☆ 4.6 Article

Targeting fusion proteins of the interleukin family: A promising new strategy for the treatment of autoinflammatory diseases

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2024)

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Hagop Kantarjian et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

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Article Multidisciplinary Sciences

Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling

Sam Strickson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

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Article Multidisciplinary Sciences

STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus

Peng Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

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Article Biochemical Research Methods

Impact of Signal Peptides on Furin-2A Mediated Monoclonal Antibody Secretion in CHO Cells

Jian'er Lin et al.

BIOTECHNOLOGY JOURNAL (2017)

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Article Engineering, Biomedical

Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery

Li Zhou et al.

BIOMATERIALS (2017)

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Review Dermatology

Anti-interleukin-17 treatment of psoriasis

Sphoorthi Jinna et al.

JOURNAL OF DERMATOLOGICAL TREATMENT (2016)

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Article Neurosciences

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain

Niels Eijkelkamp et al.

JOURNAL OF NEUROSCIENCE (2016)

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Article Immunology

T cell-intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis

Bradley N. Martin et al.

NATURE IMMUNOLOGY (2016)

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Article Rheumatology

Low-Dose IL-2 in the Treatment of Lupus

Masayuki Mizui et al.

CURRENT RHEUMATOLOGY REPORTS (2016)

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Review Oncology

Fusion Proteins for Half-Life Extension of Biologics as a Strategy to Make Biobetters

William R. Strohl

BIODRUGS (2015)

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Review Public, Environmental & Occupational Health

Chimeric Fusion Proteins Used for Therapy: Indications, Mechanisms, and Safety

Brian A. Baldo

DRUG SAFETY (2015)

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Review Pharmacology & Pharmacy

An overview of developing TNF-α targeted therapy for the treatment of psoriasis

Molly Campa et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2015)

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Article Biochemistry & Molecular Biology

AZ17: a new bispecific drug targeting IL-6 and IL-23 with potential clinical use-improves psoriasis in a human xenograft transplantation model

Karin Stenderup et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2015)

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Article Cell Biology

Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies

Liping L. Sun et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

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Review Pharmacology & Pharmacy

Albumin and its application in drug delivery

Darrell Sleep

EXPERT OPINION ON DRUG DELIVERY (2015)

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Editorial Material Rheumatology

Combination Cytokine Blockade: The Way Forward in Therapy for Rheumatoid Arthritis?

Peter C. Taylor et al.

ARTHRITIS & RHEUMATOLOGY (2015)

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Review Public, Environmental & Occupational Health

Side Effects of Cytokines Approved for Therapy

Brian A. Baldo

DRUG SAFETY (2014)

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Article Rheumatology

Effect of IL-17A blockade with secukinumab in autoimmune diseases

Dhavalkumar D. Patel et al.

ANNALS OF THE RHEUMATIC DISEASES (2013)

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Review Immunology

Anti-interferon alpha treatment in SLE

Kyriakos A. Kirou et al.

CLINICAL IMMUNOLOGY (2013)

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Article Immunology

Administration of mycobacterial Ag85A and IL-17A fusion protein attenuates airway inflammation in a murine model of asthma

Rong Jin et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2013)

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Article Rheumatology

Rilonacept for gout flare prevention during initiation of uric acid-lowering therapy: results from the PRESURGE-2 international, phase 3, randomized, placebo-controlled trial

Essack Mitha et al.

RHEUMATOLOGY (2013)

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Review Immunology

Treating inflammation by blocking interleukin-1 in humans

Charles A. Dinarello et al.

SEMINARS IN IMMUNOLOGY (2013)

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Article Rheumatology

Patients non-responding to etanercept obtain lower etanercept concentrations compared with responding patients

A. Jamnitski et al.

ANNALS OF THE RHEUMATIC DISEASES (2012)

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Article Biochemistry & Molecular Biology

The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

Shu Zhu et al.

NATURE MEDICINE (2012)

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Article Orthopedics

IL-4 alone and in combination with IL-10 protects against blood-induced cartilage damage

M. E. R. van Meegeren et al.

OSTEOARTHRITIS AND CARTILAGE (2012)

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Article Endocrinology & Metabolism

Targeting of IL-2 receptor with a caspase fusion protein disrupts autoimmunity in prediabetic and diabetic NOD mice

S. Yarkoni et al.

DIABETOLOGIA (2010)

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Article Immunology

A Th17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-γ production in order to induce airway hyperresponsiveness

Shigeru Ashino et al.

INTERNATIONAL IMMUNOLOGY (2010)

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Article Allergy

Interleukin 17 and RANTES levels in induced sputum of patients with allergic rhinitis after a single nasal allergen challenge

Aleksandra Semik-Orzech et al.

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2009)

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Article Immunology

A Fusion Protein Composed of IL-2 and Caspase-3 Ameliorates the Outcome of Experimental Inflammatory Colitis

Yuval Sagiv et al.

CONTEMPORARY CHALLENGES IN AUTOIMMUNITY (2009)

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