4.7 Article

The effect of mild to moderate COVID-19 infection on the cardiorespiratory fitness of firefighters

Related references

Note: Only part of the references are listed.
Article Immunology

Reduced Exercise Capacity, Chronotropic Incompetence, and Early Systemic Inflammation in Cardiopulmonary Phenotype Long Coronavirus Disease 2019

Matthew S. Durstenfeld et al.

Summary: This study aimed to elucidate the mechanisms of persistent cardiopulmonary symptoms and reduced exercise capacity after SARS-CoV-2 infection. The results showed that more than 1 year after infection, individuals with COVID-19 had cardiopulmonary symptoms and reduced exercise capacity. Cardiopulmonary exercise testing revealed that 49% of symptomatic patients had reduced exercise capacity, significantly higher than the 16% in asymptomatic patients. Inflammatory markers and antibody levels were correlated with the decline in exercise capacity.

JOURNAL OF INFECTIOUS DISEASES (2023)

Review Sport Sciences

Low Cardiorespiratory Fitness Post-COVID-19: A Narrative Review

Fabian Schwendinger et al.

Summary: Patients recovering from COVID-19 commonly experience symptoms of exhaustion, fatigue, and dyspnea, and have exercise intolerance lasting for months. This study aimed to explore the possible mechanisms contributing to exercise intolerance in these patients using cardiopulmonary exercise testing. The findings suggest that respiratory function, cardiovascular function, peripheral factors, and deconditioning may all play a role in the reduced peak oxygen uptake seen in post-COVID-19 patients. However, more research is needed to fully understand these mechanisms and provide individualized diagnosis and treatment.

SPORTS MEDICINE (2023)

Editorial Material Medicine, General & Internal

Predicting the Future in Primary Care Patients Through Graded Exercise Testing

Cemal Ozemek et al.

MAYO CLINIC PROCEEDINGS (2023)

Article Infectious Diseases

COVID-19 reduces cardiorespiratory fitness even months after a mild to moderate acute phase: a retrospective cohort study

Ladislav Stepanek et al.

Summary: Based on repeated cardiopulmonary exercise tests, it was found that COVID-19 significantly reduces cardiorespiratory fitness (CRF) almost one year after infection, although the reduction is modest.

INFECTIOUS DISEASES (2023)

Article Medicine, General & Internal

Effect of COVID-19 on Blood Pressure Profile and Oxygen Pulse during and after the Cardiopulmonary Exercise Test in Healthy Adults

Kamila Mietkiewska-Szwacka et al.

Summary: This study compared the blood pressure and oxygen pulse characteristics between normotensive patients with and without a history of COVID-19 during exercise and recovery. The post-COVID group had higher blood pressure and lower max O-2 pulse during recovery. These findings may have prognostic implications for COVID-19 patients.

JOURNAL OF CLINICAL MEDICINE (2023)

Review Cardiac & Cardiovascular Systems

Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus

Betty Raman et al.

Summary: Long COVID, characterized by persistent COVID-19 symptoms beyond 3 months, is expected to significantly affect the lives of millions worldwide. Cardiopulmonary symptoms are common, along with cardiovascular abnormalities such as inflammation, myocardial infarction, and arrhythmias. The pathophysiological mechanisms behind delayed complications are still not well understood, and COVID-19 is anticipated to alter the long-term trajectory of chronic cardiac diseases. Research is ongoing to evaluate treatment strategies for long COVID and its associated cardiovascular sequelae.

EUROPEAN HEART JOURNAL (2022)

Letter Respiratory System

Exercise capacity impairment after COVID-19 pneumonia is mainly caused by deconditioning

Kathleen Jahn et al.

EUROPEAN RESPIRATORY JOURNAL (2022)

Article Critical Care Medicine

Persistent Exertional Intolerance After COVID-19 Insights From Invasive Cardiopulmonary Exercise Testing

Inderjit Singh et al.

Summary: Patients who have recovered from COVID-19 without cardiopulmonary disease experience a significant reduction in exercise capacity, which may be attributed to reduced systemic oxygen extraction and an exaggerated hyperventilatory response during exercise.

CHEST (2022)

Article Medicine, General & Internal

Cardiopulmonary Exercise Performance and Endothelial Function in Convalescent COVID-19 Patients

Pasquale Ambrosino et al.

Summary: This study aimed to explore the potential association between endothelial dysfunction and reduced cardiopulmonary exercise testing (CPET) performance in COVID-19 survivors. The results showed a significant correlation between endothelium-dependent flow-mediated dilation (FMD) values and CPET parameters ventilation/carbon dioxide production (VE/VCO2) slope and end-tidal carbon dioxide tension (PETCO2). The alteration of endothelial barrier properties may represent a key pathogenic mechanism of the reduced CPET performance in COVID-19 survivors.

JOURNAL OF CLINICAL MEDICINE (2022)

Article Physiology

COVID-19 and athletes: Endurance sport and activity resilience study-CAESAR study

Daniel Sliz et al.

Summary: This study aimed to assess the impact of mild COVID-19 infection on cardiopulmonary exercise test (CPET) performance among endurance athletes. The results showed that mild infection resulted in a decrease in VO2 and HR. It is important for medical professionals and training specialists to be aware of the consequences of mild COVID-19 infection.

FRONTIERS IN PHYSIOLOGY (2022)

Article Multidisciplinary Sciences

Aerobic capacity of professional soccer players before and after COVID-19 infection

Koulla Parpa et al.

Summary: This study investigated the aerobic capacity of professional soccer players before and after COVID-19 infection. The results showed that the infected players had lower VO2max values and VO2 values at respiratory compensation point (RC) after recovery. They also had lower running time on the treadmill and lower velocity at VO2max, but higher heart rate values at ventilatory threshold (VT) and RC post-recovery. These findings suggest that soccer players may not fully recover their aerobic capacity two months after COVID-19 infection.

SCIENTIFIC REPORTS (2022)

Article Medicine, General & Internal

Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults A Systematic Review and Meta-analysis

Matthew S. Durstenfeld et al.

Summary: Reduced exercise capacity is commonly reported among individuals with long COVID-19 symptoms. This study used cardiopulmonary exercise testing to compare the exercise capacity of individuals with and without long COVID-19 symptoms, finding that those with symptoms had lower exercise capacity. In addition to deconditioning, potential mechanisms for exertional intolerance include altered autonomic function, endothelial dysfunction, and muscular or mitochondrial pathology.

JAMA NETWORK OPEN (2022)

Article Respiratory System

Long-term comprehensive cardiopulmonary phenotyping of COVID-19

Lucas M. Kimmig et al.

Summary: Persistent symptoms after COVID-19 infection are common, but not related to the severity of the initial infection. Reduced exercise capacity is mainly seen in patients who required ICU care, possibly due to deconditioning or fatigue rather than cardiopulmonary impairment. Persistent cardiopulmonary impairment is uncommon.

RESPIRATORY RESEARCH (2022)

Letter Respiratory System

Deconditioning as main mechanism of impaired exercise response in COVID-19 survivors

Rocco Francesco Rinaldo et al.

EUROPEAN RESPIRATORY JOURNAL (2021)

Article Cardiac & Cardiovascular Systems

Use of Cardiopulmonary Stress Testing for Patients With Unexplained Dyspnea Post-Coronavirus Disease

Donna M. Mancini et al.

Summary: The study showed that circulatory impairment, abnormal ventilatory pattern, and ME/CFS are common in patients with PASC. Dysfunctional breathing, resting hypocapnia, and ME/CFS may contribute to symptoms. CPET is a valuable tool for assessing these patients.

JACC-HEART FAILURE (2021)

Article Physiology

Impact of COVID-19 on exercise pathophysiology: a combined cardiopulmonary and echocardiographic exercise study

Claudia Baratto et al.

Summary: At the time of hospital discharge, patients with COVID-19 present with reduced functional capacity and exercise hyperventilation. Peripheral factors, namely reduced oxygen extraction (myopathy) and anemia, which are not fully compensated by a supernormal cardiac output response, account for exercise limitation before exhaustion of the respiratory reserve. Enhanced chemoreflex sensitivity, rather increased dead space, mainly accounts for exercise hyperventilation. The pulmonary vascular response to exercise circulation of survived patients with COVID-19 does not present major pathological changes.

JOURNAL OF APPLIED PHYSIOLOGY (2021)

Article Medicine, General & Internal

Predictors of Prolonged Cardiopulmonary Exercise Impairment After COVID-19 Infection: A Prospective Observational Study

Karin Vonbank et al.

Summary: Patients recovering from severe COVID-19 experience negative impacts on maximal and submaximal exercise performance for 3-6 months post-diagnosis, with impaired pulmonary, cardiac, and skeletal muscle function contributing to limitations in VO2 peak. Higher NT-proBNP levels and lower creatinine kinase (CK) levels were observed in severe cases.

FRONTIERS IN MEDICINE (2021)

Article Orthopedics

Cardiopulmonary Exercise Testing to Assess Persistent Symptoms at 6 Months in People With COVID-19 Who Survived Hospitalization: A Pilot Study

David Debeaumont et al.

Summary: The aim of this pilot study is to evaluate physical fitness and its correlation with functional dyspnea in COVID-19 survivors 6 months post-discharge. Results show that persistent dyspnea is associated with reduced physical fitness, with differences between ICU and general ward patients. Tailored rehabilitation interventions may be beneficial for those with persistent dyspnea.

PHYSICAL THERAPY (2021)

Article Cardiac & Cardiovascular Systems

Cardiorespiratory Abnormalities in Patients Recovering from Coronavirus Disease 2019

Yishay Szekely et al.

Summary: Patients recovering from COVID-19 often experience persistent symptoms and a reduction in peak oxygen consumption (Vo2) during exercise, primarily due to a combination of inadequate heart rate and stroke volume reserve.

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY (2021)

Article Medicine, General & Internal

Symptom Persistence Despite Improvement in Cardiopulmonary Health - Insights from longitudinal CMR, CPET and lung function testing post-COVID-19

Mark Philip Cassar et al.

Summary: The study found that cardiopulmonary abnormalities in patients infected with COVID-19 improve over time, but some measures remain abnormal compared to controls. Persistent symptoms at 6 months post-COVID-19 were not significantly associated with objective cardiopulmonary health measures, indicating a complex relationship between symptoms and physiological abnormalities.

ECLINICALMEDICINE (2021)

Article Medicine, General & Internal

Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge

Betty Raman et al.

Summary: The study found that COVID-19 patients discharged from the hospital still experience breathlessness, fatigue, cognitive impairment, and mental health issues. MRI revealed abnormalities in multiple organs, which were linked to inflammation and severity of acute illness.

ECLINICALMEDICINE (2021)

Review Physiology

Measurement and Interpretation of Exercise Ventilatory Efficiency

Devin B. Phillips et al.

FRONTIERS IN PHYSIOLOGY (2020)

Article Cardiac & Cardiovascular Systems

The Relation of Emergency Duties to Cardiac Death Among US Firefighters

Denise L. Smith et al.

AMERICAN JOURNAL OF CARDIOLOGY (2019)

Review Peripheral Vascular Disease

Cardiorespiratory Fitness and Cardiovascular Disease Prevention: an Update

Mouaz H. Al-Mallah et al.

CURRENT ATHEROSCLEROSIS REPORTS (2018)

Review Cardiac & Cardiovascular Systems

Impact of Cardiorespiratory Fitness on All-Cause and Disease-Specific Mortality: Advances Since 2009

Matthew P. Harber et al.

PROGRESS IN CARDIOVASCULAR DISEASES (2017)

Article Public, Environmental & Occupational Health

Cardiorespiratory fitness and cancer incidence in men

Baruch Vainshelboim et al.

ANNALS OF EPIDEMIOLOGY (2017)

Review Physiology

Cardiovascular Strain of Firefighting and the Risk of Sudden Cardiac Events

Denise L. Smith et al.

EXERCISE AND SPORT SCIENCES REVIEWS (2016)

Review Physiology

Extreme sacrifice: sudden cardiac death in the US Fire Service

Denise L. Smith et al.

EXTREME PHYSIOLOGY & MEDICINE (2013)

Review Cardiac & Cardiovascular Systems

Cardiovascular Disease in US Firefighters A Systematic Review

Elpidoforos S. Soteriades et al.

CARDIOLOGY IN REVIEW (2011)

Article Public, Environmental & Occupational Health

Cardiorespiratory Fitness Predicts Cardiovascular Risk Profiles in Career Firefighters

Dorothee M. Baur et al.

JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2011)

Article Medicine, General & Internal

The Utility of Cardiopulmonary Exercise Testing to Detect and Track Early-Stage Ischemic Heart Disease

Sundeep Chaudhry et al.

MAYO CLINIC PROCEEDINGS (2010)