Related references
Note: Only part of the references are listed.Ferroptosis: regulation by competition between NRF2 and BACH1 and propagation of the death signal
Hironari Nishizawa et al.
FEBS JOURNAL (2023)
DNA Alkylation Damage by Nitrosamines and Relevant DNA Repair Pathways
Joerg Fahrer et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Young-onset colorectal cancer
Manon C. W. Spaander et al.
NATURE REVIEWS DISEASE PRIMERS (2023)
Role of ferroptosis in colorectal cancer
Ya-Qi Song et al.
World Journal of Gastrointestinal Oncology (2023)
Therapeutic inhibition of ferroptosis in neurodegenerative disease
Sean K. Ryan et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2023)
New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens-a PARC project
Marc Audebert et al.
FRONTIERS IN TOXICOLOGY (2023)
Hemin enhances radiosensitivity of lung cancer cells through ferroptosis
Waleed Abdelbag Almahi et al.
EXPERIMENTAL CELL RESEARCH (2022)
HIF1A-induced heme oxygenase 1 promotes the survival of decidual stromal cells against excess heme-mediated oxidative stress
Hui-Hui Shen et al.
REPRODUCTION (2022)
Molecular Mechanisms of Iron and Heme Metabolism
Sohini Dutt et al.
ANNUAL REVIEW OF NUTRITION (2022)
Iron and liver cancer: an inseparable connection
Keisuke Hino et al.
FEBS JOURNAL (2022)
Epithelial de-differentiation triggered by co-ordinate epigenetic inactivation of the EHF and CDX1 transcription factors drives colorectal cancer progression
Ian Y. Luk et al.
CELL DEATH AND DIFFERENTIATION (2022)
Hemin mitigates contrast-induced nephropathy by inhibiting ferroptosis via HO-1/Nrf2/GPX4 pathway
Zhao Gao et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2022)
ICAM-1 promotes cancer progression by regulating SRC activity as an adapter protein in colorectal cancer
Eun-Ji Lim et al.
CELL DEATH & DISEASE (2022)
Oxaliplatin induces ferroptosis and oxidative stress in HT29 colorectal cancer cells by inhibiting the Nrf2 signaling pathway
Ben Liu et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2022)
Heme Oxygenase-1: An Anti-Inflammatory Effector in Cardiovascular, Lung, and Related Metabolic Disorders
Stefan W. Ryter
ANTIOXIDANTS (2022)
Heme induces intestinal epithelial cell ferroptosis via mitochondrial dysfunction in transfusion-associated necrotizing enterocolitis
Dan Dang et al.
FASEB JOURNAL (2022)
Role of Heme Oxygenase in Gastrointestinal Epithelial Cells
Reiko Akagi
ANTIOXIDANTS (2022)
One ring to bring them all and in the darkness bind them: The trafficking of heme without deliverers
Ian G. Chambers et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2021)
Mutational drivers of cancer cell migration and invasion
Nikita M. Novikov et al.
BRITISH JOURNAL OF CANCER (2021)
Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
Bo Yan et al.
MOLECULAR CELL (2021)
Heme Oxygenase-1 Deficiency and Oxidative Stress: A Review of 9 Independent Human Cases and Animal Models
Akihiro Yachie
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
The expression and Clinical Significance of miRNA-135a and Bach1 in colorectal cancer
Yang zhi Jiang et al.
INTERNATIONAL SURGERY (2021)
Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation
Stefan W. Ryter
CELLS (2021)
Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo
Nina Seiwert et al.
ARCHIVES OF TOXICOLOGY (2021)
Heme Oxygenase-1 Signaling and Redox Homeostasis in Physiopathological Conditions
Valeria Consoli et al.
BIOMOLECULES (2021)
Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction
Anqi Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2021)
Endothelin-1 as a Mediator of Heme Oxygenase-1-Induced Stemness in Colorectal Cancer: Influence of p53
Sandra Rios-Arrabal et al.
JOURNAL OF PERSONALIZED MEDICINE (2021)
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron
Rashi Singhal et al.
JOURNAL OF CLINICAL INVESTIGATION (2021)
Regulation of inflammation by the antioxidant haem oxygenase 1
Nicole K. Campbell et al.
NATURE REVIEWS IMMUNOLOGY (2021)
Increasing Heme Oxygenase-1-Expressing Macrophages Indicates a Tendency of Poor Prognosis in Advanced Colorectal Cancer
Shingo Kimura et al.
DIGESTION (2020)
Mechanism of colorectal carcinogenesis triggered by heme iron from red meat
Nina Seiwert et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2020)
Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis-A Novel Form of Non-Apoptotic Cell Death?
Ricardo U. Macias-Rodriguez et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
The microbiome and inflammatory bowel disease
Kerri L. Glassner et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)
Floridoside Exhibits Antioxidant Properties by Activating HO-1 Expression via p38/ERK MAPK Pathway
Tingting Niu et al.
MARINE DRUGS (2020)
Endothelin-converting enzyme-1c promotes stem cell traits and aggressiveness in colorectal cancer cells
Pablo Perez-Moreno et al.
MOLECULAR ONCOLOGY (2020)
Mevastatin-Induced AP-1-Dependent HO-1 Expression Suppresses Vascular Cell Adhesion Molecule-1 Expression and Monocyte Adhesion on Human Pulmonary Alveolar Epithelial Cells Challenged with TNF-α
Chuen-Mao Yang et al.
BIOMOLECULES (2020)
The heme-regulatory motifs of heme oxygenase-2 contribute to the transfer of heme to the catalytic site for degradation
Angela S. Fleischhacker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Insight into the mechanism of ferroptosis inhibition by ferrostatin-1
Giovanni Miotto et al.
REDOX BIOLOGY (2020)
Synthesis and in vitro characterization of the genotoxic, mutagenic and cell-transforming potential of nitrosylated heme
Tina Kostka et al.
ARCHIVES OF TOXICOLOGY (2020)
Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats (vol 19, 15, 2020)
Wei Hou et al.
BIOMEDICAL ENGINEERING ONLINE (2020)
Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities
Carina Neitzel et al.
CANCERS (2020)
Heme oxygenase-2 is post-translationally regulated by heme occupancy in the catalytic site
Liu Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron
Nina Seiwert et al.
CELL DEATH & DISEASE (2020)
The Keap1/Nrf2 Signaling Pathway in the Thyroid-2020 Update
Christina Thanas et al.
ANTIOXIDANTS (2020)
Optimization of fecal sample processing for microbiome study - The journey from bathroom to bench
Wei-Kai Wu et al.
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION (2019)
Heme detoxification by heme oxygenase-1 reinstates proliferative and immune balances upon genotoxic tissue injury
Andreas Hedblom et al.
CELL DEATH & DISEASE (2019)
BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
Clotilde Wiel et al.
CELL (2019)
Betula etnensis Raf. (Betulaceae) Extract Induced HO-1 Expression and Ferroptosis Cell Death in Human Colon Cancer Cells
Giuseppe Antonio Malfa et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Pro-apoptotic effect of haem oxygenase-1 in human colorectal carcinoma cells via endoplasmic reticular stress
Ming-Shun Wu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
Lifestyle and dietary environmental factors in colorectal cancer susceptibility
Neil Murphy et al.
MOLECULAR ASPECTS OF MEDICINE (2019)
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies
NaNa Keum et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)
Oxygenated Polycyclic aromatic hydrocarbons (Oxy-PAHs) facilitate lung cancer metastasis by epigenetically regulating the epithelial-to-mesenchymal transition (EMT)
Dan Li et al.
ENVIRONMENTAL POLLUTION (2019)
Pharmacological versus genetic inhibition of heme oxygenase-1-the comparison of metalloporphyrins, shRNA and CRISPR/Cas9 system
Olga Mucha et al.
ACTA BIOCHIMICA POLONICA (2018)
Heme oxygenase-1 prevents murine intestinal inflammation
Tomohisa Takagi et al.
JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2018)
Relationship between serum bilirubin levels and cardiovascular disease
Sunghwan Suh et al.
PLOS ONE (2018)
microRNA-494 Favors HO-1 Expression in Neuroblastoma Cells Exposed to Oxidative Stress in a Bach1-Independent Way
Sabrina Piras et al.
FRONTIERS IN ONCOLOGY (2018)
Heme oxygenase-2 suppresses acute inflammation and improves the survival of skin allografts
Renjin Chen et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2-/- mice
Roja Barikbin et al.
SCIENTIFIC REPORTS (2018)
HMOX-1 inhibits TGF-β-induced epithelial-mesenchymal transition in the MCF-7 breast cancer cell line
Xiaofeng Zhu et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017)
The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-jB Inhibition
Lijing Zhang et al.
MOLECULAR MEDICINE (2017)
Bilirubin Prevents Atherosclerotic Lesion Formation in Low-Density Lipoprotein Receptor-Deficient Mice by Inhibiting Endothelial VCAM-1 and ICAM-1 Signaling
Megan E. Vogel et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2017)
Lipid peroxidation in cell death
Michael M. Gaschler et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
Xiaofang Sun et al.
HEPATOLOGY (2016)
Enhancement of DEN-induced liver tumorigenesis in heme oxygenase-1 G143H mutant transgenic mice
Jianfeng Jin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Prevention of Barrier Disruption by Heme Oxygenase-1 in Intestinal Bleeding Model
Reiko Akagi et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2016)
Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation
Johann Greil et al.
HAEMATOLOGICA (2016)
Simple rules for passive diffusion through the nuclear pore complex
Benjamin L. Timney et al.
JOURNAL OF CELL BIOLOGY (2016)
Relationship Between the Serum Total Bilirubin and Inflammation in Patients With Psoriasis Vulgaris
Zhen-Xing Zhou et al.
JOURNAL OF CLINICAL LABORATORY ANALYSIS (2016)
DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP
Maximilian Mimmler et al.
NUCLEIC ACIDS RESEARCH (2016)
The non-canonical functions of the heme oxygenases
Luca Vanella et al.
ONCOTARGET (2016)
Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation
Johann Greil et al.
HAEMATOLOGICA (2016)
Bilirubin is an Endogenous Antioxidant in Human Vascular Endothelial Cells
Lovro Ziberna et al.
SCIENTIFIC REPORTS (2016)
Blocking heme oxygenase-1 by zinc protoporphyrin reduces tumor hypoxia-mediated VEGF release and inhibits tumor angiogenesis as a potential therapeutic agent against colorectal cancer
Chun-Chia Cheng et al.
JOURNAL OF BIOMEDICAL SCIENCE (2016)
DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis
Joerg Fahrer et al.
CARCINOGENESIS (2015)
High Glucose Promotes Tumor Invasion and Increases Metastasis-Associated Protein Expression in Human Lung Epithelial Cells by Upregulating Heme Oxygenase-1 via Reactive Oxygen Species or the TGF-beta(1)/PI3K/Akt Signaling Pathway
Xiaowen Kang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
Identification of heme oxygenase-1 stimulators by a convenient ELISA-based bilirubin quantification assay
Hannelore Ruecker et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Nrf2-heme oxygenase-1 axis in mucoepidermoid carcinoma of the lung: Antitumoral effects associated with down-regulation of matrix metalloproteinases
Magdalena Tertil et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice
R. Tolba et al.
LABORATORY ANIMALS (2015)
Theoretical considerations for thresholds in chemical carcinogenesis
Adam D. Thomas et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2015)
The global burden of IBD: from 2015 to 2025
Gilaad G. Kaplan
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2015)
Heme oxygenase-1 promotes tumor progression and metastasis of colorectal carcinoma cells by inhibiting antitumor immunity
Geom Seog Seo et al.
ONCOTARGET (2015)
Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
Min-Young Kwon et al.
ONCOTARGET (2015)
Only three driver gene mutations are required for the development of lung and colorectal cancers
Cristian Tomasetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathway
Yu-Jia Chang et al.
TUMOR BIOLOGY (2015)
The regulation of MMP targeting to invadopodia during cancer metastasis
Abitha Jacob et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2015)
Functional MicroRNA Library Screening Identifies the HypoxaMiR MiR-24 as a Potent Regulator of Smooth Muscle Cell Proliferation and Vascularization
Jan Fiedler et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
The Crosstalk Between Nrf2 and AMPK Signal Pathways Is Important for the Anti-Inflammatory Effect of Berberine in LPS-Stimulated Macrophages and Endotoxin-Shocked Mice
Chunfen Mo et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Andrographolide inhibits TNFot-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells
Chia-Yang Lu et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice
Gennadiy Kovtunovych et al.
BLOOD (2014)
Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity
Hongzhuan Yin et al.
BMC CANCER (2014)
CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis
Matilde Todaro et al.
CELL STEM CELL (2014)
Pharmacological application of carbon monoxide ameliorates islet-directed autoimmunity in mice via anti-inflammatory and anti-apoptotic effects
Ivana Nikolic et al.
DIABETOLOGIA (2014)
Heme oxygenase-1 has antitumoral effects in colorectal cancer: Involvement of p53
Nancy Carolina Andres et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2014)
15-Deoxy-Δ12,14-prostaglandin J2 induces p53 expression through Nrf2-mediated upregulation of heme oxygenase-1 in human breast cancer cells
D. H. Kim et al.
FREE RADICAL RESEARCH (2014)
Nuclear Heme Oxygenase-1 (HO-1) Modulates Subcellular Distribution and Activation of Nrf2, Impacting Metabolic and Anti-oxidant Defenses
Chhanda Biswas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation
Barbara Wegiel et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Early induction of oxidative stress in a mouse model of Alzheimer's disease with heme oxygenase activity
Sanli Xing et al.
MOLECULAR MEDICINE REPORTS (2014)
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Jose Pedro Friedmann Angeli et al.
NATURE CELL BIOLOGY (2014)
Sanguinarine inhibits invasiveness and the MMP-9 and COX-2 expression in TPA-induced breast cancer cells by inducing HO-1 expression
Sun Young Park et al.
ONCOLOGY REPORTS (2014)
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
Antonio Ayala et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
Regulation and Novel Action of Thymidine Phosphorylase in Non-Small Cell Lung Cancer: Crosstalk with Nrf2 and HO-1
Magdalena Tertil et al.
PLOS ONE (2014)
Epidermal Growth Factor Stimulates Nuclear Factor-κB Activation and Heme Oxygenase-1 Expression via c-Src, NADPH Oxidase, PI3K, and Akt in Human Colon Cancer Cells
Gi-Shih Lien et al.
PLOS ONE (2014)
The γH2AX Assay for Genotoxic and Nongenotoxic Agents: Comparison of H2AX Phosphorylation with Cell Death Response
Teodora Nikolova et al.
TOXICOLOGICAL SCIENCES (2014)
The balance between cell cycle arrest and cell proliferation: control by the extracellular matrix and by contact inhibition
Claude Gerard et al.
INTERFACE FOCUS (2014)
Heme-oxygenase-1 implications in cell morphology and the adhesive behavior of prostate cancer cells
Geraldine Gueron et al.
ONCOTARGET (2014)
Like iron in the blood of the people: the requirement for heme trafficking in iron metabolism
Tamara Korolnek et al.
FRONTIERS IN PHARMACOLOGY (2014)
Glutathione peroxidases
Regina Brigelius-Flohe et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
Dietary heme induces acute oxidative stress, but delayed cytotoxicity and compensatory hyperproliferation in mouse colon
Noortje Ijssennagger et al.
CARCINOGENESIS (2013)
O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer
Joerg Fahrer et al.
CARCINOGENESIS (2013)
Immuno-spin trapping of heme-induced protein radicals: Implications for heme oxygenase-1 induction and heme degradation
Ashutosh Kumar et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Carbon Monoxide and Heme Oxygenase-1 Prevent Intestinal Inflammation in Mice by Promoting Bacterial Clearance
Joseph C. Onyiah et al.
GASTROENTEROLOGY (2013)
Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury
Abolfazl Zarjou et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
Yoshinobu Ichimura et al.
MOLECULAR CELL (2013)
Cross-talk between microRNAs, nuclear factor E2-related factor 2, and heme oxygenase-1 in ochratoxin A-induced toxic effects in renal proximal tubular epithelial cells
Anna Stachurska et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2013)
TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation
P-H Lin et al.
ONCOGENE (2013)
Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: Role of beta-catenin/hnRNPK signaling
Guang Yang et al.
REDOX BIOLOGY (2013)
MiR-135a promotes growth and invasion of colorectal cancer via metastasis suppressor 1 in vitro
Weiwei Zhou et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Flavonoids Protect Cerebrovascular Endothelial Cells through Nrf2 and PI3K from β-Amyloid Peptide-Induced Oxidative Damage
Yuan-Di Xi et al.
CURRENT NEUROVASCULAR RESEARCH (2012)
Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol
Yehonatan Gottlieb et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2012)
Diet and Nutrient Factors in Colorectal Cancer Risk
Ashley J. Vargas et al.
NUTRITION IN CLINICAL PRACTICE (2012)
Self-regulated viscous channel in the nuclear pore complex
Jiong Ma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Involvement of heme oxygenase-1 in Korean colon cancer
Kyoung Ah Kang et al.
TUMOR BIOLOGY (2012)
Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival
Xiao-ming Liu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
Heme oxygenase 1 is induced by miR-155 via reduced BACH1 translation in endothelial cells
Kati H. Pulkkinen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
miR-200a Regulates Nrf2 Activation by Targeting Keap1 mRNA in Breast Cancer Cells
Gabriel Eades et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
An Anti-Inflammatory Role for Carbon Monoxide and Heme Oxygenase-1 in Chronic Th2-Mediated Murine Colitis
Shehzad Z. Sheikh et al.
JOURNAL OF IMMUNOLOGY (2011)
A polymorphism located at an ATG transcription start site of the heme oxygenase-2 gene is associated with classical Parkinson's disease
Pedro Ayuso et al.
PHARMACOGENETICS AND GENOMICS (2011)
Heme oxygenase-1 and carbon monoxide modulate DNA repair through ataxia-telangiectasia mutated (ATM) protein
Leo E. Otterbein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
Robert D. Schreiber et al.
SCIENCE (2011)
HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage
Luca Vanella et al.
BONE (2010)
Intestinal Ferritin H Is Required for an Accurate Control of Iron Absorption
Liviu Vanoaica et al.
CELL METABOLISM (2010)
Inhalation of Carbon Monoxide Ameliorates TNBS-Induced Colitis in Mice Through the Inhibition of TNF-α Expression
Tomohisa Takagi et al.
DIGESTIVE DISEASES AND SCIENCES (2010)
Chemistry and biochemistry of lipid peroxidation products
F. Gueraud et al.
FREE RADICAL RESEARCH (2010)
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
Masaaki Komatsu et al.
NATURE CELL BIOLOGY (2010)
Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions
Marcienne M. Wright et al.
BIOCHEMICAL JOURNAL (2009)
Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis
Emina H. Huang et al.
CANCER RESEARCH (2009)
Gene Transfer of Inducible Nitric Oxide Synthase Affords Cardioprotection by Upregulating Heme Oxygenase-1 Via a Nuclear Factor-κB-Dependent Pathway
Qianhong Li et al.
CIRCULATION (2009)
HO-1-mediated macroautophagy: a mechanism for unregulated iron deposition in aging and degenerating neural tissues
Hillel Zukor et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Critical Role of Endogenous Heme Oxygenase 1 as a Tuner of the Invasive Potential of Prostate Cancer Cells
Geraldine Gueron et al.
MOLECULAR CANCER RESEARCH (2009)
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Molecular Origins of Cancer: Molecular Basis of Colorectal Cancer.
Sanford D. Markowitz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Bilirubin and glutathione have complementary antioxidant and cytoprotective roles
Thomas W. Sedlak et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Carbon monoxide activates NF-κB via ROS generation and Akt pathways to protect against cell death of hepatocytes
Hoe Suk Kim et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
Revisiting heme mechanisms. a perspective on the mechanisms of nitric oxide synthase (NOS), heme oxygenase (HO), and cytochrome p450s (CYP450s)
Yaoqiu Zhu et al.
BIOCHEMISTRY (2008)
Zinc protoporphyrin IX, a heme oxygenase-I inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice
Dominika Nowis et al.
BMC CANCER (2008)
CD44 is of Functional Importance for Colorectal Cancer Stem Cells
Lei Du et al.
CLINICAL CANCER RESEARCH (2008)
Inducers of heme oxygenase-1
M. L. Ferrandiz et al.
CURRENT PHARMACEUTICAL DESIGN (2008)
Inhibition of heme oxygenase 1 expression by small interfering RNA decreases orthotopic tumor growth in livers of mice
Gabriele Sass et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Two-dimensional differential gel electrophoresis/analysis of diethylnitrosamine induced rat hepatocellular carcinoma
Yanting Qi et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Increased intestinal expression of heme oxygenase-1 and its localization in patients with ulcerative colitis
Tomohisa Takagi et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2008)
Hereditary colorectal cancer syndromes: molecular genetics, genetic counseling, diagnosis and management
Henry T. Lynch et al.
FAMILIAL CANCER (2008)
Expression and characterization of full-length human heme oxygenase-1: The presence of intact membrane-binding region leads to increased binding affinity for NADPH cytochrome P450 reductase
Warren J. Huber et al.
BIOCHEMISTRY (2007)
Heme induces ubiquitination and degradation of the transcription factor bach1
Yukari Zenke-Kawasaki et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress
Qing Lin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Non-heme induction of heme oxygenase-1 does not alter cellular iron metabolism
Alex D. Sheftel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species
Brian S. Zuckerbraun et al.
FASEB JOURNAL (2007)
Hypoxia-inducible factor 1α stabilization by carbon monoxide results in cytoprotective preconditioning
Beek Y. Chin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Attenuation of oxidative injury after induction of experimental intracerebral hemorrhage in heme oxygenase-2 knockout mice
Yan Qu et al.
JOURNAL OF NEUROSURGERY (2007)
Adaptation of energy metabolism in breast cancer brain metastases
Emily I. Chen et al.
CANCER RESEARCH (2007)
How many transcription factors does it take to turn on the heme oxygenase-1 gene?
Jawed Alam et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2007)
Colonic expression of heme oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer
Jan C. Becker et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2007)
What is responsible for the initiating chemistry of iron-mediated lipid peroxidation: An update
Zhiyong Cheng et al.
CHEMICAL REVIEWS (2007)
Overexpression of heme oxygenase-1 in murine melanoma - Increased proliferation and viability of tumor cells, decreased survival of mice
Halina Was et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
New marker of colon cancer risk associated with heme intake:: 1,4-dihydroxynonane mercapturic acid
Fabrice Pierre et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2006)
Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts
Kiichi Nakahira et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity
D. Nowis et al.
ONCOGENE (2006)
Heme oxygenase 2 is neuroprotective against intracerebral hemorrhage
Jian Wang et al.
NEUROBIOLOGY OF DISEASE (2006)
Carbon monoxide orchestrates a protective response through PPARγ
Martin Bilban et al.
IMMUNITY (2006)
Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction
Alvin I. Goodman et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Heme oxygenase-1 inhibits apoptosis in Caco-2 cells via activation of Akt pathway
Jerome Busserolles et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2006)
Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway
RAF Hegazi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Carbon monoxide: Endogenous production, physiological functions, and pharmacological applications
LY Wu et al.
PHARMACOLOGICAL REVIEWS (2005)
Molecular basis of heme oxygenase-1 induction: Implications for chemoprevention and chemoprotection
A Prawan et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Heme oxygenase 1 (HO-1) regulates osteoclastogenesis and bone resorption
J Zwerina et al.
FASEB JOURNAL (2005)
Genetic evidence that small Maf proteins are essential for the activation of antioxidant response element-dependent genes
F Katsuoka et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation
R Ockaili et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle
C Taillé et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Analysis of intestinal haem-oxygenase-1 (HO-1) in clinical and experimental colitis
G Paul et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2005)
Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury
XC Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Heme-induced heme oxygenase-1 (HO-1) in human monocytes inhibits apoptosis despite caspase-3 up-regulation
D Lang et al.
INTERNATIONAL IMMUNOLOGY (2005)
Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network
JY Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Heme oxygenase-1-derived carbon monoxide protects hearts from transplant-associated ischemia reperfusion injury
Y Akamatsu et al.
FASEB JOURNAL (2004)
Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells
ZM Liu et al.
ONCOGENE (2004)
Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide
GA Ricchetti et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Heme oxygenase-1 modulates early inflammatory responses - Evidence from the heme oxygenase-1-deficient mouse
MH Kapturczak et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Heme oxygenase-1 protects against apoptosis induced by tumor necrosis factor-α and cycloheximide in papillary thyroid carcinoma cells
GG Chen et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
Diallyl sulfide induces heme oxygenase-1 through MAPK pathway
PF Gong et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Characterization of rat heme oxygenase-3 gene. Implication of processed pseudogenes derived from heme oxygenase-2 gene
S Hayashi et al.
GENE (2004)
Phosphorylation and hypoxia-induced heme oxygenase-1 gene expression in cardiomyocytes
G Wu et al.
JOURNAL OF CARDIAC FAILURE (2004)
Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1
H Suzuki et al.
EMBO JOURNAL (2004)
Caveolae compartmentalization of heme oxygenase-1 in endothelial cells
HP Kim et al.
FASEB JOURNAL (2004)
Ferritin heavy chain upregulation by NF-κB inhibits TNFα-induced apoptosis by suppressing reactive oxygen species
CG Pham et al.
CELL (2004)
Cooperative effect of biliverdin and carbon monoxide on survival of mice in immune-mediated liver injury
G Sass et al.
HEPATOLOGY (2004)
Carbon monoxide neurotransmission activated by CK2 phosphorylation of heme oxygenase-2
D Boehning et al.
NEURON (2003)
Stereo selectivity of each of the three steps of the heme oxygenase reaction:: Hemin to meso-hydroxyhemin, meso-hydroxyhemin to verdoheme, and verdoheme to biliverdin
XH Zhang et al.
BIOCHEMISTRY (2003)
Carbon monoxide modulates Fas/Fas ligand, caspases, and Bcl-2 family proteins via the p38α mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury
XC Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat Hepatocytes
T Kietzmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Does heme oxygenase-1 have a role in Caco-2 cell cycle progression?
A Uc et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2003)
Prophylaxis of pouchitis onset with probiotic therapy: A double-blind, placebo-controlled trial
P Gionchetti et al.
GASTROENTEROLOGY (2003)
Protective role of heme oxygenase-1 in the intestinal tissue injury in an experimental model of sepsis
H Fujii et al.
CRITICAL CARE MEDICINE (2003)
Biliverdin reductase:: A major physiologic cytoprotectant
DE Barañano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
HC Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C→T:A mutations
S Jones et al.
HUMAN MOLECULAR GENETICS (2002)
Pro-oxidant and cytotoxic effects of circulating heme
V Jeney et al.
BLOOD (2002)
Role of heme oxygenase-1 in hypoxia-reoxygenation: requirement of substrate heme to promote cardioprotection
R Foresti et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1
K Ogawa et al.
EMBO JOURNAL (2001)
Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis
S Brouard et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
LE Otterbein et al.
NATURE MEDICINE (2000)
Share Paper
