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CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2010)
Tanshinone IIA modulates pulmonary vascular response to agonist and hypoxia primarily via inhibiting Ca2+ influx and release in normal and hypoxic pulmonary hypertension rats
Jing Wang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
Antioxidant and mitochondrial protective effects of oxidized metabolites of oltipraz
Song Hwa Choi et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2010)
Rosiglitazone attenuates hypoxia-induced pulmonary arterial hypertension in rats
Eun Kyung Kim et al.
RESPIROLOGY (2010)
Treatment with the Kv7 potassium channel activator flupirtine is beneficial in two independent mouse models of pulmonary hypertension
I. Morecroft et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Sulfasalazine induces haem oxygenase-1 via ROS-dependent Nrf2 signalling, leading to control of neointimal hyperplasia
Ju-Young Kim et al.
CARDIOVASCULAR RESEARCH (2009)
Guidelines for the diagnosis and treatment of pulmonary hypertension
Nazzareno Galie et al.
EUROPEAN HEART JOURNAL (2009)
The science of endothelin-1 and endothelin receptor antagonists in the management of pulmonary arterial hypertension: current understanding and future studies
N. J. Davie et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2009)
Resveratrol Prevents Monocrotaline-Induced Pulmonary Hypertension in Rats
Anna Csiszar et al.
HYPERTENSION (2009)
C-Reactive Protein A New Predictor of Adverse Outcome in Pulmonary Arterial Hypertension
Rozenn Quarck et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)
Impaired Voltage Gated Potassium Channel Responses in a Fetal Lamb Model of Persistent Pulmonary Hypertension of the Newborn
Girija G. Konduri et al.
PEDIATRIC RESEARCH (2009)
Pathology of Pulmonary Arterial Hypertension
Rubin M. Tuder
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2009)
Pulmonary hypertension
Gorev Grubu Uyeleri et al.
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY (2009)
Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K+ channel expression in pulmonary arterial myocytes
E. Miles Whitman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Thrombin-mediated increases in cytosolic [Ca2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells
Richard S. Sacks et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension
Kathryn N. Farrow et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling
Eva Nozik-Grayck et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Gene transfer of extracellular superoxide dismutase ameliorates pulmonary hypertension in rats
Fumihiko Kamezaki et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)
Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: pharmacotherapeutic implications
E. D. Burg et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Rosiglitazone but not losartan prevents Nrf-2 dependent CD36 gene expression up-regulation in an in vivo atherosclerosis model
Y. Hernandez-Trujillo et al.
CARDIOVASCULAR DIABETOLOGY (2008)
PDE5 inhibitors for cystic fibrosis: can they also enhance chloride transport?
Sabina A. Antoniu
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2008)
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
Sebastien Bonnet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Potassium channel diversity in the pulmonary arteries and pulmonary veins: Implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension
Sebastien Bonnet et al.
PHARMACOLOGY & THERAPEUTICS (2007)
Nrf2 is involved in the effect of tanshinone IIA on intracellular redox status in human aortic smooth muscle cells
Hong-Sheng Zhang et al.
BIOCHEMICAL PHARMACOLOGY (2007)
Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo
Anna-Liisa Levonen et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling
Joseph T. Crossno et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Impact of TASK-1 in human pulmonary artery smooth muscle cells
A Olschewski et al.
CIRCULATION RESEARCH (2006)
Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase
ML Sentman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mechanistic studies of the Nrf2-Keap1 signaling pathway
Donna D. Zhang
DRUG METABOLISM REVIEWS (2006)
Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: Protection against reactive oxygen and nitrogen species-induced cell injury
H Zhu et al.
FEBS LETTERS (2005)
Endothelial dysfunction in pulmonary hypertension
R Budhiraja et al.
CIRCULATION (2004)
The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: Oxidative stress sensing by a Cul3-Keap1 ligase
SB Cullinan et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate for proteasomal degradation of Nrf2
A Kobayashi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Coronary-artery revascularization before elective major vascular surgery
EO McFalls et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
K Itoh et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction -: Role of protein kinase Cζ
A Cogolludo et al.
CIRCULATION RESEARCH (2003)
Curcurnin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
E Balogun et al.
BIOCHEMICAL JOURNAL (2003)
In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction chronically hypoxic rats
ZI Pozeg et al.
CIRCULATION (2003)
Herne oxygenase-1 reduces murine monocrotaline-induced pulmonary inflammatory responses and resultant right ventricular overload
J Goto et al.
ANTIOXIDANTS & REDOX SIGNALING (2002)
Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor
C Atkinson et al.
CIRCULATION (2002)
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats - Role of increased expression and activity of voltage-gated potassium channels
ED Michelakis et al.
CIRCULATION (2002)
Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia
T Minamino et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
TASK-5, a new member of the tandem-pore K+ channel family
D Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein
JY Chan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2000)
Primary pulmonary hypertension - A vascular biology and translational research work in progress
S Archer et al.
CIRCULATION (2000)
Chronic intrauterine pulmonary hypertension decreases calcium-sensitive potassium channel mRNA expression
DN Cornfield et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2000)
The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin
JD Hayes et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2000)