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CELL DEATH AND DIFFERENTIATION (2018)
JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice
Xinxin Song et al.
GASTROENTEROLOGY (2018)
High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis
Ruochan Chen et al.
HEPATOLOGY (2018)
Dinaciclib induces immunogenic cell death and enhances anti-PD1-mediated tumor suppression
Dewan Md Sakib Hossain et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis (Publication with Expression of Concern. See vol. 129, pg. 1803, 2019)
Celine Hernandez et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Lithium chloride attenuates mitomycin C induced necrotic cell death in MDA-MB-231 breast cancer cells via HMGB1 and Bax signaling
Mandieh Razmi et al.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2018)
Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma
Dong-Yan Zhang et al.
THERANOSTICS (2018)
PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism
Changfeng Li et al.
DEVELOPMENTAL CELL (2018)
HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair
Xing Guo et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
ALA-PDT promotes HPV-positive cervical cancer cells apoptosis and DCs maturation via miR-34a regulated HMGB1 exosomes secretion
Yichao Jin et al.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2018)
The anticancer peptide RT53 induces immunogenic cell death
Ewa Pasquereau-Kotula et al.
PLOS ONE (2018)
HMGBI/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma
Cun-Zao Wu et al.
ONCOTARGETS AND THERAPY (2018)
Novel dihydroartemisinin derivative DHA-37 induces autophagic cell death through upregulation of HMGB1 in A549 cells
Xiufeng Liu et al.
CELL DEATH & DISEASE (2018)
Blocking the Feedback Loop between Neuroendocrine Differentiation and Macrophages Improves the Therapeutic Effects of Enzalutamide (MDV3100) on Prostate Cancer
Chao Wang et al.
CLINICAL CANCER RESEARCH (2018)
HMGB1 Inhibits Apoptosis Following MI and Induces Autophagy via mTORC1 Inhibition
Eleonora Foglio et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2017)
ROS-dependent HMGB1 secretion upregulates IL-8 in upper airway epithelial cells under hypoxic condition
H. J. Min et al.
MUCOSAL IMMUNOLOGY (2017)
Elimination of dysfunctional mitochondria through mitophagy suppresses benzo[a] pyrene-induced apoptosis
Durgesh Nandini Das et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
LncRNA MALAT-1 Elevates HMGB1 to Promote Autophagy Resulting in Inhibition of Tumor Cell Apoptosis in Multiple Myeloma
Da Gao et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2017)
Down-regulation of LncRNA TUG1 enhances radiosensitivity in bladder cancer via suppressing HMGB1 expression
Huijuan Jiang et al.
RADIATION ONCOLOGY (2017)
Effect of irinotecan on HMGB1, MMP9 expression, cell cycle, and cell growth in breast cancer (MCF-7) cells
Saeedeh Keyvani-Ghamsari et al.
TUMOR BIOLOGY (2017)
Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes
Jingjing Zhu et al.
NATURE COMMUNICATIONS (2017)
Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity
Akash Patnaik et al.
CANCER DISCOVERY (2017)
HMGB1 promotes differentiation syndrome by inducing hyperinflammation via MEK/ERK signaling in acute promyelocytic leukemia cells
Lanlan Tang et al.
ONCOTARGET (2017)
HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma
Laura Pellegrini et al.
ONCOTARGET (2017)
High mobility group box 1 antagonist limits metastatic seeding in the lungs via reduction of cell-cell adhesion
Adi Karsch-Bluman et al.
ONCOTARGET (2017)
Immunogenic cancer cell death selectively induced by near infrared photoimmunotherapy initiates host tumor immunity
Mikako Ogawa et al.
ONCOTARGET (2017)
Nano-Pulse Stimulation is a physical modality that can trigger immunogenic tumor cell death
Richard Nuccitelli et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)
Rhus coriaria increases protein ubiquitination, proteasomal degradation and triggers non-canonical Beclin-1-independent autophagy and apoptotic cell death in colon cancer cells
Khawlah Athamneh et al.
SCIENTIFIC REPORTS (2017)
[pemetrexed plus sildenafil], via autophagy-dependent HDAC downregulation, enhances the immunotherapy response of NSCLC cells
Laurence Booth et al.
CANCER BIOLOGY & THERAPY (2017)
Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer
Rui Kang et al.
CELL RESEARCH (2017)
Hepatitis B virus X protein stimulates high mobility group box 1 secretion and enhances hepatocellular carcinoma metastasis
Shuzhen Chen et al.
CANCER LETTERS (2017)
The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer
Shu-Wen Hsuan et al.
EUROPEAN JOURNAL OF NUTRITION (2016)
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies
Giuseppa Pistritto et al.
AGING-US (2016)
Autophagy promotes ferroptosis by degradation of ferritin
Wen Hou et al.
AUTOPHAGY (2016)
Blockade of high mobility group box 1 augments antitumor T-cell response induced by peptide vaccination as a co-adjuvant
Kayoko Waki et al.
CANCER SCIENCE (2016)
HMGB1 induces apoptosis and EMT in association with increased autophagy following H/R injury in cardiomyocytes
Fan Ouyang et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2016)
RAGE Enhances TLR Responses through Binding and Internalization of RNA
Damien Bertheloot et al.
JOURNAL OF IMMUNOLOGY (2016)
Cytoplasmic expression of high mobility group B1 (HMGB1) is associated with tumor-infiltrating lymphocytes (TILs) in breast cancer
Hee Jin Lee et al.
PATHOLOGY INTERNATIONAL (2016)
Methylation-mediated repression of microRNA-129-2 suppresses cell aggressiveness by inhibiting high mobility group box 1 in human hepatocellular carcinoma
Zhikui Liu et al.
ONCOTARGET (2016)
HMGB1 overexpression as a prognostic factor for survival in cancer: a meta-analysis and systematic review
Tengyun Wu et al.
ONCOTARGET (2016)
Poly-ADP-ribosylation of HMGB1 regulates TNFSF10/TRAIL resistance through autophagy
Minghua Yang et al.
AUTOPHAGY (2015)
Hypoxia induced HMGB1 and mitochondrial DNA interactions mediate tumor growth in hepatocellular carcinoma through Toll-like receptor 9
Yao Liu et al.
JOURNAL OF HEPATOLOGY (2015)
Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components
Tien-Jen Lin et al.
MOLECULAR CANCER (2015)
Antiandrogen Therapy with Hydroxyflutamide or Androgen Receptor Degradation Enhancer ASC-J9 Enhances BCG Efficacy to Better Suppress Bladder Cancer Progression
Zhiqun Shang et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Aspirin delays mesothelioma growth by inhibiting HMGB1-mediated tumor progression
H. Yang et al.
CELL DEATH & DISEASE (2015)
Upregulation of heat shock proteins and the promotion of damage-associated molecular pattern signals in a colorectal cancer model by modulated electrohyperthermia
Gabor Andocs et al.
CELL STRESS & CHAPERONES (2015)
Macrophage Inflammatory Protein Derivative ECI301 Enhances the Alarmin-Associated Abscopal Benefits of Tumor Radiotherapy
Shiro Kanegasaki et al.
CANCER RESEARCH (2014)
The Four Faces of Autophagy: Implications for Cancer Therapy
David A. Gewirtz
CANCER RESEARCH (2014)
Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review
Ben Lu et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2014)
Knockdown of HMGB1 inhibits growth and invasion of gastric cancer cells through the NF-.B pathway in vitro and in vivo
Jing Zhang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
High Mobility Group Box-1 (HMGB1) Participates in the Pathogenesis of Alcoholic Liver Disease (ALD)
Xiaodong Ge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Therapeutic potential of transgenic mesenchymal stem cells engineered to mediate anti-high mobility group box 1 activity: targeting of colon cancer
Hiroto Kikuchi et al.
JOURNAL OF SURGICAL RESEARCH (2014)
HMGB1 in health and disease
Rui Kang et al.
MOLECULAR ASPECTS OF MEDICINE (2014)
The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics
R. Kang et al.
ONCOGENE (2014)
Targeting HMGB1 inhibits bladder cancer cells bioactivity by lentivirus-mediated RNA interference
W. Wang et al.
NEOPLASMA (2014)
Capsaicin as an inducer of damage-associated molecular patterns (DAMPs) of immunogenic cell death (ICD) in human bladder cancer cells
Donatella D'Eliseo et al.
CELL STRESS & CHAPERONES (2013)
Plasma HMGB-1 after the initial dose of epirubicin/docetaxel in cancer
Tobias Arnold et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2013)
Active immunotherapy for mouse breast cancer with irradiated whole-cell vaccine expressing VEGFR2
Heng-Xiu Yan et al.
ONCOLOGY REPORTS (2013)
Circulating immunogenic cell death biomarkers HMGB1 and RAGE in breast cancer patients during neoadjuvant chemotherapy
Oliver J. Stoetzer et al.
TUMOR BIOLOGY (2013)
Direct molecular interactions between HMGB1 and TP53 in colorectal cancer
Kristen M. Livesey et al.
AUTOPHAGY (2012)
Targeting receptor for advanced glycation end products (RAGE) expression induces apoptosis and inhibits prostate tumor growth
Indira Elangovan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
HMGB1 Promotes Drug Resistance in Osteosarcoma
Jun Huang et al.
CANCER RESEARCH (2012)
p53/HMGB1 Complexes Regulate Autophagy and Apoptosis
Kristen M. Livesey et al.
CANCER RESEARCH (2012)
Cancer Cell Secretion of the DAMP Protein HMGB1 Supports Progression in Malignant Mesothelioma
Sandro Jube et al.
CANCER RESEARCH (2012)
The crosstalk between autophagy and apoptosis: where does this lead?
Claire Gordy et al.
PROTEIN & CELL (2012)
Apicidin and Docetaxel Combination Treatment Drives CTCFL Expression and HMGB1 Release Acting as Potential Antitumor Immune Response Inducers in Metastatic Breast Cancer Cells
Maria Buoncervello et al.
NEOPLASIA (2012)
High Mobility Group Box 1 (HMGB1) Activates an Autophagic Response to Oxidative Stress
Daolin Tang et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
The Receptor for Advanced Glycation End-Products (RAGE) Protects Pancreatic Tumor Cells Against Oxidative Injury
Rui Kang et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Metabolic regulation by HMGB1-mediated autophagy and mitophagy
Rui Kang et al.
AUTOPHAGY (2011)
DAMP-mediated autophagy contributes to drug resistance
Liying Liu et al.
AUTOPHAGY (2011)
High-Mobility Group Box 1 Is Essential for Mitochondrial Quality Control
Daolin Tang et al.
CELL METABOLISM (2011)
HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells
L. Liu et al.
LEUKEMIA (2011)
The redox protein HMGB1 regulates cell death and survival in cancer treatment
Daolin Tang et al.
AUTOPHAGY (2010)
HMGB1 A novel Beclin 1-binding protein active in autophagy
Rui Kang et al.
AUTOPHAGY (2010)
High-mobility group box 1 and cancer
Daolin Tang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2010)
The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival
R. Kang et al.
CELL DEATH AND DIFFERENTIATION (2010)
The Anti-Inflammatory Activity of HMGB1 A Box Is Enhanced When Fused with C-Terminal Acidic Tail
Wei Gong et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2010)
Endogenous HMGB1 regulates autophagy
Daolin Tang et al.
JOURNAL OF CELL BIOLOGY (2010)
HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
D. Tang et al.
ONCOGENE (2010)
Ethyl pyruvate administration inhibits hepatic tumor growth
Xiaoyan Liang et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses
Hideyuki Yanai et al.
NATURE (2009)
HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression
James F. Curtin et al.
PLOS MEDICINE (2009)
Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein
Hirotaka Kazama et al.
IMMUNITY (2008)
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
Lionel Apetoh et al.
NATURE MEDICINE (2007)
The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid
Weiwen Jiang et al.
JOURNAL OF IMMUNOLOGY (2007)
Factors masking HMGB1 in human serum and plasma
Vilma Urbonaviciute et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Cytolytic cells induce HMGB1 release from melanoma cell lines
Norimasa Ito et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Self-eating and self-killing: crosstalk between autophagy and apoptosis
M. Chiara Maiuri et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
The extracellular release of HMGB1 during apoptotic cell death
Charles W. Bell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Role of HMGB1 in apoptosis-mediated sepsis lethality
Shixin Qin et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
High-mobility group box 1 protein (HMGB): Nuclear weapon in the immune arsenal
MT Lotze et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Amphoterin as an extracellular regulator of cell motility: from discovery to disease
HJ Huttunen et al.
JOURNAL OF INTERNAL MEDICINE (2004)
Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion
T Bonaldi et al.
EMBO JOURNAL (2003)
Structural basis for the proinflammatory cytokine activity of high mobility group box 1
JH Li et al.
MOLECULAR MEDICINE (2003)
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
P Scaffidi et al.
NATURE (2002)
HMG 1 and 2: architectural DNA-binding proteins
JO Thomas
BIOCHEMICAL SOCIETY TRANSACTIONS (2001)