Journal
JOURNAL OF SAUDI CHEMICAL SOCIETY
Volume 20, Issue -, Pages S463-S475Publisher
ELSEVIER
DOI: 10.1016/j.jscs.2013.01.010
Keywords
Imidazo [2,1-b][1,3,4]thiadiazole; Biological activities; Review
Categories
Ask authors/readers for more resources
Imidazo[2,1-b][1,3,4]thiadiazole heterocycle was discovered during the 1950s. Since then, many newer derivatives are being developed and evaluated for their biological profiles. The derivatives of imidazo[2,1-b][1,3,4]thiadiazoles are widely explored for their biological potential viz. antimicrobial, antifungal, anticancer, anticonvulsant, analgesic, antiinflammatory, anesthetic, and diuretic. They are also reported as potential enzyme inhibitors of cyclooxygenase, Jun kinase, carbonic anhydrase demonstrating their possible significance in target oriented drug design and discovery. The present review highlights the last six decades of research on biological activities of the imidazo[2,1-b][1,3,4]thiadiazoles. (C) 2013 Production and hosting by Elsevier B.V. on behalf of King Saud University.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available