Related references
Note: Only part of the references are listed.The NuRD complex cooperates with SALL4 to orchestrate reprogramming
Bo Wang et al.
NATURE COMMUNICATIONS (2023)
Improved Long-Term Survival of Patients with Recurrent Medulloblastoma Treated with a MEMMAT-like Metronomic Antiangiogenic Approach
Irene Slavc et al.
CANCERS (2022)
SALL4 controls cell fate in response to DNA base composition
Raphael Pantier et al.
MOLECULAR CELL (2021)
Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression
Nikki R. Kong et al.
CELL REPORTS (2021)
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma
Paola Infante et al.
CANCER LETTERS (2021)
Up-Regulation of SALL4 Is Associated With Survival and Progression via Putative WNT Pathway in Gastric Cancer
Yang Yang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
SALL Proteins; Common and Antagonistic Roles in Cancer
Claudia Alvarez et al.
CANCERS (2021)
Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4
Johanna Diener et al.
NATURE COMMUNICATIONS (2021)
Medulloblastoma: Molecular understanding, treatment evolution, and new developments
Xiaohua Liu et al.
PHARMACOLOGY & THERAPEUTICS (2020)
Crystal structure of the SALL4-pomalidomide-cereblon-DDB1 complex
Mary E. Matyskiela et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)
DUBs Activating the Hedgehog Signaling Pathway: A Promising Therapeutic Target in Cancer
Francesca Bufalieri et al.
CANCERS (2020)
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma
Ludovica Lospinoso Severini et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2020)
SALL4 promotes tumor progression in breast cancer by targeting EMT
Teng Chen et al.
MOLECULAR CARCINOGENESIS (2020)
Medulloblastomics revisited: biological and clinical insights from thousands of patients
Volker Hovestadt et al.
NATURE REVIEWS CANCER (2020)
SALL4 promotes the tumorigenicity of cervical cancer cells through activation of the Wnt/β-catenin pathway via CTNNB1
Mei Chen et al.
CANCER SCIENCE (2019)
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
Francesca Bufalieri et al.
NATURE COMMUNICATIONS (2019)
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2
Eleonora Spiombi et al.
ONCOGENESIS (2019)
A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth
Ludovica Lospinoso Severini et al.
CANCERS (2019)
On-Column Dimethylation with Capillary Liquid Chromatography Tandem Mass Spectrometry for Online Determination of Neuropeptides in Rat Brain Microdialysate
Rachael E. Wilson et al.
ANALYTICAL CHEMISTRY (2018)
NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma
Alexandra Garancher et al.
CANCER CELL (2018)
Itch/beta-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
Paola Infante et al.
NATURE COMMUNICATIONS (2018)
Medulloblastoma: From Molecular Subgroups to Molecular Targeted Therapies
Jun Wang et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 41 (2018)
Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome
Katherine A. Donovan et al.
ELIFE (2018)
Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN
Quinlan L. Sievers et al.
SCIENCE (2018)
NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus
Shafi Kuchay et al.
CELL REPORTS (2018)
Coexpression of SALL4 with HDAC1 and/or HDAC2 is associated with underexpression of PTEN and poor prognosis in patients with hepatocellular carcinoma
Huanlin Wang et al.
HUMAN PATHOLOGY (2017)
SALL4 suppresses PTEN expression to promote glioma cell proliferation via PI3K/AKT signaling pathway
Chuanjin Liu et al.
JOURNAL OF NEURO-ONCOLOGY (2017)
Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
Sonia Coni et al.
SCIENTIFIC REPORTS (2017)
ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas
Katie B. Grausam et al.
CANCER RESEARCH (2017)
Intertumoral Heterogeneity within Medulloblastoma Subgroups
Florence M. G. Cavalli et al.
CANCER CELL (2017)
HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma
Yanxin Pei et al.
CANCER CELL (2016)
SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development
Madalina Raducu et al.
EMBO JOURNAL (2016)
Cooperative Action between SALL4A and TET Proteins in Stepwise Oxidation of 5-Methylcytosine
Jun Xiong et al.
MOLECULAR CELL (2016)
Leukemic survival factor SALL4 contributes to defective DNA damage repair
F. Wang et al.
ONCOGENE (2016)
The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint
Laura Di Magno et al.
Oncotarget (2016)
RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors
Xuesong Zhao et al.
CANCER RESEARCH (2015)
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors
Paola Infante et al.
EMBO JOURNAL (2015)
Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
Marcel Kool et al.
CANCER CELL (2014)
Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth
Laura Di Magno et al.
CELL CYCLE (2014)
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition
Yujie Tang et al.
NATURE MEDICINE (2014)
Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex
Chong Gao et al.
BLOOD (2013)
Stemness-related Factor Sall4 Interacts with Transcription Factors Oct-3/4 and Sox2 and Occupies Oct-Sox Elements in Mouse Embryonic Stem Cells
Nobuyuki Tanimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma
Melanie G. Hayden Gephart et al.
JOURNAL OF NEURO-ONCOLOGY (2013)
Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy
Sonia Coni et al.
PLOS ONE (2013)
Sonic Hedgehog-Induced Histone Deacetylase Activation Is Required for Cerebellar Granule Precursor Hyperplasia in Medulloblastoma
Seung Joon Lee et al.
PLOS ONE (2013)
Functional Antagonism between Sall4 and Plzf Defines Germline Progenitors
Robin M. Hobbs et al.
CELL STEM CELL (2012)
Molecular organization of the cullin E3 ligase adaptor KCTD11
Stefania Correale et al.
BIOCHIMIE (2011)
Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma
Enrico De Smaele et al.
NEOPLASIA (2011)
Histone deacetylase and Cullin3-RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
Gianluca Canettieri et al.
NATURE CELL BIOLOGY (2010)
A Novel SALL4/OCT4 Transcriptional Feedback Network for Pluripotency of Embryonic Stem Cells
Jianchang Yang et al.
PLOS ONE (2010)
Regulation and function of Spalt proteins during animal development
Jose F. de Celis et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2009)
Stem Cell Factor SALL4 Represses the Transcriptions of PTEN and SALL1 through an Epigenetic Repressor Complex
Jiayun Lu et al.
PLOS ONE (2009)
Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
Nagma Khan et al.
BIOCHEMICAL JOURNAL (2008)
Medulloblastoma can be initiated by deletion of patched in lineage-restricted progenitors or stem cells
Zeng-Jie Yang et al.
CANCER CELL (2008)
Hedgehog Signaling in Development and Cancer
Jin Jiang et al.
DEVELOPMENTAL CELL (2008)
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
Juergen Cox et al.
NATURE BIOTECHNOLOGY (2008)
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch- dependent ubiquitination
Lucia Di Marcotullio et al.
NATURE CELL BIOLOGY (2006)
Murine inner cell mass-derived lineages depend on SaII4 function
Ulrich Elling et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice
Yupo Ma et al.
BLOOD (2006)
Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1
Jinqiu Zhang et al.
NATURE CELL BIOLOGY (2006)
The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development
Masayo Sakaki-Yumoto et al.
DEVELOPMENT (2006)
A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor
Qing Zhang et al.
DEVELOPMENTAL CELL (2006)
Multisite protein kinase A and glycogen synthase kinase 3β phosphorylation leads to Gli3 ubiquitination by SCFβTrCP
Denis Tempe et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation
Y Pan et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Shh pathway activity is down-regulated in cultured medulloblastoma cells: Implications for preclinical studies
K Sasai et al.
CANCER RESEARCH (2006)
Dual degradation signals control Gli protein stability and tumor formation
EG Huntzicker et al.
GENES & DEVELOPMENT (2006)
Evidence for the direct involvement of βTrCP in Gli3 protein processing
BW Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Hedgehog antagonist RENKCTD11 regulates proliferation and apoptosis of developing granule cell progenitors
B Argenti et al.
JOURNAL OF NEUROSCIENCE (2005)
Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I
JH Jia et al.
NATURE (2004)
RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
L Di Marcotullio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Okihiro syndrome is caused by SALL4 mutations
J Kohlhase et al.
HUMAN MOLECULAR GENETICS (2002)
Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL family
R Al-Baradie et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2002)