Journal
JOURNAL OF NEUROVIROLOGY
Volume -, Issue -, Pages -Publisher
SPRINGER
DOI: 10.1007/s13365-023-01189-1
Keywords
Herpes; Trigeminal schwannoma; Reactivation of virus; Latent period; Varicella zoster; Chicken pox; Homologous side reactivation
Categories
Ask authors/readers for more resources
Varicella-zoster virus can become dormant and reactivate, causing the recurrence of chickenpox, particularly in patients undergoing trigeminal ganglion manipulation surgeries. It is important to obtain a detailed history of chickenpox infection in these patients and diagnose and treat any signs of reactivation promptly.
Varicella zoster is found exclusively in humans. Infected people with this virus result in chickenpox followed by dormant virus within neural ganglia. This dormant virus, once activated, may affect any ganglia or nerves of the body but most commonly involves the thoracic, cervical and trigeminal nerves in decreasing order of frequency. We review three such cases in which manipulation of the trigeminal ganglion resulted in reactivation of varicella at homologous operative sites. Each patient underwent surgeries in which the trigeminal ganglion was manipulated for the resection of trigeminal schwannoma under a microscope through various approaches. All three patients developed reactivation of varicella at homologous operative sites. A thorough history of chickenpox infection should be taken in patients who are undergoing surgeries for trigeminal pathology. Early diagnosis should be made once any vesicular lesions are seen with prompt treatment. Reassurance and counselling are necessary in these patients. If possible, prophylaxis may be started in all such patients. Further studies are warranted to determine the exact cause of reactivation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available