Solar-driven hybrid photo-Fenton degradation of persistent antibiotic ciprofloxacin by zinc ferrite-titania heterostructures: degradation pathway, intermediates, and toxicity analysis

Present work puts forward an efficient strategy to degrade one of the persistent antibiotic contaminants, ciprofloxacin (CIP). Hybrid advanced oxidation process (HAOP) is tailored with a synergy effect between photocatalysis and photo-Fenton catalysis on zinc ferrite-titania heterostructured composite (ZFO-TiO2). The ZFO-TiO2 heterostructured composite enables heterogenous surfaces for enhanced charge separation where HAOP is implemented for CIP degradation with the aid of class AAA solar simulator. The results reveal an enhanced degradation rate of CIP (k(obs) = 0.255 min(-1)), noticeably higher than the conventional TiO2-based photocatalysis. The HAOP system strongly enhances the reaction rates showing five times higher performance as compared to TiO2-based photocatalysis. The substitution reactions for degradation of CIP into its intermediates were analyzed by LC-MS/MS, and the plausible degradation pathways have been graphically modeled identifying 3-phenyl-1-propanol and phenol molecules as less toxic end products. Toxicity of the photodegraded samples reveal 18.1 +/- 1.24% inhibition of V. fischeri at the end of 60-min treatment indicating reduced toxicity of CIP contaminated samples. Antimicrobial inhibition studies on E. coli also corroborate an effective CIP removal (similar to 100%) in less than 90 min. The study puts forward a novel ZFO-TiO2 composite HAOP system for efficient and rapid mineralization of an antibiotic pollutant, extendable towards wide range of pharmaceutical drug degradation studies.

Automated summary

This study proposes an efficient strategy for degrading the persistent antibiotic contaminant, ciprofloxacin (CIP). A hybrid advanced oxidation process (HAOP) is tailored with a synergy effect between photocatalysis and photo-Fenton catalysis on a zinc ferrite-titania heterostructured composite (ZFO-TiO2). The results show that the HAOP system significantly enhances the degradation rate of CIP, outperforming conventional TiO2-based photocatalysis. The study also identifies the intermediates and degradation pathways of CIP, and demonstrates the reduced toxicity of the photodegraded samples.