Journal
CLINICS IN PERINATOLOGY
Volume 42, Issue 4, Pages 839-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.clp.2015.08.010
Keywords
Bronchopulmonary dysplasia; Pulmonary vascular disease; Pulmonary hypertension; Echocardiogram; Inhaled nitric oxide
Categories
Funding
- NHLBI [HL085703, HL068702, U01 HL102235]
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Despite advances in the care of preterm infants, these infants remain at risk bronchopulmonary dysplasia (BPD), which results in prolonged need for supplemental oxygen, recurrent respiratory exacerbations, and exercise intolerance. Recent investigations have highlighted the important contribution of the developing pulmonary circulation to lung development, showing that these infants are also at risk for pulmonary vascular disease (PVD), including pulmonary hypertension (PH) and pulmonary vascular abnormalities. Several epidemiologic studies have delineated the incidence of PH in preterm infants and the impact on outcomes. These studies have also highlighted gaps in the understanding of PVD in BPD.
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