands in palladium-catalyzed C-N coupling: An updated User's guide
Bryan T. Ingoglia et al.
TETRAHEDRON (2019)
Reaction Conditions for the Regiodivergent Direct Arylations at C2-or C5-Positions of Oxazoles using Phosphine-Free Palladium Catalysts
Xinzhe Shi et al.
ADVANCED SYNTHESIS & CATALYSIS (2019)
HappyTools: A software for high-throughput HPLC data processing and quantitation
Bas Cornelis Jansen et al.
PLOS ONE (2018)
Mapping the dark space of chemical reactions with extended nanomole synthesis and MALDI-TOF MS
Shishi Lin et al.
SCIENCE (2018)
Synthesis of N-heterocyclic carbene-PdCl-[(2-Pyridyl)alkyl carboxylate] complexes and their catalytic activities towards arylation of (benzo)oxazoles with aryl bromides
Wei Chen et al.
JOURNAL OF ORGANOMETALLIC CHEMISTRY (2018)
Nanoscale synthesis and affinity ranking
Nathan J. Gesmundo et al.
NATURE (2018)
Microscale High-Throughput Experimentation as an Enabling Technology in Drug Discovery: Application in the Discovery of (Piperidinyl)pyridinyl-1H-benzimidazole Diacylglycerol Acyltransferase 1 Inhibitors
Tim Cernak et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Practical High-Throughput Experimentation for Chemists
Michael Shevlin
ACS MEDICINAL CHEMISTRY LETTERS (2017)
The Evolution of Chemical High-Throughput Experimentation To Address Challenging Problems in Pharmaceutical Synthesis
Shane W. Krska et al.
ACCOUNTS OF CHEMICAL RESEARCH (2017)
Nanomole-scale high-throughput chemistry for the synthesis of complex molecules
Alexander Buitrago Santanilla et al.
SCIENCE (2015)
Direct C-H Bond Arylation of (Benzo)oxazoles with Aryl Chlorides Catalyzed by N-Heterocyclic Carbene-Palladium(II)-1-Methylimidazole Complex
Xiao-Bao Shen et al.
ORGANIC LETTERS (2014)
Mechanism Selection for Regiocontrol in Base-Assisted, Palladium-Catalysed Direct C-H Coupling with Halides: First Approach for Oxazole- and Thiazole-4-Carboxylates
Laure Theveau et al.
CHEMISTRY-A EUROPEAN JOURNAL (2011)
Carbonates: eco-friendly solvents for palladium-catalysed direct arylation of heteroaromatics
Jia Jia Dong et al.
GREEN CHEMISTRY (2010)
A Highly Efficient Palladium/Copper Cocatalytic System for Direct Arylation of Heteroarenes: An Unexpected Effect of Cu(Xantphos)I
Jinkun Huang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Highly Regioselective Palladium-Catalyzed Direct Arylation of Oxazole at C-2 or C-5 with Aryl Bromides, Chlorides, and Triflates
Neil A. Strotman et al.
ORGANIC LETTERS (2010)
MISER chromatography (multiple injections in a single experimental run): the chromatogram is the graph
Christopher J. Welch et al.
TETRAHEDRON-ASYMMETRY (2010)
Palladium-catalyzed direct (hetero)arylation of ethyl oxazole-4-carboxylate: An efficient access to (hetero)aryloxazoles
Cecile Verrier et al.
JOURNAL OF ORGANIC CHEMISTRY (2008)