A novel hollow CuMn-PBA@NiCo-LDH nanobox for efficient detection of glucose in food

Designing a rapid and sensitive glucose detection method is of great significance to public health. Herein, hollow CuMn-PBA@NiCo-LDH nanoboxes (CuMn-PBA@NiCo-LDH NBs) were prepared using acid etching, cation ex-change, and reflux method. The modified electrode exhibited outstanding electrocatalytic performance for glucose oxidation due to the unique hollow nanostructure and synergistic effects. The CuMn-PBA@NiCo-LDH NBs electrode displayed excellent electrocatalytic oxidation activity for glucose in an alkaline solution. Under optimal conditions, the electrode achieved a wide linear range (0.0005-1 mmol L-1, and 1-7 mmol L-1) and high sensitivity (10,300 mu A L/mmol cm-2 and 5310 mu A L/mmol cm-2), with a limit of detection (LOD) of 19 nmol L-1. The feasibility of the sensor applied to the detection of glucose was verified in real food samples through spiked recovery experiments. This electrode material offers an alternative method for the non-enzymatic glucose sensors.

Automated summary

In this study, hollow CuMn-PBA@NiCo-LDH nanoboxes were successfully prepared and exhibited excellent electrocatalytic activity for glucose oxidation due to their unique hollow nanostructure and synergistic effects. The feasibility of using this electrode material for glucose detection in real food samples was verified through spiked recovery experiments.