4.8 Review

Inkjet Printing of Pharmaceuticals

Journal

ADVANCED MATERIALS
Volume -, Issue -, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.202309164

Keywords

bioprinting; digital healthcare and industry 4.0; drop-on-demand and continuous ink-jet additive manufacturing; personalised medications; precision medicine; two- and three-dimensional printing of pharmaceuticals using pharma-inks; quick response (QR) codes and data matrix patterns

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Inkjet printing (IJP) enables precise material deposition for personalized medicine and drug delivery. This review explores the formulation and components of pharma-inks, various substrate materials, and potential improvements through hardware, software, and artificial intelligence integration. Further exploration and optimization are needed to fully harness the healthcare capabilities of IJP.
Inkjet printing (IJP) is an additive manufacturing process that selectively deposits ink materials, layer-by-layer, to create 3D objects or 2D patterns with precise control over their structure and composition. This technology has emerged as an attractive and versatile approach to address the ever-evolving demands of personalized medicine in the healthcare industry. Although originally developed for nonhealthcare applications, IJP harnesses the potential of pharma-inks, which are meticulously formulated inks containing drugs and pharmaceutical excipients. Delving into the formulation and components of pharma-inks, the key to precise and adaptable material deposition enabled by IJP is unraveled. The review extends its focus to substrate materials, including paper, films, foams, lenses, and 3D-printed materials, showcasing their diverse advantages, while exploring a wide spectrum of therapeutic applications. Additionally, the potential benefits of hardware and software improvements, along with artificial intelligence integration, are discussed to enhance IJP's precision and efficiency. Embracing these advancements, IJP holds immense potential to reshape traditional medicine manufacturing processes, ushering in an era of medical precision. However, further exploration and optimization are needed to fully utilize IJP's healthcare capabilities. As researchers push the boundaries of IJP, the vision of patient-specific treatment is on the horizon of becoming a tangible reality. This review delves into inkjet printing's (IJP) potential for precise drug delivery and personalized medicine. It explores pharma-inks in IJP, their formulation, components, and substrates. Various drug delivery routes are covered, while discussing how hardware, software, and artificial intelligence integration could improve IJP's precision and efficiency. Nevertheless, additional exploration and optimization are needed to fully harness IJP's capabilities in healthcare.image

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