4.1 Article

New Antifungal and Antiviral Dosing

Journal

CLINICS IN PERINATOLOGY
Volume 42, Issue 1, Pages 177-+

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.clp.2014.10.010

Keywords

Neonate; Fluconazole; Amphotericin; Echinocandin; Acyclovir; Ganciclovir

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Neonatal fungal and viral infections are associated with mortality and neurologic impairment among survivors. Advances in pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial medications have led to improved dosing guidance for neonates. This article discusses the basic PK/PD properties and dosing of the most common antifungal and antiviral medications used in neonates.

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