Related references
Note: Only part of the references are listed.PFKFB3-Mediated Glycolysis Boosts Fibroblast Activation and Subsequent Kidney Fibrosis
Qiuhua Yang et al.
CELLS (2023)
Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD-fed mice
Qiuhua Yang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2022)
Myeloid Piezo1 Deletion Protects Renal Fibrosis by Restraining Macrophage Infiltration and Activation
Yu He et al.
HYPERTENSION (2022)
Aerobic glycolysis imaging of epileptic foci during the inter-ictal period
Miao Zhang et al.
EBIOMEDICINE (2022)
Gene-dosage effect of Pfkfb3 on monocyte/macrophage biology in atherosclerosis
Shuai Guo et al.
BRITISH JOURNAL OF PHARMACOLOGY (2022)
Suppression of myeloid PFKFB3-driven glycolysis protects mice from choroidal neovascularization
Zhiping Liu et al.
BRITISH JOURNAL OF PHARMACOLOGY (2022)
Targeting glycolysis in non-small cell lung cancer: Promises and challenges
Jia-Qi Xu et al.
FRONTIERS IN PHARMACOLOGY (2022)
The significance of glycolysis in tumor progression and its relationship with the tumor microenvironment
Daoying Zhou et al.
FRONTIERS IN PHARMACOLOGY (2022)
Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
Shihui Xu et al.
EBIOMEDICINE (2022)
The role of the macrophage-to-myofibroblast transition in renal fibrosis
Jia Wei et al.
FRONTIERS IN IMMUNOLOGY (2022)
Jmjd3/IRF4 axis aggravates myeloid fibroblast activation and m2 macrophage to myofibroblast transition in renal fibrosis
Hua Liang et al.
FRONTIERS IN IMMUNOLOGY (2022)
ATIC-Associated De Novo Purine Synthesis Is Critically Involved in Proliferative Arterial Disease
Qian Ma et al.
CIRCULATION (2022)
Mice with a specific deficiency of Pfkfb3 in myeloid cells are protected from hypoxia-induced pulmonary hypertension
Lina Wang et al.
BRITISH JOURNAL OF PHARMACOLOGY (2021)
Prkaa1 Metabolically Regulates Monocyte/Macrophage Recruitment and Viability in Diet-Induced Murine Metabolic Disorders
Qiuhua Yang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Deletion of Myeloid Interferon Regulatory Factor 4 (Irf4) in Mouse Model Protects against Kidney Fibrosis after Ischemic Injury by Decreased Macrophage Recruitment and Activation
Kensuke Sasaki et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)
Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions
Kenichiro Miyauchi et al.
EBIOMEDICINE (2021)
Glucose Metabolism in Acute Kidney Injury and Kidney Repair
Lu Wen et al.
FRONTIERS IN MEDICINE (2021)
Metabolic Reprogramming and Renal Fibrosis
Xiaoyu Zhu et al.
FRONTIERS IN MEDICINE (2021)
Disruption of endothelial Pfkfb3 ameliorates diet-induced murine insulin resistance
Qiuhua Yang et al.
JOURNAL OF ENDOCRINOLOGY (2021)
Decoding myofibroblast origins in human kidney fibrosis
Christoph Kuppe et al.
NATURE (2021)
Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage-myofibroblast transition
Patrick Ming-Kuen Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice
Wei Tao et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche
Zhiping Liu et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease
Bryan R. Conway et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)
Inhibition of Fatty Acid-Binding Protein 4 Attenuated Kidney Fibrosis by Mediating Macrophage-to-Myofibroblast Transition
Yanhuan Feng et al.
FRONTIERS IN IMMUNOLOGY (2020)
Macrophages: versatile players in renal inflammation and fibrosis
Patrick Ming-Kuen Tang et al.
NATURE REVIEWS NEPHROLOGY (2019)
KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis
Yi Wen et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2019)
PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension
Yapeng Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Glycolysis inhibitors suppress renal interstitial fibrosis via divergent effects on fibroblasts and tubular cells
Qingqing Wei et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2019)
Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis
Divya Bhatia et al.
JCI INSIGHT (2019)
PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis
Qiuhua Yang et al.
NATURE COMMUNICATIONS (2018)
Macrophages in diabetic nephropathy in patients with type 2 diabetes
Celine Q. F. Klessens et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2017)
Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury
Ying-Ying Wang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
M1 macrophage triggered by Mincle leads to a deterioration of acute kidney injury
Tsuyoshi Inoue
KIDNEY INTERNATIONAL (2017)
Metabolism Supports Macrophage Activation
P. Kent Langston et al.
FRONTIERS IN IMMUNOLOGY (2017)
Inhibiting aerobic glycolysis suppresses renal interstitial fibroblast activation and renal fibrosis
Hao Ding et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2017)
Tissue macrophages: heterogeneity and functions
Siamon Gordon et al.
BMC BIOLOGY (2017)
Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis
Xiao-Ming Meng et al.
CELL DEATH & DISEASE (2016)
Glycolytic Reprogramming in Myofibroblast Differentiation and Lung Fibrosis
Na Xie et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2015)
Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3
Scott Boyd et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Origin of myofibroblasts and cellular events triggering fibrosis
Matthias Mack et al.
KIDNEY INTERNATIONAL (2015)
Fibrosis - A Common Pathway to Organ Injury and Failure
Don C. Rockey et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Macrophages in Kidney Injury, Inflammation, and Fibrosis
Qi Cao et al.
PHYSIOLOGY (2015)
Macrophage-mediated injury and repair after ischemic kidney injury
Sarah C. Huen et al.
PEDIATRIC NEPHROLOGY (2015)
The Role of M2 Macrophages in the Progression of Chronic Kidney Disease following Acute Kidney Injury
Myung-Gyu Kim et al.
PLOS ONE (2015)
Endothelial PFKFB3 Plays a Critical Role in Angiogenesis
Yiming Xu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)
Macrophages Regulate Renal Fibrosis Through Modulating TGFβ Superfamily Signaling
Bing Shen et al.
INFLAMMATION (2014)
Macrophages promote renal fibrosis through direct and indirect mechanisms
David J. Nikolic-Paterson et al.
KIDNEY INTERNATIONAL SUPPLEMENTS (2014)
Recruitment and subsequent proliferation of bone marrow-derived cells in the postischemic kidney are important to the progression of fibrosis
Hee-Seong Jang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2014)
Origin and function of myofibroblasts in kidney fibrosis
Valerie S. LeBleu et al.
NATURE MEDICINE (2013)
Role of macrophages in the fibrotic phase of rat crescentic glomerulonephritis
Yingjie Han et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2013)
Macrophage/monocyte depletion by clodronate, but not diphtheria toxin, improves renal ischemia/reperfusion injury in mice
David A. Ferenbach et al.
KIDNEY INTERNATIONAL (2012)
MyD88 Signaling Pathway Is Involved in Renal Fibrosis by Favoring a TH2 Immune Response and Activating Alternative M2 Macrophages
Tarcio Teodoro Braga et al.
MOLECULAR MEDICINE (2012)
Classical Macrophage Activation Up-Regulates Several Matrix Metalloproteinases through Mitogen Activated Protein Kinases and Nuclear Factor-κB
Wei-Chun Huang et al.
PLOS ONE (2012)
Identification of alternatively activated macrophages in new-onset paediatric and adult immunoglobulin A nephropathy: potential role in mesangial matrix expansion
Yohei Ikezumi et al.
HISTOPATHOLOGY (2011)
Inhibition of matrix metalloproteinases reduces ischemia-reperfusion acute kidney injury
Shinobu Kunugi et al.
LABORATORY INVESTIGATION (2011)
Alteration in the phenotype of macrophages in the repair of renal interstitial fibrosis in mice
Taketoshi Kushiyama et al.
NEPHROLOGY (2011)
Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis
Benjamin D. Humphreys et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
CCR2 antagonism improves insulin resistance, lipid metabolism, and diabetic nephropathy in type 2 diabetic mice
Young Sun Kang et al.
KIDNEY INTERNATIONAL (2010)
Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice
A. K. H. Lim et al.
DIABETOLOGIA (2009)
Bone Marrow Ly6Chigh Monocytes Are Selectively Recruited to Injured Kidney and Differentiate into Functionally Distinct Populations
Shuei Liong Lin et al.
JOURNAL OF IMMUNOLOGY (2009)
MCP-1/CCL2: a new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy
G. H. Tesch
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
Elisabeth M. Zeisberg et al.
NATURE MEDICINE (2007)
Bone marrow-derived myofibroblasts contribute to the renal interstitial myofibroblast population and produce procollagen I after ischemia/reperfusion in rats
Martine Broekema et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
The contribution of bone marrow-derived cells to the development of renal interstitial fibrosis
Jinhua Li et al.
STEM CELLS (2007)
Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice
Sandra B. Haudek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice
FY Chow et al.
KIDNEY INTERNATIONAL (2006)
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1
HS Lu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Conditional ablation of macrophages halts progression of crescentic glomerulonephritis
JS Duffield et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Blood monocytes consist of two principal subsets with distinct migratory properties
F Geissmann et al.
IMMUNITY (2003)
Interferon-γ augments acute macrophage-mediated renal injury via a glucocorticoid-sensitive mechanism
Y Ikezumi et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Blockade of macrophage colony-stimulating factor reduces macrophage proliferation and accumulation in renal allograft rejection
MD Jose et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2003)
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
HS Lu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Participation of different macrophage populations and myofibroblastic cells in chronically developed renal interstitial fibrosis after cisplatin-induced renal injury in rats
J Yamate et al.
VETERINARY PATHOLOGY (2002)
Tubules are the major site of M-CSF production in experimental kidney disease: Correlation with local macrophage proliferation
NM Isbel et al.
KIDNEY INTERNATIONAL (2001)
Local macrophage proliferation correlates with increased renal M-CSF expression in human glomerulonephritis
NM Isbel et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2001)