Journal
JOURNAL OF NON-CRYSTALLINE SOLIDS
Volume 624, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.jnoncrysol.2023.122708
Keywords
Bioactive glass; CaF 2; Bioactivity; Hydroxyapatite; Fluorapatite; Biomaterial
Ask authors/readers for more resources
This study evaluated the influence of CaF2 addition on the bioactivity of the samples. The results showed that the samples exhibited good bioactivity and cytocompatibility, making them suitable for biomedical applications.
This work aimed to evaluate the influence of CaF2 addition in the bioactivity of the samples. The system 60B2O34P2O5-18Na2O-xCaF2-(18-xCaO), with x= 0, 5 and 10 wt% was synthetized by melt-quenching method. The in vitro bioactivity of the glasses was investigated by X-ray diffractogram (XRD), Raman, Fourier transform infrared spectroscopy (FTIR) and pH after immersion in SBF solution during 28 days. Results of pH presented an increase after 24 hours of soaking in SBF, which contributes to the dissolution of the external layer of the glass and precipitation of apatite. Hydroxyapatite and fluorapatite formation was confirmed by XRD patterns, Raman and FTIR spectra, confirming the bioactivity of the samples. Cytotoxicity tests were performed on osteoblastic cells. All the samples presented cytotoxicity smaller than 10%, and induced the osteoblast proliferation, indicating a good cytocompatibility and good cell viability. Therefore, the glasses have potential to be applied in biomedical applications, such as odontology and tissue engineering.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available