Related references
Note: Only part of the references are listed.Centromeres as universal hotspots of DNA breakage, driving RAD51-mediated recombination during quiescence
Xanita Saayman et al.
MOLECULAR CELL (2023)
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization
Jennifer Zagelbaum et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2023)
The Smc5/6 complex is a DNA loop-extruding motor
Biswajit Pradhan et al.
NATURE (2023)
Pol? is phosphorylated by PLK1 to repair double-strand breaks in mitosis
Camille Gelot et al.
NATURE (2023)
Principles and functions of pericentromeric satellite DNA clustering into chromocenters
Franziska Brandle et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2022)
Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations
Ioanna Mitrentsi et al.
MOLECULAR CELL (2022)
Complete genomic and epigenetic maps of human centromeres
Nicolas Altemose et al.
SCIENCE (2022)
An Expanding Toolkit for Heterochromatin Repair Studies
Chetan C. Rawal et al.
GENES (2022)
Imaging the Response to DNA Damage in Heterochromatin Domains
Audrey Chansard et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)
Assignment of structural transitions during mechanical unwrapping of nucleosomes and their disassembly products
Cesar Diaz-Celis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
DNA damage reduces heterogeneity and coherence of chromatin motions br
Maelle Locatelli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)
From fluorescent foci to sequence: Illuminating DNA double strand break repair by high-throughput sequencing technologies
Xabier Vergara et al.
DNA REPAIR (2022)
Search and processing of Holliday junctions within long DNA by junction-resolving enzymes
Artur P. Kaczmarczyk et al.
NATURE COMMUNICATIONS (2022)
Global chromatin mobility induced by a DSB is dictated by chromosomal conformation and defines the HR outcome
Fabiola Garcia Fernandez et al.
ELIFE (2022)
Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
Ondrej Belan et al.
MOLECULAR CELL (2021)
Activation of homologous recombination in G1 preserves centromeric integrity
Duygu Yilmaz et al.
NATURE (2021)
CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy
Simona Giunta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Chromatin mobility and relocation in DNA repair
Noa Lamm et al.
TRENDS IN CELL BIOLOGY (2021)
Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
Ruben Schep et al.
MOLECULAR CELL (2021)
Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance
Anna Fortuny et al.
NATURE COMMUNICATIONS (2021)
The Sound of Silence: How Silenced Chromatin Orchestrates the Repair of Double-Strand Breaks
Apfrida Kendek et al.
GENES (2021)
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation
Clemence Mooser et al.
NATURE COMMUNICATIONS (2020)
Nucleolar Organization and Functions in Health and Disease
Ursula Stochaj et al.
CELLS (2020)
Oncometabolites suppress DNA repair by disrupting local chromatin signalling
Parker L. Sulkowski et al.
NATURE (2020)
JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage
Jeremie Fages et al.
PLOS GENETICS (2020)
Recent advances in the nucleolar responses to DNA double-strand breaks
Lea Milling Korsholm et al.
NUCLEIC ACIDS RESEARCH (2020)
Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin
Rachel Leicher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox
Alexandra C. Vitor et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2020)
Histone methylation and the DNA damage response
Fade Gong et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2019)
H4K20meO recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids
Kyosuke Nakamura et al.
NATURE CELL BIOLOGY (2019)
A Snapshot on the Cis Chromatin Response to DNA Double-Strand Breaks
Thomas Clouaire et al.
TRENDS IN GENETICS (2019)
Reversible histone glycation is associated with disease-related changes in chromatin architecture
Qingfei Zheng et al.
NATURE COMMUNICATIONS (2019)
Molecular Tools to Generate Reactive Oxygen Species in Biological Systems
Ying Xiong et al.
BIOCONJUGATE CHEMISTRY (2019)
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations
Henrike Johanna Gothe et al.
MOLECULAR CELL (2019)
DNA double-strand break repair-pathway choice in somatic mammalian cells
Ralph Scully et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair
Lea M. Korsholm et al.
NUCLEIC ACIDS RESEARCH (2019)
A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair
Aline Marnef et al.
GENES & DEVELOPMENT (2019)
Nuclear actin filaments in DNA repair dynamics
Christopher Patrick Caridi et al.
NATURE CELL BIOLOGY (2019)
The Nucleolus: A Multiphase Condensate Balancing Ribosome Synthesis and Translational Capacity in Health, Aging and Ribosomopathies
Carl C. Correll et al.
CELLS (2019)
Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A
Aniek Janssen et al.
GENES & DEVELOPMENT (2019)
Ten principles of heterochromatin formation and function
Robin C. Allshire et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Dynamic regulation of nucleolar architecture
Attila Nemeth et al.
CURRENT OPINION IN CELL BIOLOGY (2018)
Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function
Julie Ahringer et al.
GENETICS (2018)
Protein Dynamics in Complex DNA Lesions
Radoslav Aleksandrov et al.
MOLECULAR CELL (2018)
Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks
Eva K. Brinkman et al.
MOLECULAR CELL (2018)
Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis
Mikael S. Lindstrom et al.
ONCOGENE (2018)
Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function
Julie Ahringer et al.
GENETICS (2018)
Heterochromatin: Guardian of the Genome
Aniek Janssen et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 34 (2018)
Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures
Thomas Clouaire et al.
MOLECULAR CELL (2018)
Nuclear F-actin and myosins drive relocalization of heterochromatic breaks
Christopher P. Caridi et al.
NATURE (2018)
Nuclear ARP2/3 drives DNA break clustering for homology-directed repair
Benjamin R. Schrank et al.
NATURE (2018)
The Smc5/6 Complex: New and Old Functions of the Enigmatic Long-Distance Relative
Luis Aragon
ANNUAL REVIEW OF GENETICS, VOL 52 (2018)
DNA replication and repair kinetics of Alu, LINE-1 and satellite III genomic repetitive elements
Francesco Natale et al.
EPIGENETICS & CHROMATIN (2018)
The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA
V. Barra et al.
NATURE COMMUNICATIONS (2018)
Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence the outcome of mutagenic DNA repair
Eirini M. Kallimasioti-Pazi et al.
PLOS BIOLOGY (2018)
Variable chromatin structure revealed by in situ spatially correlated DNA cleavage mapping
Viviana I. Risca et al.
NATURE (2017)
Mechanisms of DNA Damage, Repair, and Mutagenesis
Nimrat Chatterjee et al.
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS (2017)
Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair
Fade Gong et al.
JOURNAL OF CELL BIOLOGY (2017)
Phase separation drives heterochromatin domain formation
Amy R. Strom et al.
NATURE (2017)
Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin
Adam G. Larson et al.
NATURE (2017)
Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes
Francois Aymard et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Identification of the elementary structural units of the DNA damage response
Francesco Natale et al.
NATURE COMMUNICATIONS (2017)
Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes
Francois Aymard et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Drosophila Histone Demethylase KDM4A Has Enzymatic and Non-enzymatic Roles in Controlling Heterochromatin Integrity
Serafin U. Colmenares et al.
DEVELOPMENTAL CELL (2017)
Impact of transposable elements on polyploid plant genomes
Carlos M. Vicient et al.
ANNALS OF BOTANY (2017)
Genome Organization Drives Chromosome Fragility
Andres Canela et al.
CELL (2017)
Linking replication stress with heterochromatin formation
Ivaylo Nikolov et al.
CHROMOSOMA (2016)
The molecular basis for centromere identity and function
Kara L. McKinley et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Nucleolar organizer regions: genomic 'dark matter' requiring illumination
Brian McStay
GENES & DEVELOPMENT (2016)
A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin
Aniek Janssen et al.
GENES & DEVELOPMENT (2016)
Real-Time Tracking of Parental Histones Reveals Their Contribution to Chromatin Integrity Following DNA Damage
Salome Adam et al.
MOLECULAR CELL (2016)
DNA Breaks and End Resection Measured Genome-wide by End Sequencing
Andres Canela et al.
MOLECULAR CELL (2016)
Temporal and Spatial Uncoupling of DNA Double Strand Break Repair Pathways within Mammalian Heterochromatin
Katerina Tsouroula et al.
MOLECULAR CELL (2016)
H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex
Giulia Saredi et al.
NATURE (2016)
SCAI promotes DNA double-strand break repair in distinct chromosomal contexts
Rebecca Kring Hansen et al.
NATURE CELL BIOLOGY (2016)
Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability
Peter Zeller et al.
NATURE GENETICS (2016)
The molecular hallmarks of epigenetic control
C. David Allis et al.
NATURE REVIEWS GENETICS (2016)
Breaks in the 45S rDNA Lead to Recombination-Mediated Loss of Repeats
Daniel O. Warmerdam et al.
CELL REPORTS (2016)
Cervantes and Quijote protect heterochromatin from aberrant recombination and lead the way to the nuclear periphery
Taehyun Ryu et al.
NUCLEUS (2016)
Cervantes and Quijote protect heterochromatin from aberrant recombination and lead the way to the nuclear periphery
Taehyun Ryu et al.
NUCLEUS (2016)
Relocalization of DNA lesions to the nuclear pore complex
Catherine H. Freudenreich et al.
FEMS YEAST RESEARCH (2016)
Recombinational DNA repair is regulated by compartmentalization of DNA lesions at the nuclear pore complex
Vincent Geli et al.
BIOESSAYS (2015)
Determinants of mammalian nucleolar architecture
Katherine I. Farley et al.
CHROMOSOMA (2015)
Repeat DNA in genome organization and stability
Jan Padeken et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2015)
A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage
Marjolein van Sluis et al.
GENES & DEVELOPMENT (2015)
Cell-of-origin chromatin organization shapes the mutational landscape of cancer
Paz Polak et al.
NATURE (2015)
Heterochromatic breaks move to the nuclear periphery to continue recombinational repair
Taehyun Ryu et al.
NATURE CELL BIOLOGY (2015)
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging
Weiqi Zhang et al.
SCIENCE (2015)
ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition
Shane M. Harding et al.
CELL REPORTS (2015)
Recognition and Repair of Chemically Heterogeneous Structures at DNA Ends
Sara N. Andres et al.
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS (2015)
Ionizing Radiation-Induced DNA Damage, Response, and Repair
Wil L. Santivasi et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Nuclear position dictates DNA repair pathway choice
Charlene Lemaitre et al.
GENES & DEVELOPMENT (2014)
The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage
Dorthe H. Larsen et al.
NATURE CELL BIOLOGY (2014)
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks
Francois Aymard et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair
Anuja Mehta et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
Double-Strand Break Repair Assays Determine Pathway Choice and Structure of Gene Conversion Events in Drosophila melanogaster
Anthony T. Do et al.
G3-GENES GENOMES GENETICS (2014)
Chromatin Remodeling at DNA Double-Strand Breaks
Brendan D. Price et al.
CELL (2013)
LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation
Irina Solovei et al.
CELL (2013)
Mammalian DNA repair: HATs and HDACs make their mark through histone acetylation
Fade Gong et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2013)
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali et al.
NATURE BIOTECHNOLOGY (2013)
Repair of Double-Strand Breaks by End Joining
Kishore K. Chiruvella et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
DNA Damage Sensing by the ATM and ATR Kinases
Alexandre Marechal et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Genetically encoded system to track histone modification in vivo
Yuko Sato et al.
SCIENTIFIC REPORTS (2013)
Histone marks: repairing DNA breaks within the context of chromatin
Kyle M. Miller et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
Chromatin organization is a major influence on regional mutation rates in human cancer cells
Benjamin Schuster-Boeckler et al.
NATURE (2012)
Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair
Irene Chiolo et al.
CELL (2011)
DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin
Burkhard Jakob et al.
NUCLEIC ACIDS RESEARCH (2011)
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling
Yoko Hayashi-Takanaka et al.
NUCLEIC ACIDS RESEARCH (2011)
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
Clifford P. Brangwynne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Non-B DNA structure-induced genetic instability and evolution
Junhua Zhao et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
High-resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome
Jason S. Iacovoni et al.
EMBO JOURNAL (2010)
Leaping forks at inverted repeats
Dana Branzei et al.
GENES & DEVELOPMENT (2010)
Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation
Daan Peric-Hupkes et al.
MOLECULAR CELL (2010)
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair
Angela T. Noon et al.
NATURE CELL BIOLOGY (2010)
Human rRNA Gene Clusters Are Recombinational Hotspots in Cancer
Dawn M. Stults et al.
CANCER RESEARCH (2009)
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
Andrea Beucher et al.
EMBO JOURNAL (2009)
Double-strand DNA breaks recruit the centromeric histone CENP-A
Samantha G. Zeitlin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology
Brian McStay et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2008)
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
Aaron A. Goodarzi et al.
MOLECULAR CELL (2008)
HP1-β mobilization promotes chromatin changes that initiate the DNA damage response
Nabieh Ayoub et al.
NATURE (2008)
CDK targets Sae2 to control DNA-end resection and homologous recombination
Pablo Huertas et al.
NATURE (2008)
Epigenetic regulation of centromeric chromatin: old dogs, new tricks?
Robin C. Allshire et al.
NATURE REVIEWS GENETICS (2008)
gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
Andrea Kinner et al.
NUCLEIC ACIDS RESEARCH (2008)
Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase
Shigeki Nagai et al.
SCIENCE (2008)
The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus
Jordi Torres-Rosell et al.
NATURE CELL BIOLOGY (2007)
Activation of multiple DNA repair pathways by subnuclear damage induction methods
Christoffel Dinant et al.
JOURNAL OF CELL SCIENCE (2007)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin
Roger A. Hoskins et al.
SCIENCE (2007)
The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks
Michael Kruhlak et al.
NATURE (2007)
Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair
Elijahu Berkovich et al.
NATURE CELL BIOLOGY (2007)
H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability
Jamy C. Peng et al.
NATURE CELL BIOLOGY (2007)
Lamin A-dependent nuclear defects in human aging
P Scaffidi et al.
SCIENCE (2006)
Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region
P Therizols et al.
JOURNAL OF CELL BIOLOGY (2006)
Common themes and cell type specific variations of higher order chromatin arrangements in the mouse
R Mayer et al.
BMC CELL BIOLOGY (2005)
Repeat instability: Mechanisms of dynamic mutations
CE Pearson et al.
NATURE REVIEWS GENETICS (2005)
The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
Y Aylon et al.
EMBO JOURNAL (2004)
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
G Ira et al.
NATURE (2004)
Targeted mutagenesis by homologous recombination in D-melanogaster
YKS Rong et al.
GENES & DEVELOPMENT (2002)
Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III
T Caspari et al.
GENES & DEVELOPMENT (2002)
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress.
IM Ward et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
AHFM Peters et al.
CELL (2001)
Initial sequencing and analysis of the human genome
ES Lander et al.
NATURE (2001)