Related references
Note: Only part of the references are listed.Antibody-drug conjugates come of age in oncology
Charles Dumontet et al.
NATURE REVIEWS DRUG DISCOVERY (2023)
Carbon-Centered Radicals in Protein Manipulation
Benjamin G. Davis et al.
ACS CENTRAL SCIENCE (2023)
Pd(II)-Mediated C-H Activation for Cysteine Bioconjugation
James A. R. Tilden et al.
CHEMISTRY-A EUROPEAN JOURNAL (2022)
Flavin Metallaphotoredox Catalysis: Synergistic Synthesis in Water
Maheshwerreddy Chilamari et al.
ACS CATALYSIS (2022)
Organometallic S-arylation Reagents for Rapid PEGylation of Biomolecules
Hayden R. Montgomery et al.
BIOCONJUGATE CHEMISTRY (2022)
Dual-Boronic Acid Reagents That Combine Dynamic and Covalent Bioconjugation
Michael J. Swierczynski et al.
BIOCONJUGATE CHEMISTRY (2022)
Antibody drug conjugate: the biological missile for targeted cancer therapy
Zhiwen Fu et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)
Bioorthogonal Chemistry and Its Applications
Robert E. Bird et al.
BIOCONJUGATE CHEMISTRY (2021)
Photoredox Nickel-Catalyzed C-S Cross-Coupling: Mechanism, Kinetics, and Generalization
Yangzhong Qin et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)
Protein oxidation-Formation mechanisms, detection and relevance as biomarkers in human diseases
Richard Kehm et al.
REDOX BIOLOGY (2021)
Oligonucleotide Bioconjugation with Bifunctional Palladium Reagents
Muhammad Jbara et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
The Chemistry Behind ADCs
Vesela Kostova et al.
PHARMACEUTICALS (2021)
The Expanding Role of Chemistry in Optimizing Proteins for Human Health Applications
Bart Roman
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Boronic Acid Pairs for Sequential Bioconjugation
Mary K. Miller et al.
ORGANIC LETTERS (2021)
Site-selective modification strategies in antibody-drug conjugates
Stephen J. Walsh et al.
CHEMICAL SOCIETY REVIEWS (2021)
Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer
Shanu Modi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
New Chemical Modalities and Strategic Thinking in Early Drug Discovery
Maria-Jesus Blanco et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Transition-Metal-Mediated Modification of Biomolecules
Jessica Rodriguez et al.
CHEMISTRY-A EUROPEAN JOURNAL (2020)
Mechanistic Analysis of Metallaphotoredox C-N Coupling: Photocatalysis Initiates and Perpetuates Ni(I)/Ni(III) Coupling Activity
Nicholas A. Till et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
One-Step Protein-Polymer Conjugates from Boronic-Acid-Functionalized Polymers
Michael J. Swierczynski et al.
BIOCONJUGATE CHEMISTRY (2020)
Radiopharmaceutical therapy in cancer: clinical advances and challenges
George Sgouros et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
Considerations for setting occupational exposure limits for novel pharmaceutical modalities
Jessica C. Graham et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2020)
Bioconjugation with Maleimides: A Useful Tool for Chemical Biology
Joao M. J. M. Ravasco et al.
CHEMISTRY-A EUROPEAN JOURNAL (2019)
Glycoengineering of Antibodies for Modulating Functions
Lai-Xi Wang et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 88 (2019)
Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis
James P. Phelan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
Native Chemical Ligation and Extended Methods: Mechanisms, Catalysis, Scope, and Limitations
Vangelis Agouridas et al.
CHEMICAL REVIEWS (2019)
Concepts of Catalysis in Site-Selective Protein Modifications
Patrick G. Isenegger et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
On-DNA Decarboxylative Arylation: Merging Photoredox with Nickel Catalysis in Water
Dominik K. Kolmel et al.
ACS COMBINATORIAL SCIENCE (2019)
Arylation Chemistry for Bioconjugation
Chi Zhang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)
Elucidation of a Redox-Mediated Reaction Cycle for Nickel-Catalyzed Cross Coupling
Rui Sun et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
Rapid nickel(ii)-promoted cysteine S-arylation with arylboronic acids
Kengo Hanaya et al.
CHEMICAL COMMUNICATIONS (2019)
The impact of structural biology in medicine illustrated with four case studies
Tiancen Hu et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2018)
Tuning the Diels-Alder Reaction for Bioconjugation to Maleimide Drug-Linkers
Andre H. St Amant et al.
BIOCONJUGATE CHEMISTRY (2018)
Organometallic Gold(III) Reagents for Cysteine Arylation
Marco S. Messina et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
Scalable thioarylation of unprotected peptides and biomolecules under Ni/photoredox catalysis
Brandon A. Vara et al.
CHEMICAL SCIENCE (2018)
Site-Specific Antibody Drug Conjugates Using Streamlined Expressed Protein Ligation
Silvia Frutos et al.
BIOCONJUGATE CHEMISTRY (2018)
Visible-Light-Mediated Selective Arylation of Cysteine in Batch and Flow
Cecilia Bottecchia et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Base-Free Photoredox/Nickel Dual-Catalytic Cross-Coupling of Ammonium Alkylsilicates
Matthieu Jouffroy et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Site-selective protein-modification chemistry for basic biology and drug development
Nikolaus Krall et al.
NATURE CHEMISTRY (2016)
Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature
Riyadh Ahmed Atto Al-Shuaeeb et al.
CHEMISTRY-A EUROPEAN JOURNAL (2016)
Selective Metal-Site-Guided Arylation of Proteins
Jens Willwacher et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Development of Novel Quaternary Ammonium Linkers for Antibody-Drug Conjugates
Patrick J. Burke et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates
Leanna R. Staben et al.
NATURE CHEMISTRY (2016)
Thioetherification via Photoredox/Nickel Dual Catalysis
Matthieu Jouffroy et al.
ORGANIC LETTERS (2016)
Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody-Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers
Thomas M. Cardillo et al.
BIOCONJUGATE CHEMISTRY (2015)
Organometallic palladium reagents for cysteine bioconjugation
Ekaterina V. Vinogradova et al.
NATURE (2015)
Cyclometalated gold(III) complexes for chemoselective cysteine modification via ligand controlled C-S bond-forming reductive elimination
Karen Ka-Yan Kung et al.
CHEMICAL COMMUNICATIONS (2014)
Ado-trastuzumab Emtansine (T-DM1): An Antibody-Drug Conjugate (ADC) for HER2-Positive Breast Cancer
John M. Lambert et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Therapeutic Protein-Polymer Conjugates: Advancing Beyond PEGylation
Emma M. Pelegri-O'Day et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
The ubiquitous DOTA and its derivatives: the impact of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid on biomedical imaging
Graeme J. Stasiuk et al.
CHEMICAL COMMUNICATIONS (2013)
Demonstration of the Innate Electrophilicity of 4-(3(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor
Heather Eng et al.
DRUG METABOLISM AND DISPOSITION (2013)
Bioactivation of 2-(Alkylthio)-1,3,4-Thiadiazoles and 2-(Alkylthio)-1, 3-Benzothiazoles
Yanou Yang et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2012)
A novel pathway for maytansinoid release from thioether linked antibody-drug conjugates (ADCs) under oxidative conditions
Nathan Fishkin et al.
CHEMICAL COMMUNICATIONS (2011)
Contribution of linker stability to the activities of anticancer immunoconjugates
Stephen C. Alley et al.
BIOCONJUGATE CHEMISTRY (2008)
Phase 1 trial of the antiangiogenic peptide ATN-161 (Ac-PHSCN-NH2), a beta integrin antagonist, in patients with solid tumours
M. E. Cianfrocca et al.
BRITISH JOURNAL OF CANCER (2006)
Repair of oxidative DNA damage by amino acids
JR Milligan et al.
NUCLEIC ACIDS RESEARCH (2003)