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Label-free cell separation and sorting in microfluidic systems
Daniel R. Gossett et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2010)
A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor Specimens
Jing Sun et al.
CANCER RESEARCH (2010)
Miniaturization and Parallelization of Biological and Chemical Assays in Microfluidic Devices
Saurabh Vyawahare et al.
CHEMISTRY & BIOLOGY (2010)
3D microchannel co-culture: method and biological validation
Maret Bauer et al.
INTEGRATIVE BIOLOGY (2010)
A novel pre-clinical in vivo mouse model for malignant brain tumor growth and invasion
Laura M. Shelton et al.
JOURNAL OF NEURO-ONCOLOGY (2010)
Adhesion based detection, sorting and enrichment of cells in microfluidic Lab-on-Chip devices
Tohid Fatanat Didar et al.
LAB ON A CHIP (2010)
Genetic instability and diminished differentiation capacity in long-term cultured mouse neurosphere cells
Vladimir Vukicevic et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2010)
Microfluidic Culture Models of Tumor Angiogenesis
Abraham D. Stroock et al.
TISSUE ENGINEERING PART A (2010)
The expanding universe of transposon technologies for gene and cell engineering
Zoltan Ivics et al.
MOBILE DNA (2010)
Mesenchymal Migration as a Therapeutic Target in Glioblastoma
Jessie Zhong et al.
JOURNAL OF ONCOLOGY (2010)
The pig model in brain imaging and neurosurgery
P. Sauleau et al.
ANIMAL (2009)
Isolation and characterization of cancer stem like cells in human glioblastoma cell lines
Lei Qiang et al.
CANCER LETTERS (2009)
De novo Induction of Genetically Engineered Brain Tumors in Mice Using Plasmid DNA
Stephen M. Wiesner et al.
CANCER RESEARCH (2009)
Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens
Steven M. Pollard et al.
CELL STEM CELL (2009)
Spontaneous migration of cancer cells under conditions of mechanical confinement
Daniel Irimia et al.
INTEGRATIVE BIOLOGY (2009)
From the cellular perspective: exploring differences in the cellular baseline in macroscale and microfluidic cultures
Amy L. Paguirigan et al.
INTEGRATIVE BIOLOGY (2009)
Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas
Rolf F. Barth et al.
JOURNAL OF NEURO-ONCOLOGY (2009)
A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics
Colin L. Walsh et al.
LAB ON A CHIP (2009)
Biological implications of polydimethylsiloxane-based microfluidic cell culture
Keil J. Regehr et al.
LAB ON A CHIP (2009)
Development of a novel mouse glioma model using lentiviral vectors
Tomotoshi Marumoto et al.
NATURE MEDICINE (2009)
Spheroid-based drug screen: considerations and practical approach
Juergen Friedrich et al.
NATURE PROTOCOLS (2009)
IDH1 and IDH2 Mutations in Gliomas
Hai Yan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture
Olivier Preynat-Seauve et al.
STEM CELLS (2009)
Modeling Adult Gliomas Using RCAS/t-va Technology
Dolores Hambardzumyan et al.
TRANSLATIONAL ONCOLOGY (2009)
Metastasis: from dissemination to organ-specific colonization
Don X. Nguyen et al.
NATURE REVIEWS CANCER (2009)
Phenotypic and genotypic characterization of orthotopic human glioma models and its relevance for the study of anti-glioma therapy
An Claes et al.
BRAIN PATHOLOGY (2008)
Different effects of KCa and KATP agonists on brain tumor permeability between syngeneic and allogeneic rat models
Keith L. Black et al.
BRAIN RESEARCH (2008)
Tissue-type plasminogen activator has antiangiogenic properties without effect on tumor growth in a rat C6 glioma model
F. Solly et al.
CANCER GENE THERAPY (2008)
Molecular targeting and treatment of composite EGFR and EGFRvIII-positive gliomas using boronated monoclonal antibodies
Weilian Yang et al.
CLINICAL CANCER RESEARCH (2008)
Akt-Dependent Proapoptotic Effects of Dietary Restriction on Late-Stage Management of a Phosphatase and Tensin Homologue/Tuberous Sclerosis Complex 2-Deficient Mouse Astrocytoma
Jeremy Marsh et al.
CLINICAL CANCER RESEARCH (2008)
Biodisposition and metabolism of [18F]fluorocholine in 9L glioma cells and 9L glioma-bearing fisher rats
Aditya Bansal et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2008)
Phenyl-tert-butylnitrone induces tumor regression and decreases angiogenesis in a C6 rat glioma model
Sabrina Doblas et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Intratumoral vs systemic administration of meta-tetrahydroxyphenylchlorin for photodynamic therapy of malignant gliomas: Assessment of uptake and spatial distribution in C6 rat glioma model
S. Mannino et al.
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY (2008)
Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme
Drazen Zagorac et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2008)
Intravenous administration of arsenic trioxide encapsulated in liposomes inhibits the growth of C6 gliomas in rat brains
Shiguang Zhao et al.
JOURNAL OF CHEMOTHERAPY (2008)
Efficacy of suicide gene therapy in hypoxic rat 9L glioma cells
S. Kumar et al.
JOURNAL OF NEURO-ONCOLOGY (2008)
Use of trans sodium crocetinate for sensitizing glioblastoma multiforme to radiation
Jason Sheeran et al.
JOURNAL OF NEUROSURGERY (2008)
Metabolic gene regulation in a dynamically changing environment
Matthew R. Bennett et al.
NATURE (2008)
The effects of systemic and intratumoral interleukin-12 treatment in C6 rat glioma model
Necmettin Tanriover et al.
NEUROLOGICAL RESEARCH (2008)
Assessment of blood volume, vessel size, and the expression of angiogenic factors in two rat glioma models: a longitudinal in vivo and ex vivo study
Samuel Valable et al.
NMR IN BIOMEDICINE (2008)
Dibromoacetonitrile-induced protein oxidation and inhibition of proteasomal activity in rat glioma cells
E. Ahmed Ahmed et al.
TOXICOLOGY LETTERS (2008)
New dimensions in tumor immunology: what does 3D culture reveal?
Chantal Feder-Mengus et al.
TRENDS IN MOLECULAR MEDICINE (2008)
Molecular and cellular response of the most extensively used rodent glioma models to radiation and/or cisplatin
Zuzana Bencokova et al.
JOURNAL OF NEURO-ONCOLOGY (2008)
Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy
Kazuhiko Kurozumi et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Serum GFAP is a diagnostic marker for glioblastoma multiforme
C. S. Jung et al.
BRAIN (2007)
Versatile, fully automated, microfluidic cell culture system
Rafael Gomez-Sjoeberg et al.
ANALYTICAL CHEMISTRY (2007)
Unique patterns of diffusion directionality in rat brain tumors revealed by high-resolution diffusion tensor MRI
Jiangyang Zhang et al.
MAGNETIC RESONANCE IN MEDICINE (2007)
Using behavioral measurement to assess tumor progression and functional outcome after antiangiogenic treatment in mouse glioma models
Hongyan Yang et al.
BEHAVIOURAL BRAIN RESEARCH (2007)
The selective poly(ADP-ribose) polymerase-1(2) inhibitor, CEP-8983, increases the sensitivity of chemoresistant tumor cells to temozolomide and irinotecan but does not potentiate myelotoxicity
Sheila Miknyoczki et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Standardization and detailed characterization of the syngeneic Fischer/F98 glioma model
David Mathieu et al.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES (2007)
Validation of dynamic contrast-enhanced magnetic resonance imaging-derived vascular permeability measurements using quantitative autoradiography in the RG2 rat brain tumor model
Moira C. Ferrier et al.
NEOPLASIA (2007)
Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors
Damien Faury et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Multi-step microfluidic device for studying cancer metastasis
K. C. Chaw et al.
LAB ON A CHIP (2007)
The use of pigs in neuroscience: Modeling brain disorders
Nanna Marie Lind et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2007)
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
PDMS absorption of small molecules and consequences in microfluidic applications
Michael W. Toepke et al.
LAB ON A CHIP (2006)
Proton and sodium MRI assessment of emerging tumor chemotherapeutic resistance
Victor D. Schepkin et al.
NMR IN BIOMEDICINE (2006)
High-grade glioma formation results from postnatal Pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model
Qingxia Wei et al.
CANCER RESEARCH (2006)
Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy
Tunde Szatmari et al.
CANCER SCIENCE (2006)
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
Jeongwu Lee et al.
CANCER CELL (2006)
MR-pathological comparison in F98-Fischer glioma model using a human gantry
J Blanchard et al.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES (2006)
Prolonged survival of Fischer rats bearing F98 glioma after iodine-enhanced synchrotron stereotactic radiotherapy
JF Adam et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2006)
Barriers to carrier mediated drug and gene delivery to brain tumors
GH Huynh et al.
JOURNAL OF CONTROLLED RELEASE (2006)
'Pseudopalisading' necrosis in glioblastoma: A familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis
Yuan Rong et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
The natural history of EGFR and EGFRvIII in glioblastoma patients
AB Heimberger et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2005)
Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature
MV Backer et al.
MOLECULAR CANCER THERAPEUTICS (2005)
EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion
M Nakada et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Flexible versus rigid catheters for chronic administration of exogenous agents into central nervous system tissues
M Guarnieri et al.
JOURNAL OF NEUROSCIENCE METHODS (2005)
Influence of in vivo growth on human glioma cell line gene expression:: Convergent profiles under orthotopic conditions
K Camphausen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Recombinant Sendai virus vector induces complete remission of established brain tumors through efficient Interleukin-2 gene transfer in vaccinated rats
Y Iwadate et al.
CLINICAL CANCER RESEARCH (2005)
The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo
NM Tsai et al.
CLINICAL CANCER RESEARCH (2005)
Heat shock protein 72 expression allows permissive replication of oncolytic adenovirus dl1520 (ONYX-015) in rat glioblastoma cells
Jonathan Madara et al.
MOLECULAR CANCER (2005)
High interstitial fluid pressure -: An obstacle in cancer therapy
CH Heldin et al.
NATURE REVIEWS CANCER (2004)
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
R Galli et al.
CANCER RESEARCH (2004)
Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: Racine and nonhuman primates
WQ Yang et al.
CLINICAL CANCER RESEARCH (2004)
Effects of dose, intervention time, and radionuclide on sodium iodide symporter (NIS)-targeted radionuclide therapy
DHY Shen et al.
GENE THERAPY (2004)
Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma
Patrizia Tunici et al.
MOLECULAR CANCER (2004)
Molecular mechanisms of glioma invasiveness: The role of proteases
JS Rao
NATURE REVIEWS CANCER (2003)
Local tumour irradiation enhances the anti-tumour effect of a double-suicide gene therapy system in a murine glioma model
S Desaknai et al.
JOURNAL OF GENE MEDICINE (2003)
Platelet-derived growth factor-b enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment
P Guo et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Microfluidic devices fabricated in poly(dimethylsiloxane) for biological studies
SK Sia et al.
ELECTROPHORESIS (2003)
Induction of glioblastoma multiforme in nonhuman primates after therapeutic doses of fractionated whole-brain radiation therapy
RR Lonser et al.
JOURNAL OF NEUROSURGERY (2002)
NOD/SCID/γcnull mouse:: an excellent recipient mouse model for engraftment of human cells
M Ito et al.
BLOOD (2002)
In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas
JY Cho et al.
GENE THERAPY (2002)
Increased endothelial vesicular transport correlates with increased blood-tumor barrier permeability induced by bradykinin and leukotriene C4
K Hashizume et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)
Regulation of blood-brain tumor barrier permeability by calcium-activated potassium channels
NS Ningaraj et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
The development of necrosis and apoptosis in glioma: experimental findings using spheroid culture systems
HS Bell et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2001)
Modified immunoregulation associated with interferon-γ treatment of rat glioma
S Oshiro et al.
NEUROLOGICAL RESEARCH (2001)
Limitations of the C6/Wistar rat intracerebral glioma model: Implications for evaluating immunotherapy
AT Parsa et al.
NEUROSURGERY (2000)
Vascular apoptosis and involution in gliomas precede neovascularization: A novel concept for glioma growth and angiogenesis
D Zagzag et al.
LABORATORY INVESTIGATION (2000)
IFN-β gene therapy induces systemic antitumor immunity against malignant glioma
A Natsume et al.
JOURNAL OF NEURO-ONCOLOGY (2000)
Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems
DT Chiu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)