Exploring diagnostic events and first referrals in cancer patient pathways in primary care. A questionnaire survey

Background Cancer diagnostic pathways in general practice are often nonlinear, and several events can delay timely diagnosis.Objectives To explore cancer diagnostic processes in general practice, examining how patients' symptom presentations, sex, and age are associated with the occurrence of predefined potentially delaying events and the first referrals.Method General practices in 3 Danish Regions were invited to participate in a questionnaire survey, addressing patient's symptom presentation, diagnostic process events, and first referral. The general practitioners (GPs) received a list of their incident cancer patients from the preceding 2 years.Results In total 187 general practices participated, including 5,908 patients with the cancer diagnostic pathways initiated in general practice. Presenting with nonspecific symptoms was associated with potentially delaying events, even when the patient also had specific symptoms. Almost half of the patients were referred to a cancer patient pathway (CPP) first, men more often than women, and 10% were referred for acute hospitalization. In 23% of the diagnostic processes, GPs initially treated or referred patients on suspicion of another disease rather than cancer and waited due to normal examinations in 1 out of 20 patients. Excluding sex-specific cancers, these 2 events were more prevalent in women. Men less often complied to the follow-up agreement. Younger patients were less often first referred to a CPP and together with older patients more often first acutely hospitalized.Conclusion In cancer diagnostic processes in general practice, first referrals and the occurrence of potentially delaying events are associated with the patient's age, sex, and specificity of symptoms.

Automated summary

In the diagnostic processes of cancer in general practice, the patient's age, gender, and specificity of symptoms are associated with first referrals and potentially delaying events. Women are more likely to present with nonspecific symptoms and be initially diagnosed with other diseases instead of cancer. Men are more likely to be referred to a cancer patient pathway but have difficulties in compliance with follow-up agreements. Younger patients are less likely to be first referred to a cancer patient pathway.