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Moonlighting Proteins: Diverse Functions Found in Fungi

Journal

JOURNAL OF FUNGI
Volume 9, Issue 11, Pages -

Publisher

MDPI
DOI: 10.3390/jof9111107

Keywords

moonlighting protein; multifunctional; RNA binding proteins; multiprotein complex; enzymes; transcription factor

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This mini-review discusses examples of moonlighting proteins in fungi, revealing their roles in transcription and DNA metabolism, translation and RNA metabolism, protein folding, regulation of protein function, and their interaction with other cell types and host proteins.
Moonlighting proteins combine multiple functions in one polypeptide chain. An increasing number of moonlighting proteins are being found in diverse fungal taxa that vary in morphology, life cycle, and ecological niche. In this mini-review we discuss examples of moonlighting proteins in fungi that illustrate their roles in transcription and DNA metabolism, translation and RNA metabolism, protein folding, and regulation of protein function, and their interaction with other cell types and host proteins.

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