4.6 Article

YRNA and tRNA fragments can differentiate benign from malignant canine mammary gland tumors

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Landscape of Clinically Relevant Exosomal tRNA-Derived Non-coding RNAs

Padmanaban S. Suresh et al.

Summary: This article discusses the clinical relevance of exosomal tRNA-derived fragments in pathological conditions and emphasizes their potential as biomarkers.

MOLECULAR BIOTECHNOLOGY (2023)

Review Genetics & Heredity

Disorders and roles of tsRNA, snoRNA, snRNA and piRNA in cancer

Lin Xiao et al.

Summary: Non-coding RNAs play important roles in regulatory functions, and the emergence of high-throughput sequencing technology has expanded our understanding of them. The abnormal expression of tsRNA, snoRNA, snRNA, and piRNA is closely related to the progression of cancer, and these RNAs play important roles in various biological processes.

JOURNAL OF MEDICAL GENETICS (2022)

Article Genetics & Heredity

Micro RNA differential expression profile in canine mammary gland tumor by next generation sequencing

Hui-Wen Chen et al.

Summary: This study identified four differentially expressed miRNAs in canine mammary gland tumors using NGS and qPCR, and analyzed their potential target genes and pathways using gene ontology and KEGG database. The results suggest that these four miRNAs could be promising biomarker candidates for canine mammary gland tumors.
Article Veterinary Sciences

Long non-coding RNA and transfer RNA-derived small fragments in exosomes are potential biomarkers for canine oral melanoma

Al Asmaul Husna et al.

Summary: Novel small non-coding RNAs (sRNAs) have diverse regulatory and functional roles in human and canine oncology. In our study on canine oral melanoma, we identified differentially expressed novel sRNAs in exosomes and validated their potential as biomarkers for accurate diagnosis of this disease.

VETERINARY AND COMPARATIVE ONCOLOGY (2022)

Review Biochemistry & Molecular Biology

Targeting non-coding RNAs to overcome cancer therapy resistance

BaoQing Chen et al.

Summary: Non-coding RNAs (ncRNAs), especially microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), play a crucial role in regulating resistance to different cancer therapies by rewiring essential signaling pathways. ncRNAs have the potential to serve as biomarkers for predicting and detecting resistance to treatment, and targeting ncRNAs may be a strategy to overcome cancer treatment resistance.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)

Article Oncology

Dissecting miRNA facilitated physiology and function in human breast cancer for therapeutic intervention

Dipta Sengupta et al.

Summary: miRNAs play a key role in regulating biological processes and development in animals and plants, they are involved in post-transcriptional gene regulation by preventing translation. Aberrant regulation of miRNAs is associated with cancer development, understanding the biogenesis and function of miRNAs could offer potential therapeutic implications for treating breast cancers.

SEMINARS IN CANCER BIOLOGY (2021)

Article Veterinary Sciences

Bovine serum miR-21 expression affected by mastitis

Yu-Chang Lai et al.

Summary: The levels of circulating miRNAs can be affected by disease, acting as indicators of local disease. In cows with mastitis, miR-21 expression in serum significantly increased, while other miRNAs like miR-146a, miR-155, miR-222, and miR-383 remained unchanged. The upregulation of miR-21 in serum may reflect the impact of local inflammation on systemic reaction.

RESEARCH IN VETERINARY SCIENCE (2021)

Review Medical Laboratory Technology

circRNA-miRNA-mRNA in breast cancer

Meilan Zhang et al.

Summary: Breast cancer has the highest incidence rate among women and the circRNA-miRNA-mRNA axis plays a crucial role in its progression, serving as a potential marker for early diagnosis and treatment.

CLINICA CHIMICA ACTA (2021)

Article Oncology

Circulating tRNA-derived small RNAs (tsRNAs) signature for the diagnosis and prognosis of breast cancer

Jingyi Wang et al.

Summary: This study identified specific tsRNAs in plasma that could distinguish breast cancer patients from healthy controls, with 6 tsRNAs validated as potential diagnostic and prognostic biomarkers for BC. Target genes of these tsRNAs were related to cancer development, indicating their potential clinical utility.

NPJ BREAST CANCER (2021)

Review Oncology

The role of tumor suppressor short non-coding RNAs on breast cancer

Shokooh Salimimoghadam et al.

Summary: This review discusses the tumor suppressing roles of non-coding RNAs in breast cancer, and the mechanisms by which these RNAs target tumor hallmarks, including apoptosis, proliferation, invasion, metastasis, epithelial-mesenchymal transition, angiogenesis, and cell cycle progression.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2021)

Article Biochemistry & Molecular Biology

A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer

Fangfang Jin et al.

MOLECULAR CANCER (2021)

Article Oncology

Identification of melanoma-specific exosomal miRNAs as the potential biomarker for canine oral melanoma

Al Asmaul Husna et al.

Summary: This study identified several differentially expressed miRNAs in exosomes of canine melanoma cells, with certain miRNAs significantly increased in plasma exosomes of metastatic melanoma patients. These miRNAs could serve as potential biomarkers for identifying metastatic melanoma and improving prognosis, with sensitivity and specificity over 85% for distinguishing between non-metastatic and metastatic patients.

PIGMENT CELL & MELANOMA RESEARCH (2021)

Article Oncology

tRNA-derived fragments: tRF-Gly-CCC-046, tRF-Tyr-GTA-010 and tRF-Pro-TGG-001 as novel diagnostic biomarkers for breast cancer

Yue Zhang et al.

Summary: tRF-Gly-CCC-046, tRF-Tyr-GTA-010 and tRF-Pro-TGG-001 are downregulated in breast cancer and early breast cancer and serve as new potential biomarkers for the diagnosis and early diagnosis of breast cancer.

THORACIC CANCER (2021)

Article Biochemistry & Molecular Biology

Ensembl 2021

Kevin L. Howe et al.

Summary: The Ensembl project provides genome annotation and data dissemination services for vertebrate species, including detailed annotation of gene structures, regulatory elements, and variants, as well as inferring the evolutionary history of genes and genomes. They offer integrated genomic data through various means such as genome browsers, search interfaces, specialist tools, and download files. Recent developments include the Ensembl Rapid Release and the SARS-CoV-2 genome browser, aiding in the international scientific response to the COVID-19 pandemic.

NUCLEIC ACIDS RESEARCH (2021)

Article Biochemistry & Molecular Biology

Bovine milk transcriptome analysis reveals microRNAs and RNU2 involved in mastitis

Yu-Chang Lai et al.

FEBS JOURNAL (2020)

Article Veterinary Sciences

Aberrantly expressed snoRNA, snRNA, piRNA and tRFs in canine melanoma

Md Mahfuzur Rahman et al.

VETERINARY AND COMPARATIVE ONCOLOGY (2020)

Review Oncology

tRNA-derived RNA fragments in cancer: current status and future perspectives

Mengqian Yu et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)

Article Veterinary Sciences

Establishment and Characterization of Canine Mammary Gland Carcinoma Cell Lines With Vasculogenic Mimicry Ability in vitro and in vivo

Patricia de Faria Lainetti et al.

FRONTIERS IN VETERINARY SCIENCE (2020)

Review Biochemical Research Methods

Molecular subtyping of cancer: current status and moving toward clinical applications

Lan Zhao et al.

BRIEFINGS IN BIOINFORMATICS (2019)

Article Biochemistry & Molecular Biology

Identification of tRNA-Derived Fragments Expression Profile in Breast Cancer Tissues

Xiaoming Wang et al.

CURRENT GENOMICS (2019)

Review Oncology

Next-generation sequencing-based clinical sequencing: toward precision medicine in solid tumors

Toshifumi Wakai et al.

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2019)

Review Oncology

Clinical target sequencing for precision medicine of breast cancer

Junko Tsuchida et al.

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2019)

Article Biochemistry & Molecular Biology

miRBase: from microRNA sequences to function

Ana Kozomara et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Genetics & Heredity

Translation regulation in skin cancer from a tRNA point of view

Katerina Grafanaki et al.

EPIGENOMICS (2019)

Review Oncology

Roles of tRNA-derived fragments in human cancers

Chunxiao Sun et al.

CANCER LETTERS (2018)

Review Oncology

The dysregulation of tRNAs and tRNA derivatives in cancer

Shi-qiong Huang et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)

Article Urology & Nephrology

YRNA expression in prostate cancer patients: diagnostic and prognostic implications

Yuri Tolkach et al.

WORLD JOURNAL OF UROLOGY (2018)

Review Veterinary Sciences

Current biomarkers of canine mammary tumors

Ilona Kaszak et al.

ACTA VETERINARIA SCANDINAVICA (2018)

Review Oncology

Non-coding RNA networks in cancer

Eleni Anastasiadou et al.

NATURE REVIEWS CANCER (2018)

Article Rheumatology

RNA derived small RNAs in Sjogren's syndrome: Candidate biomarkers?

Jayakanthan Kabeerdoss et al.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES (2017)

Article Multidisciplinary Sciences

tsRNA signatures in cancer

Veronica Balatti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Total Extracellular Small RNA Profiles from Plasma, Saliva, and Urine of Healthy Subjects

Ashish Yeri et al.

SCIENTIFIC REPORTS (2017)

Article Oncology

YRNA expression predicts survival in bladder cancer patients

Yuri Tolkach et al.

BMC CANCER (2017)

Review Oncology

OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer

Alexander A. Svoronos et al.

CANCER RESEARCH (2016)

Review Biochemistry & Molecular Biology

Biogenesis and Function of Transfer RNA-Related Fragments (tRFs)

Pankaj Kumar et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Article Biochemistry & Molecular Biology

Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement

Hani Goodarzi et al.

Review Biochemistry & Molecular Biology

Functional roles of non-coding Y RNAs

Madzia P. Kowalski et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2015)

Editorial Material Biochemistry & Molecular Biology

Canine clues: Dog genomes explored in effort to bring human cancer to heel

Nala Rogers

NATURE MEDICINE (2015)

Article Biochemistry & Molecular Biology

miRBase: annotating high confidence microRNAs using deep sequencing data

Ana Kozomara et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Biochemistry & Molecular Biology

Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer

E. S. Martens-Uzunova et al.

ONCOGENE (2012)

Article Biochemistry & Molecular Biology

miRBase: integrating microRNA annotation and deep-sequencing data

Ana Kozomara et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Pathology

Classification and Grading of Canine Mammary Tumors

M. Goldschmidt et al.

VETERINARY PATHOLOGY (2011)

Article Cell Biology

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)

Yong Sun Lee et al.

GENES & DEVELOPMENT (2009)

Article Veterinary Sciences

The expression of sialyl Lewis X in canine and feline mammary gland tumors

T Nakagawa et al.

JOURNAL OF VETERINARY MEDICAL SCIENCE (2002)