Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 169, Issue -, Pages -Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2023.115870
Keywords
Cell therapy; Regeneration medicine; Coronary heart disease; Cell delivery approaches
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This review provides an update on the techniques and clinical studies of cell treatment for coronary heart disease (CHD), with a focus on the emerging efficacy of stem cell treatment. It specifically examines and comments on current breakthroughs in cell treatment for CHD, including the most effective types of cells, transport modalities, engineering, and biochemical approaches used in this context. It aims to help researchers distill this information and design future studies to overcome the challenges faced by this revolutionary approach for CHD.
Cell therapy is an important topic in the field of regeneration medicine that is gaining attention within the scientific community. However, its potential for treatment in coronary heart disease (CHD) has yet to be established. Several various strategies, types of cells, routes of distribution, and supporting procedures have been tried and refined to trigger heart rejuvenation in CHD. However, only a few of them result in a real considerable promise for clinical usage. In this review, we give an update on techniques and clinical studies of cell treatment as used to cure CHD that are now ongoing or have been completed in the previous five years. We also highlight the emerging efficacy of stem cell treatment for CHD. We specifically examine and comment on current breakthroughs in cell treatment applied to CHD, including the most effective types of cells, transport modalities, engineering, and biochemical approaches used in this context. We believe the current review will be helpful for the researcher to distill this information and design future studies to overcome the challenges faced by this revolutionary approach for CHD.
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