3.8 Article

Pressure-support compared with pressure-controlled ventilation mitigates lung and brain injury in experimental acute ischemic stroke in rats

Related references

Note: Only part of the references are listed.
Article Cardiac & Cardiovascular Systems

Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association

Connie W. Tsao et al.

Summary: This article introduces the latest statistics on heart disease, stroke, and cardiovascular risk factors published by the American Heart Association in conjunction with the National Institutes of Health. The Statistical Update includes data on a range of clinical heart and circulatory disease conditions and their associated outcomes. It serves as a critical resource for the general public, policymakers, healthcare professionals, researchers, and others seeking the best available data.

CIRCULATION (2022)

Review Geriatrics & Gerontology

Microglia Polarization From M1 to M2 in Neurodegenerative Diseases

Shenrui Guo et al.

Summary: Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases, and microglia can be categorized into M1 and M2 types with opposite functions. Modulating microglia M1/M2 polarization shows promising therapeutic potential in neurodegenerative diseases.

FRONTIERS IN AGING NEUROSCIENCE (2022)

Review Endocrinology & Metabolism

Integrative physiological assessment of cerebral hemodynamics and metabolism in acute ischemic stroke

Jui-Lin Fan et al.

Summary: This article discusses the importance of reperfusion treatment in acute ischemic stroke patients and highlights the impact of blood pressure on cerebral perfusion. It emphasizes the importance of effective blood pressure management in the early stages of stroke, and suggests that bedside monitoring of cerebral perfusion and oxygenation can help guide treatment and improve outcomes.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2022)

Review Critical Care Medicine

Physiological and Pathophysiological Consequences of Mechanical Ventilation

Pedro Leme Silva et al.

Summary: Mechanical ventilation is a life-support system used for ventilating the lung during acute lung disease or post-surgery. It differs from normal breathing and may have negative physiological consequences on both the lungs and peripheral organs. Therefore, personalized adjustment of mechanical ventilation parameters is necessary to minimize ventilator-induced lung injury.

SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2022)

Review Clinical Neurology

Global stroke statistics 2022

Tharshanah Thayabaranathan et al.

Summary: This article aims to provide updates on stroke incidence, case-fatality, and mortality rates, as well as identify national stroke clinical registries worldwide. The study reveals disparities and burden in low- and middle-income countries, and limited information from newly identified registries.

INTERNATIONAL JOURNAL OF STROKE (2022)

Article Physiology

Effects of different fluid management on lung and kidney during pressure-controlled and pressure-support ventilation in experimental acute lung injury

Eduardo Butturini de Carvalho et al.

Summary: In an established model of acute lung injury (ALI), a conservative fluid strategy (CF) combined with pressure-support ventilation (PSV) resulted in less lung epithelial cell damage compared to a liberal fluid strategy (LF) combined with PSV. However, LF compared to CF resulted in fewer kidney injury markers, regardless of the ventilatory strategy.

PHYSIOLOGICAL REPORTS (2022)

Article Critical Care Medicine

Effects of positive end-expiratory pressure on lung ultrasound patterns and their correlation with intracranial pressure in mechanically ventilated brain injured patients

Chiara Robba et al.

Summary: This study aimed to evaluate the effects of two levels of positive end-expiratory pressure (PEEP) on lung ultrasound patterns and intracranial pressure (ICP) in brain injured patients. The results showed that increasing PEEP can reduce lung ultrasound scores in the posterior regions and is correlated with changes in respiratory mechanics and clinical variables.

CRITICAL CARE (2022)

Article Anesthesiology

Neurally adjusted ventilatory assist preserves cerebral blood flow velocity in patients recovering from acute brain injury

Gianmaria Cammarota et al.

Summary: This study compared the effects of NAVA and PSV on cerebral blood flow velocity in fifteen adult patients recovering from acute brain injury, finding no significant impact on CBF velocity between the two ventilation modes.

JOURNAL OF CLINICAL MONITORING AND COMPUTING (2021)

Article Anesthesiology

Mechanical ventilation in neurocritical care setting: A clinical approach

Denise Battaglini et al.

Summary: Neuropatients often require invasive mechanical ventilation, and special care is needed to minimize the risk of secondary brain damage. Weaning from MV is particularly challenging in these patients, with a high rate of extubation failure and the need for tracheostomy.

BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY (2021)

Article Critical Care Medicine

Basic ultrasound head-to-toe skills for intensivists in the general and neuro intensive care unit population: consensus and expert recommendations of the European Society of Intensive Care Medicine

Chiara Robba et al.

Summary: This study provides consensus and expert recommendations on the basic skills for head-to-toe ultrasonography in the intensive care setting. A total of 74 statements were generated with strong support for the majority, guiding the development of future training and research projects in critical care ultrasonography.

INTENSIVE CARE MEDICINE (2021)

Review Respiratory System

Prevalence and Outcome of Acute Respiratory Distress Syndrome in Traumatic Brain Injury: A Systematic Review and Meta-Analysis

Tracey H. Fan et al.

Summary: In general, around one in five patients developed ARDS shortly after TBI, with 31% of patients achieving good neurological outcomes at any time; TBI patients without ARDS had higher survival and better neurological outcomes.
Article Critical Care Medicine

Evolution Over Time of Ventilatory Management and Outcome of Patients With Neurologic Disease*

Eva E. Tejerina et al.

Summary: Ventilator management for patients with neurological diseases tends towards more lung-protective strategies over time, with an increasing proportion of patients receiving protective lung ventilation. Independent risk factors for 28-day hospital mortality include age, disease severity, organ dysfunction, and specific neurologic diseases.

CRITICAL CARE MEDICINE (2021)

Article Multidisciplinary Sciences

Comparative effects of dexmedetomidine and propofol on brain and lung damage in experimental acute ischemic stroke

Giselle C. Sousa et al.

Summary: Dexmedetomidine was found to have protective effects in both lung and brain tissues in rats with acute ischemic stroke, reducing inflammation and damage compared to untreated rats. Propofol, on the other hand, showed some negative effects, increasing expression of certain adhesion molecules in the lungs and brain. Dexmedetomidine also showed a greater reduction in inflammatory cytokines compared to propofol in alveolar macrophages and lung endothelial cells.

SCIENTIFIC REPORTS (2021)

Article Respiratory System

The impact of fluid status and decremental PEEP strategy on cardiac function and lung and kidney damage in mild-moderate experimental acute respiratory distress syndrome

Nazareth N. Rocha et al.

Summary: Abruptly decreasing PEEP increases pulmonary arterial hypertension, while combining it with high-volume fluid administration results in more severe lung and kidney damage.

RESPIRATORY RESEARCH (2021)

Article Critical Care Medicine

Lung- and Diaphragm-Protective Ventilation

Ewan C. Goligher et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)

Article Clinical Neurology

Iso-Oncotic Albumin Mitigates Brain and Kidney Injury in Experimental Focal Ischemic Stroke

Renata de S. Mendes et al.

FRONTIERS IN NEUROLOGY (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

Carotid Ultrasound

Leslie M. Scoutt et al.

RADIOLOGIC CLINICS OF NORTH AMERICA (2019)

Article Critical Care Medicine

Lung Purinoceptor Activation Triggers Ventilator-Induced Brain Injury

Adrian Gonzalez-Lopez et al.

CRITICAL CARE MEDICINE (2019)

Letter Critical Care Medicine

Sex susceptibility to ventilator-induced lung injury

Ines Lopez-Alonso et al.

INTENSIVE CARE MEDICINE EXPERIMENTAL (2019)

Article Multidisciplinary Sciences

Evaluation of temperature induction in focal ischemic thermocoagulation model

Helio da Silva et al.

PLOS ONE (2018)

Review Oncology

Heart-Lung interaction in spontaneous breathing subjects: the basics

Sheldon Magder

ANNALS OF TRANSLATIONAL MEDICINE (2018)

Review Oncology

Regional distribution of transpulmonary pressure

Pedro Leme Silva et al.

ANNALS OF TRANSLATIONAL MEDICINE (2018)

Review Oncology

Heart-lung interactions during mechanical ventilation: the basics

Syed S. Mahmood et al.

ANNALS OF TRANSLATIONAL MEDICINE (2018)

Editorial Material Respiratory System

Mechanical ventilation in brain injured patients: seeing the forest for the trees

Andrea Bruni et al.

JOURNAL OF THORACIC DISEASE (2017)

Article Critical Care Medicine

Role of Strain Rate in the Pathogenesis of Ventilator-Induced Lung Edema

Alessandro Protti et al.

CRITICAL CARE MEDICINE (2016)

Review Neurosciences

Development and functions of the choroid plexus-cerebrospinal fluid system

Melody P. Lun et al.

NATURE REVIEWS NEUROSCIENCE (2015)

Editorial Material Multidisciplinary Sciences

NIH to balance sex in cell and animal studies

Janine A. Clayton et al.

NATURE (2014)

Editorial Material Neurosciences

Structure, function, and plasticity of hippocampal dentate gyrus microcircuits

Peter Jonas et al.

FRONTIERS IN NEURAL CIRCUITS (2014)

Article Critical Care Medicine

Mechanical Ventilation Triggers Hippocampal Apoptosis by Vagal and Dopaminergic Pathways

Adrian Gonzalez-Lopez et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)

Article Biochemical Research Methods

Analyzing real-time PCR data by the comparative C-T method

Thomas D. Schmittgen et al.

NATURE PROTOCOLS (2008)

Article Cardiac & Cardiovascular Systems

Echocardiographic measurement of cardiac output in rats

M Slama et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)

Article Biochemistry & Molecular Biology

Decreased surfactant protein-B expression and surfactant dysfunction in a marine model of acute lung injury

EP Ingenito et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2001)