Granulomatous lobular mastitis co-existing with ductal carcinoma in situ: Report of three cases and review of the literature

Article Oncology

Differentiation Between Granulomatous Lobular Mastitis and Breast Cancer Using Quantitative Parameters on Contrast-Enhanced Ultrasound

Liang Yin et al.

Summary: This study investigated the CEUS imaging characteristics of granulomatous lobular mastitis (GLM) and its value in differentiating GLM from breast cancer. The results showed that GLM had higher TTP values and lower WIS values compared to breast cancer. Additionally, a lower percentage of GLM patients exhibited rich vascularity. CEUS can potentially help distinguish GLM from breast cancer by detecting higher TTP and WIS values.

FRONTIERS IN ONCOLOGY (2022)

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Review Mathematical & Computational Biology

Anticancer and Anti-Inflammatory Mechanisms of NOSH-Aspirin and Its Biological Effects

Jun Zhou et al.

Summary: NOSH-Aspirin, generated from NO, H2S, and aspirin, has various essential pathophysiological effects, including anti-inflammatory, analgesic, antipyretic, antiplatelet, and anticancer properties. However, the mechanism of action and regulation of tissue levels of NOSH-Aspirin remain unclear due to its challenging chemical and physical features. This review comprehensively analyzes the biological effects of NOSH-Aspirin and aims to elucidate its disease-protective mechanism.

COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2022)

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Review Surgery

Current Research Describing the Role of CD4+ T Lymphocyte Subsets in the Pathogenesis of Granulomatous Lobular Mastitis

Bilian Zheng et al.

Summary: This article reviews the progress of research on the role of CD4+ T lymphocyte subsets in the development of granulomatous lobular mastitis (GLM). Current studies have confirmed the altered expression of immune molecules in the serum and tissue microenvironment of GLM patients, which may be associated with immune imbalance. The results suggest that immune molecules and immune-related pathways may serve as potential targets and breakthroughs for future GLM treatment.

JOURNAL OF INVESTIGATIVE SURGERY (2022)

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Article Immunology

Cancer Evo-Dev: A Theory of Inflammation-Induced Oncogenesis

Wenbin Liu et al.

Summary: Chronic inflammation plays a key role in cancer development by interacting with genetic predispositions, environmental exposures, and inflammation-related carcinogenic factors. Interventions that reduce inflammation levels, such as exercising and anti-inflammatory medications, can lower the risk of cancer occurrence and recurrence. The Cancer Evo-Dev theory helps understand how inflammation promotes cancer development and provides a foundation for effective prophylaxis and targeted therapy of various cancers.

FRONTIERS IN IMMUNOLOGY (2021)

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Article Oncology