Journal
NEUROSURGERY CLINICS OF NORTH AMERICA
Volume 35, Issue 1, Pages 87-94Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.nec.2023.09.007
Keywords
Epilepsy; Epilepsy surgery; Seizure networks; Stereo-electroencephalography; Local field potentials
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The MGH surgical epilepsy group's shift towards a seizure network paradigm has led to improvements in invasive monitoring methods, with more hypothesis-driven implantations, dominant use of sEEG depth electrodes, wider population coverage, and increased targeting of thalamic nuclei, optimizing the delineation of patients' seizure networks and critical treatment nodes.
The MGH surgical epilepsy group's shift toward a seizure network paradigm has necessitated an evolution in the approach to invasive monitoring for presurgical workup. Implantations have been increasingly hypothesis driven, they are more dominated by sEEG depth electrodes, they serve a broader and younger population, and they more frequently target thalamic nuclei. In these ways, sEEG implantations are optimized for the delineation of patients' seizure networks and the critical nodes to be targeted in treatment.
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